Myxocyprinus asiaticus (Chinese sucker): 127455157 Help Entry 127455157         CDS       T08782                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism masi  Myxocyprinus asiaticus (Chinese sucker) Pathway masi04020   Calcium signaling pathway masi04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:masi00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     127455157    04020 Calcium signaling pathway     127455157  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:masi04040]     127455157 Ion channels [BR:masi04040]  Voltage-gated cation channels   Ryanodine receptor    127455157 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  127455157 NCBI-ProteinID:  XP_051578743 LinkDB All DBs Position 17:48999822..49201303 Genome browser AA seq 4887 aa AA seqDB search MAESGDAEDEIQFLRTDDEVVLQCVACIQKENRKFCLSAEGLGNRLCYLEPTSEAKYVPP DLCICSFVLEQSLSVRALQEMLAKTGQNNDQFVRKAAQGGGHRTLLYGHAVLLRHSFSGM YLTCLKTSRSMTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSS ERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSNVEEGYLLGGHVMRLFHGHDEVLTIPG SDQSEEEQRIVNYETGKAGTKARSLWRLEPLRISWCGSHIRWGQPFRLRHLTTGHYLALS EDRGVMLQERERSDTTSTAFCFRASKEKLECTVKRDVEGMGVAEIKYGDSQCFVMHVATG LWLSYQAPDVKSARLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNTTRLFSCF IRELDRLSGTNRVCVLLPIEEVLQTLNDLITYFRLPEAELEHEKKQIKLRSLMNRQNLFK QEGMLSLVSYCIDRLSVYNSAAHFSECAGEEASAAWKDILNLLYELLAALIRGNRNNCTQ FSQNLDWLVSKLERLESSSGILEVLHCILIESPEALNVIQRGHIKTIISLLYKHGRNHKI LDVLCSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFVGVSEGSAQY RKWYFELVIDQVDHFMTGEPSHLRVGWASTKGYAPYPGGGEGWGGNGVGDDLYSYGFDGL HLWSGRIPRTVASVKQHMLMSDDVVSCCMDLNAPSISFRINGQPVQGMFENFNIDGLFFP VVSFSAGVKVRFLLGGRHGDFKFLPPSGYAPCYEALLPKEKMRVEPVKEYKRDADGVRDL LGNTHFTSQASFIPKPVDTSQIVMPPHLEKVRDRLAENIHELWGVNKIELGWSYGKIRED NKRQHPCLVEFSKLPETEKNYNLQMSTETLKTVLALGCHVVQVKLNAEEELKKLKLPKNY LMSNGYKPTPLDLSDVKLTPAQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDVKSKRNP RLVPYALLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQDAGHVVERLSIDKIRFFRVER TYAVKTGKWYFEFEAVTGGDMRVGWARPGCKPDVELGTDDQAYVFDGYRGHRLHMGSRLF GRCWHAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFDSNDGFIPVCSLGLCQV GRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFFNVPKDHKHIAVTR IDGTIDSPPCLKVSHKMFGTQNSNADMVFCRLSMPVEFHSSFKSSIYAHVNGVHEEEPLK LKHRYPVKSMKHSDEGRRTDYSNITTYYYSVRVFAGQDPSCVWVGWVTPDYHYYSNHFNL GKNRTVTVTLGDERGRVHESVKRSNCYMVWGGDVNSAAHSTSRSNVDLEIGCLIDLATGL LAFTVNGKELPSSYQVEPSTKLFPAVFVRPTSSSLFQFELSKIKNAMPISSAIFKSEHKN PVPQCPPRLDVQTINSVLWSRMPNTFLKVETTRVSERHGWMVQCLEPLQMLAVHIPEENR CVDIMELSEQEDLRKFHYHTLKLYCALCAHGNTRVAHALCSHLDQSQLLYTIDNQYLSGM LREGFYNVLISVHLETARAARLMMNNEFIVPITAETRSIRLFPDASKRHQPPGVGLSTSL