Mesocricetus auratus (golden hamster): 101843997
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Entry
101843997 CDS
T08306
Symbol
Raf1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X2
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
maua
Mesocricetus auratus (golden hamster)
Pathway
maua01521
EGFR tyrosine kinase inhibitor resistance
maua01522
Endocrine resistance
maua04010
MAPK signaling pathway
maua04012
ErbB signaling pathway
maua04014
Ras signaling pathway
maua04015
Rap1 signaling pathway
maua04022
cGMP-PKG signaling pathway
maua04024
cAMP signaling pathway
maua04062
Chemokine signaling pathway
maua04068
FoxO signaling pathway
maua04071
Sphingolipid signaling pathway
maua04072
Phospholipase D signaling pathway
maua04140
Autophagy - animal
maua04150
mTOR signaling pathway
maua04151
PI3K-Akt signaling pathway
maua04210
Apoptosis
maua04218
Cellular senescence
maua04270
Vascular smooth muscle contraction
maua04360
Axon guidance
maua04370
VEGF signaling pathway
maua04371
Apelin signaling pathway
maua04510
Focal adhesion
maua04540
Gap junction
maua04550
Signaling pathways regulating pluripotency of stem cells
maua04613
Neutrophil extracellular trap formation
maua04625
C-type lectin receptor signaling pathway
maua04630
JAK-STAT signaling pathway
maua04650
Natural killer cell mediated cytotoxicity
maua04660
T cell receptor signaling pathway
maua04662
B cell receptor signaling pathway
maua04664
Fc epsilon RI signaling pathway
maua04666
Fc gamma R-mediated phagocytosis
maua04720
Long-term potentiation
maua04722
Neurotrophin signaling pathway
maua04726
Serotonergic synapse
maua04730
Long-term depression
maua04810
Regulation of actin cytoskeleton
maua04910
Insulin signaling pathway
maua04912
GnRH signaling pathway
maua04914
Progesterone-mediated oocyte maturation
maua04915
Estrogen signaling pathway
maua04916
Melanogenesis
maua04917
Prolactin signaling pathway
maua04919
Thyroid hormone signaling pathway
maua04921
Oxytocin signaling pathway
maua04926
Relaxin signaling pathway
maua04928
Parathyroid hormone synthesis, secretion and action
maua04929
GnRH secretion
maua04935
Growth hormone synthesis, secretion and action
maua05010
Alzheimer disease
maua05022
Pathways of neurodegeneration - multiple diseases
maua05034
Alcoholism
maua05132
Salmonella infection
maua05152
Tuberculosis
maua05160
Hepatitis C
maua05161
Hepatitis B
maua05163
Human cytomegalovirus infection
maua05164
Influenza A
maua05165
Human papillomavirus infection
maua05167
Kaposi sarcoma-associated herpesvirus infection
maua05170
Human immunodeficiency virus 1 infection
maua05200
Pathways in cancer
maua05205
Proteoglycans in cancer
maua05206
MicroRNAs in cancer
maua05207
Chemical carcinogenesis - receptor activation
maua05208
Chemical carcinogenesis - reactive oxygen species
maua05210
Colorectal cancer
maua05211
Renal cell carcinoma
maua05212
Pancreatic cancer
maua05213
Endometrial cancer
maua05214
Glioma
maua05215
Prostate cancer
maua05218
Melanoma
maua05219
Bladder cancer
maua05220
Chronic myeloid leukemia
maua05221
Acute myeloid leukemia
maua05223
Non-small cell lung cancer
maua05224
Breast cancer
maua05225
Hepatocellular carcinoma
maua05226
Gastric cancer
maua05230
Central carbon metabolism in cancer
maua05231
Choline metabolism in cancer
maua05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
maua00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101843997 (Raf1)
04012 ErbB signaling pathway
101843997 (Raf1)
04014 Ras signaling pathway
101843997 (Raf1)
04015 Rap1 signaling pathway
101843997 (Raf1)
