Mesocricetus auratus (golden hamster): 101838351
Help
Entry
101838351 CDS
T08306
Symbol
Top2b
Name
(RefSeq) DNA topoisomerase 2-beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
maua
Mesocricetus auratus (golden hamster)
Pathway
maua01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
maua00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101838351 (Top2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
maua03032
]
101838351 (Top2b)
03036 Chromosome and associated proteins [BR:
maua03036
]
101838351 (Top2b)
Enzymes [BR:
maua01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101838351 (Top2b)
DNA replication proteins [BR:
maua03032
]
Eukaryotic type
DNA Topoisomerases
101838351 (Top2b)
Chromosome and associated proteins [BR:
maua03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101838351 (Top2b)
Centrosome formation proteins
Centriole proteins
101838351 (Top2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
Motif
Other DBs
NCBI-GeneID:
101838351
NCBI-ProteinID:
XP_005081038
UniProt:
A0A1U7R7C6
LinkDB
All DBs
Position
Unknown
AA seq
1612 aa
AA seq
DB search
MAKSSLAGADGALTWVNNSAKKEELETSNKNDSSKKLSVERVYQKKTQLEHILLRPDTYI
GSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDP
ESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCN
IFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLAKFKMEKL
DKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHE
LANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSV
KPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESI
LNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVS
GLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTL
RYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYS
IPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITL
AFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDN
ERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNL
AQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYD
DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPN
YKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTP
ALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKK
YETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKK
DLIQMLVQRGYESDPVRAWKEAQEKAAEEEDTQNQHDDSSSDSGTPSGPDFNYILNMSLW
SLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMS
GKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDPDTTVVKV
EFDEEFSGTPVEGTGEETSTPSAPVNKGPKPKREKKEPGTRVRKTPTSSGKPNAKKVKKR
NPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEEEDADDDDDNNDLE
ELKVKASPVTNDGEDEFVPSDGLDKDEYAFSPGKSKATPEKSSHDKKSQDFGNLFSFPSY
SQKSEDDSAKFDSNEEDTASVFAPSFGLKQTDKVPSKTVAAKKGKPPSDTAPKAKRAPKQ
KKVVETVNSDSDSEFGVPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKPSKTASKKPK
KTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4839 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtccagcctcgcgggtgctgatggggcgctgacctgggtgaacaattctgca
aaaaaggaagagttggaaacctcaaacaaaaatgattcttcaaagaagttgtctgttgag
agagtgtaccagaagaagacccaacttgaacatattctccttcgtcctgatacatacatt
ggatcagtagaaccattgacccagttaatgtgggtgtatgatgaagatgtaggaatgaac
tgcagagaggttacctttgttccaggcttatacaagatctttgatgaaattttggtcaat
gccgctgacaataagcagagggacaagaacatgacctgtattaaggtttctattgatcct
gaatctaatattataagcatttggaataatgggaaaggcattccagtagtagaacacaaa
gtagagaaagtttatgttcctgctttaatctttggacagcttttaacatcgagtaattat
gatgatgatgagaaaaaagttacagggggccgtaatggttatggtgcaaaactttgtaat
atttttagtacaaagtttacagtagaaacggcttgcaaagaatacaaacatagttttaag
cagacgtggatgaataatatgatgaagacttctgaagccaaaattaaacattttgatggt
gaagattatacatgtataacattccaaccagatctagccaagtttaagatggaaaaactt
gacaaggatattgtggctctgatgactagaagagcatatgatttggctggctcatgtaaa
ggggtcaaggtcatgtttaatggaaagaagttgcctgtaaatggattccgcagctatgta
gacctttatgtgaaagacaaattggatgaaactggggtagcccttaaagttattcatgaa
cttgcaaatgaaagatgggatgtttgtcttaccttgagtgaaaaagggttccaacagatc
agctttgtgaatagtattgcaactacaaaaggtggtcggcatgtggattacgtagtagat
caagttgttggtaaactgatcgaagtagttaagaaaaagaacaaagctggtgtatctgtg
