Candidatus Mancarchaeum acidiphilum Mia14: Mia14_0676
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Entry
Mia14_0676 CDS
T05015
Name
(GenBank) 2-oxoacid dehydrogenase multienzyme complex, 2-oxoacid decarboxylase (E1) component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
marh
Candidatus Mancarchaeum acidiphilum Mia14
Pathway
marh00010
Glycolysis / Gluconeogenesis
marh00020
Citrate cycle (TCA cycle)
marh00620
Pyruvate metabolism
marh00785
Lipoic acid metabolism
marh01100
Metabolic pathways
marh01110
Biosynthesis of secondary metabolites
marh01120
Microbial metabolism in diverse environments
marh01200
Carbon metabolism
marh01210
2-Oxocarboxylic acid metabolism
Module
marh_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
marh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Mia14_0676
00020 Citrate cycle (TCA cycle)
Mia14_0676
00620 Pyruvate metabolism
Mia14_0676
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mia14_0676
Enzymes [BR:
marh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Mia14_0676
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
PaRep2b
Motif
Other DBs
NCBI-ProteinID:
ASI13979
UniProt:
A0A218NNE2
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Position
complement(637853..638926)
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AA seq
357 aa
AA seq
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MIKEVFNGNIKNMQIMDEDGNIDNSLFPKDLEPKKIIELYKFMSLGRAVSNKLLTLQRLG
KVATFAPLNGEEAVQAGSAYAADASDFIVPTFRNHLPFIMRGVPLENLFIAVKGYEEAYS
SILQKRLTPEAIAVGSQYTQAAGIAFSMKYQKYKNAVIVYGGDGSTSEGDFYEALNFAGV
FNLPIVFVIENNEWAISVPRSSQTASKTLAQKAVAAGVDAIQVDGNDVIAVYKATKDALD
SVKKGGKPMVIEALTYRMGMHTTSDDPTKYRPESEVDGWKPKDPILRLRKYLVSNRLWND
SMDEDMQNQNKSLIDDATAKVNEAKANPKAMFDNVYSFMPETLKEEEDEALKNNFWQ
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgataaaggaagtgttcaatggaaatataaaaaacatgcagatcatggacgaagacggc
aacatagacaacagcctgttcccaaaagatctagaaccaaaaaagataatagaattgtat
aaattcatgagtcttggaagggctgtaagcaataagctgttaacccttcagaggcttgga
aaggtagcgacatttgcccccttaaatggcgaagaagcagtccaggcaggcagcgcatat
gccgcggacgcatcagattttatagtccccacattcaggaaccaccttccattcataatg
agaggtgtgcctttggagaaccttttcattgcagtgaagggctacgaagaagcatattcc
tctatcctacagaaacggctcactccggaggcaatcgctgtaggcagccagtatacccaa
gcggctggcatagcgttcagcatgaagtaccagaagtacaagaatgccgtaatagtatac
ggaggtgatggctcaacatctgaaggcgacttctacgaagctttgaacttcgcaggcgtc
ttcaacctcccaatcgtgtttgtaatagagaacaacgagtgggcaatctcagtcccccgg
tcaagccagacagcttcaaagacattggcgcagaaggcggttgcagcaggagtcgatgca
atacaggttgacggaaacgatgtgattgcagtatacaaggccacaaaggatgctttggat
tcggtaaaaaaaggcggaaagcctatggtaatagaagcattgacatataggatgggaatg
cacaccacttctgatgacccgaccaaatacaggcctgaatccgaagtcgatggatggaag
cccaaggatccaatattgcgcttgaggaagtatcttgtatcaaatagactttggaatgat
tctatggatgaggatatgcagaaccagaacaagtcgcttatagatgacgcgactgcgaaa
gtcaacgaagcaaaggcgaatccaaaggcgatgtttgataatgtatacagtttcatgccc
gaaacactaaaagaggaggaggatgaagcgttgaagaataatttttggcagtga
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