04370 VEGF signaling pathway
101843997 (Raf1)
04371 Apelin signaling pathway
101843997 (Raf1)
04630 JAK-STAT signaling pathway
101843997 (Raf1)
04068 FoxO signaling pathway
101843997 (Raf1)
04072 Phospholipase D signaling pathway
101843997 (Raf1)
04071 Sphingolipid signaling pathway
101843997 (Raf1)
04024 cAMP signaling pathway
101843997 (Raf1)
04022 cGMP-PKG signaling pathway
101843997 (Raf1)
04151 PI3K-Akt signaling pathway
101843997 (Raf1)
04150 mTOR signaling pathway
101843997 (Raf1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101843997 (Raf1)
09143 Cell growth and death
04210 Apoptosis
101843997 (Raf1)
04218 Cellular senescence
101843997 (Raf1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101843997 (Raf1)
04540 Gap junction
101843997 (Raf1)
04550 Signaling pathways regulating pluripotency of stem cells
101843997 (Raf1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101843997 (Raf1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
101843997 (Raf1)
04625 C-type lectin receptor signaling pathway
101843997 (Raf1)
04650 Natural killer cell mediated cytotoxicity
101843997 (Raf1)
04660 T cell receptor signaling pathway
101843997 (Raf1)
04662 B cell receptor signaling pathway
101843997 (Raf1)
04664 Fc epsilon RI signaling pathway
101843997 (Raf1)
04666 Fc gamma R-mediated phagocytosis
101843997 (Raf1)
04062 Chemokine signaling pathway
101843997 (Raf1)
09152 Endocrine system
04910 Insulin signaling pathway
101843997 (Raf1)
04929 GnRH secretion
101843997 (Raf1)
04912 GnRH signaling pathway
101843997 (Raf1)
04915 Estrogen signaling pathway
101843997 (Raf1)
04914 Progesterone-mediated oocyte maturation
101843997 (Raf1)
04917 Prolactin signaling pathway
101843997 (Raf1)
04921 Oxytocin signaling pathway
101843997 (Raf1)
04926 Relaxin signaling pathway
101843997 (Raf1)
04935 Growth hormone synthesis, secretion and action
101843997 (Raf1)
04919 Thyroid hormone signaling pathway
101843997 (Raf1)
04928 Parathyroid hormone synthesis, secretion and action
101843997 (Raf1)
04916 Melanogenesis
101843997 (Raf1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101843997 (Raf1)
09156 Nervous system
04726 Serotonergic synapse
101843997 (Raf1)
04720 Long-term potentiation
101843997 (Raf1)
04730 Long-term depression
101843997 (Raf1)
04722 Neurotrophin signaling pathway
101843997 (Raf1)
09158 Development and regeneration
04360 Axon guidance
101843997 (Raf1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101843997 (Raf1)
05206 MicroRNAs in cancer
101843997 (Raf1)
05205 Proteoglycans in cancer
101843997 (Raf1)
05207 Chemical carcinogenesis - receptor activation
101843997 (Raf1)
05208 Chemical carcinogenesis - reactive oxygen species
101843997 (Raf1)
05230 Central carbon metabolism in cancer
101843997 (Raf1)
05231 Choline metabolism in cancer
101843997 (Raf1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101843997 (Raf1)
09162 Cancer: specific types
05210 Colorectal cancer
101843997 (Raf1)
05212 Pancreatic cancer
101843997 (Raf1)
05225 Hepatocellular carcinoma
101843997 (Raf1)
05226 Gastric cancer
101843997 (Raf1)
05214 Glioma
101843997 (Raf1)
05221 Acute myeloid leukemia
101843997 (Raf1)
05220 Chronic myeloid leukemia
101843997 (Raf1)
05218 Melanoma
101843997 (Raf1)
05211 Renal cell carcinoma
101843997 (Raf1)
05219 Bladder cancer
101843997 (Raf1)
05215 Prostate cancer
101843997 (Raf1)
05213 Endometrial cancer
101843997 (Raf1)
05224 Breast cancer
101843997 (Raf1)
05223 Non-small cell lung cancer
101843997 (Raf1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101843997 (Raf1)
