Mesocricetus auratus (golden hamster): 101828280
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Entry
101828280 CDS
T08306
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
maua
Mesocricetus auratus (golden hamster)
Pathway
maua00230
Purine metabolism
maua00670
One carbon pool by folate
maua01100
Metabolic pathways
maua01523
Antifolate resistance
Module
maua_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
maua00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101828280 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101828280 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101828280 (Gart)
Enzymes [BR:
maua01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
101828280 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
101828280 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
101828280 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_4
RimK
LUD_dom
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
101828280
NCBI-ProteinID:
XP_005073868
UniProt:
A0A1U8BZW0
LinkDB
All DBs
Position
Unknown
AA seq
1008 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACCGKISNAAVFVSDHAVLAQ
FCKDEKIELVVVGPEAPLAAGVVEDLTRAGVRCFGPTAQAAQLESSKKFAKEFMDRHGIP
TAQWRAFTSPEDACSFIMSADFPALVVKASGLAAGKGVIVAESKEEACRAVQEIMREKSF
GAAGETVVVEEFLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDQGPNTGGMGAYCPTP
QVPKDLLLKIKTTILQRTVDGMRQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGMLNTCLPVWLENHTAITVVMASKGYPGAYAKGVEITGFPEA
QALGLQVFHAGTALKEGRVVTSGGRVLTVTAVRENLVSALEEAKKGLAAIKFEGAVYRKD
IGFRAVAFLQRPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCNVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCSKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLRTTEAVVAGIAGACGQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
QLERITEGDVVVGVASSGLHSNGFSLVRKIVARSSLQYSSPAPDGCGDQTLGDLLLTPTK
IYSHSLLPIIRSGRVKALAHITGGGLLENIPRVLPQKLGVDLDACTWRIPKIFSWLQREG
QLSEEEMARTFNCGIGAALVVSKDQTDQILHDIGQRREEAWVIGNVVACPEGSPRVRVKN
LTEALQMNGAVVSNGFLSHLPAQQKSRVAVLISGTGSNLQALIDSTRDPKSSTHIVVVIS
NKAGVTGLDKAEKAGIPTRVINHKLYKNRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGP
FVKKWDGKMLNVHPSLLPSFKGSNAHEQVLEAGVRITGCTVHFVAEDVDAGQIILQEAVP
VKRGDTVATLSERVKVAEHKIFPEALQLVASGAVRLGEDGKICWITGQ
NT seq
3027 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagttcttgtgattggcagtggagggagggaacataccttggcctggaaa
ctagcacagtctcatcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
tgttgcggaaagatctcaaatgctgctgtcttcgtctctgatcacgctgtcctggctcag
ttctgcaaagatgaaaagattgagctcgtggttgttggaccagaggcccctctagctgca
ggagttgttgaggacctgacccgtgccggcgtacgatgctttggccccacagcacaagca
gcccagttagaatccagtaaaaagtttgccaaagagtttatggatcgacatggaatccca
actgcgcagtggagagccttcaccagtcctgaagatgcctgcagctttattatgagcgca
gacttccctgctttggttgtgaaggccagtggccttgcagctgggaaaggagtgattgtt
gcagagagcaaggaggaggcctgcagagctgtacaggagatcatgcgagaaaagtctttt
ggagcggctggagaaacagttgttgtggaagaatttctggaaggggaagaagtgtcttgt
ctatgtttcactgatgggaagacagtggccccaatgcccccagcacaggaccataagcga
ttgctggatggagatcagggccccaacacagggggaatgggagcctattgcccaacaccc
caggttcctaaagatttgttactaaagattaaaaccactattcttcagagaacagtcgat
ggcatgcggcaggagggtgtgccctacacaggaattctctacgctggtataatgctgacc
aaagatggcccaaaagttttggagtttaattgccgttttggtgacccagaatgccaagta
atcctcccacttcttaaaagtgacctttatgaagtgatccagtccaccttggatggcatg
ctgaatacgtgtctgcctgtttggctagaaaaccacactgccataactgttgtcatggca
agtaaagggtaccccggagcctacgccaagggtgtggagataacagggtttccagaggcc
caggctttaggactgcaggtattccatgcaggcactgctcttaaagaaggcagagtggtg
accagtgggggcagagtcctcacagtgacagctgtccgggaaaatcttgtgtcagccctt
gaagaagccaagaaaggacttgctgctataaagtttgagggagcagtttacaggaaggac
attggcttccgtgctgtggccttcctccagcggcccaggggcctgacttacaaggattct
ggagttgacattgcagctggaaatatgctggttaagaaaattcagcctttagcaaaagcc
acctccagaccaggctgcaatgttgaccttggaggctttgctggtctttttgatttgaaa
gcagctggttttaaagatcctcttctggcctctggaacagatggtgttgggactaaactg
aagattgcccaactgtgcagcaagcatgacaccattggtcaggatctggtcgccatgtgt
gtaaatgacatcctagcacaaggagcagagcccctcttcttccttgattacttttcctgt
gggaaacttgacctcaggaccactgaagctgttgttgctggaattgctggcgcttgtgga
caagctggctgtgctctcctgggtggggagactgcagagatgcccgacatgtaccctcct
ggcgagtacgacctggccggctttgctgtgggtgcaatggagagggatcagaaactccct
cagctcgaaaggatcaccgaaggggatgtcgttgttggagtagcttcatctggtcttcac
agcaatgggtttagccttgtgaggaagatcgtagcgaggtcttccctccagtactcctct
ccagcgcctgatggatgtggtgaccagacactgggggacttacttctaactccaaccaag
atctacagccattcactgttgcctatcatacgctcgggacgtgtcaaagccttggctcac
atcactgggggtggactgctggaaaacatccccagagtcctccctcagaagcttggggta
gatttagatgcctgcacttggaggatccccaaaatcttctcatggttgcagcgggaagga
cagctctctgaagaagaaatggcgagaaccttcaactgtgggattggggctgccctggtg
gtgtctaaggaccagacagaccaaattctgcatgacattgggcagcgccgggaggaagcc
tgggtgataggcaatgtcgtggcctgtcctgaaggttctcctcgtgtcagagtcaagaat
ctgactgaagccttgcaaatgaatggggcagtggtgtcaaatggtttcctgagtcatctc
cctgcccagcagaagtcaagagtggctgtcttaatatctggaacaggatcgaacctccaa
gcactcatagacagcactcgggatccaaagagctccacacacattgtggttgtcatctcc
aacaaagctggggtcacgggcctagacaaagcagaaaaggctggcattcccaccagagta
attaatcataaattatataaaaatcgtgttgaatttgacaatgctgttgaccacgtccta
gaagagttctctgtagacatagtctgtcttgcaggattcatgagaattctctctggccct
tttgtcaaaaaatgggatgggaaaatgctcaacgtccacccatccttgctcccgtccttt
aagggctcaaacgctcatgagcaagtcctggaagccggagtcaggattaccggctgtacc
gtacactttgtagctgaagatgtagatgccggacaaatcatcctacaagaagctgtccct
gtgaaaaggggtgacactgttgcaactttgtctgaaagagtcaaagtagcagaacataaa
atctttccggaagccctgcagctggtggccagtggggccgtgcggcttggagaagacggc
aagatctgctggatcacaggacagtaa
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