KPRLNFAPPCFISTKRDQHLYSPEVPLDILKEKAISMLTEAVQGGGDHIRDPVGGSVEYQ FVPILRLISTLLTMAVLTSDDVHKILLLIEPNVFGEQMVEGLRDATMKEGLTGAEEKAVE AGEEEAKDSKVLMKGLLEKKLPESVKRQMCELLHYFCDCELRHRIEAIVSFSDSFVSKLQ YNQKFRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLNFNMGEDCPCPGDIQEELYD FHSELRLHCGVPVEEDEEDLDSSIKGRLLALVYKIKGQPQKSETQPTEKEQTAPSNLKEL ISQTMVSWAQETHIQDPELVRVMFSLLRRQYDSIGELLRAMRKTYTISAGSVQDTIHLLA SLGQIRSLLSVRMGKEEEQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGG GKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLD VAASSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPMLIAKGYPDIGWNPIEGERYLSF LRFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISENPSLDL PSTGPGHASDVSTEGEEEEEVVHMGNAILSFYSALIDLLGRCAPEMHLINKGKGEALRIR AILRSLVPTEDLVGIISIPLKMPVLNKDGSVTEPDVSATFCPDHKAPMVLFLDRVYGIED QSFLLHLLEVGFLPDLRASASLDTEALRTTETALAMNRYIGSAMLPLLTRCAPHFSGTEH HAMLIDSTLYTIYRLSKGCSLTKAQRDAIEECLLAVCKYLRPSMLQHLLRRLVFDVPLLS EYCKMPLKLLTNHYEQNWKYYCLPSGWGSYGLASEEELLLTKKIFWGIFDSLSQKKYEQE LFKMAMPCLSAIAGALPPDYIDSSLSTTLEKPVSVDAQGNFEPKPINTANICLPEKLEHI ANKYAEHSHEKWSSEKVILGWKYGENIDEKAKTHSMLRSYKSLTEKEKEVYRWTVRESLK SMLAMGWSIDRTKEGESMFQQREIEKMRRISQASQGNSFSPAPLDMSNVLLSRELQSMVE VVAENYHNIWAKKKKSELGTRGGGTHPLLVPYDTLTAKEKAKDREKAQDLFRFLQINGYA ITRGLKDMEQDSSSMEKRFAYKFLKKLLKYVDSAQEFIAHLEAMATSGKNDKSPHEQEIK FFAKVLLPLIDQYFKNHSLYFLSSPTKNLSSSGYASNKEKEMVTSLFCKLAALVRHRISL FGSDSTTIVSCLHILAHTLDTRTVMKSASELVKAGLRTFFENAAEDLEKTLENLKLGKFT HSRSQMKGVSQNINYTTVALLPILTALFEHITEHQFGSDLLLDDVQVSCYRILTSLYSLG TGKNIYVERQLPALGECLATLAGAMPVAFLEPQLNKHNTCSVFNTKTSRERAILGMPECV DEMCPDMPRLDGLMKDINDMSESGARYTEMPHVIEVVLPMLCNYLSYWWERGPENRCESA AVCSTTVTSEHLSVILGNILKILNSNLGIDEASWMKRIAVYAQPIISKARADLLKTHFLP TLEKLKKKTVKVVMEEELLKADGKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNR SRWLKEPDADSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDSKTKLAK SFLPKSGGQDQERKHKKRRGDFYSIQTSLIVSALKKMLPIGLNMCTPGDQELILLAKTRY SLKDTDDEVKQHIRQNLHLQEKSEDPAVRWQLNLYKDVIVKTEETSDPERTVERIQSISA AVFHLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLTGYQRLW IEAEMYSFEEKLVQDLAKTQPKSDEEEEEITDTQPDPLHQLILHFSHNALTERSCLEEDQ LYIAYADMMAKSCAENEEEDEEGKEKTFEEKEMEKQKTLYQQARLHDRGAAEMILQMISA SKGGLGSMVTFTLKLGISILNGGNTLVQQKMLDYLKEKRDVGFFKSLSGLMQSCSVLDLN AFERQNKAEGLGMVTEEGSINVRERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRT QTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEAGQRNFSKALAVAKQIFNSL TEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMIV MMLSLLEGNVVNGTIGKQMVDTLVESSNNVEMILKFFDMFLKLKDLTTSENFKEHDPDRK GVISKKEFQKSMENQKQYSQSEIEFLLSCAEADENDMFNYEEFVKRFHEPAKDIGFNVAV LLTNLSEHMPHDSRLATFLNLAESVLNYFEPFLGRIEIIGGAKRIERVYFEISESSRTQW EKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASLISEPDAAERPEDDED EDAQSVAENLEEEEEDGALESSSAFTLACVSMRKSLANLRQMLTLKSMKRQYRRLRKMSV REMIRGFFYFFWMIFTGMFRFFYNLMWGFFHILWSTLFGGGLVEGAKNMKVTDILGNMPD PTQFGIHGDVLEIEKLEYCDMSSVAELRHIAAGEQTEMDLMSELMNIHPRREGGKHGMEP GLGDVSEVVGEDTPSLASAVHQKKAQEAATKQASETETKCESEKADMEDGEKKDQDKSKE EVLKDPLSKEDKKPMKKRRGQRKEPAEAFMASFFAGLDVYQTKMLNYLARNFYNLRFLAL FVAFAINFILLFYKVTGEDSDDLDPWTRREEDDDEGVVEYFVLQESTGYMAPTLRFLAVM HTLISFLCVVGYYYLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINTP SFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEETVIKDASLLSWLSS IDTKYHIWKMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSV THNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSADEDEPDMKCDDMMTCYLFHMYVG VRAGGGIGDEIDDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQV KEDMETKCFICGIGNDYFDTTPHGFESHTLQEHNLANYLFFLMYLINKDETEHTGQESYV WKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14664 nt NT seq  +upstreamnt  +downstreamnt atggcggaaagcggagacgcggaggacgagattcagttcttgcggaccgatgatgaggtg gtcctgcagtgtgttgcctgcattcagaaagagaaccgtaaattctgtctgagcgctgag ggtttggggaaccgactttgttacctggagcccacgtcagaagccaagtatgttcctcca gatctgtgtatctgtagttttgtgctggagcagtcgctgtctgtgcgtgcgctacaggag atgctcgccaaaaccggacaaaacaacgaccagtttgttagaaaggcggcgcagggcgga ggtcacaggacgttactgtacggtcacgctgtcctgctcaggcactccttcagtggaatg tatctgacctgcttgaagacctcaagatctatgacagataaattgtcttttgatgtggga ctgcaagaggactcgacaggagaggcgtgctggtggacgattcatcctgcgtctaaacag agatcagagggtgagaaagttcgaattggagatgatctcatactcgtcagtgtttcatct gaacgatatctacatctgtccatatccaatggcaacatccaggtggacgcgtccttcatg cagacactgtggaacgtccatcccacctgctccgggagcaacgtggaggaaggatacctt cttggtggtcatgtgatgcgtctttttcacggccacgatgaagtgctgacaatcccagga tctgatcagagtgaggaagagcagaggatagtgaactatgagactggtaaagctggaact aaagctcgatctctctggagactggaaccgttacggatcagttggtgtggaagtcacatc cgctggggccaaccctttcgtctgcgtcacctgaccactggtcactacctggcgctgtcc gaagacagaggagtcatgctgcaggagagagagagatcggacaccacgtccactgcattc tgcttcagagcttcaaaggaaaagttggaatgcactgtgaagcgtgatgtggaggggatg ggtgtagcagaaatcaaatatggagactctcagtgtttcgtgatgcatgtggcaacggga ctgtggctgtcttatcaagcgccagacgtcaaatcggctcgactgggacctctcaaacga cgagcgtgtcttcattcagagggacacatggatgacggtttgacgttacaacgttgtcaa catgaagagtcacgagctgctcgaatcatccgcaacaccacacgactcttcagttgcttc atcagagaactggaccgtttgagtggtacgaaccgtgtgtgcgtgcttctgcccatcgaa gaggttcttcagacgctcaatgatctcatcacgtacttcagactgcccgaagccgagctg gaacatgagaagaaacagatcaaactgcgttcactaatgaaccgtcagaatctcttcaaa caggaggggatgctgtctctggtgtcttactgcatcgatcggttgagtgtttataacagt gcggctcatttcagtgagtgtgcgggtgaagaggccagtgcggcgtggaaagacattctc aacctgctctacgagctgctggccgctctcatcagaggaaacaggaataactgtacacag ttctcacagaatctggattggctggtcagtaaactggagagactggagtcttcttcaggg atcttggaggttcttcactgtattctgattgagagtcctgaagctctgaacgtcatccag