05161 Hepatitis B
101843997 (Raf1)
05160 Hepatitis C
101843997 (Raf1)
05164 Influenza A
101843997 (Raf1)
05163 Human cytomegalovirus infection
101843997 (Raf1)
05167 Kaposi sarcoma-associated herpesvirus infection
101843997 (Raf1)
05165 Human papillomavirus infection
101843997 (Raf1)
09171 Infectious disease: bacterial
05132 Salmonella infection
101843997 (Raf1)
05152 Tuberculosis
101843997 (Raf1)
09164 Neurodegenerative disease
05010 Alzheimer disease
101843997 (Raf1)
05022 Pathways of neurodegeneration - multiple diseases
101843997 (Raf1)
09165 Substance dependence
05034 Alcoholism
101843997 (Raf1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101843997 (Raf1)
01522 Endocrine resistance
101843997 (Raf1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
maua01001
]
101843997 (Raf1)
Enzymes [BR:
maua01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101843997 (Raf1)
Protein kinases [BR:
maua01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
101843997 (Raf1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RBD
C1_1
Kinase-like
ABC1
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
101843997
NCBI-ProteinID:
XP_005066169
UniProt:
A0A1U7Q6W2
LinkDB
All DBs
Position
Unknown
AA seq
648 aa
AA seq
DB search
MEHIQGAWKSISNGFGLKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTVGDSGVPALPSLTMRRMRESVSRMPASSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNL
SPTGWSQPKTPVPAQRERAPGSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYSHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggagcttggaagtcgatcagcaatggttttggactcaaagatgcg
gtgtttgatgggtccagctgcatctccccaacaattgttcagcagtttggctatcagcgc
cgggcctcagatgatggcaaactcacagatccttctaagacaagcaacactatccgagtt
ttcttgccgaataagcaaaggaccgtggtcaatgtgcggaatggaatgagcttgcatgac
tgccttatgaaagctctcaaggtgagaggtctgcagccagagtgttgtgcagtgttcaga
cttctccaggaacacaaaggtaagaaagcacgcttggactggaacaccgatgccgcctct
ctgattggagaagaactgcaagtggatttcttggatcacgttccactcacaactcacaac
tttgctcggaaaacgttcctgaagcttgcattctgtgacatctgtcaaaagttcctgcta
aatggatttcggtgtcagacttgtggctacaagtttcatgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacagctcttgctgtttccaaattccact
gttggtgatagtggagtcccagcactaccttctttgacaatgcgtcggatgcgagagtct
gtttcccggatgcctgctagttcccagcacagatactccacacctcatgccttcactttc
aacacctccagcccttcctctgaaggttccctctcccagaggcagaggtcaacatccact
cccaatgtccacatggtcagcaccaccttgcctgtggacagcaggatgattgaggatgca
attcgaagtcacagtgaatcagcctcaccttcagccctgtccagcagccccaacaacctg
agcccaacaggctggtcacagcctaaaacccctgtgccagcacaaagagaacgggcacca
ggatctgggacccaagaaaaaaacaaaattaggcctcgtgggcagagagattcaagctat
tactgggaaatagaagccagtgaggtgatgctgtccactcggattgggtcgggctccttt
ggcactgtgtacaagggcaagtggcacggagatgttgcagtaaagatcctaaaggtggtt
gacccaaccccagagcagcttcaggccttcaggaacgaggtggctgtcttgcgcaaaaca
cggcatgttaacatcctgctgttcatgggctacatgacaaaggacaacctggccattgtg
acccagtggtgtgaaggcagcagtctctataaacacctacatgtccaggagaccaaattc
cagatgttccagctaattgacattgcccgacagacagctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggcctc
acagtgaaaattggagattttggtttggcaacagtgaagtcacgctggagtggttctcag
caggttgaacagcccaccggctctgtgctatggatggccccagaagtaatccgaatgcag
gataacaacccgtttagcttccagtctgatgtctactcctatggcattgtgctttatgag
ctgatgactggggagcttccctactcgcacatcaacaaccgagatcagatcatcttcatg
gtgggccgcggatatgcttccccagaccttagcaggctctacaagaactgccccaaggca
atgaagagattggtggctgactgtgtgaagaaagtaaaggaagagaggcctctgtttccc
cagatcctgtcttccatcgagctgcttcagcactctctgccgaaaatcaacaggagcgcc
tctgagccctctctgcatcgggcagcccacactgaggacatcaatgcttgcacgctgacc
acatccccaaggctaccggtcttctag
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integrated database retrieval system