Entry Name Folate biosynthesis
Class Metabolism; Metabolism of cofactors and vitaminsBRITE hierarchy
Pathway map Ortholog table Module M00840 Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF [PATH:map00790 ]
M00841 Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF [PATH:map00790 ]
M00843 L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4 [PATH:map00790 ]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:map00790 ]
Other DBs Reference Authors Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
Title [Cellular Functions and Metabolic Maps] (In Japanese)
Journal Tokyo Kagaku Dojin (1997)
Reference Authors Schwarz G, Mendel RR, Ribbe MW
Title Molybdenum cofactors, enzymes and pathways.
Journal Reference Authors Hanzelmann P, Schindelin H
Title Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism.
Journal Reference Authors Daniels JN, Wuebbens MM, Rajagopalan KV, Schindelin H
Title Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency.
Journal Reference Authors Wuebbens MM, Rajagopalan KV
Title Mechanistic and mutational studies of Escherichia coli molybdopterin synthase clarify the final step of molybdopterin biosynthesis.
Journal Reference Authors Werner ER, Blau N, Thony B
Title Tetrahydrobiopterin: biochemistry and pathophysiology.
Journal Reference Authors Iino T, Tabata M, Takikawa S, Sawada H, Shintaku H, Ishikura S, Hara A
Title Tetrahydrobiopterin is synthesized from 6-pyruvoyl-tetrahydropterin by the human aldo-keto reductase AKR1 family members.
Journal Reference Authors Park YS, Heizmann CW, Wermuth B, Levine RA, Steinerstauch P, Guzman J, Blau N
Title Human carbonyl and aldose reductases: new catalytic functions in tetrahydrobiopterin biosynthesis.
Journal Related map00400 Phenylalanine, tyrosine and tryptophan biosynthesis
KO pathway LinkDB All DBs
