KEGG   Mesocricetus auratus (golden hamster): 101842633
Entry
101842633         CDS       T08306                                 
Symbol
Tbk1
Name
(RefSeq) LOW QUALITY PROTEIN: serine/threonine-protein kinase TBK1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
maua  Mesocricetus auratus (golden hamster)
Pathway
maua04014  Ras signaling pathway
maua04137  Mitophagy - animal
maua04140  Autophagy - animal
maua04620  Toll-like receptor signaling pathway
maua04621  NOD-like receptor signaling pathway
maua04622  RIG-I-like receptor signaling pathway
maua04623  Cytosolic DNA-sensing pathway
maua04657  IL-17 signaling pathway
maua04936  Alcoholic liver disease
maua05014  Amyotrophic lateral sclerosis
maua05022  Pathways of neurodegeneration - multiple diseases
maua05135  Yersinia infection
maua05160  Hepatitis C
maua05161  Hepatitis B
maua05162  Measles
maua05163  Human cytomegalovirus infection
maua05164  Influenza A
maua05165  Human papillomavirus infection
maua05167  Kaposi sarcoma-associated herpesvirus infection
maua05168  Herpes simplex virus 1 infection
maua05169  Epstein-Barr virus infection
maua05170  Human immunodeficiency virus 1 infection
maua05171  Coronavirus disease - COVID-19
maua05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:maua00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101842633 (Tbk1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101842633 (Tbk1)
   04137 Mitophagy - animal
    101842633 (Tbk1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101842633 (Tbk1)
   04621 NOD-like receptor signaling pathway
    101842633 (Tbk1)
   04622 RIG-I-like receptor signaling pathway
    101842633 (Tbk1)
   04623 Cytosolic DNA-sensing pathway
    101842633 (Tbk1)
   04657 IL-17 signaling pathway
    101842633 (Tbk1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101842633 (Tbk1)
   05161 Hepatitis B
    101842633 (Tbk1)
   05160 Hepatitis C
    101842633 (Tbk1)
   05171 Coronavirus disease - COVID-19
    101842633 (Tbk1)
   05164 Influenza A
    101842633 (Tbk1)
   05162 Measles
    101842633 (Tbk1)
   05168 Herpes simplex virus 1 infection
    101842633 (Tbk1)
   05163 Human cytomegalovirus infection
    101842633 (Tbk1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101842633 (Tbk1)
   05169 Epstein-Barr virus infection
    101842633 (Tbk1)
   05165 Human papillomavirus infection
    101842633 (Tbk1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101842633 (Tbk1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101842633 (Tbk1)
   05022 Pathways of neurodegeneration - multiple diseases
    101842633 (Tbk1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101842633 (Tbk1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101842633 (Tbk1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:maua01001]
    101842633 (Tbk1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:maua04131]
    101842633 (Tbk1)
Enzymes [BR:maua01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     101842633 (Tbk1)
Protein kinases [BR:maua01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   101842633 (Tbk1)
Membrane trafficking [BR:maua04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    101842633 (Tbk1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal ABC1 Kinase-like DUF713 ubiquitin
Other DBs
NCBI-GeneID: 101842633
NCBI-ProteinID: XP_005079846
UniProt: A0A1U7QV83
LinkDB
Position
Unknown
AA seq 729 aa
MQSTPNHLWLLSDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQTLLTPVLANILEADQEKCWGFDQFFA
ETSDVLHRMIIHVFSLQQMTAHKIYIHSYNTAAVFHELVYKQTKISSSNQELIYEGRRLV
LELGRLAQHFPKTTEENPIFVISREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAVTG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTQVVITLDFCIRNIEKTVK
VYEKLMKVNLEAAELGEISDIHTKLLRLSSSQGTIESSLQDINSRLSPGGLLADTWAHQE
GTHPRDRNVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLDTADEWMRKMHLLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMLAASSGVKHAMAPVYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGALTMD
GGLRSVDCL
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagtactcctaaccatctgtggctcttgtctgacatcttaggccagggggccact
gcaaatgtcttccgaggaagacataagaaaactggtgatttatatgctgtcaaagtattt
aataacataagcttccttcgcccagtggatgttcaaatgagagagtttgaagtgttaaaa
aaactcaatcacaaaaacattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccctgtgggagtttatacactgttttagaggag
ccatccaatgcctatggactaccggaatcagaatttttaatcgttttacgagatgtggtg
ggtggaatgaatcatctccgagagaatggcatagtgcaccgtgatatcaagccgggcaac
atcatgcgtgtcataggggaggatggacagtccgtgtacaaactcacagacttcggtgcc
gctagagagctagaggatgatgagcagtttgtgtctctgtatggcacagaagagtatttg
caccctgacatgtatgagagagcagtactaagaaaagatcatcagaagaaatatggggct
acagttgacctttggagtattggagtgacattttaccatgcagctactggatccctgccg
tttagaccatttgaagggcctcgtaggaataaagaagtgatgtataaaataatcactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
ggagacatgcctgtttcttgtagtctttctcggggccttcagacactgcttaccccagtc
cttgcaaacatccttgaagccgatcaagagaagtgctggggttttgaccagttctttgca
gagactagtgatgtacttcaccggatgataatccatgtgttctcactgcaacagatgaca
gcacataagatttacatccatagctacaatacggctgctgtgttccatgaactggtctat
aagcaaaccaaaatcagttcttcaaatcaagaacttatctacgaaggacgacgcttagtc
ctagagcttggaagactagcccagcattttcctaaaaccacagaggaaaatccgatcttt
gtcataagccgggaacctctaagtaccataggattgatatatgaaaaaatttccctacct
aaagtccatccacgttacgatttagatggtgatgctagtatggccaaggcagtgactggg
gttgtgtgttatgcctgtagaattgccagtaccctgctgctctatcaagagttaatgcgg
aaggggatacggtggctcattgaattggttaaggatgattacaatgaaactgttcacaag
aagacacaagttgtgatcacattggatttctgcatccgaaacattgagaagacggtgaaa
gtatatgaaaagttgatgaaagtcaacctagaagcagcagagttgggtgaaatttcagac
atacataccaaattgttgagactttccagttctcagggaaccatagaaagcagtcttcag
gacatcaacagcaggctgtctccaggggggcttttggctgacacctgggcgcatcaggaa
ggcacacacccaagagacagaaatgtggaaaaactacaagtcctgttaaattgcatcacg
gagatttactatcagttcaaaaaagacaaggcagaacgtagactagcttacaatgaagaa
cagatccacaaatttgataaacaaaaactgtattaccatgcaacaaaagcaatgacccac
ttcacagacgagtgcgttaaaaagtatgaagctttcctggatactgcggacgagtggatg
cggaaaatgcatcttctcaggaaacagctgttgtctctaaccaatcagtgctttgatatt
gaggaggaagtgtccaaataccaagactacactaatgagttacaagaaactctgcctcag
aagatgcttgcagcctccagtggtgtcaagcacgccatggccccggtctaccccagctct
aacactttagtggagatgactctcggtatgaagaaactgaaggaagagatggaaggcgtg
gttaaggagctggctgagaacaatcatattctagaacggttcggggctttaactatggac
ggtggcctccgcagcgtggactgtctttaa

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