Myxocyprinus asiaticus (Chinese sucker): 127410030 Help Entry 127410030         CDS       T08782                                  Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism masi  Myxocyprinus asiaticus (Chinese sucker) Pathway masi04020   Calcium signaling pathway masi04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:masi00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     127410030    04020 Calcium signaling pathway     127410030  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:masi04040]     127410030 Ion channels [BR:masi04040]  Voltage-gated cation channels   Ryanodine receptor    127410030 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 Ago_Mid Phage_TAC_15 PAP_RNA-bind EF-hand_1 SET_assoc Motif Other DBs NCBI-GeneID:  127410030 NCBI-ProteinID:  XP_051500982 LinkDB All DBs Position 19:complement(29272159..29406785) Genome browser AA seq 4854 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVAAIEKENRKFCLSAEGLGNRLCYLEPTSEAKYFPP DLCICNFVLEQSLSVRALQEMLAGQNGEGAAQGGGHRTLLYGHAILLRHSLSGMYLTCLK TSRSLTDKLSFDVGLEENSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERFLHL SMSNGSIQVDASFMQTLWNVQPTCSRSSVAVGFLLGGHVMRLFHGHDESLTIPGSDQSEE QQRVVNYEAGKGGSKARSLWRLEPLRISWSGSHIRWGQPFRLRHLSTGHYLGQTEDSGLV LLDRERSDTAATAFCFKSSKEKGDSSPKRDIDGMGMAEIKYGDSFCFIMHVSTGLWLSYQ APDAKSSRLGPLKRRAVLSLEGHMDDGLILQLCQHEESRAARIIRNTTLLFTQFIRGLDG LNGEKAADVCLPVGEVLQTLNDLISYFQQPDTELEHEEKQRQLRSLIKRQDLFKEEGMLS LVSHCIDRLNVYNSAAEFEELAGEEAGDAWKDILNLLYELLAALIRGNRTNCTQFSRKLD WLVSKLERLESSSGILEVLHCILIESPESLNIIQKAHIKSIISLLYKHGRNHKILDVLCS LCVCNGVAVRANQNFICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGMSEGSAQYKKWYFE LIIDQVDHYVTSEPTHLRVGWATTKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGR IPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNVDGFFFPVVSFSA GVKVRFLLGGRHGDFKFLPPAGYAPCYEALLPKEKMRVEPVKEYKRDLEGVRDLLGTTEF LSQASFIPVPVDTSQIVLPPHLENVRDKLAENIHELWGMNKIELGWMYGKVRDDNKRQHP CLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVVQVNVNAEEDLKKMKLPKNYMMANGY KPTPLDLSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNRRNPRLVPYA LLDERTKKSNRDSLREAIRTLVGYGYYIDPPDQETVHKVDEGVESIRVFRVEKTYAVKTG KWYFEFEALTGGDMRVGWARPGCRPDMVLGVDDQAYVFDGYRGRRVHMGSHFFGRTWNKG DVVGCMINMEDKSIIFTLNGEILITNKGSELCFADFETEDGFIPVCSLGLSQIGRMNLGK DASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPEEHPHIEVTRIDGTVDT PPCLKVTHKTFGTQTSNDDMICCRLSMPVEFHSGPWKITDINEVIAEDQRAKKDDGGKID YGSITKYFYSVKVFAGQDPSSVWVGWVTPDYHYYSKHFGLSKVRTVTVTLGDERGRVHES VRRSNCYMVCGGDIVSNSTGRSNTDLKIGCFIDLASGLVSFTANGRELPTVFQVEPNTKL FPAVFVQPTSPNLFQFEFPKISDAMPLSSAIFKSLQGNPEPQCPPRLDVQTIVSVLWSRM PNNFLSVETARVSERHGWVVQCLEPLQMMAVHIPEENRCIDIMELSEHEELRQFHYHTLK