agaggacacataaagaccatcatctcgctgctctataaacacggacgcaaccacaagatc ctggacgttctctgctctctctgtgtgtgtaacggagtcgctgtcagagccaatcagaat ctgatctgtgatcacctgctgcccaaacgagacctgctcctgcaaacacgattggtcaac gacgtacaaagcatgcggcccaatatcttcgtaggcgtcagtgaaggttcagcccagtac aggaagtggtactttgagctggtgatcgatcaggtggatcatttcatgacgggcgagccg tcacacctgcgggtgggctgggcatccactaaaggttacgccccttacccgggcggagga gaggggtgggggggcaacggggtcggtgatgatctctactcctacggctttgatggactc cacctgtggtcaggacggattccacggaccgttgcgtcagtcaagcagcacatgttaatg tctgatgatgtggtcagctgttgtatggatctgaacgctcccagtatctccttcaggatc aatggacagcccgtgcagggaatgttcgagaacttcaacatcgatgggctgtttttcccc gtggtcagcttctccgctggggtcaaggtgcgtttcctgttaggtggtcgtcatggagat tttaagttcctgcctccgtcgggttacgcgccgtgttatgaagctctgctgccgaaggag aagatgcgagtcgagccggtgaaagagtacaagagagacgccgatggagtgagagactta ctgggcaacacacacttcacctcacaggcatcgttcatacccaaacctgtggacacatca cagatcgtcatgcctcctcatctggagaaggttcgagatcgtttggctgaaaacatccat gagctgtggggcgtgaacaagatcgagctgggctggtcgtacgggaagatcagagaagat aataagcgtcagcacccatgtctggtggaattctccaaactgcctgaaactgagaagaac tacaacttacagatgtcgacagaaacactcaagactgtactggctttgggttgtcatgtt gttcaggtgaaactgaatgctgaagaggaactgaagaaactcaaacttccaaagaactat ttgatgtctaatggatataaacccacaccgctggatctgtctgatgtgaaactgaccccg gctcaggagctgctggtggacaaactggcggagaacgctcataatgtctgggccaaagac cgcatcaaacagggctggacctacggcatacaacaggatgtgaaaagcaagcgtaaccct cgtctggtgccatatgctttactcgatgagcgcaccaagaagtcgaaccgtgacagcctc agggaggccatacgcactctcattggatacggatacaacatcgagccgcctgaccaagat gctggtcatgtggtggagcggttgagtattgataagatccggttcttccgtgtggagcgg acatacgcagtgaagaccggtaaatggtattttgagtttgaggcggtgacgggaggagac atgagggtcgggtgggctcgacccggctgtaaacctgatgtagaactcggtacagatgat caggcgtacgtgtttgatggttatcggggtcatcggctccacatgggcagccgtctgttt ggccgctgttggcacgctggtgacgtggttggctgtatgatcaacatggaggacaaatca atgatcttcaccctcaacggagaaatcctgatcactaacaagggctctgaactctgtttc gctgactttgacagtaatgatggtttcatccccgtgtgtagtttgggtctgtgtcaggtt ggtcgtatgaatctcggtaaagacgccagcacgtttaaatactacaccatgtgtggactg caggagggctttgaaccatttgccgtcaacatgaatcgtgaggtcaccatgtggtttagt aaacgtctgccgaccttcttcaacgtgccaaaagatcacaagcacatagcggtcaccaga atcgacgggactatcgacagcccaccgtgtctgaaggtctcccataagatgtttggcact cagaacagtaacgctgacatggtgttctgcagattgagtatgcccgtcgagtttcactcc agcttcaagagcagcatctacgctcacgtgaacggagtgcatgaggaggaaccgctcaaa ctcaaacacaggtatcccgtgaagtcaatgaaacactcagatgaaggaaggagaactgac tacagcaacatcactacatattattattcagtgcgagtattcgctggtcaagatccatca tgcgtgtgggttggttgggtcacccctgactaccattactatagcaaccacttcaatctc ggcaagaaccgtactgtaacggttacccttggagacgagaggggccgcgtgcacgagagt gtgaagaggagtaactgttacatggtttggggtggtgatgtcaacagtgctgctcattcc accagcaggagtaatgtggatctagagattggatgccttattgatttggcaacggggctg