Mycobacterium avium 104: MAV_3239 Help Entry MAV_3239          CDS       T00433                                  Name (GenBank) syringomycin synthetase Organism mav  Mycobacterium avium 104 SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Condensation AMP-binding PP-binding AMP-binding_C NAD_binding_4 Epimerase Motif Other DBs NCBI-ProteinID:  ABK67245 UniProt:  A0A0H2ZZW6 LinkDB All DBs Position complement(3340393..3359031) Genome browser AA seq 6212 aa AA seqDB search MLGVGRVGVEDSFFDLGGDSLSAMRLIAAVNGVLGAGVSVRTLFEAPTVAQLAPRVRGGG RTLARVVAGERPAVVPLSFAQSRLWFLDQLQGPSPMYNMAAALKLQGPLDVSVLRAALAD VIARHESLRTVFAVSDGTPHQVVIPAEQADIGWDVVDTAGWSPARMKEAIDAAAGHAFDL STEIPLRATLFRNSLDEHVLVAVAHHIAADGSSLNPLLRDLTAAYTARCAGRVPDWVPLP VQYIDYALWQRAQFGDLEDPDSPIAGQLRYWQEALAGLPERLALPTDRPYPAVADHRGAR VDIDWPASLQQQVSALARVHNATSFMVVQAGLAVLLAKLGASCDVAVGFPIAGRGDPALD DLVGFFVNTLVLRVDLSGDPTVGEILARVRQRSLAAYEHQDVPFEILVERLNPTRSLAHH PLIQVMLTWRGDDPTRLRLGELEVAALPIDIGTARMDLTFSLCERWTEEGRPAGIAGTVE FRTDVFDADTIRTLTERLRRVLDVLTADPGRHLSSIEVLEDTEFARLDIFGNRAALGRST TGASVPALFGAWAQRVPGAVAISSADRCWTYREVDETANRLAHLLIQHGVDRGQYVGLLL DRSAEAVVAILGVLKAGAAYVPMDPAVPAARIAFIVADADLRVVVTDAGSRSRLTGLGAA IVDLDDPALADYPATEPAGPGPAAGDIAHVIYTSGTTGEPKGVAVSHRNITQLFASLDTG ITLGPDQVWSQCHSLAFDFSVWEIWAALLHGGRLVVVSDAVARSPDDLRRLLIRERVTVL TQTPSAAGALSPQGLDSVALVIGAEPCPPELVDRWAPDRVMINVYGPTETTMWVSHSRPL AAGSGAPPIGSPVAGASFFVLDPWLCPAPVGVTGELYVAGAGVGAGYVGRAALTASRFVA CPFGGTGTRMYRTGDLVRWGADGQLHYVGRADEQVKIRGYRIELGEIRSALTDLDGVEQA AVIAREDSPGHKRLVAYLTGTADPAQVRTQLADRLPGYMLPSAVLALDALPLTVNGKLDT RALPAPELRAENRYRAPQNPTEESLADVYARLLGLERVGVDDSFFELGGDSLSAMRLITA VNAELDADLTVRALFEAPTVAQLAPRVAAGTGRAGRLVAAERPAVLPLSFAQSRLWFIDQ LHGPSPVYNMAVALNLRGPLDTDALGAALGDVVARHESLRTLFPAPDGAPRQVVLEAERA EVDWQVVDAARWPASWLAEATHEAARYTFDLATEIPLRAWLFRRNHDEHVLVAVVHHIAA DGWSLTPLVRDLGAAYASRCRGRPPDWAPLPVQYADYTLWQRAQFGDLDDPDSPIATQLQ YWQRALAGMPERVALPTDRPYPLVADHLGASVQVHWPAELQQHIAQLARTHNATSFMVVQ AALAVLLSTLSANPDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDLADDPSIAELLGQV RHRSLQAYENQDVPFELLVERLNPTRSLAHHPLVQVMLAWQNNDPVDVSLGDVHVTPMPL ENQVARMDLVWSLAERWTADGRPDGIDGTVEFRTDVFDAASIETLVRRLQRVLLAMTADP ARPVSSIDILDEPEYAHLDALGNRAALTRPATGWVSISQLFAAQVARTPEAVAISCGERS WTYRELDSSANRLARVLAGRGARPGERVAVLVPRSAGAVVSILAVLKTGAAYVPIDPGLP SARIDFMLADAVPVVTVTTAELRASAGDPDRVVAIDDPAPHVPRIGGRAAPAPDDIAYVI YTSGTTGVPKGVAVTHHNVTQLLGSLDDRLGLGRVWSQCHSLAFDFSVWEIFGALLRGGR LVIVPDDVVRSPEDLHALLIGEGVTVLSQTPSAAAALSPERLESVALVLGGEACPVELMD RWAPGRLMVNQYGPTETTLYATMTTPLRAGGAAVPIGSPVPGAALFVLDGRLRRVPPGVV GELYVAGRGVAAGYLGRAALTASRFVACPFGGTGTRMYRTGDLARWGADGQLHYVGRADE QVKIRGFRIELGEIRSVLAGLDGVEQAAVIARDDGAGHPRLVAYITGTADPAELRAQLAD RLPGYMVPSAVVVLDALPLTGNGKLDTRALPAPDYAGGRYRAPGDAIEEILAGIYAQVLG VERVGVDDSFFDLGGDSILSMQVVARARAAGVMCTARDVFVEQTVARLARVVTVAAADGE LGAADEGIGPVQPTPIMRWLQDIDGPIDEFNQTMVLAAPAGVSQSDVAVVLQALLDRHPM LRLCLDDDGAGGWDLHVPPPGSVDARPILRTVDVLSEAALARARARLNPGAGLMLSAVWA SETSQLALVVHHLAVDGVSWRTLIEDINIAWAQHHSGQEIALPVPGTSFARWSSILAEYA KSPAVVAAAAAWQQVVATPAVLPAVGPDDTYASAGQLSASLDVQTTRLLLGEVPAAFHAG VQDILLIAFGLACTEFVGGGAPIGIDVEGHGRHEEIASGVDLSRTVGWFTTKYPVALRMS RRLDWARVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEIEVQGPDPVIGFNYLG RLGGAAADLSDEHWRLSPDSPSVSAAAAAIPLPLGHTVELNAGTMDTDAGPQLHANWTWA RSVLTDEQLNRLSRLWFEALTGICAHVQAGGGGLTPSDIAPTRLDQGRIEQLERRYDVAD ILPLTPLQQGLLFHATGSHAEGDVYAVQLSVTLRGALDPHRLHRALHTVVTRHPNLAARF