Mesocricetus auratus (golden hamster): 101831170
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Entry
101831170 CDS
T08306
Symbol
Cyp17a1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase precursor
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
maua
Mesocricetus auratus (golden hamster)
Pathway
maua00140
Steroid hormone biosynthesis
maua01100
Metabolic pathways
maua04913
Ovarian steroidogenesis
maua04917
Prolactin signaling pathway
maua04927
Cortisol synthesis and secretion
maua04934
Cushing syndrome
Module
maua_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
maua_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
maua_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
maua00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
101831170 (Cyp17a1)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101831170 (Cyp17a1)
04917 Prolactin signaling pathway
101831170 (Cyp17a1)
04927 Cortisol synthesis and secretion
101831170 (Cyp17a1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101831170 (Cyp17a1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
maua00199
]
101831170 (Cyp17a1)
Enzymes [BR:
maua01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
101831170 (Cyp17a1)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
101831170 (Cyp17a1)
Cytochrome P450 [BR:
maua00199
]
Cytochrome P450, animal type
CYP17 family
101831170 (Cyp17a1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
101831170
NCBI-ProteinID:
NP_001268860
UniProt:
P70687
A0A1U7Q8W9
LinkDB
All DBs
AA seq
511 aa
AA seq
DB search
MWELVALLLLTLAYFFWSKSKTCGAKSPKSLPFLPLVGSLPFIPRHGHPHVNFFKLQEKY
GPIYSLRLGSTTTVIIGQYQLAKEVLVKKGKEFSGRPHMVTLGLLSDQGKGIAFADSGGS
WQLHRKLALSSFALFRDGNQKLEKIICQKASSLCDFLLTHNEESIDLSEPIFNSITNIIC
IICFGISYENRDPILATIKSFTEGILNSLGNDHLVDIFPWLTIFPNKTVDMIKKNVKIRD
EVLSGILEKCKEKFNSDSISSLMDLLIQAKTNADNNNTSEGQGSNAFSDMHILATIADIF
GAGIETTASVLSWIIAFLLHNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREV
LRIRPVAPMLIPHRANSDMSIGEFSIPKFTPVIINLWALHHSEKEWDQPDRFMPERFLDP
TGSHLITPSLSYLPFGAGARSCIGEVLARQELFLFMAHLLQRFDLDVPDDEQPPCLKGNA
NVVFLIDPFKVKITVRQAWKDAQAEVNTWRP
NT seq
1536 nt
NT seq
+upstream
nt +downstream
nt
atgtgggaacttgtggctctcctgctgctcaccctggcctatttcttttggtccaagtca
aagacgtgtggtgccaagtcgcccaagagcctcccattcctgccgcttgtgggcagcctg
ccgtttatccccagacatggccatccgcatgtcaacttcttcaagctgcaggaaaaatat
ggtcccatctattctcttcgtctgggttccacaacgacagtgatcatcggccaatatcag
ttggccaaggaagtgcttgtcaagaaaggaaaagaattctctggtcggccccacatggtg
actctaggtctcttgtcggaccaaggaaaaggcatcgccttcgctgactctggtggctcc
tggcagctgcaccggaagctggcgctcagcagctttgccctgttcagggacggtaaccag
aaactagagaagatcatatgtcagaaagccagctcgttgtgtgacttcctgctcacccac
aatgaggagtccatagatctttccgaacctatcttcaactcaataaccaacatcatctgt
atcatctgcttcggcatctcttatgagaacagggatccgatactggccaccattaagagc
tttacagaaggcatcctgaacagcctgggcaacgatcatctggtggacatattcccttgg
ttgacgatttttcccaataaaactgtggacatgataaagaaaaatgttaaaattcgagat
gaagttctaagtggaatattagaaaaatgcaaggagaaattcaacagtgactccatctcc
agcttgatggaccttctaatacaagccaagacaaatgcggacaacaacaacaccagtgaa
ggccagggttcaaatgcattttcagacatgcatatccttgccacaatagcagacatcttt
ggcgctggcatagaaaccaccgcctctgtgttgagttggattattgcttttctgctgcat
aatcctgaagtgaagaagaagatccaaaaggagatcgaccagaatataggtttcagtcgc
acgccaactttcaacgaccggaatcacctcctaatgctggaggccactatccgagaagtg
cttcgtatcaggcctgtggcccccatgctcatcccccacagggcaaacagtgacatgagc
attggtgagtttagcatccccaagttcacacccgtgatcatcaatttgtgggcactgcat
catagtgagaaggaatgggaccagccagatcggttcatgcctgagcgcttcctagaccca
acgggaagccatcttatcacaccctcattaagctacctgccctttggagctggagcccgc
tcctgcatcggagaggttctggcccgccaggagctcttcctctttatggctcacctgctg
cagaggtttgacctcgatgtcccagatgatgagcagccgccctgcctgaagggtaacgcc
aacgtggtctttttgatagaccccttcaaagtgaagatcacagtgcgccaggcatggaag
gatgcccaggcagaggttaacacctggaggccataa
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