ttagctttcacagtcaatggcaaagaacttccgagctcatatcaggtggagcccagtact aaactctttcctgctgtgtttgtacggccaacgagttccagtctgttccagtttgaactg agcaaaatcaagaatgcgatgcccatttcctctgccatctttaagagtgagcacaagaat cctgttcctcaatgtccacctcgtctggacgtccagaccatcaattcagtgctgtggagc cgaatgccaaacacattcctgaaggtggagacgactcgcgtcagtgagagacacggatgg atggtgcagtgtctggagccgctacagatgctcgctgtacacattccagaggagaaccgg tgtgtggatattatggagttatctgaacaagaagacttgcgtaaattccactatcacaca ctgaaactctactgcgctctgtgtgcacacggaaacacgcgtgtagctcatgccctctgc agccatctcgaccaatcacagctcctgtacaccatcgacaaccaatacctgtcaggcatg cttcgtgagggcttctacaacgttctcatcagtgtgcacctggagacggcccgggccgct cgcctcatgatgaacaacgagttcatcgtccccatcaccgccgagacgcgcagcattcga ctctttcctgatgcgtccaaacggcaccagcctccaggcgtcggcctcagcacctccctc aaacccagactcaactttgctccaccctgtttcataagcaccaaacgtgaccagcacctg tacagtcctgaagtcccattggacattctgaaggagaaggccatcagcatgctgacggag gcggtgcagggtggaggggatcacattagagaccctgtcggtgggagtgtggagtatcag ttcgtgcccattctacggctcattagcacgctgctgacgatggccgtcctgaccagcgat gacgtgcacaagatcttactgctcattgagcccaatgtgtttggagaacagatggttgaa ggactgagagatgcgacaatgaaagaaggtctgactggagccgaagagaaagctgtggaa gcaggagaggaagaagctaaagacagtaaagttctgatgaagggactgctggagaagaaa ctaccagagtctgttaaacgacagatgtgtgaactcctgcattatttctgtgactgtgag ttgagacatcggattgaagccatcgtgtcgttctctgatagtttcgtctcaaagctgcag tacaaccagaagtttcgttataatgagctgatgctcgctttgaacatgtctgctgccgtc actgccaaaaagaccaaagagtttcgctcgccgccgcaggaacagattaacatgctgttg aactttaatatgggtgaagattgtccgtgcccaggagacatacaggaagaactgtatgac tttcacagcgaactgcgactgcactgcggagttccagtggaggaggacgaggaagatctg gactcatccattaaaggtcgactgctcgctctcgtctataagatcaaaggtcaaccacag aaatctgaaacacagcccacagagaaagagcagaccgctccctcgaatctgaaggagttg atctctcagacgatggtgagctgggctcaggagactcacattcaggacccagagctggtg cgagtgatgttcagtctgctcaggagacagtacgacagcatcggcgagctgctccgggcc atgaggaaaacctacaccatcagcgccggctctgtacaagacaccatccacctgctcgca tcgctgggacagatccgatcgctgctcagtgtccgcatgggcaaagaggaggagcaactc atgattgacggcctgggtgacatcatgaataataaagtgttctaccagcatccaaacctc atgagagttctggggatgcacgagaccgtcatggaggtgatggtgaatgtactgggagga ggaaaatcacaggaaattgcttttcctaaaatggtggcgagctgctgtcgcttcctgtgt tacttctgtcgaatcagtcgtcagaatcagaaggccatgtttgatcatctgagttatctg ctggagaacagcagtgttggactggcgtctccgtccatgagaggttcgacacctttagat gttgctgcttcatctgtgatggataataacggtctggctcttgcgctggaggaacccgac ctggacaaggttgtgacgtatctggcgggttgtggactgcagagttgtcccatgctcata gctaaaggatatccagatatcggctggaaccctattgagggagaacgatacctctccttc ctgcgattcgctgtgtttgtcaacggtgagagtgtggaggaaaattccagtgtggtggtg aagcttctgattcgtcgaccggagtgttttggccccgccctgcgaggagaggggggaaac gggctgcttgcggccatgaaggaagctattaagatctcagagaacccatcgctggatctg cccagtacaggcccgggtcacgcttcagacgtatccactgagggtgaggaggaagaggaa