KEGG   Mycolicibacterium aurum: NCTC10437_01397
Entry
NCTC10437_01397   CDS       T06794                                 
Symbol
rmlB_2
Name
(GenBank) dTDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
mauu  Mycolicibacterium aurum
Pathway
mauu00521  Streptomycin biosynthesis
mauu00523  Polyketide sugar unit biosynthesis
mauu00525  Acarbose and validamycin biosynthesis
mauu00541  Biosynthesis of various nucleotide sugars
mauu01100  Metabolic pathways
mauu01110  Biosynthesis of secondary metabolites
mauu01250  Biosynthesis of nucleotide sugars
Module
mauu_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:mauu00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    NCTC10437_01397 (rmlB_2)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    NCTC10437_01397 (rmlB_2)
   01055 Biosynthesis of vancomycin group antibiotics
    NCTC10437_01397 (rmlB_2)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    NCTC10437_01397 (rmlB_2)
   00525 Acarbose and validamycin biosynthesis
    NCTC10437_01397 (rmlB_2)
Enzymes [BR:mauu01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     NCTC10437_01397 (rmlB_2)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase RmlD_sub_bind 3Beta_HSD NAD_binding_4 Polysacc_synt_2 adh_short NAD_binding_10 Sacchrp_dh_NADP NAD_binding_8 KR Lipoprotein_Ltp NmrA
Other DBs
NCBI-ProteinID: VEG52314
UniProt: A0A3S4TTD1
LinkDB
Position
1:1427351..1428349
AA seq 332 aa
MARLLVTGGAGFIGSNFVRYVIENTDYEVVVLDKLTYAGNLMSLQNLPERRFRFEHGDIT
DSALVDDLARNADAIVHYAAESHNDNSLSDPRPFLHTNLVGTFTLLEAARKYGSRFHHIS
TDEVYGDLEFDEPERFTETTPYNPSSPYSSTKAGSDLLVRAWVRSFGLAATISNCSNNYG
PYQHVEKFIPRQITNVLLGIRPKLYGEGKNIRDWIHADDHSSAVLAILEKGKLGETYLIG
ADGEKENKSVVELVLALMDQPVDAYDHVADRAGHDLRYAIDSSKLRNELGWSPKYHNFTH
GLESTIDWYRKNRDWWLPAKGVTEQFYARLGQ
NT seq 999 nt   +upstreamnt  +downstreamnt
atggcgcgactgctggtgaccggcggcgcgggcttcatcggatctaatttcgttcgctat
gtaattgaaaacaccgactatgaggtcgtcgtcttagataagttgacttacgccggaaat
ctaatgtcgttgcaaaatctgccggaacggcggtttcgattcgagcacggtgacataact
gattcggcactagtcgacgatctggctcgaaatgcagacgctatcgtccactatgcagcc
gaatctcacaacgataactccttgagtgacccgaggcccttcttgcacaccaacttagtt
ggaacattcactttgctggaggccgcgcgcaagtacggctcgcgtttccatcatatttcg
acggacgaggtgtatggggacttggagttcgatgagcccgaacggtttaccgagacgaca
ccctacaacccttcatcaccgtactcgtcaactaaggctggtagtgatctgctggtacga
gcgtgggtacgttcattcggattagcagcgactatctccaactgctcgaataattacggg
ccttatcagcatgttgagaagttcataccgcgccagatcacgaatgtgctccttgggatc
cgtccgaagctctatggggaaggcaaaaatatccgagactggatccacgccgatgaccat
tcctcggctgtcctggccatcctggaaaagggtaagctcggtgagacctacttgataggc
gccgatggggaaaaggagaacaagtcggtagttgagctagttcttgcgttgatggaccaa
cctgtcgacgcatatgatcacgtagccgaccgggccggtcacgacctgcgttacgcgatt
gattcatctaaattgcgcaatgaattaggctggtcgccaaagtatcacaatttcactcat
gggctagagtctacgatcgattggtatcgtaaaaaccgcgattggtggctccctgctaaa
ggtgtcaccgagcaattttatgcacggctagggcaatga

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