CPELGEPVQIIPAEPEIAWRYLELDASDVDEQLEQLSADERAAVRELGDRPPFGAALIRT ADTEHRFVLTVHHLVMDGWSLPVLLQEIFACYYGARLPAPAPYRGFVTWLAARDVPAARA AWRAVLDGFDTPTLVAPRGADAPGRRGVASFRMAAETTSAVSELARRRRTTVNTVLQAAW AQLLMMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPVRARAAAATTIADLLDQLQ CAHNDTVEHQHLGLNEIHRVTGQDQLFDTLLVYENYPIDTAALSAADDLTATEFSCHDYN HYPLSLQVVPGDELGLRLEFDTDVFDPAAIDTLADRLRRLLAAMPADPDRPLRSLDLLDS TEHTRLQRWGNRPALSRPATGPSLPELFTAQVANAPHAVALRCAGRSMTYRELDEASTRL AHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYLPIDPALPATRIEFMLGDAAP VVAVSTAGLRARLEAFGLPVVDVAATGAQPGGPLPPPAPDNIAYLLYTSGTTGVPKGVAV THRNVAQLLESLHASLPGTGVWSQCHSYGFDVSVQEIWGALAGGGRLVVVPESVTSSPDE LHALLIAENVTVLSQTPSALAALSPRNLHAALVIGGEPCPAALADRWAPGRVMINAYGPT ETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDGWLRPVPAGVTGELYIAGAGVAAGYL GRAGLTAARFVACPFGGAGARMYRTGDLVRWDRDGRLHYVARADQQVKIRGHRIELGEIH SALAELDGVEQAAVIAREDRPGEKRIVGYLTGTADPAAIRARLAERLPAYMVPAAVLAIE ALPLTPNGKLDARALPAPEYAGGAYRAPSTPTEEIIAGIYTQVLGLHRVGVDDSFFDLGG DSLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQLAARLGEGGHRFAAVVAAERPAVVPLS FAQSRLWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDVVTRHESLRTVFAATDGT PAQVVLPPDRADIGWQVIDASGWSPARVDDVIRDTARHTFDLAAEIPLRAVLLRCGDEEH LLVAVVHHIAADGWSLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLD DPHSLIAGQLRYWESALAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAG AHNATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDVSG DPTVAELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNIEPTELS LGQVRVIPLPVDTRTARMDLAWSLAERWTPDGSPAGIGGAVEFRTDVFDTATVEALTQRL RRVLAAMTADPGRRLSSIDLLDPDEHARLDALGNRAALTRPQHPPTSIPAMFAAQVARTP HAVALTANGRSVTYRRLEEHANQLAHQLIRYGAGPGRCVAVLLERSAEAVAAILGVLKAG AAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPVTAP PAPAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFD FSVWEIFGALLNGGRVLVVPDDVVRSPEDLCALLIDEHVDVLSQTPSAFDALQRADSARR LNPQTVIFGGEALIPHRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDIDGNVSP IGMPLAHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACPFGGAGE RMYRTGDLARWGTDGQLHYLGRADQQVKIRGYRIELGEIQSALAELDGVEQATVIAREDR PGDKRLVGYVTGTADPAQLRTALAERLPAYLVPAAVVAIDAMPLTPNGKLDTGALPAPDY HGADQYHAPASAVEQTLADIYAHVLDVRPPRLVGIDDSFFDLGGDSLSAMRLVAEVNSRL DVHLGVRALFEAPTIRRLAARLGADGSARAPLVAAERPAVVPLSFAQSRLWFIGQLHGPS PVHNMAIALQLHGRLDAAAFGAALADVVGRHESLRTLFPAHEGIPQQLVIEVDEADIGWQ VIDASGWSPARLDDVIRDTARHTFDLAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGWSL TPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLRYWESA LAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGAHNATSFMVVQAALAV LLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDVSGDPTVAELLARVRQRSL AAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNIEPTELSLGQVRVIPLPVDTRTA RMDLAWSLAERWTPDGSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLAAMTADPGRRLS SIDLLDPAEHARLDALGNRAVLTRPQHPPTSIPEVFAAHVARTPHAVAVTCGRRSWTYRE LDSSANRLAHLLIHHGAGPGDCVALLLERSAEAVAAILGVLKAGAAYLPIDPSLPSARIE FMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPVTAPPAPAPDNIAYLIYTSG TTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWEIFGALLNGGRV LVVPDDVVRSPKDLHALLVAERVDMLTQTPSEVGVLSPDGLESTTLAVAGEACPVEVVDR WAPGRVMINVYGPTETTIVAAVSAPLTPGPEAPPIGAPVPGTALRVLDAHLRPVPPGVVG ELYVAGAGVSTGYLGRPGLTASRFVACPFGGAGERMYRTGDLVRWGADGQLQYLGRADEQ VKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYVTGTADLAQLRTALAER LPGYMVPAAVLMLDALPLTPSGKLDTGALPAPDYQGPEGYLAPAGAVEEILAWLYAQVLG LPRRVGVQESFFDLGGDSLSAMRLVAAIYNALDIHLPVRAVFEAPSVRSLSQRLNADPAV AQGLRADFASVHGRDATEVYASDLTLDKFIDAATLSAAPALPGPGAEVRTVLLTGATGFL GRYLVLQWLERLELADGKLICLVRAASDDDARRRLERTFDSGDPALLRYFHELAADHLEV IAGDKGRANLGLDDRTWQRLADTVDLIVDAAAVVNGVLPYQELFGPNVAGTAELIRLALS TRLKPYSYVSTANVGDQIEPSAFTEDADIRVAGPIRTIDGGYGNGYGNSKWAGEVLLREA HDLCGLPVSVFRCDMILADTSYAGQLNLPDMFTRLLFSVVASGVAPRSFYRLDAHGNRQR AHFDALPVEFVAEAIATLGAQVGRDAGTGFATYHVMNPHDDGIGLDEYVDWLIDAGYPIE RVDDFDQWLHRMETALHALSERQRHQSVLQLLALRNARHVPPADPARGCLGPTERFRAAV QEAKIGADNDIPHITAPVIVKYVTDLQLLGLL NT seq 18639 nt NT seq  +upstreamnt  +downstreamnt gtgttgggggtggggcgggttggggttgaggattcgttttttgatttggggggtgattcg ctgtcggcgatgcggttgatcgcggcggtcaatggtgtgttgggtgctggggtttcggtg cgtacgttgtttgaggcgcctacggttgcgcagttggcgcctcgggtgcgcggtggtggc cgcacgcttgctcgggtggtggcgggtgagcggccggcggtggttccgttgtcgtttgcc cagtcccggttgtggttcctcgaccaactgcagggtccctcacccatgtacaacatggcg gcggcgctgaagttacaggggccgcttgatgtttcggtgctgcgcgccgcgctggccgac gtgatcgcccggcacgagagcctgcgtaccgtgttcgccgtctccgacggcacaccgcac caggtcgtgattcccgccgaacaagccgacatcggctgggacgtggttgacaccgccggc tggtcgccggcacggatgaaggaggccatcgatgccgcggcaggtcatgcctttgatctc tccaccgaaataccattgcgtgcaacgcttttccggaacagcctggacgagcatgtgctg gtggcggtggcccatcatattgctgcggatggttcgtcgctgaatcctttgctgcgcgac ctgaccgccgcctacaccgcccgctgcgccgggcgggttccggattgggtgccgttgccg gtgcagtacatcgattacgcgctgtggcagcgggcgcagttcggtgatctcgaggacccg gacagtccgatcgcggggcagttgcgttattggcaggaggcgttggccgggttgcccgag cggttggcgttgccgacggatcggccgtatccggcggtggctgatcatcgtggggctcgg gtggacatcgactggccggcgtcgctgcagcagcaggtatcggccctggcccgggtgcat aacgcgaccagtttcatggtggtgcaggccggcttggcggtgctgctggccaagctcggt gcgagttgtgatgtggcggtgggttttccgattgccgggcgtggtgacccggctcttgat gacctggtcgggttcttcgtcaacaccctggtgctgcgcgtcgatttgtccggtgatccc accgtcggcgaaatcctggcccgggtgcgccaacgcagcctggccgcctacgaacaccag gacgtgcccttcgaaatcctggtcgagcggctcaaccccacccgatcgctggcccaccac ccactgattcaggtgatgttgacctggcgcggcgacgatccgacgcggctgcgcctgggc gagctggaggtcgcggcgctgccgatcgacatcggcaccgctcgaatggatctgaccttc tccctgtgcgaacgctggaccgaggagggccggcccgccggcatcgccggaacggtggaa ttccgcaccgacgtcttcgacgcggacaccatccgcaccctcaccgagcggctgcgccgg gtgctcgacgtcctgaccgccgacccgggccggcacctctcgtcgatcgaggtgctcgag gacaccgagtttgcccggctcgacatattcggcaaccgcgcggcgctgggccggtcaacg acgggcgcctcggtgcccgcgctgttcggcgcctgggcgcagcgggtgccgggggcggtg gcgatcagcagcgcggaccgctgctggacctatcgggaggtcgacgagacagcgaatcgg ctggcgcacttgctgattcagcacggcgtggaccgggggcagtacgtggggttgctgctg gaccgttccgccgaggcggtcgtcgcgatcctgggggtactgaaggcgggcgcggcgtac gtgccgatggatccggcggtgccggcggcgcggatagccttcatcgtcgccgacgccgat ctgcgggtggtggtgaccgatgcgggatcgcgctcccggctgaccgggctcggcgcggcg atcgtcgacctcgacgatccggcgttggcggactacccggccaccgaaccggccggcccg ggcccggccgccggcgacatcgcccacgtgatctacacctcgggcaccaccggcgaaccc aagggagtggccgtcagccaccgcaacatcacccaactgttcgcgtcgctggacaccggc atcaccctgggaccggatcaggtgtggagccagtgccattcgctggcattcgacttctcg gtgtgggagatctgggccgcgctgctgcacggcgggcggctcgtggtggtgtccgacgcg gtggcccgctcaccggatgacctgcggcgcttgctgattcgcgagcgcgtcacggtgttg acgcagacgccgtcggcggccggggcactgtcgccgcaggggctggactcggtcgccctg gtgatcggggcggagccgtgcccgcccgagttggtggaccgctgggcgccggaccgggtg atgatcaacgtctacgggccgaccgagaccaccatgtgggtgtcgcacagtaggccgttg gcggcgggctcgggcgcaccgccgatcgggtcgccggtggccggggcatcgtttttcgtg