LFCALCALGNTRVAHALCSHLDQSQLLYTIDNQFLTGQLREGFYDVLISIHLETAKEAHL MMNNEFIIPVTDETRSIRLFPDDSKRHSLPGVGLSTSITPRLNFSPPCFITTKRVQPLFS PQIPLGILKEKAISMLTEAVQGGGTHIRDPVGGSVEYQFVPILRLIGTLLIMGAMTSEEV RTILLLIDRSVFGDGKEEEEEQQLAVVEQGGEKEEASSNEDKAVEAGEEESKEAKQLPKG LLEKSLPESVKRQMCELLHYFCDCELKQRIEAIVAFADGFVSKLQFNQKFRYNELMQALN MSAAVTAKKTKEFRSPPQEQINMLLNFSVGDDCACPEELQDELQCLHDDLRLHCGIPMEE EEEEQDTSLKGRLMAIIYKIKGRPQKTEERPTEQEQAAPTNLKELISQTMVSWAQECKIQ DPALVRSMFSLLRRQYDGIGELLRALRKSYTISAKSVGDAINLLASLGQIRSLLSVRMGE EEGQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKNKEIAFPKMVASC CRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLACPAMRGSTPLDVAASSVMDNNSLALA LEEPDLEKVVTYLAGCGLQNCPMLIARGYPDIGWNPIEGERYLSFLRFAVFVNGESVEEN ANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPALDLPNPHEGATPTVGEDE EEVAHMGNSIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPTKDLVGIISI PLKMPVVNKDGSVTESDMNASFWPEHKAPMVLFLERVYGIDDQSFLLHLLEVGFLPDLRA SASMDSEVLRTTETALAMNRYIASAVLPLLTRCAHLFAHTEHHAALIDTTLHTIYRLSKG RSLTKAQRDAIEECLMAICTHLRPSMLQQLLRRLVFDVPQLTEYCKMPIKLLTNHYEQNW KYYCLPTGLGSSGMASEEELHLTKKLFWGLFDALSQKKYDADLFKMAMPCLSAIAGALPP DYVDSSPGSTLVKQASVDAQGNFDPQPISTANISLPEKLDYIANKYAEHSHEKWSSEKIT LGWTAGDKVDDKAKTHPLLKPYKTLSEKERETYRYPVKETLKSMLAMGWNIERTKEREAM FQQRESEKQRKTSESSQGEFSPAPQDLENVILSRELQGMVETVAENYHNIWAKKKKIEFD SKGGGGHPMLVPYDTLTAKEKYRDKEKAQELFKFLQVNGYAISRGQKDMEQDSSSMEKRI AYKFLKRLLSYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKILLPLIDQYFKNHCL HFLSSPNINLSSSGYASNKEKEMITSLFCKLAALVRHRISLFGSDSTTMVSCLHILSRSM DFRTVMKSGSELVKAGVRTFFENAAEDLEKTLENLKLGKLGQSRTQMKGVTQIISYTSVA LLPILTVLFQHVTQHQFGAELLLDDIQLSCYRILTSLYSLGTGKNIYVEKQLPVLGECLS TLVGAMPVAFLEPHLNMYNPQSVFNTKTPRERAILSMPDTVDEMCPEMPHLDGLMKDISD ISETGARYTEMPHVIEVILPMLCSYLSYWWAKGPENSPSDSNCCTTVTSEHLSLILGNIL KILNNNLGIDNAPWMKRLAVYTQPIISKASADLLRAHFLPTLEKLKKKTVKVVAEEELLR AESRADTQEAELQILDEFAVLCRDLYAFYPMLIRYVDNNRSKWLKEPDLDSTELFNMVSE IFILWCKSHNFKREEQNFVVQNEINNLAFLTGDSKTKMSKSGGQDQERRGKRRKGELYSV QTSLIVAAHKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKDYLRKNLHLQEKSAD PAVQWQLNLYKDVVVKSEGPPDSEQKVERVQALSAAVFHLEQVEQPLRNKKMVFQKLLSK QRKRAVVACFRMAPLYNLPRHRSINLFLNGYQRLWIETEENSFEEKLVQDLAKTPMTVVE DEEEEEADVQPDPLHQLILHFSHNALTERSFLEEDSLYIAYADMMAKSCAESEEVEEEGK EKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTGTLKLGISILNGGN VRVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAESLGMVTEEGSVNMRD RGSKVLQNDDFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQES ISDFYWYYSGKDVMDEAGQLNFSKALAVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAV VGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMMLSLLEGNVVNGTIGKQMVDTLV ESSGNVEMILKFFDMFLKLKNLTTSDNFKEYDPDCKGVISKKDFHKSMESQKQYTQSEIE FLLSCVEADENDMFNYAEFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLSTFLDLAES VLIYFEPFLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGESE KMELFVNFCEDTIFEMQLASQISEPDVAERPEEDEDEELQSFLEGFSEEEGASLESASAF TAACASVKKSVANFRQMLTLKSMRKQFKKFRKLTIREMITGFFLFFWRLFTGFFKGIFSI IFGFFHIIWSSMFGGGFVEGAKNMKVTDILGNMPDPTQFGIHCDVLEAEKTESNELVVSP DMVQMTGAGAEKLETDMIMDLMTPTGKKEGKHGAEPGLGDVCEVMTEASAPVEKKSQKVA AEKPESETEKADTENQEKEEKAKEETPEESAEAKPSPKAKRGSQKEESQAYMASFFAGLE VYKTKMLNYLARNFYNLRFLALFVAFAINFILLFYKVTGEYDDEEEEGSWGGEDDEGNED DDEGMEYFILQESTGYMAPTLTFLAILHTVISFLCVIGYYCLKVPLVVFKREKEIARKLE FDGLYITEQPSDDDIKGQWDRLVIATPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLG LDKSALDFDPTEEAVVKEASLLSWLSSIDTKYHIWKMGVVLTDNSFLYLIWYTTMSILGH YNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFY NKSEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPSELYRILFDITFFFF VIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEH NLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14565 nt NT seq  +upstreamnt  +downstreamnt atggccgaaggtggtgaaggggaagatgaaattcagttcttacgaactgatgatgaggtg gtgctgcagtgtgtcgctgccattgagaaggagaatcgcaaattctgcctttcagcagag ggactcggcaaccgcctgtgctatctagagcccacatcagaggcgaagtattttcctcct gacctatgcatctgtaactttgtgttggagcaatcgctctcagtgcgggctctacaggag atgctggccgggcagaatggagaaggagctgcacaggggggaggacatcggacactgctc tacggtcatgccatcctcctcaggcattccttaagtggaatgtatctgacttgtctgaaa acatccaggtctctaacagacaagctgtcttttgatgttggcctagaagaaaattcaaca ggggaagcttgttggtggacaattcaccctgcatcaaaacagaggtcagaaggtgaaaag gtccgcattggagatgaccttatcttggtcagtgtgtcctctgagaggttcctgcacctc tccatgtccaatggaagcattcaagtggatgcttctttcatgcaaacactgtggaatgtt cagcctacttgctctagaagcagtgtggctgtaggatttctgctgggtggacatgtgatg cgtttgttccatgggcacgatgagagtctcactataccaggatccgatcaaagcgaagaa caacagagagtggtgaattatgaggctggtaaaggggggtctaaggccaggtctttatgg agactggagcctcttcggataagctggagcggaagccacatcagatggggacagcccttc cgtctacgtcatctctccaccggtcactacctgggccagacagaggacagtggcctggta ctgctggaccgagagaggtctgacactgctgcaactgccttctgtttcaagtcaagcaag gaaaagggtgactccagcccaaagcgagatatagacggtatggggatggcagagatcaaa tacggcgattcattctgtttcatcatgcacgtgtccactggcctgtggctatcctaccag gcacctgatgcaaaatcatctcgactggggccactgaagagaagggccgttctgtctctt gagggccatatggatgatggtctgattttgcagctctgtcagcacgaggagtcccgggct gctcgtatcattcggaacaccacgctcctcttcactcagttcatcaggggtctggatggt ttgaatggggaaaaggcggcagatgtctgtctgcctgtgggtgaagtgctgcagaccctc aatgacctcatcagttactttcagcagcctgacactgagctggaacatgaggagaaacag aggcagctccgatccctcatcaagcgccaggatctgttcaaagaggagggaatgctaagc ctggtctcacactgcattgatcggctgaatgtgtacaacagtgcggctgagtttgaggag ttagcaggcgaggaggcaggagatgcctggaaggacattctcaacctcctctatgagctc ctggctgctctgattcgaggaaacaggaccaactgcacacagttctctcgcaagctggat