gtggttcacatgggaaatgcgattttgtccttctactcggctctgatcgatctgttaggc cgttgtgctcctgagatgcacttgatcaataagggtaaaggtgaagctctgaggattcgt gccatcctaaggtctctcgtaccaactgaggatctggttggcatcattagtattcctctg aagatgccggtgctcaataaagatggcagtgtgacggagcccgacgtgtctgccactttc tgcccggaccacaaggcccctatggtgctgtttttggaccgtgtttatggtatagaggat cagagcttccttttgcatctgttagaggtcggcttcctgcctgaccttagagcatccgcc tcactggacacggaagctctccggacgactgaaacggctctggcgatgaatcggtacatt ggttctgccatgttgcctctgctcacccgctgtgcccctcacttctctggcacagagcat cacgccatgctcatcgactcgactctctacaccatctacagactgtccaagggctgttca ctcaccaaagcccagagagacgctatagaggagtgtttactcgccgtctgcaagtacctg agaccgtccatgttgcagcatcttctgcgtcggctggtgtttgatgtgccgctgttatcg gaatactgtaagatgccactgaagttgttgacgaatcattacgagcagaactggaagtat tactgtctgccctcgggatggggcagttacggtctggcgtctgaggaagaacttctgctc accaagaaaatcttctggggcatctttgattcgctctctcaaaagaagtatgaacaggag ctgtttaaaatggccatgccgtgtctgagtgccattgctggagctcttccgccggactat atcgactcgtctctcagcaccacactggagaaaccggtgtctgtagacgcacagggaaac ttcgagcccaaacccattaacacggccaacatctgtctgcctgaaaaactggaacacatt gcaaacaaatatgcagaacattcccatgagaaatggtcctctgagaaggtgattctgggc tggaaatatggagagaatattgatgaaaaagccaaaacgcactcaatgctcagatcatac aaatcactcacagagaaggagaaagaggtttatcgctggacggtgcgtgagtcattgaag agcatgttagcgatgggttggagtatcgacagaactaaagaaggagaatccatgtttcag cagagagagattgagaagatgcggcgaatatcacaagcgtctcagggtaacagcttcagt ccagctccactagacatgagcaacgtcctgctgtcaagagaacttcagtcgatggttgaa gttgtggctgaaaactatcacaacatctgggcaaagaaaaagaagagtgagctgggaaca agaggtggaggaactcatcctctgctggtgccgtatgacacactcacagctaaagagaaa gccaaagatcgagagaaagctcaagacctgttcagatttctgcagattaatggatacgcc atcaccagaggtttgaaggatatggaacaagattcttcctccatggagaaacgcttcgcc tataaattcctgaagaagttgctgaaatatgtcgactcagctcaggagtttattgctcac ctcgaggcgatggccaccagtggaaagaacgacaaatcaccacatgaacaagaaatcaag ttctttgcgaaggtgctcctccccctcattgatcagtactttaaaaaccactccctctac ttcctgtcatcgcccactaagaatctgagcagcagtggatacgcatctaataaagagaaa gagatggtcaccagtctgttctgtaagctggccgctctggttagacacaggatttctctc tttggaagtgactccaccactattgtcagctgtctgcatattctcgcacacacactggac accaggacggttatgaagtccgcttctgagctggttaaagccggtttgaggacgttcttt gagaatgccgctgaagatctggagaagaccctggagaacctgaagctggggaagttcact cactctcgcagtcagatgaagggagtgtcacagaacatcaactacacgaccgtcgctctg ctgcccatcctcacggcactgtttgaacacatcactgaacatcagtttggatcagacctg ctgttggatgatgtccaggtgtcgtgttatcgaatcctgaccagtttgtactcgctgggg acgggaaaaaatatctatgtggagaggcagcttccagcgttgggcgagtgtttggcgact cttgcgggtgcgatgcccgtggcgtttttagaaccgcagttgaacaaacacaacacctgt tctgtgttcaacaccaagacatctcgtgaacgagccattctaggaatgccggagtgtgtg gatgagatgtgtcctgatatgcctcgtctggatggtttgatgaaggacattaatgacatg tcagagtcgggcgctagatacactgagatgccgcacgtcattgaggtggtgctgcccatg ctgtgtaactatctgtcgtactggtgggagcgtggaccagagaaccgctgtgagagcgcc