ttggacccctggttatgcccggccccggtgggggtcacgggggagctgtatgtggcgggc gccggggtgggcgccggctatgtgggccgcgcggccttgacggcgtcgcggtttgtcgcc tgcccgttcggtggtaccggcacccgcatgtaccgcaccggcgacctggtccgctggggt gccgacgggcagctgcactacgtgggccgggccgacgagcaggtcaagattcgcgggtat cgcatcgagctcggcgaaatccgttccgcgctcaccgatctcgacggcgtcgagcaggct gcggtgatcgcccgagaggacagccccggtcacaaacgcctggtcgcctacctcaccggg accgccgaccccgcgcaggtccgcacccagctggccgaccggctgcccggctacatgctg ccgtcggcggtgctggcgctcgacgcgctgccgctgacggtcaacggcaagctggacacc cgcgccctgcccgcccccgagctccgcgccgaaaaccgttaccgcgcaccgcaaaacccc accgaggaaagcctggccgacgtctacgcccgcctcctcggactggaacgggtaggggtc gacgattccttcttcgaactcggcggcgactcgctgtcggccatgcggctgatcaccgcg gtcaacgccgagttggacgccgacctgaccgtccgcgccctgttcgaggcacccaccgtc gcccaactggcgccccgcgtcgcggccggcaccggcagggccgggcgattggtggccgcg gaacgcccggcggtgctgccgctgtcgttcgcccaatcccggctgtggttcatcgaccag ttgcacggcccgtcgcccgtgtacaacatggcggtcgcattgaacctgcgcgggccgctg gacacggacgcgctgggcgccgccctgggcgacgtggtggcccgccacgagagcctgcgt accctgttcccggcgcccgacggggcaccccgacaagtggtgctcgaggccgaacgcgcc gaggtcgattggcaggtcgtcgacgcggcgcggtggccggcgtcctggctggcggaggcc acccacgaggcagcgcgctacaccttcgacctggccaccgagatccccttgcgcgcatgg cttttccggcgcaaccacgacgagcacgtgctggtggcggtggtccaccacatcgccgcg gacggatggtcgctgaccccgctggtgcgcgacctgggcgccgcgtatgccagccggtgc cgcgggcggcccccggactgggcgccgctgccggtgcagtacgccgactacacgctgtgg cagcgagcgcaattcggtgacctcgacgaccccgacagcccgatcgccacccaactgcag tactggcagcgagccctggccgggatgccggaacgcgtcgcgctgcccaccgatcggccc tacccgctggtcgccgaccatctcggcgcgagcgtgcaggtacactggccggccgaactg cagcagcacatcgcccagctggcccggacgcacaacgccaccagcttcatggtggtgcag gccgccctggcggtgctgctgtccaccctgagtgcgaatcccgatgtggccgttggtttc ccgatcgccggccggcgcgaccccgcgctggacgacgtggtcgggtttttcgtcaacacc ctggtgctgcgcgtcgacctggccgacgaccccagtatcgccgagctgctgggccaggtg cgccaccgcagcctgcaggcctacgaaaaccaggacgtgcccttcgagctactggtggaa cggctgaaccccacccgcagcctcgcccaccatccgctggtccaggtgatgctggcctgg cagaacaacgacccggtcgatgtgagcctgggcgacgtgcacgtcacgccgatgccgctg gaaaaccaggtcgcccgaatggatctggtgtggtcgctggccgaacgctggacagcggac ggccggcccgacggcatcgacggcacggtggagttccgcaccgacgtcttcgacgcggcc agcatcgaaacactcgtgcgccgcttgcagcgggtgttgctcgccatgaccgccgatccc gcccggccggtgtcgtcgatcgacatcctcgacgaaccggagtacgcccacctcgacgcg ctcggcaaccgtgccgcgctgacccgaccggcgaccgggtgggtgtcgatttcgcagctg ttcgccgcccaggtggcgcgcacccccgaggcggtggcgatcagctgcggcgagcggtcc tggacctaccgcgaactcgactcgtcggcaaaccggctggcgcgcgtgctggccggccgg ggcgcccgcccgggcgagcgggtcgccgtgctggtcccgcggtccgccggcgcggtggtg tccatcctggcggtgctcaagaccggcgccgcgtacgtcccgatcgaccccggattgccc tcggcgcgaatcgatttcatgctcgccgacgccgtgcccgtcgtcacggtcaccaccgcc gaactgcgcgcttcggccggcgacccagatcgggtcgtcgccatcgacgaccctgccccg cacgtcccgcgcatcggcgggcgggcggccccggcgccggatgacatcgcctacgtcatc tacacctccggcaccaccggcgttcccaagggggtcgcggtcactcaccacaacgtcacc cagctgcttggctcgctggacgaccgattgggcctcggccgggtatggagccagtgccat tcgctggcgttcgacttctcggtgtgggagatcttcggcgcgctgctgcgcggcgggcgg ctggtcatcgtgcccgacgacgtcgtccggtcgccggaagacctgcacgccttgctgatc ggcgagggcgtcaccgtgctgagccagaccccgtcggcggcggcggcgttgtcgccggaa cggctggaatcggtggcgctggtgctcggcggtgaggcctgcccggtcgagctgatggac cgctgggcgcccggccggctgatggtcaaccagtacgggcccaccgagaccacgctgtac gcgacgatgaccacgccgctgcgtgcgggcggcgccgcggtgccgatcggctcgccggtg cccggggcggcgctgttcgtgctggacggccggctgcgccgggtgccgcccggcgtggtg ggcgagctgtacgtggccggccgcggtgtggccgccggctatctcggccgcgcggccttg