Marinobacterium aestuarii: A8C75_05250
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Entry
A8C75_05250 CDS
T04398
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mars
Marinobacterium aestuarii
Pathway
mars00300
Lysine biosynthesis
mars00550
Peptidoglycan biosynthesis
mars01100
Metabolic pathways
mars01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mars00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A8C75_05250
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A8C75_05250
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A8C75_05250
Enzymes [BR:
mars01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A8C75_05250
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
POR
Motif
Other DBs
NCBI-ProteinID:
ANG61949
UniProt:
A0A1A9EWN4
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All DBs
Position
1196744..1198126
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AA seq
460 aa
AA seq
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MIGSFSLAELVPVLDGRLEGGTGGAISIGRVSTDTRRIQPGDLFVALRGENFDAHDFVAQ
AQSQGAVAAVVERLLPLAIPQLVVADTRLALGAIAQYNRTFFAGPLIAVTGSSGKTSVKE
MLATILAGAGPTLATRGNLNNDIGVPLTLFELEQQHRYAVIEMGASGPGEIDYVSGLARP
DVAVLNNAFGAHLEGFGSLEGVVRAKGEIFNGLNAGGTAVVNADDPHADTWLRQLEQRRV
LSFGLERSDVDVTARDLYYQPNGCHGFELVVGEQRAAVRLRVLGRHNVANALAAAAAAFA
AGLDLSLIVQGLERFEAVAGRMKPIAGVAGCRLIDDSYNANPASVKAAIDVLASLPGERV
LVLGDMAELGPDAAQQHADIGAYAAAAGLDHFYATGPLCRHAVAAYCSQGGSDGQNFASR
AELIGTLNTLAHAQLTLLVKGSRSAAMDQVVSGLAQGEFH
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgatcggaagtttcagtcttgccgagctggtaccggtactggatgggcgtcttgaaggt
ggcactggcggtgccatcagcattggtcgtgtcagtacggatacccgcaggattcagccg
ggtgacctgtttgtggcgttgcgcggtgaaaattttgatgctcacgactttgtcgcccag
gcccaaagccagggcgcggtagcggcggtggtcgaacgcctgctgccactggcgataccg
cagctggttgtcgccgatacacgactcgcgctcggtgccattgcgcaatacaatcgcacc
tttttcgcaggcccactaatagcggtcacaggcagcagcggtaaaacttctgttaaggaa
atgcttgctaccatactggccggcgcaggccctacgctggcaacccgtggcaacctgaac
aacgacatcggcgtgccgctgacgctgttcgagctggaacagcagcaccgttatgccgtg
atcgagatgggcgccagtggccccggcgagatcgactatgtgtcgggactggccaggccc
gatgtggcggtgctgaacaatgcctttggcgcgcacctcgaaggtttcggatcgctggag
ggggtcgtgcgggccaagggcgagatcttcaatggtctcaatgccggtggcacggcggtg
gtcaatgccgatgatccccatgcggatacctggctgcgacagctggagcaacgccgggta
ctgagtttcgggttagagcgcagcgatgtggatgtgacggccagggatctgtattaccag
cccaatggctgtcatggctttgagctggttgtcggtgagcagcgtgctgcggtgcgcttg
cgggtgctgggacgtcacaacgtcgccaatgccctggcggcggcggcggcggcctttgcc
gcgggtctggatctgagcctgatcgtgcaggggctggagcgtttcgaggcggtggccggg
cgcatgaaaccgatagcgggcgtagccggctgtcggctgattgatgacagctataacgcc
aatccggcgtcggtcaaggccgccattgatgtcctggcgagcctgccgggtgaacgcgta
ctggtgctcggtgacatggcggaactcggtcctgatgccgcacagcagcacgccgatatc
ggtgcctatgcggcggcggcggggctggatcacttttatgccaccggccccctgtgtcgt
cacgcggttgcggcctattgcagtcagggcggcagcgatgggcagaattttgctagcaga
gccgagttgatcggcacacttaatacactggcgcatgcgcagctgaccctgctggtcaaa
gggtcgcgcagcgccgctatggatcaggtcgtatctggcctggcgcaaggggaatttcac
tag
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