Massilia sp. WG5: AM586_05755
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Entry
AM586_05755 CDS
T04122
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
masw
Massilia sp. WG5
Pathway
masw00300
Lysine biosynthesis
masw00550
Peptidoglycan biosynthesis
masw01100
Metabolic pathways
masw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
masw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AM586_05755
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AM586_05755
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AM586_05755
Enzymes [BR:
masw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AM586_05755
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ALK95862
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Position
4454862..4456232
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AA seq
456 aa
AA seq
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MRGSLAQLTASIEGARMTRDASFEGVSTDSRSAPAGALFVALRGETFDAHDFLDQVAARK
VAAVVVEKLPEDFPLPALVVPDTLAALGRIGNAWRSQFAIPVIGVTGSNGKTTVKEMIAA
ILAASVGEEARLATQGNLNNEIGVPLTVMRLTGAHRAAVVELGMNHPGEIARLAAIAAPT
VALVNNAQREHQEFMHTVEAVARENGSVLQALPSDGVAVFPGDDEYTALWRGLAGDRATL
TFGLSEACDVRATYTPNAFGSELQVTAPQGQFNIKLSAAGEHNVRNALAACACALAAGIS
RGAIVRGLEAFAPVSGRLQRKQAVNGATVIDDSYNANPDSVRAAIDVLAQANAPRILVLG
DMGEVGTQGPQFHEEIGAYAASRGIDTVLVTGALARHMTGAGAQHFEQFDDLLAALDKQL
GSKSDATVLVKGSRFMKMERAVQHLVQSQNTGKDSH
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgcgcggttcgctcgcacaattgaccgcttcgatcgaaggcgcgcgcatgacgcgcgac
gcctccttcgaaggcgtgtcgaccgacagccgttcggccccggccggcgcgctgttcgtc
gcgctgcgcggcgaaaccttcgatgcccacgacttcctcgaccaggtcgccgccaggaag
gtggcggccgtggtggtggagaagctgccggaagacttcccgctgccggccctggtggtg
ccggacacgctggcggcgctgggccgcatcggcaatgcctggcgcagccagttcgcgatt
cccgtgatcggcgtcaccggcagcaacggcaagaccacggtcaaggaaatgatcgcggcg
atcctggccgccagcgtcggcgaggaagcgcgcctggccacccagggcaatctgaacaac
gagatcggcgtgccgctgaccgtgatgcgcctgaccggcgcgcaccgcgccgccgtggtc
gaactgggcatgaaccatccgggcgagatcgcccgcctggccgccatcgcggccccgacc
gtcgccctggtcaacaacgcccagcgcgagcaccaggagttcatgcacaccgtggaagcg
gtggcgcgcgagaacggctcggtgctgcaggcgctgccttcggacggcgtcgccgtattc
cccggcgatgacgagtacaccgcgctgtggcgcgggctggcaggggatcgtgcgacgctg
actttcggcctgtccgaagcctgcgacgtgcgcgcgacctacacgccgaacgcctttggc
agcgagctgcaggtcactgcgccgcagggacagttcaacatcaaactttccgccgcgggc
gagcacaacgtgcgcaacgccctggcggcctgcgcctgcgcgctggccgccggcatctcc
cggggcgccatcgtgcgcggcctggaagctttcgcgcccgtcagcggccgcctgcaacgc
aagcaggccgtcaacggcgccaccgtgatcgacgacagctacaacgccaacccggattcg
gtgcgcgccgccatcgacgtgctcgcgcaggcgaacgcgccgcgcatcctggtgctgggc
gacatgggcgaggtcggcacgcagggaccgcagttccacgaagagatcggcgcctacgca
gcaagccgcggcatcgataccgtgctcgtcaccggcgcattggcgcgccacatgacgggc
gcgggagcgcaacactttgagcagttcgacgatttattggcagcactggataagcaactg
ggcagcaaatccgacgcaactgtgttggtgaagggctcgcgcttcatgaagatggaacgc
gcggtccagcatctcgttcaatcacaaaacactggcaaggattctcactaa
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