acggcgtcgcggtttgtcgcctgcccgttcggtggtaccggcacccgcatgtaccgcacc ggcgacctggcgcgctggggtgccgacgggcagctgcactacgtgggccgggccgacgag caggtcaagattcgcgggttccgcatcgagctcggcgaaatccgttccgtgctggccggt ttggacggggtggagcaggccgcggtgatcgcccgcgacgacggcgccgggcacccgcga ctggtggcctacatcaccggcaccgcggacccggccgagctgcgcgcgcagctggccgac cgactgcccggctacatggtgccctcggcggtggtggtgctggacgcgctgccgctgacc ggcaacggcaagctggacacccgcgccctgcccgcacccgactacgccggcggccgttac cgggccccgggcgacgcgatcgaggagatcctggccggcatctacgcccaggtgctgggc gtggagcgggtcggggtggacgactcgttcttcgacctgggcggcgacagcatcctgtcc atgcaggtggtggcacgggcccgggccgccggcgtgatgtgcacggcccgagacgttttc gtcgaacagacggtggcccggctggcccgggtcgtcaccgtggccgccgccgacggcgag ttgggcgcggccgacgaggggatcgggccggtgcagcccaccccgatcatgcgctggctg caggacatcgacggcccgatcgacgagttcaaccagaccatggtgctggccgccccggcg ggggtgagccaatccgacgtggcggtggtgctgcaggcgctgctggatcggcatccgatg ctgcggctgtgcctcgacgacgacggcgccggcggctgggacctgcacgtgccgcccccc ggttcggttgacgcccgccccatcctgcgcaccgtcgatgtgctctccgaggccgcgctg gcccgggcccgggcccggctgaaccccggcgccggcctgatgctgtccgcggtatgggca agcgagacaagccaattggcgttggttgttcatcacctggcggttgatggggtgtcgtgg cggacgttgatcgaggacatcaacatcgcctgggcgcagcatcacagcggtcaggagatc gcgttgccggtgccgggcacgtcgtttgcgcggtggtcgtcgattctggccgagtacgcc aagagtccggcggtggtggctgcggcggcggcgtggcagcaggtggtggccacgccggcg gtgttgccggcggtggggcccgatgacacgtatgcgtcggcggggcagttgtcggcgtcg ctggatgtgcagaccacccggttgttgttgggggaggtgccggcggcgtttcacgctggg gtgcaagacattttgttgattgcgttcgggttggcctgcacggagttcgtgggtggtggc gcgccgatcggtatcgacgtggagggtcacgggcggcacgaggagatcgcctcgggggtg gatctgtctcgtacggtgggctggttcaccacgaaatatcctgtggcactgaggatgagc cggcgtctggattgggcgcgggtggtggcgggggaggccgcgctgggcgcggtgatcaag gatgccaaggagcagttgcgggcgctgcccgacggcctgagctacgggttgctgcgctac ttgaaccccgagatcgaggtgcaggggccggatccggtgatcggattcaactacctgggc cggctcggcggcgcggccgccgacctgtccgacgagcactggcgcctcagccccgacagt ccctcggtgagcgccgcggccgcggcgatcccactgccgttgggacataccgtcgaactc aacgccggcaccatggacaccgacgccggcccgcagttgcacgccaactggacctgggcg cgctccgtgctcaccgacgagcagctaaaccggttgagccggttgtggttcgaggcgctg accggcatctgcgcgcacgtgcaggccggcggcggcgggctgacgccgtccgacatcgcg cccacccgcctcgaccaaggccggatcgagcagctggaacggcgctacgacgtcgccgac atcctgccgctgaccccgctgcagcaggggctgctgttccacgcgaccggaagccatgcc gagggcgacgtctacgcggtgcagctgagcgtcacgctgcgcggcgccctcgacccgcac cggctacaccgcgccctgcacaccgtcgtcacccgccacccgaacctggccgcccgcttc tgccccgagctcggcgagccggtgcagatcattcccgccgaacccgaaatagcttggcgc tacctcgaactcgacgccagcgacgtcgacgaacagctcgagcagctgtccgcggacgaa cgcgccgcggtgcgagagctcggcgaccgcccgccgtttggcgccgcgctgatccgcacc gcggacacggaacaccggttcgtgctcaccgtccaccacctggtgatggacggttggtcg ctgccggtgctgctgcaggaaatcttcgcctgctactacggtgcccggctgccggcgccg gcgccgtaccgcggcttcgtcacctggctggcggcccgcgacgtgccggccgcccgcgcc gcatggcgcgcggtgctcgacggtttcgacacccccaccctggtggccccgcggggtgcc gacgcgcccgggcggcgcggggtcgcctcgttccggatggcggccgaaaccaccagcgcg gtaagcgaactcgcacgccgccgccgcaccaccgtcaacaccgtgttgcaggccgcctgg gcgcagctgctgatgatgctgaccggccagcacgacgtcgcgttcggcaccgccgtctcc ggccggccggccgagctgcccggcgccgagtcgatggtcgggctgttgatcaacaccgtc ccggtgcgcgcccgcgccgccgcggcgaccaccatcgcggatctcctcgaccagctgcag tgcgcccacaacgacaccgtggagcatcagcatttgggactcaacgaaatccaccgcgtc accggacaggaccaactcttcgacaccctgctggtctacgagaactatccgatcgacacc gccgcgctgtcggccgccgacgacctcaccgccaccgaattcagctgccacgactacaac cactacccgctgtcgctgcaggtggtgcccggcgacgaactgggccttcgcctcgaattc