tggctagtcagcaagctagagcgactggagtcctcatcaggcattttagaggtgcttcat tgtatcctaatcgagagtccggaatctctgaacatcattcaaaaagctcacatcaaatcc attatttccctactgtacaagcatggacgcaaccacaagattctagacgttctctgttcc ctttgtgtctgcaatggtgtggctgtgagagccaatcagaatttcatctgtgaccacctg cttcccaagagagacctgctgctccagactcgactggtcaatgatgttcagagtatgaga cccaacatcttcctgggcatgagtgaaggctcagcacagtataagaagtggtactttgag ctgatcattgatcaagtggaccactatgtgactagtgagcccacccaccttcgtgttggc tgggccaccaccaaaggctacgccccctatcctgggggtggagagggctggggaggaaat ggtgtgggtgacgatctttactcttacgggtttgatgggcttcatctgtggtcagggcgc attccacgggccgtggcctctattaaccagcacttgctgaactcagacgatgtggtgagc tgctgtctggatctcggagcaccgagcatgtctttcagaatcaacggccagccggtgcaa ggcatgtttgaagacttcaacgtagatggcttcttctttcctgtcgtcagtttctctgca ggggtgaaggtccgtttcttgttgggtggtcgccatggagactttaaattcctgcctcca gctggctatgcaccatgttacgaagccctgcttcccaaagaaaagatgcgtgtggagcct gtgaaagagtataaaagagacctggagggagtgagagatctcctgggcacaaccgagttc ctgtcccaggcttccttcattcctgttcctgtcgacaccagccaaattgtcctgcctcca catcttgaaaatgtaagggacaagttagctgagaacatccatgagctctggggcatgaac aaaatagagcttggctggatgtacggcaaggtccgagatgacaacaagagacagcaccct tgtcttgttgacttctctaaactgccagaaacagaaaagaattataacctgcaaatgtca acagaaactttgaagactctacttgcattgggctgccatgttgtacaagtcaatgtaaat gctgaagaagacttgaaaaaaatgaaactccccaagaactacatgatggcaaatggttat aaacccacaccactggacctttctgatgtaaaactgacacctgggcaggaggttctagtt gataaactggctgaaaatgctcataatgtttgggccaaagatcgcattaaacaaggatgg acctatggtattcagcaggatttgaaaaaccgacgcaatccacggctggtgccatatgct ttattagatgaacgtactaagaaatcgaacagagacagtctccgagaggccatccggact ctggtcggatatggatattacatagacccaccagatcaagagactgttcacaaagtggat gagggcgttgaatccatccgtgtcttccgtgtggagaagacctacgctgtgaagacgggg aagtggtattttgaatttgaggctctcaccggaggtgacatgcgtgttggctgggcacgg cctggctgcagacctgatatggtgctgggagtagatgaccaagcctacgtctttgatggc tacaggggccgtcgggtgcatatgggcagtcatttctttggaaggacatggaataaagga gatgtggtgggctgcatgattaacatggaggacaagtccataatattcaccctaaatgga gagatcctaatcaccaacaagggctctgagctttgctttgctgactttgaaactgaagat gggttcatcccagtgtgcagcctgggtctttcccaaattggccgcatgaacttggggaag gatgctagcacttttaagtactacactatgtgtggccttcaggagggctttgaacccttt gccgtcaacatgaatcgagaggtcaccatgtggttcagcaaacgcctgcctacatttgtt aatgtgccagaggaacatccccatattgaggttactagaatagatgggactgtggacact cctccatgtctaaaggtaacgcacaagacatttggtacccaaacaagcaacgatgacatg atctgctgtcgtctgagcatgccggttgagttccattctggcccttggaagatcactgat atcaatgaggtgattgctgaagaccaaagagccaagaaagatgatggaggcaagattgat tatggcagcattacaaagtacttctactctgtgaaagtgttcgccggacaggacccatcg tcagtatgggtgggctgggtgacaccagattaccactactacagcaaacactttggcctc agcaaagttcgcactgtcaccgtaactttgggagatgagcggggacgtgttcatgagagt gtgaggaggagtaactgttacatggtgtgtggtggcgacattgtcagcaactcaacaggt cgtagtaatactgatctgaagattggctgcttcatagatctggcctcaggcctggtctcc