Methanogenic archaeon ISO4-H5: AR505_0631 Help Entry AR505_0631        CDS       T04272                                  Name (GenBank) 2-isopropylmalate synthase LeuA   KO K01649   2-isopropylmalate synthase [EC:2.3.3.13] Organism marc  Methanogenic archaeon ISO4-H5 Pathway marc00290   Valine, leucine and isoleucine biosynthesis marc00620   Pyruvate metabolism marc01100   Metabolic pathways marc01110   Biosynthesis of secondary metabolites marc01210   2-Oxocarboxylic acid metabolism marc01230   Biosynthesis of amino acids Module marc_M00432   Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate Brite KEGG Orthology (KO) [BR:marc00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     AR505_0631   09105 Amino acid metabolism    00290 Valine, leucine and isoleucine biosynthesis     AR505_0631 Enzymes [BR:marc01000]  2. Transferases   2.3  Acyltransferases    2.3.3  Acyl groups converted into alkyl groups on transfer     2.3.3.13  2-isopropylmalate synthase      AR505_0631 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HMGL-like LeuA_dimer HCS_D2 Radical_SAM MrpR_C_cat Motif Other DBs NCBI-ProteinID:  AMH94352 UniProt:  A0A0X8V0K4 LinkDB All DBs Position 639260..640867 Genome browser AA seq 535 aa AA seqDB search MKTQQTSEDVKELKDKFAISQYNQLALSGVDSIKDVEIFDTTLRDGEQTPGIALSPEDKV RIAEALDKLGVRYIEAGFAASSEIERNTIKQINELGLNAQVLSLARSVKGDIDAVIDSGC DYIHTFIATSDLHMKYKLKMTPEEVRAKAVESVEYAREHGLKVQFSCEDATRSDLEFMKS VYKAVQDAGACAINVPDTVGVIIPKAMTYLISELRKDIKIPIAVHCHNDLGLATANTLAA IEAGATIVHSTVNGIGERAGNVAMEEVAINLLANYGIECVNMDKITETSNLIQGITGVHM AVNKALVGANAFAHSSGVHVHGVMGNALTYEPFKPEVIGAQRHIVVGKLSGAHTVEGKLE ELGIKFPAEHMPELMETIKKLAVAGKTVTDAELVAVADDIMWKKSADKKECTLDELTVIT GRSTTPTATVKITRADGTVVTTSDIGVGPVNAAMNAIKKAVNENMTLEEYKLSAITGGSD SMCQVAVTLKNVQGDGNMSFGRAVGPDIVETSVNATMAAINKDFARIKNYIHPEE NT seq 1608 nt NT seq  +upstreamnt  +downstreamnt atgaaaacgcagcaaaccagtgaagacgttaaagagctgaaggataaattcgcgatcagt cagtacaaccagctcgcgctctctggtgtggattccatcaaagatgttgagatcttcgat accacgctgagggacggtgagcagacccccgggatagcgttaagccccgaggacaaggta cgcatcgctgaggccctcgacaagctcggcgtaaggtacatcgaggcgggattcgccgcc tccagcgagatcgaaaggaacacaatcaagcagatcaacgaactgggcctgaacgcccag gtgctgagtctggcgaggtccgtgaaaggggacatcgacgctgtgatagatagcggatgc gattacatccacaccttcatcgcgacctccgacctgcacatgaagtacaagctgaagatg acccccgaggaggtcagggcgaaggccgtggaatccgtggaatacgcacgcgagcatggt ctgaaggtgcagttctcctgcgaggacgccacccgttccgacctggagttcatgaaatcc gtctacaaggcggtacaggatgcgggagcctgcgccatcaacgttcccgacaccgtcgga gtcatcatccccaaggccatgacctatctgatttcggaactgaggaaggacatcaagatt cccatcgcggtgcactgccacaacgatctgggtctggccaccgccaacaccctggcggcc atcgaggcgggagcgaccatcgttcactccaccgtcaacggaatcggcgagagggcggga aacgttgccatggaggaagtggccatcaacctgctggccaactacggtatcgagtgcgtt aacatggacaagatcaccgagacctccaacctgatccagggaatcacgggagtccacatg gctgtcaataaggccctggtgggagccaatgcattcgcgcactcctccggagtgcacgtg cacggggtcatgggcaacgccctgacctacgaaccgttcaaacccgaggtcatcggggca cagaggcacatcgtggtcggcaagctgtccggcgcccataccgtcgagggcaagctggag gagctgggcatcaagttccccgctgagcacatgcccgagctgatggagactatcaagaaa ctggccgtggccggaaagaccgtgaccgacgcagaactggtggccgtggcggacgatatc atgtggaagaagtccgccgacaagaaggagtgcaccctggacgagctgaccgttatcacc ggcaggtccaccacacccaccgccaccgtcaaaatcacccgcgccgacggaaccgtggtc accacttccgacatcggagtgggacccgtcaatgcggccatgaacgctatcaagaaggca gtgaatgagaacatgaccctggaggagtacaaactgtctgccatcaccggcggaagcgac tccatgtgtcaggtcgcggtcaccctcaagaacgtgcagggcgacggcaacatgtccttc ggaagggcagtgggtcccgatatagtggagacttcggtcaacgccaccatggcggccatc aacaaggacttcgcacgcatcaagaattacattcatccggaagagtga

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