gacaccgacgtgttcgacccggcggccatcgacaccctggccgaccggttgcggaggctg ctggccgccatgcccgccgacccggaccgcccgttgcgatcactggacctgctcgactcc accgagcacacccggctgcaacggtggggcaaccggccggcgctgagccggccggcaacc gggccgtcgctgccggagttgttcaccgcacaggtcgccaacgctccgcacgccgtcgcg ctgcgctgcgccggccgctcgatgacctatcgcgaactcgacgaggcgtcgacccggctg gcccacctgctggccggccacggcgccaccccgggttgctttgtggcactgctgttttcc cggtcggccgaggcgatcgtcgcgatgctggcggtgctgaaaaccggcgcggcctacctg ccgatcgacccggcgctgccggcgacccgcatcgagttcatgctcggcgacgccgcaccc gtcgtcgcggtcagcaccgccggcctgcgcgcccggctggaggccttcggcctgccggtc gtcgacgtcgccgccaccggcgcccagcccggcggcccgttgccgccgcccgcgcccgac aacatcgcctatctgctctacacgtccgggaccaccggcgtccccaaaggcgttgcggtc acccaccgcaacgtcgcccagctgctcgagtccctgcacgcgtcgctgcccggcaccggg gtgtggtcgcagtgccactcctacggcttcgacgtctcggtccaggagatctggggcgcc ctggccggcgggggccggctggtggtggtgcccgagtcggtgaccagctcacccgacgag ctgcacgcgctgctgatcgccgagaacgtcaccgtgctcagccagacaccgtcggcgctg gcggcgctgtcaccacgaaacctgcacgcggcgttggtgatcggcggcgagccctgcccg gccgcgctcgccgaccggtgggcgcccggccgggtgatgatcaacgcctacggccccacg gaaaccaccgtcgacgcggtgctcagcacaccgctggccgccggcgccggagcaccccca ctcggctccccggtagcaggtgcgacgctgttcgtgctggatggatggctgcggccggtg cctgccggtgtgaccggcgagctctatatcgccggcgccggggtggccgccggctatctg ggccgcgccggtctgacggcggcgcggttcgtggcctgcccgttcggcggcgccggtgcg cgaatgtaccgcaccggcgatctggtgcgctgggatcgcgacggccggctgcactacgtc gcccgggccgatcagcaggtcaagatccgcggccaccgcatcgagctgggcgaaatccat tctgcgctggccgaactggacggcgtcgagcaggcggcggtgatcgcccgcgaggaccgc cccggcgagaaacggatcgtcggctacctcaccggcaccgccgacccggcggcgatccgc gcccggctggccgagcggttgccggcctacatggttcccgccgcggtgctggcgatcgag gcgctgccgttgactcccaacgggaaactggacgcccgggccctgccagcgccggaatac gcgggcggggcataccgggcgccatccactcccaccgaggagatcatcgccggcatctac acccaggtgcttggcctgcacagggttggtgtcgacgactcgttcttcgacctgggcggt gattcgctgtcggcgatgcgggtgatcgccgccgtcaacgccggcctcgacgcccggctg tcggtgcgagtgttgttcgaagcgcccaccattgcgcaactggcggcgcgcctcggcgaa ggcgggcaccggttcgccgcggtggtggccgccgagcggccggcggtggtgccgttgtcg ttcgcgcagtcgcggctgtggttcatcggccagctgcacgggccgtccccggtgtacaac atggtggccgcgctgcggctgcacgggccggtggacatcggcgcgctgggcgccgcactg catgatgtcgtgacccggcacgagagcctgcgcacggtgttcgccgcgaccgacgggacg cccgcccaagtggtgctgccgcccgaccgtgccgacatcggctggcaggtcatcgacgcc agtggctggtcgccggcccgagtggatgacgtcatccgcgacaccgcccggcataccttt gaccttgctgctgaaattcctttgcgtgcagtgcttttgcggtgtggtgacgaggagcat ttgttggtggcggtggtgcatcatattgccgcggacgggtggtcgttgacgccgttggtg cgtgacttggcgcgggcgtatgcgagtcggtcggcggggcgggtcccggattgggtgccg ttgccggtgcagtatgtcgattacacgttgtggcagcgcgcccagttcggtgacctcgac gacccgcacagcctgatcgccggtcagctgcgctactgggaaagcgcgttggcgggcatg cccgagcggttggaattgcccaccgatcggccgtatccggtggtggccgatttccgcggc gccagtgtcgcggtggagtggccggcgcagttgcagcagcaaatatcgcggttggccggc gcgcataatgccaccagtttcatggtggtgcaggccgcgttggcggtgctgctggccaag gtgagcgcgagttcggatgtggcggtgggctttccgatcgctgggcggcgcgacccggcg ctggatgacgtggtgggttttttcgtcaacaccttggtgctgcgggtggacgtctccggt gatcccacggtggccgagctgctggcgcgggtgcggcaacgcagcctggctgcctatgag catcaggatgtgccgttcgaggtgctggtggagcggctcaacccggcccgcagcctggcg caccatccgctggtgcaggtgatgttggcctggcagaacatcgagcccaccgagctgagc ctggggcaggtgcgggtgattccgctgccggtggatacccgcaccgcccggatggatctg gcctggtcgctggccgaacgctggacacccgatggctcccccgccggtatcgggggagcg gtcgaattccgcaccgacgtgttcgacaccgccacggtcgaggcgttgacccagcgactg