Mycobacterium avium subsp. paratuberculosis E1: RC58_17680
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Entry
RC58_17680 CDS
T03787
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mavi
Mycobacterium avium subsp. paratuberculosis E1
Pathway
mavi00290
Valine, leucine and isoleucine biosynthesis
mavi00620
Pyruvate metabolism
mavi01100
Metabolic pathways
mavi01110
Biosynthesis of secondary metabolites
mavi01210
2-Oxocarboxylic acid metabolism
mavi01230
Biosynthesis of amino acids
Module
mavi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mavi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
RC58_17680
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
RC58_17680
Enzymes [BR:
mavi01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
RC58_17680
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AJK76627
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All DBs
Position
complement(3832571..3834370)
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AA seq
599 aa
AA seq
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MTSHPDAFSSSRSIVKPAGPPGPGQPAWNPQRGSSMPVNRYRPFAEEVEPIRLPDRTWPD
KVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFV
REIITEGAIPDDVTIQVLTQCRPELIERTFAACQGAPQAIVHFYNSTSILQRRVVFRADR
AAVQEIAVAGARKCVEEAAKYPETQWRFEYSPESYTGTELEYAKQVCDAVGEIIRPTTEN
PIIFNLPATVEMATPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGYAAGA
DRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHP
YGGDLVYTAFSGSHQDAINKGLDQMKIDADAADTDVEDMLWQVPYLPIDPKDVGRTYEAV
IRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSQVIQKISEGEGGEVSPKEMWDAFFEEY
LAPVWPLERVKQRVDASDEDSGVTSISATVKINGEQTEINGTGNGPLAAFVHALAGVGFD
VAVLDYSEHAMSSGDDAQAAAYVEASVNGRTVWGVGIAPSITTASLRAVVSAVNRAARA
NT seq
1800 nt
NT seq
+upstream
nt +downstream
nt
gtgacttcccatcccgacgccttcagctcgtcccgcagcatcgtcaaacccgccggcccg
cccggccccggacagcccgcctggaacccccagcgcggctcctcgatgccggtcaaccgg
taccggccgttcgccgaggaggtcgagcccatccggctgcccgaccgcacctggcccgac
aaggtcatcgaccgtgccccgctgtggtgcgcggtggacctgcgcgacggcaaccaggcg
ctgatcgacccgatgagcccggcccgcaagcgccgcatgttcgacctgctggtccgcatg
ggctacaaggagatcgaggtcggcttcccgtcggccagccagaccgatttcgacttcgtc
cgcgagatcatcaccgagggcgccattcccgacgacgtcaccattcaggtgctgacccag
tgccggccggaactgatcgagcgcaccttcgccgcgtgccagggcgcgccgcaggccatc
gtgcacttctacaactcgacgtcaatcctgcagcggcgcgtggtatttcgcgccgaccgg
gccgcggtgcaggagatcgccgtggccggcgcccgcaagtgcgtcgaggaggccgccaag
taccccgagacgcagtggcggttcgagtactcgccggagtcctacaccggaaccgaactg
gagtacgccaagcaggtgtgcgacgcggtcggcgaaatcataaggcccacaacggaaaac
ccgatcatcttcaacctgcccgccacggtggagatggccacccccaacgtgtacgccgac
tccatcgagtggatgagccgcaatctggcccgccgcgactccgtcatcctgagcctgcac
ccgcacaacgaccgcggaaccgccgtcgccgcagcggaattgggctatgcggccggcgcc
gaccggatcgagggctgcctgttcggcaacggcgaacgcaccggcaacgtgtgcctggtg
acgctggggctgaacctgttctcccgcggcgtggacccgcagatcgacttctccaacatc
gacgagatccgccgcacggtggagtactgcaatcagctgccggtgcacgagcggcacccc
tacggcggcgacctggtctacaccgcgttctccggcagccaccaggacgccatcaacaag
ggcctggaccagatgaagatcgacgccgacgccgccgacaccgacgtcgaggacatgctc
tggcaggtgccgtatctgccgatcgaccccaaggacgtcgggcgcacctacgaggcggtg
atccgggtgaactcgcagtccggcaagggcggggtggcctacatcatgaaggccgatcac
ggcctggccctgccgcgccggctgcagatcgagttctcccaggtgatccagaagatcagc
gagggcgagggcggcgaggtcagccccaaggagatgtgggacgcgttcttcgaggagtac
ctggccccggtgtggccgctggagcgggtcaagcagcgcgtcgacgcctccgacgaggac
agcggcgtcaccagcatctccgcgacggtcaagatcaacggggagcagaccgagatcaac
gggaccggcaacggcccgctggccgcgttcgtgcacgcgctcgccggggtcgggttcgac
gtggcggtgctggactactccgagcacgccatgagttcgggcgacgacgcgcaggccgcc
gcgtatgtggaggcgtcggtcaacggtcggacggtgtggggtgtcggcatcgccccgtcc
atcaccaccgcctcgttgcgcgcggtggtgtcggcggtcaaccgcgccgcccgcgcctga
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