ttcactgccaacggcagagagctacctaccgtattccaggttgaacctaacacaaagctg ttccctgctgtatttgtgcaacccacaagtcccaacctgttccaatttgagtttccaaaa atctcagatgcaatgcccctgtcttcagccatttttaagagcttgcaaggaaacccagag ccccagtgtccccctcggctggatgtgcagacaattgtgtctgtgctgtggagtaggatg cccaacaatttcctgtcagtggagacggcccgggtgagtgagaggcatggctgggtggtg cagtgtctggagcccctgcagatgatggctgtgcatatccctgaggaaaacagatgtata gacatcatggagctatcagaacatgaggaactgcggcagttccactatcacactttaaag ctattctgtgccctgtgtgccttgggcaacacccgtgtagctcacgccctctgtagccat cttgatcagtcacagctcctgtacaccattgacaaccaattcctgactggtcagctccgt gaaggcttctacgatgttctcatcagcattcacttggagacagccaaagaggcccatctc atgatgaacaacgagtttataatccccgttacagacgagactcgcagcattcgcctcttc cctgatgattccaagcgtcattctctccctggagtgggcctgagcacctcgatcaccccc cgtctgaacttctcccctccgtgtttcattaccaccaagcgtgtacagcctcttttcagc ccacagattcctttgggtatcttgaaggagaaagccatcagcatgcttacagaggcagtg cagggtggaggtacccacattcgtgatcctgtgggcggaagtgtggagtatcagtttgtg ccgattctcagactgattggcactctgttgatcatgggggcgatgaccagtgaggaggtg aggaccattctgctccttatcgaccgcagtgtgtttggagatggcaaggaggaggaagag gagcagcagctagcagtggtggaacaggggggggagaaagaggaggccagcagtaatgag gataaggcagtggaggcaggggaggaagagagtaaagaggccaagcagcttcccaaaggc ctcctggagaagagcttgcctgaatcggtcaaacgacagatgtgtgaactactgcactac ttctgtgactgcgagctgaagcagcgaattgaggccatcgtcgccttcgcagatggtttt gtgtccaagctccagttcaaccagaagttccgctacaacgagttgatgcaagccctcaac atgtcagccgctgtcactgccaagaagactaaggagtttcgctcacctcctcaagagcag ataaacatgctgctgaacttcagtgttggtgatgattgtgcctgccctgaggagctgcaa gatgagctccaatgcttgcatgatgacctgcgactacattgtggcattcctatggaagag gaggaggaggagcaggacacatctcttaaaggccgtttgatggctataatatacaagatt aaaggtcgtcctcaaaaaactgaggaacgaccaactgagcaagaacaggctgctccaacc aacctgaaggagttgatatctcagacgatggtcagctgggcacaggagtgcaagatccaa gacccggcattggtacgcagcatgttcagccttctgaggaggcaatatgatgggatcggt gagttgctcagggccttgaggaagagctacaccatcagtgcaaagtctgtaggggatgca atcaacctgctggcctcactgggtcagatccgctcactactcagtgtccgcatgggggaa gaggagggccagctcatgattgacggcctgggggacatcatgaacaacaaagtgttctac cagcatccaaatctgatgcgtgttcttggcatgcacgagacggtaatggaggtcatggtc aatgtgctgggcggagacaagaataaggagattgccttccccaaaatggtggccagctgt tgtcgcttcctgtgctacttctgccgcatcagccgacagaatcagaaggctatgtttgac cacctgagctacctcctggagaacagcagcgtgggactggcttgcccagccatgagaggc tccacacctttagatgtggctgcctcctctgtgatggacaataacagcctggctctggct ctagaagaaccagatctagaaaaggtggtgacatatctggcaggctgtgggttacagaac tgcccaatgctcatagccaggggatacccagacattggctggaacccgatagagggagaa cgctatttgtctttcctccggtttgctgtttttgtcaacggtgaaagtgttgaagagaat gctaatgttgtggtgaagctgttgattaggcgtccggagtgctttggacctgctcttaga ggagagggagggcaaggtttactagctgccatgaaggaagccattaagatctcagaagat cctgccttagacctgcccaacccacatgagggggctacacccaccgtcggggaggatgaa