Mycolicibacterium arabiense: MARA_31180
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Entry
MARA_31180 CDS
T07049
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
marz
Mycolicibacterium arabiense
Pathway
marz00860
Porphyrin metabolism
marz01100
Metabolic pathways
marz01110
Biosynthesis of secondary metabolites
marz01120
Microbial metabolism in diverse environments
marz01240
Biosynthesis of cofactors
Module
marz_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
marz_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
marz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MARA_31180 (hemD)
Enzymes [BR:
marz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MARA_31180 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MARA_31180 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBY49650
UniProt:
A0A7I7RZL9
LinkDB
All DBs
Position
complement(2792179..2793825)
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AA seq
548 aa
AA seq
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MTIRGRKLKPGRITFVGSGPGDPGLLTTRARTVLTNAALAFTDPDVPEAVLALIGSDLPP
ASGPEAPVDDPAGDTDAVPTGAGLPSGVDVRPALGDPAEVAKTLVNEARTGVDVVRLVAG
DPLSVDAVLAEVTAVARTQANFEIVPGLPATTAVPTYAGLPLGSSHTVADVRGDVDWAAL
AAAPGPLILHATASHLPEAARTLIEYGLTDTTPCVVTANGTTCQQRSVETSLSGLLDKAT
LTGSEPAGPLAGPLVATIGKTVANRAKLNWWESRALYGWTVLVPRTKDQAGEMSDRLVGH
GALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFNEFGLDARA
FSGVKIACVGQATADRVRAFGINPELVPSGEQSSLGLLDEFPPYDDIFDPVNRVLLPRAD
IATETLAEGLRDRGWEIEDVTAYRTVRAAPPPAQTREMIKTGGFDAVCFTSSSTVRNLVG
IAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVEALAEHAARLRAEGALPP
PRKKSRRR
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
atgaccatccgagggcgcaagctgaagcccggccgcatcaccttcgtcggttcaggcccg
ggtgaccccggcctgctgacgacgcgggcacgcacagtgctcaccaatgctgcgctggcc
ttcaccgacccagacgtgcccgaggcggtgctggccctgatcgggtcggacctgcctccg
gcatcgggtcccgaagcgccggtggacgacccggcgggcgacaccgacgccgtgccgacc
ggtgcagggctgccgagtggcgtggacgtgcgtcccgcgctcggagacccggccgaggtc
gccaagaccctggtcaacgaggctcgcaccggcgtcgacgtggtgcgactggtcgcgggc
gatccgctgtcggtggacgccgtgctggccgaggtgaccgcggtggcgcggacgcaggcg
aacttcgagatcgtgcccgggctacccgccacgacggccgtgccgacgtatgccggtctg
ccgctgggctcttcgcacaccgtcgccgacgtgcgtggcgacgtggactgggctgcgctg
gccgccgcccccggccctctgatcctgcacgccacggcgtcgcacctgccggaggccgcc
cgcacgctgatcgagtacggcctgaccgacaccacgccctgcgtggtcaccgcgaacggc
accacgtgccagcagcgttcggtcgagacgtcgctgtcgggtctgctcgacaaggccact
ctcacgggcagtgagcctgccggaccgctggcaggcccgttggtggcgacgatcggcaag
accgtcgccaaccgcgcgaagctgaactggtgggagagccgggcgctgtacggctggacc
gtgctcgtcccgcgcaccaaggaccaggccggcgagatgagcgatcgcctcgtcggccac
ggcgcgctgccgatcgaggtgccgaccatcgccgtcgagccgccgcgcagccccgcccag
atggagcgtgcggtcaagggtctggtcgacggccggttccagtgggtcgtgttcacctcc
accaatgccgttcgcgccgtgtgggagaagttcaacgaattcggtctggacgcgcgggcc
ttctccggcgtcaagatcgcgtgcgttggacaggccaccgccgaccgggtgcgcgcgttc
gggatcaatccggagctggtgccctcgggtgagcagtcctcgctgggcctgctcgacgag
ttcccgccgtacgacgacatcttcgacccggtgaaccgggtgctgctgcctcgtgccgac
atcgccaccgagacgctggccgagggtctgcgcgaccgcggctgggagatcgaggacgtc
acggcctaccgcacggtgcgtgccgcaccgccgccggcccagacccgcgagatgatcaag
accggtggcttcgacgcggtgtgcttcacgtcgagttcgacggtgcgcaatctcgtcggc
atcgcgggcaagccgcacgcccggacgatcgtggcgtgcatcgggcccaagaccgccgag
accgcagcggaattcggcctccgcgtcgacgtgcagcccgagacggcggccgtgggcccg
ctggtcgaggcgctcgccgagcacgcagcgcggctgcgggccgagggtgcactgccgcct
ccgcgcaagaagagccgtcgccggtag
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