aagccatttcaagttaaaaaccatatatgggtttttattaattgtcttattgagaatcca
acctttgattctcaaactaaggaaaacatgactctgcagcccaaaagttttgggtccaaa
tgccaactgtcagaaaaattttttaaagcagcctctaattgtggcattgtagaaagcata
ttaaactgggtgaaatttaaggctcagactcagctgaataagaagtgttcatcagtaaaa
tacagtaagatcaaaggcattcccaaactggatgatgccaatgatgctggtggcaaacat
tccctggagtgtacattgatattaacagagggggactctgccaaatcgctagctgtatct
ggattaggtgtgattggaagggacagatatggagtcttcccactcaggggtaaaattctc
aatgtgcgagaagcgtctcataaacagattatggaaaatgcagaaataaacaatattatt
aagatagtgggcttacaatataagaaaagttatgatgatgcagaatctctgaaaacctta
cgttatggaaagattatgattatgactgatcaggatcaagatggttctcacatcaaaggc
cttctaatcaattttattcatcacaattggccatcacttctgaagcatggttttcttgaa
gaatttattactcccattgtaaaggcaagcaaaaataagcaggaactttccttttatagt
attcctgaatttgatgaatggaaaaaacatatagaaaaccagaaagcctggaaaataaaa
tactacaaaggattgggtaccagtacagctaaagaagcaaaggaatattttgccgatatg
gaaaggcatcgtattttgtttagatatgctggtcctgaagatgatgctgccattaccttg
gcatttagtaagaagaagattgatgacagaaaagaatggttaacaaactttatggaggat
cggagacagcgtaggttacatggcctaccagagcaatttttatatggaacagcaacaaag
catttgacatacaatgatttcatcaacaaggaattgattctcttctcaaattcagacaat
gagagatctataccgtcacttgtggatggcttcaaaccaggccaacgaaaagttttgttt
acctgtttcaagaggaatgataaacgtgaagtaaaagtcgcccagctggctggatctgtt
gctgaaatgtctgcttatcatcatggagaacaagcattgatgatgactattgtaaatttg
gctcagaattttgtgggcagtaacaacattaacttgcttcaacccattggtcagtttgga
acacggcttcatggtggcaaagatgctgcaagccctcgctatattttcacaatgttaagc
tctctggcaagactactttttccagctgtggatgataacttgcttaagttcctttatgat
gataatcagcgtgtagaacctgagtggtatatccccataatccctatggttttgattaat
ggtgcagagggcattgggactggatgggcttgtaaactgcctaactatgatgctagagaa
attgtgaacaatgtcagacggatgctagacggtttggaccctcatcccatgcttccaaac
tacaaaaacttcaaaggcaccatccaagaacttggtcagaaccagtatgctgtcagtggg
gagatatttgtggtggatagaaacacagtagagattacagaacttccagttagaacttgg
acacaggtatacaaggagcaggttctagaacctatgcttaatggaacagataaaacacca
gcattaatttcagattacaaagaatatcatactgatacaactgtgaaatttgtggtgaaa
atgacagaagaaaaacttgcacaagcagaagctgctggactgcataaagtttttaaactt
caaactactcttacctgtaattccatggtactctttgatcatatgggatgtctgaagaag
tatgaaactgtgcaagacattctgaaagaattctttgatttacgactaagttattatggt
ttacggaaggaatggcttgtaggaatgttgggagcagaatctacaaagcttaataatcaa
gcccgtttcattttagagaagatacaagggaaaattactattgagaataggtcaaagaaa
gatttgattcaaatgttagtccagagaggttatgaatctgacccagtgagagcgtggaaa
gaagcacaagaaaaggcagcagaagaggaagacacacaaaaccaacatgacgatagttcc
tctgactcaggaactccttcaggccctgattttaattatattttaaatatgtctctatgg
tctcttactaaagaaaaagttgaagaactcattaagcagagagatacaaaagggcgagaa
gttaatgatctcaaaaggaagtctccttcagatctttggaaagaagatttagcagcattt
gttgaagaactggataaagtggaagcacaagaacgagaagatattctggcaggaatgtct
ggaaaagcaataaaaggtaaagttggcaaaccgaaggtaaagaaacttcagctggaggag
acgatgccctcaccttatgggagaagaattgttcctgaaattactgctatgaaggcagat
gccagcagaaaattgctgaagaagaagaagggtgatcctgataccacagtagtgaaagta
gaatttgatgaagaatttagtggaacaccagtagaaggtacaggagaagagacatcaacc
ccatcagctcctgtaaataaaggtcccaagcccaaaagggagaaaaaggagcctggtacc
agggttagaaaaacacccacatcatctggtaaaccaaatgcaaagaaagtgaagaagcgg
aacccttggtcagatgatgagtccaagtcagagagtgatttggaagaaacagaacctgtt
gttattccaagagattctctgctcaggagagcagctgctgaaagaccgaagtacaccttt
gatttctcagaagaggaggaggaggatgctgatgatgatgatgacaataatgatttagaa
gaactgaaagttaaagcatcccccgtaacaaatgatggggaagatgaatttgttccttca
gatggcttagataaagatgaatatgctttttctcctggcaaatcaaaagctactccagaa
aaatcatcacatgacaaaaaaagtcaggattttgggaatctcttttcatttccttcatat
tctcagaagtcagaagatgattcagctaaatttgacagtaatgaagaagatactgcttct
gtttttgcaccatcatttggtctgaagcaaacagataaagttccaagtaaaacagttgct
gctaaaaagggtaaaccaccttcagatacagcccctaaggccaagagagcacctaaacag
aagaaagttgtagagactgtaaactctgactctgattctgaatttggcgttccaaagaag
actacaacaccaaaaggtaaaggccgaggggcaaagaaaaggaaagcatcaggctcagaa
aatgaaggtgactataatcctgggagaaaaccatctaaaacagccagcaagaaaccgaag
aaaacatcctttgatcaggattcagatgtagacatcttcccctcagacttcacttctgaa
ccacctgctctgccacggactggtcgggctaggaaagaagtaaaatattttgcagaatct
gacgaagaggaagatgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