gaggaggtcgcacacatgggcaactctattatgtccttctactcagctcttattgatctt ctgggccgttgtgcacctgaaatgcatcttattaacaaaggcaaaggtgaagcattgcgt atccgtgccatccttcgttcactggttcccactaaagatttggtcggaattatcagtatt ccactcaaaatgccagtcgtgaataaagatggcagtgtaactgagtcagacatgaatgct agcttctggccagagcacaaggcacccatggtgcttttcctggagcgtgtgtatggtatt gatgaccaaagcttcttgctgcacctgctggaggtgggcttcctgccagacctgagagca tcagcctccatggactcggaggtgctgagaaccacagagacagcgctggccatgaacagg tacattgcttccgcagtgcttcctctgttgacccgctgtgctcatctgtttgctcacaca gagcaccatgcagctctcattgacactacgctgcacaccatctatcgcctctccaagggc cgatcgctcaccaaagcccagagagatgctattgaggaatgcctaatggccatctgcaca catcttcggccatcaatgctgcagcaacttttgcgtcgtcttgtgtttgatgtgccacag cttacagagtactgcaagatgcccattaagcttttgaccaaccactatgagcagaattgg aaatactactgtctgccaacaggcctgggcagctctggcatggcatcagaggaggaactc catctcaccaaaaaactcttctggggactttttgatgctctttcccagaagaaatatgat gcagatcttttcaaaatggcaatgccatgtttgagtgccatagccggtgccttgccacct gactatgtggattccagcccaggttccactttagttaagcaggcctctgtggatgctcaa ggcaactttgacccccagccgattagcactgctaacatctccctgcctgaaaaattagat tacattgcaaacaagtatgctgagcattcccatgagaaatggtcatctgagaagatcact cttggctggactgcaggagataaagtagatgacaaagctaaaactcaccctcttttgaaa ccatacaaaacactgagtgaaaaggaaagggagacttaccgctaccctgtgaaagagact ctaaagagcatgttggcaatgggatggaacattgagaggaccaaagaaagagaggccatg tttcagcaaagagaatcagaaaaacagcgcaagacatcagagtcttctcagggtgagttt agccctgctccacaggatctggaaaatgtaattctgtcaagagaactacaggggatggtt gaaacagttgcagaaaattaccataacatttgggcgaagaagaagaaaatagaatttgat agtaaaggaggaggaggtcatccaatgttggtaccttatgacactctgacagcaaaggag aagtacagagacaaagagaaggcacaagagctctttaaatttcttcaggtcaatggatac gccattagcagaggtcagaaggacatggagcaagactcctcctctatggagaaaagaatt gcctataagttccttaagaggctcctgagctatgtcgattctgcacaggagtttattgct catcttgaggctatggccacaagtggaaagacagacaaatctccccatgatcaagagatt aaattttttgctaagattctgctgcccctaatagaccaatatttcaagaaccactgcttg cacttcttgtcatcccccaacatcaacctgagcagcagtggctatgcatccaacaaagag aaggagatgatcacaagtctattctgtaagctggcagcacttgtcagacataggatttca ctctttggaagtgactctaccaccatggtgagctgcttgcacattttgtcacgatcaatg gacttcagaactgtcatgaagtctggctcagagctggtgaaggctggtgtcaggacgttc tttgaaaatgcagcagaagatctagagaagactctggaaaacttgaagctggggaagttg ggtcagtcacgcactcagatgaagggcgtcacccagatcatcagctacacctcagtggcc ttgctgcccatcctgactgttctctttcagcatgtcacccagcaccagtttggagcagag ctcctactggatgacattcagctgtcctgctatcgtatcctgaccagcctctactcttta ggcactggcaagaacatctatgttgagaaacagcttcctgtactgggtgaatgtttgtct actttggttggagccatgcctgttgccttcctagagcctcacctgaatatgtacaaccct caatctgtcttcaacaccaagacaccaagagaaagagctattttgagcatgccagacaca gtggatgagatgtgtcctgagatgccccacctggacggccttatgaaggatattagtgac atttctgaaactggagcacgctacacagagatgccacacgtcatcgaggtcatcctaccc