Mycolicibacterium aurum: NCTC10437_02573
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Entry
NCTC10437_02573 CDS
T06794
Symbol
vanB
Name
(GenBank) ATP-grasp enzyme, D-alanine-D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
mauu
Mycolicibacterium aurum
Pathway
mauu00470
D-Amino acid metabolism
mauu00550
Peptidoglycan biosynthesis
mauu01100
Metabolic pathways
mauu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mauu00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
NCTC10437_02573 (vanB)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC10437_02573 (vanB)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC10437_02573 (vanB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
mauu01011
]
NCTC10437_02573 (vanB)
Enzymes [BR:
mauu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
NCTC10437_02573 (vanB)
Peptidoglycan biosynthesis and degradation proteins [BR:
mauu01011
]
Precursor biosynthesis
Amino acid ligase
NCTC10437_02573 (vanB)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
ATP-grasp_4
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
VEG54613
UniProt:
A0A448IQC7
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All DBs
Position
1:complement(2667427..2668476)
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AA seq
349 aa
AA seq
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MSLQTVLHLVGSPVDEFHAELSRLYAGASIAALDDPRRYRTRIAYVAPGGRWCFPDDLSP
EGLSAAVDMSLPQALSHIDQLSVDVMVPQMFCLPGMTAYRSLFDVLGVPYLGSSGDVMAI
GADKARTRAIVGAAGVSVPEGRIVRDRTRTDLTYPVVVKPVSADNSVGVSYVRCDEDYGP
AVDDALAYGDGALVESYVELGREVRCGIVVRDGNPVCLPLEEYTVDATTKPIRTREDKLA
RTDTGALYLVAKDDDHAWTVPVEDPVTERVWDAALACHDALGCRQYSLFDFRIDPHGRPW
FLEAGLYCSYAPGSVVVTMARAAGIGLDQLFADALAELDRGRTACASPS
NT seq
1050 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgttgcagaccgtgctgcacctcgtcgggtcgcccgtcgacgagttccacgccgag
ctgtcgcggctgtacgcgggtgcgagcatcgccgcgctggacgatccgcgccgctaccga
acccgtatcgcgtacgtcgctcccgggggccgctggtgttttcccgacgacctctcgccc
gaggggctgtcggcggcggtcgatatgtcactgccgcaggctctctcacacatcgaccag
ttgtcggtcgacgtgatggtgccgcagatgttctgcctgcccgggatgacggcgtaccgg
tcgctgttcgacgtcctcggtgtgccgtacctgggcagcagcggtgacgtgatggccatc
ggcgccgacaaggcaaggacgcgcgccatcgtcggcgctgcaggcgtcagcgtcccggaa
ggacgcattgtgcgggaccgcacccgcaccgacctgacgtacccggtggtggtcaaaccg
gtgtcggcggacaactccgtgggggtctcctacgtgcggtgcgacgaagactacgggccc
gcggtcgacgacgcactggcctacggcgacggtgcactggtcgagtcctacgtcgaattg
ggccgggaagtgcggtgcggcatcgtcgttcgcgacggcaaccccgtctgccttccactc
gaggagtacaccgtcgacgccacgacgaagccgatccgcacgcgtgaggacaagctggcc
cgcaccgacacgggggcgctgtatctggtggccaaggacgacgatcacgcgtggacggtg
ccggtcgaggatcctgtgaccgagcgggtgtgggacgccgccctcgcgtgccatgacgcg
ctcggatgccggcagtacagcctgttcgatttccgcatcgacccgcacggccggccgtgg
ttcctggaagccgggctgtactgctcgtacgcgccgggcagtgtggtcgtcaccatggca
cgcgcggccggaatcggtctggaccagttgttcgccgacgcactggctgaactcgaccga
ggcaggacagcgtgcgcgtcaccgtcctga
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