cggcgggtgctggcggccatgaccgccgaccccggccgccggttgtcctcgatcgacctg ctcgaccccgacgagcacgcccgcctcgatgccctcggcaaccgcgcagcactgacccga ccacaacacccgcccacctccatccccgcgatgttcgccgcccaggtggcgcgcaccccg cacgccgtggcgctgaccgccaacggtcgctcggtcacctatcgtcggcttgaggaacac gcaaaccaattggcgcaccaacttattcgttacggcgcagggccgggccgctgcgtggcc gtgctgctggagcgttccgccgaggccgtcgcggccatcctgggggtgctcaaggccggg gccgcctacctgcccatcgaccccagcctgcccagcgcacggatcgagttcatgctcacc gacgccgcacccgcggccgtgctcaccagcaccgaattccattgccgcctacaggagtac gaccagaccgtcatcgacgtcgacgacccgtcgatccgggaacaacccgtcaccgcacca cccgcacccgccccggacaatatcgcctacctcatctacacctcgggcaccaccggcgtc cccaaaggcgtcgcggtcacccaccgcaacgccacccagctgttcgcgtcgctgggagcc gccggcctgcccgccgcacccggaaaggtgtggggccagtgccattcgctggccttcgac ttctcagtgtgggagatcttcggcgcgctcctgaacggcgggcgcgtgctggtggtgccc gacgacgtggtccgctccccggaagacctatgcgccttgctgatcgacgaacatgtcgac gtgctcagccaaacgccgtcggcattcgatgcgctgcagcgcgccgactccgcccggcgg ctcaacccgcagacggtgatcttcgggggcgaagcgctgatcccgcaccggctgggcggc tggctggacgggcatcccgcacgcccgcggctgatcaacatgtacggcatcaccgagacg acggtgcacgcctcgttccgggagatcgtcgacggcgacatcgacggcaacgtcagcccg atcggaatgcccttggcgcacttgggattcttcgtgctggatggatggctgcggccggtg cctgccggtgtgaccggcgagctctatatcgccggcgccggggtggccgccggctatctg ggccggcccggtctgacggcgtcacggttcgtggcctgcccgttcggcggcgccggcgag cgaatgtaccgcaccggggacctggcccggtggggcaccgacgggcagctgcactacctg ggccgcgccgatcagcaggtcaagattcgcggctaccggatcgaactcggcgaaatccag tccgccctggccgaattggacggcgtcgagcaggcgacggtgatcgcccgcgaggaccgc cccggcgacaagcggctggtcggctacgtcaccgggaccgccgacccggcgcagctccgc accgcgctggccgaacggctgcccgcctacctggtccccgcggccgtggtcgcgatcgac gcaatgccgttgacgcccaacggaaaactcgacaccggcgccctgcccgcccccgactac cacggcgccgaccagtaccacgccccggcgagcgcggtcgagcagaccctggccgacatc tatgcccacgtcctggacgtgcggccgccccggctggtcggcatcgacgactcgttcttc gacctgggcggtgattcgctgtcggccatgcggctggtcgcggaggtcaactcccgcctc gacgtccacctcggcgtccgggccctgttcgaggcgcccaccattcggcggctggccgcg cggctgggggccgacgggtcggcgcgtgcgccgctggtggccgccgagcggccggcggtg gtgccgttgtcgttcgcccagtcgcggctgtggttcatcggccagctgcacgggccgtcg ccggtgcacaacatggccatcgcgttgcagctgcacgggcgcctcgacgcggcggcgttc ggcgcggcgctggccgacgtggtgggccgccacgagagcctgcgcaccctgttccccgcc cacgagggcataccccagcagctggtgatcgaggtcgacgaggccgacatcggctggcag gtcatcgacgccagtggctggtcgccggcccgactggatgacgtcatccgcgacaccgcc cggcatacctttgaccttgctgctgaaattcctttgcgtgcagtgcttttgcggtgtggt gacgaggagcatttgttggtggcggtggtgcatcatattgccgcggacgggtggtcgttg acgccgttggtgcgtgacttggcgcgggcgtatgcgagtcggtcggcggggcgggtcccg gattgggtgccgttgccggtgcagtatgtcgattacacgttgtggcagcgcgcccagttc ggtgacctcgacgacccgcacagcctgatcgccggtcagctgcgctactgggaaagcgcg ttggcgggcatgcccgagcggttggaattgcccaccgatcggccgtatccggtggtggcc gatttccgcggcgccagtgtcgcggtggagtggccggcgcagttgcagcagcaaatatcg cggttggccggcgcgcataatgccaccagtttcatggtggtgcaggccgcgttggcggtg ctgctggccaaggtgagcgcgagttcggatgtggcggtgggctttccgatcgctgggcgg cgcgacccggcgctggatgacgtggtgggttttttcgtcaacaccttggtgctgcgggtg gacgtctccggtgatcccacggtggccgagctgctggcgcgggtgcggcaacgcagcctg gctgcctatgagcatcaggatgtgccgttcgaggtgctggtggagcggctcaacccggcc cgcagcctggcgcaccatccgctggtgcaggtgatgttggcctggcagaacatcgagccc accgagctgagcctggggcaggtgcgggtgattccgctgccggtggatacccgcaccgcc cggatggatctggcctggtcgctggccgaacgctggacacccgatggctcccccgccggt atcgggggagcggtcgaattccgcaccgacgtgttcgacaccgccacggtcgaggcgttg acccagcggttgcgccgggtgctggcggccatgaccgccgaccccggccgccggttgtcc