atgttgtgtagctacctgtcttactggtgggccaaaggtccagagaactccccaagtgat tccaattgctgcacaaccgtcacgtctgagcatctcagtcttatcctgggcaatatcctc aagattctgaataacaaccttggtattgataacgccccctggatgaaaagacttgcagta tacacccagcctatcattagcaaggctagtgcagatctcttgagggctcacttcctgcca accttggagaagctgaagaagaagacagtgaaagtggtggctgaggaagagctgctgagg gcagaaagcagggcagacactcaggaagctgaactgcaaattctagatgagtttgctgtt ctttgcagggatctgtatgccttctatcccatgctcattcgttatgtggacaataacaga tccaaatggctgaaggaaccagatttagattcaactgaacttttcaatatggtatctgag attttcatcctttggtgcaaatctcataactttaaaagagaagagcaaaattttgtggtg caaaatgagatcaacaacctggcattcctcaccggagacagcaagacaaagatgtcaaaa tctggaggtcaggatcaagagagaagaggaaaaagaagaaaaggagagttgtactccgtc cagacttccctcattgtagcagctcacaagaagatgctgcccattggcctgaacatgtgc actcctggagaccaggagctcatttccctcgccaagatccgctacagtctgaaagacaca gatgatgaggtcaaggattacctgagaaagaacctccatctccaggagaagtctgcagac ccagcggtacagtggcagctaaacctctataaagatgttgtggtgaagagtgagggacct ccagactctgagcaaaaagtggagagagttcaggccctctcagcagccgtattccatttg gaacaggtagagcagcctctgagaaacaagaagatggtgtttcagaagctcctgtcaaag caacgaaagcgtgctgtggtggcttgtttccgtatggcaccactctacaatctaccaagg catcgctcaattaacctgttcctcaatggctatcagagactttggatagagacagaggag aactcctttgaggagaagctagtgcaggacctggcaaaaacacccatgactgtggtagag gatgaagaggaagaggaagctgatgttcagcctgaccctcttcatcagcttatccttcac ttcagtcacaacgctctgactgagagaagtttcctagaagaggattctctgtatatagct tatgctgatatgatggcaaagagctgtgctgagagtgaagaagtagaagaagagggaaaa gaaaaaacttttgaggaaaaagaaatggagaagcagaagattctgtaccagcaggccaga cttcatgctcgtggggctgctgaaatggtattacagatgatcagtgccagtaaaggccga cttggtcccatggtgactggcaccctcaaattgggcatttctatcctaaatggaggcaat gttcgtgtacagcagaaaatgctggattatttgaaagaaaaacgagatgctggcttcttt aaaagtctgtctggactaatgcagtcttgcagtgtgctggatttgaatgcatttgaaagg caaaataaggcagagagtcttggaatggtgactgaagaggggtcagtcaacatgcgtgat cggggttccaaagtacttcaaaatgatgacttcacaaaggatctattcaggtttttgcaa cttctgtgtgagggccacaataatgatttccaaaacttcctgcggacccagactgggaac actactacagtcaacatcatcataagcactgtggactacctattacgcctacaagaatcc ataagcgatttttactggtattactctgggaaagatgtcatggatgaggctgggcaactt aacttctccaaagctttagcagtagccaaacaaatctttaactcactcactgagtatatc cagggcccttgtattgggaatcagcaaagtttggcacacagcaggttgtgggatgcagtg gttgggttcctgcatgttttcgccaatatgcaaatgaaactgtctcaggattctagtcaa attgagctgttgaaggaactgatggacttgcagaaggacatggtggtcatgatgttatct cttttagagggtaatgtggtgaatggaactatcggtaagcagatggtcgacactttagtg gagtcctccggcaatgtggaaatgatccttaagttcttcgacatgttcctcaaactgaag aacttaactacatctgataacttcaaggagtacgacccagactgtaaaggcgttatatcc aagaaggatttccataagtctatggagagccaaaagcaatacacacagtctgagatcgag tttcttctctcctgtgttgaggcagatgaaaatgacatgtttaactatgctgagtttgtg gaacgcttccatgaaccggccaaggacattggctttaatgtggctgtgctgctcacaaac