gccgtctgtagcaccaccgtcacgtctgaacatctgagtgtcatcctcgggaacatctta aagatcctcaacagtaatctgggcatcgacgaggcatcctggatgaaacgcatcgcagtt tatgctcagccgatcatcagtaaagcacgagcagacctgctgaagactcacttcctaccc acactggagaaactgaagaagaagacggtgaaagtggtgatggaggaggagcttctgaaa gccgatggcaaaggcgacacccaggaggcggagcttctcattctcgatgagtttgcggtg ctgtgcagagatctgtacgcattctatccgatgcttatccgctacgtagacaacaacagg tctcgttggctgaaggaacccgacgccgattcaaacgaactcttcaggatggtggcagag attttcatcctgtggtgcaaatcacacaatttcaaaagggaagagcagaactttgttgtt cagaatgaaattaataatctgtcctttctcaccggtgacagtaaaaccaaactggcaaag tcgtttcttccgaagtctggaggtcaggatcaggagaggaaacacaagaagcgtcgtgga gatttttactccatccaaacgtctctgatcgtctcagctctgaagaagatgctgcccatc ggtctaaacatgtgcacgcccggcgatcaggagctcatcctactcgccaagacacgatac agcctgaaagacacggatgacgaagtgaagcagcatatcagacagaacctgcacctgcag gaaaagtctgaggaccccgctgttcgctggcagctcaatctttacaaggacgtgatcgtg aagaccgaggaaacttcagatccagagagaacggttgagagaatccagagtatctcagcc gctgtgtttcatctggagcaggttgagcagccgttaagatctaagaagtgtgtttggcag aagttgttgtctaaacagcgtaagcgagctgtggtggcgtgtttcagaatggcaccactt tataacctgcccaggcatcgctcgattaacctgttcctcacgggttatcagagactgtgg atagaagcagagatgtactcgtttgaggagaaactagtgcaggatctcgcaaagacacag ccgaagtctgatgaagaggaggaggagatcacagacactcaaccagaccctcttcatcaa ctcatcctgcacttcagtcataacgcactgacagaacgcagttgtttggaagaggatcag ctgtacatcgcttatgcagatatgatggcaaagagttgtgctgaaaatgaggaagaggat gaggaaggcaaagagaaaacatttgaggagaaggagatggagaagcagaagactctgtat cagcaagcgagacttcatgacagaggagcagcagagatgatcttacagatgatcagtgcc agtaaaggtggtttgggttcaatggtgacgttcacgctgaaactcggcatctccattctc aacggtggaaacactctagttcagcagaaaatgttggactatctcaaggagaaacgagac gtgggatttttcaagagcttgtcaggactgatgcagtcgtgcagtgttttggatctgaac gcgtttgagcgtcagaataaagccgagggtttgggaatggtgactgaagagggctccatc aacgtgagggagcgcggttctaaagttcttcagaatgacgagttcaccaaagatctgttc aggtttctgcagctcttgtgtgagggtcacaataacgatttccagaactttctgagaaca cagaccggaaacacgaccacggtgaatatcatcatcagcaccgtggactatctgctccga ctgcaggagtccatcagtgatttttactggtattactctggtaaagatgtcatggatgaa gccggtcagcgtaatttctctaaagctctcgctgtggccaaacagatcttcaactcactc actgaatacattcagggtccgtgtattgggaatcagcagagtttagctcacagtagactc tgggatgcagttgttggatttctgcatgtttttgccaacatgcaaatgaagctgtcacag gactccagtcagatcgagctgttgaaggagttgatggatctacagaaggacatgatcgtc atgatgctttctctgctggaaggaaatgttgttaacgggactatcggcaaacagatggtg gatactctagtggagtcctccaacaatgttgagatgatcctgaagttctttgacatgttc ctaaaactgaaagatctaaccacctctgaaaacttcaaagaacacgatcccgacaggaaa ggagttatctccaagaaagagttccagaagtccatggagaaccagaaacagtactcacaa tctgagattgagtttctgctgtcctgcgctgaggccgacgagaatgacatgttcaattat gaggagtttgtgaaacgcttccacgaacccgcgaaggacatcggcttcaacgtggcggtt ctgctcaccaacctatcagagcacatgcctcacgattcccgtctcgccaccttcctgaac