Mesocricetus auratus (golden hamster): 101844822
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Entry
101844822 CDS
T08306
Symbol
Gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
maua
Mesocricetus auratus (golden hamster)
Pathway
maua00270
Cysteine and methionine metabolism
maua00480
Glutathione metabolism
maua01100
Metabolic pathways
maua01240
Biosynthesis of cofactors
maua04216
Ferroptosis
Module
maua_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
maua00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
101844822 (Gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101844822 (Gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
101844822 (Gclc)
Enzymes [BR:
maua01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
101844822 (Gclc)
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GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
101844822
NCBI-ProteinID:
XP_005073769
UniProt:
A0A1U7QH02
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Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENRKVQLVLSGEDVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSVLEENQALCTITSFPRLGCPGFTMPEHKPNPEEGGASKSLFFPDEAI
NKHPRFGTLTRNIRHRRGEKVVINVPIFKDKNTPSPFVETFPEDEEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNRFRISKSRYDSIDSYLSKCGEKYNDIDLTIDNEIYEQLLR
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKMAQKRDAVL
QGMFYFRKDICKGGNAVVDGCSKAQTGYEPAAEEYTLMSIDTIINGKEGMFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSIITDEINYS
LVLKCNQIANELCECPELLGSGFRKAKYSGGKSDSSH
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaagagacccagcgccacgccgac
cacgtgcggcggcacggcatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggtgacgaggtagaatacatgttggtgtcctttgatcat
gaaaatagaaaagtccagttggtgctgtctggagaagatgttcttgaaactctgcaggag
aagggggaaaggacaaaccccaaccacccaaccctctggagaccggagtatggaagttac
atgattgaagggacacctggccagccctatggaggaacgatgtctgagttcaacacagtg
gaggacaacatgaggaaacgcaggaaggaggctacttctgtgttagaggaaaaccaggct
ctttgcaccataacttctttccccagactaggctgccctggattcacaatgccggaacac
aaaccgaacccagaggaaggcggtgcatccaagtccctcttctttccagatgaagccata
aacaaacacccccgcttcggcaccctaacaagaaacatccggcatagacgaggagaaaag
gtcgttatcaacgtgccaatctttaaagacaagaacacaccatctccatttgtagaaacg
tttcctgaagatgaggaggcagcaaaggcttctaagccagaccatatctacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtaacattccaagcctgcagcatatct
gaagccagatacctttatgatcagttggccactatctgcccaattgttatggctttgagt
gctgcatctccattttaccgaggctacgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaacacgggaggagagaggactggagcccctgaagaacaat
cgctttaggattagtaaatctcggtatgattcaatagatagctacctgtctaagtgtggt
gagaaatacaatgacatcgacctgaccatcgataatgaaatctatgagcagctcttgcga
gaaggcattgatcatcttttggcacagcatgttgcgcatctcttcattagagatccactc
accctttttgaagagaaaatacacctggatgatgccaacgagtctgaccattttgagaat
attcagtccacaaactggcagacaatgagatttaagcctcctcctccaaactcagatatt
ggatggagagtagagttcagacccatggaggtgcagctgacagactttgagaactctgcc
tatgtggtatttgtggttctgctcaccagggtgatcctctcctacaaactcgatttcctc
attccactctccaaggttgatgaaaacatgaaaatggcacagaaacgagatgctgtcttg
caggggatgttttatttcaggaaagacatttgcaaaggtggcaatgcggtggtggatggg
tgtagcaaggctcagaccggctacgagccagcagcagaggagtacaccctcatgagcata
gacaccatcattaacgggaaggaaggtatgttccctgggctcatccccattctgaactcc
tatcttgaaaacatggaagtagacgtggacaccagatgcagtattctgaactacctaaag
ctaattaagaagagagcttctggagaactaatgactgttgccagatggatgagagagttt
attgcaaaccaccctgactacaagcaagacagtataataactgatgagataaattatagc
ctcgttttgaaatgtaaccaaattgcaaatgaattgtgtgaatgtccagagttacttgga
tcaggatttagaaaagccaagtatagtggaggtaaaagcgactcttcccactag
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