ctatcagaacacatgcccaacgactctcgcctatccactttcttagacctggctgaaagt gtcctcatctactttgaaccattcctgggccgtattgaaatcatgggtggtgccaagagg atagaaagggtttactttgagatcagtgagtctagcagaacccaatgggagaagcctcaa gtcaaagagtccaaaagacagttcatcttcgatgtggtcaatgagggtggtgagagcgag aagatggagttatttgtgaacttctgcgaagacacaatctttgagatgcagctcgcgtct cagatttctgagccagacgttgcagaacgacctgaggaggatgaagacgaagaattgcaa agttttcttgaaggattttctgaggaggaaggtgcctctctcgagtctgcatcggccttt acagcagcttgcgcctctgtcaagaagagcgtggctaatttccgtcaaatgctgactttg aagagcatgcgcaaacagtttaagaaattcagaaaactgaccatcagggaaatgatcaca gggttctttctgttcttctggaggctctttaccgggttcttcaaaggcattttcagcatt atctttggattcttccatattatttggtcctccatgtttggagggggttttgtagagggg gctaagaacatgaaagtgacggatatcttgggtaatatgcctgatcctacacaattcgga atccattgcgatgtactggaagcagaaaaaacagaaagcaacgagctagtggtgtcacca gatatggtacaaatgactggtgctggtgctgagaagctggagactgatatgatcatggat ctcatgacaccaactgggaagaaagaggggaagcatggggcagaacctggtctaggtgat gtctgtgaagttatgactgaggccagtgccccggttgagaagaagagccagaaagtagct gcagagaagccagagtcagagacagagaaagcagacacagagaatcaggagaaagaagag aaggctaaagaggaaacacctgaggaatcagcagaagcaaaaccatcaccaaaagccaaa cgtggatcacaaaaagaagaatctcaagcatacatggctagcttctttgctggacttgaa gtctataaaaccaaaatgctgaactacctggctcgtaatttctacaaccttcgttttctg gctctgtttgtggcctttgccatcaacttcatcctgctcttttacaaggtcactggagaa tatgatgatgaggaagaggaaggatcctggggtggtgaagatgatgagggtaatgaagat gatgatgaaggcatggaatacttcattcttcaggagagcactggctatatggcacccact ttgactttcttggctatattgcacacggtcatctcctttctctgtgtcattggatattac tgcctcaaggttcctttagtcgtgtttaagcgagagaaagaaatcgctaggaagcttgag tttgatggtttgtatattactgagcagccgtccgatgatgacatcaaaggacagtgggat cgtttggttattgcaactccgtccttccctaacaattactgggacaaatttgtgaagagg aaggtcattaataaatatggtgacttgtatggtgctgagcgcatagctgaacttctgggt ttggataagagtgctttggactttgatcccactgaggaagctgtggtgaaggaagcctcc ctgctgtcctggttgagctctattgataccaagtaccacatctggaaaatgggagtggtg ctaactgacaattctttcctctacctgatctggtacaccactatgtctattcttggacat tacaacaacttcttctttgctgctcatttgctggatatagccatgggcttcaagacattg agaaccattctttcttctgtaactcacaatggcaagcagttggtgttgaccgtgggcctc ctggcagtcgtggtctatctgtacaccgtggtggcctttaactttttccgcaagttctac aacaagagtgaggatgaggatgcgcctgacatgaagtgtgatgatatgatgacctgctac cttttccacatgtacgtgggtgtaagagctggcggtggcatcggtgacgaaatcgaggac ccagccggtgacccatccgagctctaccgcattctgtttgatatcaccttctttttcttc gtcatcgtcattctgctggccatcattcagggtttgatcattgatgcctttggtgagttg cgagaccagcaggagcaggtgaaagaggacatggagacaaaatgctttatctgtggaatc gggaatgactattttgacagaaccccacatggatttgagacccataccttacaagagcac aatctggccaactatttattcttcctgatgtatcttatcaacaaagatgagactgaacac actggtcaggagtcgtttgtctggaagatgtatcaggaaagatgttgggatttcttccct gctggagactgtttccggaagcaatatgaggaccagttgggctag

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