Mesocricetus auratus (golden hamster): 101843653 Help Entry 101843653         CDS       T08306                                  Symbol Jak1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism maua  Mesocricetus auratus (golden hamster) Pathway maua01521   EGFR tyrosine kinase inhibitor resistance maua04151   PI3K-Akt signaling pathway maua04217   Necroptosis maua04380   Osteoclast differentiation maua04550   Signaling pathways regulating pluripotency of stem cells maua04620   Toll-like receptor signaling pathway maua04621   NOD-like receptor signaling pathway maua04630   JAK-STAT signaling pathway maua04658   Th1 and Th2 cell differentiation maua04659   Th17 cell differentiation maua05140   Leishmaniasis maua05145   Toxoplasmosis maua05152   Tuberculosis maua05160   Hepatitis C maua05161   Hepatitis B maua05162   Measles maua05163   Human cytomegalovirus infection maua05164   Influenza A maua05165   Human papillomavirus infection maua05166   Human T-cell leukemia virus 1 infection maua05167   Kaposi sarcoma-associated herpesvirus infection maua05168   Herpes simplex virus 1 infection maua05169   Epstein-Barr virus infection maua05171   Coronavirus disease - COVID-19 maua05200   Pathways in cancer maua05203   Viral carcinogenesis maua05212   Pancreatic cancer maua05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:maua00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101843653 (Jak1)    04151 PI3K-Akt signaling pathway     101843653 (Jak1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101843653 (Jak1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     101843653 (Jak1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101843653 (Jak1)    04621 NOD-like receptor signaling pathway     101843653 (Jak1)    04658 Th1 and Th2 cell differentiation     101843653 (Jak1)    04659 Th17 cell differentiation     101843653 (Jak1)   09158 Development and regeneration    04380 Osteoclast differentiation     101843653 (Jak1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101843653 (Jak1)    05203 Viral carcinogenesis     101843653 (Jak1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101843653 (Jak1)   09162 Cancer: specific types    05212 Pancreatic cancer     101843653 (Jak1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101843653 (Jak1)    05161 Hepatitis B     101843653 (Jak1)    05160 Hepatitis C     101843653 (Jak1)    05171 Coronavirus disease - COVID-19     101843653 (Jak1)    05164 Influenza A     101843653 (Jak1)    05162 Measles     101843653 (Jak1)    05168 Herpes simplex virus 1 infection     101843653 (Jak1)    05163 Human cytomegalovirus infection     101843653 (Jak1)    05167 Kaposi sarcoma-associated herpesvirus infection     101843653 (Jak1)    05169 Epstein-Barr virus infection     101843653 (Jak1)    05165 Human papillomavirus infection     101843653 (Jak1)   09171 Infectious disease: bacterial    05152 Tuberculosis     101843653 (Jak1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101843653 (Jak1)    05140 Leishmaniasis     101843653 (Jak1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101843653 (Jak1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:maua01001]     101843653 (Jak1) Enzymes [BR:maua01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      101843653 (Jak1) Protein kinases [BR:maua01001]  Non-receptor tyrosine kinases   JAK family [OT]    101843653 (Jak1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  101843653 NCBI-ProteinID:  XP_005086692 UniProt:  A0A1U7R5X2 LinkDB All DBs Position Unknown AA seq 1152 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSFKKTEVKQVVPEPGVEVTFYLLDREPLRLGNGEYTAEEL CIKAAQECNISPLCHNLFALYNESTKLWYAPNHIITVDDKLSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRLRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENELS RSHSNDSGNVLYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLEYKHKKDEEKNKLRE DWNNFSYFPEITHIVIKESVVSINKQDNKNMELKLSSHEEALSFVSLVDGYFRLTADAHH FLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTC FEKSEVLGGQKQFKNFQIEVQKGRYSLHGSVDHFPSLRDLMNHLKKQILRTDNISFVLKR CCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIIQGEHLGRGTRTHIYSGTL LDYKDDEGIAEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVE NIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLL AREGIDSEIGPFIKLSDPGIPVSVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTT LWEICYNGEIPLKDKTLVEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIM RDINKLEEQNPDIVSEKKPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTG EQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSG SLKEYLPKNKNKINLKQQLNYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDF GLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDF SPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTTF QNLIEGFEALLK NT seq 3459 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaacataaaagaggactgcaatgccatggcgttctgtgctaaaatgagg agcttcaagaagactgaggtgaagcaggtggtccctgagccaggagtggaagtgaccttc tatctgttggatagggagccactccgcctgggcaatggagaatacactgcggaggagctg tgcatcaaggccgcccaggagtgcaatatttctcctctttgtcacaacctcttcgccctg tacaatgagagcaccaagctctggtacgctccgaaccacatcatcactgtggacgacaag ctgtctctccggctccactaccgcatgaggttctactttaccaactggcatggaaccaat gacaatgagcagtctgtatggcggcattctccaaagaagcagaaaaatggatatgaaaag aaaaaggttccagaagcaaccccactccttgatgctagttcactggagtatttgtttgcg cagggacagtatgatttgatcaaatgtctggctcccattcgggaccccaagacggagcag gatggacatgacattgagaatgagtgcctggggatggctgttctggccatctcacactat gccatgatgaagaagatgcagttgccagaacttcccaaagacatcagctacaagcggtat atcccagaaacattgaataaatccatcagacagaggaaccttcttaccagactgagaata aataacgttttcaaggatttcctgaaggaatttaacaacaagaccatctgtgacagtagt gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tatggagctgaaatatttgagacgtctatgctactgatttcatcagaaaatgaattgagt cggtcccattcgaatgacagtggcaacgttctctatgaagtcatggtgactggaaatctt ggaatccagtggcggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaactg aagcggaaaaaactggaatataaacacaagaaggatgaggagaaaaacaaactccgggaa gattggaacaatttttcctatttccccgaaatcacccacattgtaataaaggagtctgta gtcagcattaacaagcaggacaataaaaacatggaactgaagctctcttctcacgaggag gccttgtcctttgtgtccctggtagatggctacttccggctcacagcagatgcccaccat ttcctctgcaccgatgtggctcccccactgattgtccacaatatacagaatggctgtcac ggtccaatctgcacagaatatgccatcaataagctgcgacaagaagggagtgaggagggg atgtatgtgctgaggtggagctgcactgactttgacaacatcctcatgaccgtcacctgc tttgaaaagtctgaggtgttgggtggccagaagcagttcaagaactttcagattgaggtg cagaagggccgctacagcttgcatggctctgtagaccacttccccagcctgagagacctc atgaaccaccttaagaagcagatactgcgcacagacaacataagctttgtactgaagcgc tgctgtcaaccgaagccccgagaaatctccaatctgctggtagccaccaagaaagcccag gagtggcagcctgtctaccccatgagccagctgagttttgatcggatccttaagaaagat attatacaaggtgagcacctcggcagaggcacaagaacacatatctactccggcaccctg ctggactacaaggatgatgaagggattgctgaagagaagaagataaaagtgatcctcaaa gtcctagaccccagccacagggacatttctctggctttctttgaggcagccagcatgatg agacaggtttcccacaaacacattgtgtatctctatggtgtctgtgtcagagatgtggaa aatatcatggtggaagagtttgtggaggggggaccattggatctcttcatgcaccggaaa agtgatgtacttacaaccccctggaagtttaaagttgccaaacaactggccagtgccctg agttacttggaagataaagacctggtccatggaaatgtgtgcactaaaaaccttctctta gcccgtgaaggcattgacagtgagattggcccattcatcaagcttagtgatcctggcatc ccggtctctgtgctgtccaggcaagagtgcatagagcgaatcccctggattgctcctgag tgtgttgaagactccaagaacctgagcgtggctgctgacaagtggagctttggaaccaca ctctgggaaatctgctacaatggggagatccccctcaaagacaagaccctggtggagaaa gagagattttatgaaagccgctgcaggccagtgactccatcttgtaaggagctggctgac cttatgactcgctgcatgaactatgatcccaatcagagacccttcttccgggccatcatg agggacattaacaagctggaagagcagaatccagacattgtttcagaaaagaagccaaca acagaggtggatcccactcattttgaaaagcgtttcctgaagaggatccgtgacttggga gagggccactttgggaaggtcgaactctgcagatatgatcctgagggagacaacacaggg gaacaggtggccgtcaagtccctgaagccagagagtggaggtaaccacatagctgatctg aagaaggagatagagatcttacggaacctctaccatgagaacattgtcaagtacaaagga atctgcatggaagatggggggaatggtatcaagctcatcatggagtttctgccttcggga agcctaaaggaatatctgccaaagaataagaacaaaattaacctcaaacagcagctaaac tatgccatccagatttgtaaggggatggactacctgggttctcgacagtatgttcaccgg gacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggagacttt ggtttaaccaaagcaatcgaaactgataaggagtactacacagtcaaggatgaccgtgac agcccggtgttttggtacgctccggaatgtttaatccaatgtaaattttatatcgcctct gatgtgtggtcttttggagtgacactgcacgagctgctcacctactgtgactcggatttt agtcccatggccttgttcctgaaaatgataggcccaactcatggccagatgacagtaaca cggcttgtgaatactctgaaagaaggaaagcgcctgccatgtccacccaactgtcctgac gaggtttatcagctcatgagaaaatgctgggaattccaaccatctaatcggacgacgttt cagaaccttatagaaggattcgaagcacttttaaaataa

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