ttagcagagagcgtcctgaactactttgagcccttcctgggccgcatcgagatcattggc ggcgcgaagagaatcgagcgagtctactttgagatcagcgagtccagcagaacccaatgg gagaaaccgcaggtcaaagagtccaaacggcagttcatctttgatgtcgtcaacgagggc ggagaatccgagaagatggagctgtttgtgaacttctgcgaggacaccatctttgagatg cagttggcgtctctgatctctgagccggatgctgccgagagacctgaggatgatgaagat gaagatgctcagagtgtggctgagaatctagaggaggaagaggaagatggtgcactggag tcttcctcagcattcactctggcctgtgtctccatgaggaagagtctggccaacctccgg cagatgttgaccctcaagagcatgaagaggcagtacaggaggttgaggaagatgagcgtg agggaaatgatacgagggtttttctactttttctggatgatcttcaccggtatgttccgc ttcttctacaacctgatgtgggggttcttccacatcctgtggtccaccttgtttggtgga ggtctcgtggaaggagctaaaaacatgaaggtgacggatattctgggcaacatgcctgat cccacacagtttgggatccatggagacgttctggagattgagaagctggaatactgtgac atgtcttcagtagccgagctcagacatatcgcagccggagagcagactgagatggacctc atgtcagaactcatgaacattcatcccaggagagaaggaggcaaacacgggatggagccg ggtctcggagacgtgtcagaggtggttggagaggacactccttctttagccagcgctgta catcagaagaaagctcaggaagcggccactaaacaagcatccgagactgaaactaaatgt gaatccgagaaggcagatatggaggatggagagaagaaagaccaggacaagagtaaagag gaagtgctcaaagacccgctgtcaaaggaagacaagaagccaatgaagaaaagacgtgga cagaggaaagagccggccgaggcgttcatggcatcatttttcgccggtctggatgtctat cagactaaaatgctgaattatctggccagaaacttttacaacctgcgtttcctcgctctg tttgtggcgtttgccatcaacttcatcctgctcttctacaaggtgaccggtgaggactct gatgatctggacccgtggactcgtcgagaggaagatgatgatgaaggcgttgtggagtat tttgttcttcaggagagcaccggttacatggcaccgactctccgattcctcgccgtcatg cacacgctcatctcgttcctctgtgtggtgggatattattatctgaaggtgcctttggtg gtttttaagcgtgagaaggaaatcgctcgtaagctggagtttgatggtttgtacatcact gaacaaccgtctgatgatgacattaaaggacagtgggacagactcgtcatcaacacacca tctttccccaacaactactgggacaaatttgtcaaacgcaaggtcataaataaatatgga gatctttacggtgccgagcggatcgctgaactgttgggtttggataaaagtgctctggac ttcaacccaactgaagagacggtcattaaagatgcttcactgctctcctggttgagttcc attgacacaaagtatcacatctggaaaatgggcgtcgtgtttacagataattctttcctg tatctggtctggtacaccaccatgtctatactgggacactataataatttcttctttgct gcccatctgttggacatcgccatgggcttcaaaaccctgaggaccatcctctcctccgtc acacacaacggcaaacagctggtgttgacggtcgggctgctcgctgtggtcgtgtatctc tacactgtcgtggcgttcaacttcttccgcaagttctacaacaagagcgccgacgaggac gagcctgatatgaagtgtgatgatatgatgacttgttatctgtttcacatgtatgtgggc gtgcgagctggtggtggtatcggtgatgaaatcgacgacccagcgggtgacccgtatgaa ctctaccggattctgttcgacatcaccttcttcttctttgtcattgtgattctgctggcc atcatacaaggtttgatcattgatgcttttggagagctgagagaccaacaggaacaagtc aaagaagacatggagactaaatgtttcatctgtggtattggtaatgattatttcgacacg acgccgcacggctttgaaagtcacacgttacaagagcacaacctcgcaaactacctattc ttcttgatgtacctgatcaacaaagatgaaactgaacacaccggtcaggagtcgtacgtg tggaagatgtatcaggagagatgttgggatttcttcccagctggtgattgtttccgtaag cagtacgaagaccagctgggttag

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