tcgatcgacctgctcgaccccgccgagcacgcccgcctcgatgccctcggcaaccgcgca gtactgacccgaccacaacacccgcccacctccatcccggaggtattcgccgcgcacgtc gcccgcaccccgcacgcggtggccgtcacttgcgggcggcgttcgtggacctaccgtgaa ctggactcctcggcaaaccggttggcgcacttgctcatccaccacggcgcagggccgggc gattgcgtggcactgctgctcgagcgttccgccgaggccgtcgcggccatcctgggggtg ctcaaggccggggccgcctacctgcccatcgaccccagcctgcccagcgcacggatcgag ttcatgctcaccgacgccgcacccgcggccgtgctcaccagcaccgaattccattgccgc ctacaggagtacgaccagaccgtcatcgacgtcgacgacccgtcgatccgggaacaaccc gtcaccgcaccacccgcacccgccccggacaatatcgcctacctcatctacacctcgggc accaccggcgtccccaaaggcgtcgcggtcacccaccgcaacgccacccagctgttcgcg tcgctgggagccgccggcctgcccgccgcacccggaaaggtgtggggccagtgccattcg ctggccttcgacttctcagtgtgggagatcttcggcgcgctcctgaacggcgggcgcgtg ctggtggtgcccgacgacgtggtccgctcgccaaaagacctgcacgccttgctcgttgcg gaacgcgtcgacatgttgacccagacgccgtccgaggtgggcgtgctctcacccgacggt ctggagtcgacgacgctggcggtcgccggcgaggcctgcccggtcgaggtggtggaccgc tgggcgcccggccgggtgatgatcaacgtctacgggcccacggagaccaccatcgtcgcc gccgtcagcgcgccgctgacccctggccccgaggcgccgccgatcggtgcgcccgtgccg gggaccgcgctgagagtgctcgacgcacacctgcggccggtgccccccggtgtggtcggc gagttgtacgtggccggcgccggggtatcgaccggctacctgggccggcccggcctgacg gcgtcgcggttcgtggcctgcccgttcggcggcgccggcgagcggatgtatcgcaccggg gacctggtccggtggggcgccgacgggcaactgcaatacctcggccgggccgacgagcag gtcaagatccgcggctaccgcatcgaactcggcgaaatccagtccgccctggccgcgctc gacggcgtggaccaggccgccgtcatcgcccgcgaggaccggcccggcgacaagcggctg gtcggctacgtcaccgggaccgccgacctggcgcagctccgcaccgcgctggccgaacgg ctgcccggctacatggtgcccgccgcggtgctgatgctggacgcgctgccattgacaccc agcggcaaactcgacaccggcgccctgcccgcccccgactaccagggccccgagggctac ctggccccggccggcgcggtggaggagatcctggcctggctctacgcccaggtgctgggg ctgccgcggcgggtcggggtgcaggaatccttcttcgacctgggcggcgactcgctgtcg gccatgcggctggtcgcggccatctacaacgcgctggacatccacctgccggtgcgggcc gtcttcgaggcgccctcggtgcgcagcctgagccagcggctgaacgccgatcccgctgtg gcgcaaggccttcgggccgacttcgcatcggtgcacggccgcgacgccaccgaggtgtac gccagcgacctgaccctggacaagttcatcgacgccgcgacgctgtccgccgcacccgcg ctgcccggccccggcgccgaggtgcgcaccgtgctgctgaccggcgccaccggcttcctg ggccgctacctggtgctgcaatggctggaacgcctggaactggccgacgggaaactcatc tgtctggtgcgggccgcctcggacgacgacgcgcggcgccgcctcgagcgcactttcgac agcggcgatcccgccctgctgcggtacttccacgaactggccgccgaccacctcgaagtc atcgccggcgacaagggccgcgccaacctcggcctggacgatcggacctggcagcggctg gccgacaccgtcgacctgatcgtcgacgcggcggccgtcgtcaacggcgtgctgccctac caggaactgttcggccccaacgtcgccggcaccgccgaactgatccggctggcgctgtcc accagactcaagccgtacagctacgtgtcgaccgccaacgtcggcgaccagatcgagccg tcggcgttcaccgaggacgccgacatccgggtcgccgggccgatccgcaccatcgacggc ggctacggcaacggctacggcaacagcaagtgggccggcgaagtgttgctgcgcgaggcg cacgacctgtgcgggctgccggtctcggtgttccgctgcgacatgatcctggccgacacc agctacgcgggccagctcaacctgccggacatgttcacccggctgctgttcagcgtggtg gccagcggcgtggcgccgcgctcgttctaccggctcgacgcgcacggcaaccggcagcgc gcgcacttcgacgcgctgccggtcgagttcgtcgccgaggcgatcgccacgctgggcgcc caggtgggccgggacgccggcaccgggttcgcgacctaccacgtgatgaacccgcacgac gacggcatcgggctcgacgagtacgtcgactggctgatcgacgcgggttacccgatcgag cgggtcgacgacttcgaccagtggctgcaccggatggagaccgcgctgcacgccctgtcg gaacggcagcgccaccagtcggtgctgcagctgctggcgttgcgcaacgcccggcacgtg ccgccggccgacccggcccgcggctgcctggggcccaccgagcggttccgcgccgcggtg caagaagccaaaattggcgccgacaacgacatcccgcacatcaccgccccggtcatcgtc aaatacgtgaccgacctgcagttgctgggcttgctctga

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