Micromonospora aurantiaca: Micau_5640
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Entry
Micau_5640 CDS
T01296
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mau
Micromonospora aurantiaca
Pathway
mau00860
Porphyrin metabolism
mau01100
Metabolic pathways
mau01110
Biosynthesis of secondary metabolites
mau01120
Microbial metabolism in diverse environments
mau01240
Biosynthesis of cofactors
Module
mau_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mau_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mau00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Micau_5640
Enzymes [BR:
mau01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Micau_5640
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Micau_5640
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
PqqF-like_C_4
Motif
Other DBs
NCBI-ProteinID:
ADL49146
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Position
complement(6308993..6310573)
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AA seq
526 aa
AA seq
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MTRTRKPVGQIAFVGAGPGDPGLLTRRALDALVEADQVVYDRGVPESLLAHVRAQARPGA
EFSPAEGVPGDVAKVLISAARSGQNAVHLVAGDPFGHDSVVKEVQAVARTAAHFEVVPGV
GQAEGVATYAGVPLPGVRTAADVEDVTALDFEALATAVGRGSLALAVDAGDLAAVRDGLL
AAGVDGTTAVGVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTVGAAVTDRDKLSWWE
NRPLYGWKVLVPRTKEQAGVMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVDGR
YAWVIFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGDATAEAVRAFGIQPELIPSGEQ
SSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLTERGWEVDDVTAYRTVRAAPPP
AEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETATEFGLRVDVQ
PPHASVPDLVEALAAYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcacccgtaagcccgtaggccagatcgcattcgtcggggccggtcccggcgac
ccgggcctgctgacccgccgggcgctggacgccctggtcgaggccgaccaggtggtctac
gaccggggcgtacccgagtcgctcctggcgcacgtccgcgcccaggcccggccgggcgcc
gagttcagccccgccgagggcgtgccgggggacgtggcgaaggtgctgatctccgcggcc
cggtccgggcagaacgccgtgcacctggtcgccggtgacccgttcggccacgactcggtg
gtcaaggaggtgcaggcggtcgcgcgtaccgccgcgcacttcgaggtggtcccgggcgtc
ggccaggccgagggcgtggccacgtacgcgggtgtcccgctgccgggcgtacgcaccgcc
gccgacgtcgaggacgtcaccgcgctggacttcgaggcgctcgccaccgccgtcgggcgg
ggttcgctggcgctcgccgtggacgccggtgacctggccgccgtccgggacggcctgctg
gccgccggggtcgacggcaccacagcggtcggggtgaccggtgacggcaccggcgagacg
cagtacaccaccacgtcgacagtcgactccttcgtcgcggcggcgctcggcttcaccggc
cgggtggtgctcaccgtcggcgcggccgtcaccgaccgcgacaagctgagctggtgggag
aaccgcccgctgtacggctggaaggtgctggtgccccgcaccaaggagcaggccggcgtg
atgagtgcgcggctgcgcgcgtacggggcgatcccgtgcgaggtgccgaccatcgcggtc
gagccgccgcgtaccccggcgcagatggagcgggccgtgaagggcctggtcgacggccgg
tacgcctgggtcatcttcacctcggtgaacgcggtccgggcggtgtgggagaagttcgcc
gagcacggcctcgacgcccgccacttcggtggcgtgaagatcgcctgcatcggtgacgcc
accgccgaggcggtccgtgccttcggcatccagcccgagctgatcccctccggggagcag
tcctccgagggcctgctggccgagttctcgccgcacgacgagatcctcgacccggtcggc
cgggtgctgctgccgcgcgccgacatcgccaccgagaccctggccgccggcctgaccgag
cgcggctgggaggtcgacgacgtgaccgcgtaccggaccgtgcgcgcggcgccgccgccc
gccgagatccgcgacgcgatcaagtccggcgggttcgacgcggtgctgttcacctcgtcg
tccacagtgcggaacctcgtcggtatcgccgggaagccgcacgcgcggaccgttgttgca
gtgatcgggcccaagacggcggagaccgccaccgagttcggcctgcgcgtcgacgtgcag
ccgccgcacgcctcggtgcccgacctggtggaggcgctcgccgcctacgccgtcgagctg
cgggagaagctcgccgccatgccggcgaagcagcgccggggctcgaaggtgcagggcccg
accgccctgcggttccgctga
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