Mycobacterium avium subsp. paratuberculosis E93: RE97_12070
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Entry
RE97_12070 CDS
T03847
Name
(GenBank) peptide synthetase
Organism
mavu
Mycobacterium avium subsp. paratuberculosis E93
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Condensation
AMP-binding
PP-binding
AMP-binding_C
Thioesterase
Methyltransf_12
Methyltransf_23
Methyltransf_25
Methyltransf_11
DUF5852
NodS
Abhydrolase_1
Abhydrolase_3
Motif
Other DBs
NCBI-ProteinID:
AJK79848
LinkDB
All DBs
Position
complement(2631950..2651104)
Genome browser
AA seq
6384 aa
AA seq
DB search
MKRGDRAYPVTRGQLDIWLAEQTGHLDVAWQLGVLVRIDGAIDPALLHQTMRHVVGEAES
LRASFFEADGQVFQKAVEYSDVDLTFYDLSGSSDPEREVREMTASIQRTPMPLTGPMIKF
ALFRTGSAEYYWFTTCHHIAIDGMGIALVGRRIAAVYTALASGKPIPPAFFGSLQDLVGG
ELEYEASAKFLEDKDYWLAHRPGDGTAGHPPRPADDGRDPYSPSPPVQLDESVIGSVKEL
SKALGIRRSSVLTAACALLVRGWCADGSDEVVLDFPVSRRVDPKSKTHPGMLAGVVPLVL
HAPAAATFADFCRHVDQRSREALRHQQFPTRTLDGEGDFSGPRQAPNRVVVNFVPARLTL
SLADVPATATYTSFGPVGHFGLFFLGFGDQQFLSTVGTGQPLANFDATDLAERLQRILAA
MAADPARLLSSLDVLRDPEHAQLEALGNTAVLTRTPGPAVSVPELFATQVARAPQDVALV
CEGRSLTYRQLDEASNRLAHLLAGLGAGPGQSVALLFSRSAEAVASILAVLKTGAAYLPI
DPAAPETRIGFMLADAKPVAALSTAELAGRLEGHGMTVIDVNDPRIQDRPATALPVPAAD
GVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLDAGLPPAGVWSQCHSYAFDVSVWEIFGA
LLRGGRLVVVPEDVTRAPEELHDVLVNEQVSVLTQTPSAVAMLSPQGLESVSLVVVGEAC
PAEVVDRWSPGRVMVNAYGPTETTMCVAISAPLAPGMGSPPIGVPVDGAGLFVLDAWLRP
VPPGVVGELYVGGAGVACGYWRRGGLTASWFVACPFGAPGARMYRTGDLVCWRSDGQLDY
RGRADEQVKVRGYRIELGEVQAALAALDDVDQAVVIAREDRPGGKRLVGYITGTADPAEV
RTALAQRLPVYMVPAAVVALDAIPLTPNGKLDTRALPTPEYTGSRYRAPSNAVEETVAGI
YAHVLGVERVGVDDSFFDLGGDSISALQVVARARAAGLTCRPRDVFVEQTVARLARVVGS
GDRAAEVADEGVGPVPPTPIMRWLQAAERAGGATDQFNQTVLVQAPAGVTETEVAIVLQA
LVDRHAMLRLRVTDDGADGWSFEVPEAGSVQARDCLRSVDALSDEALLAARARLNPAAGT
MLAALWVEATGQLAVIIHHLAVDAVSWWILLEDLNIAWALHRAGQPVELAPAGTSFARWA
RLLDEHARDPEVVGQLDRWKTVTSTPAALPAPRPDVDTYASAGRLSVELDAETTAMLLGE
VPAAFHAGIHDILLIAFGLAWTEFLGEPGAPIGIDVEGHGRHEELGADIDLSRTVGWFTA
KYPVSLDVAGLRWPQVAAGDPALGPVLKRAKEQLRTLPEPLTYGLLRYLNTDVDLAGADP
PIAFNYLGRQGAASDSAADGWRISQDMSLLGAAAAVPMPLMHAVELNAGTIDTGAGPHLH
AEWTWAPSVLGAEQITRVSRLWFEALAGVCAHVRSGGGGGLTPSDIAPARLTQQQIDELQ
SRHRIADILPLTPLQQGLLFHSSTAQGNDGMDDMYAVQLDFTLTGPLDADRLREAVRTVV
HRHPHLAALFCDQYDEPVQIIPADPAVEWRYVELDGTGAADADDLIEQLCAAERAAVADL
AGQPVFRTALVRTGGDRHRFVLTSHHILLDGWSLPILLREIFAGYYGQRLPAAGSYRAFL
TWLAERDLDAARRAWGEVLSGFDTPTLVAPEGRLGQGRRGFEKSCVPEQTTRALGELARS
CHTTLSTVLQAAWAVVLTSLTGRHDVVFGTPRSRVGQLEVDDAEQMVGLLINTVPVRAEI
TATTTTAQLLAQLQNSHNDTLEHQHLALNEIHRVTGHDQLFDTLFVYENYPIDSGMTLGA
DGLAIAEFTNREYNHYPLTVEALPGPELGLHIEFDTDVFDTASIESLVQRLQRVLVAMST
DPDRRLSSLDLLDRGERELVLSTMSGAGVSAPIGVAPQLLAAAVAADPDAPAIVDGAREL
SYRELDDWSTRLARKLIQHGVGPEHAAGVAIERCAELVVAWWAVTKVGGVYAPVNLDHPV
ERIASVLDTVNAVCVLTCGTDEVAGAGPRPILRIDGLDLSGHSTEPITDADRRSPLRADD
TAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADARVLMVASPTFDASVGELLL
AAGSGAALIVAPPQVYAGEALTALLHNQRVGTAILTPTVISTLDRGRLDGLHTLVAVGEA
CLPELVDGWAPGRQMFNGYGPSETTIWVTCARLTAGHPVRIGAPIPGVCARVLDGWLKPV
PVGVVGELYLSGPALGHGYLGRVDLTAERFVANPFGGPGERMYRTGDLVRWTPEGTLDYL
GRADNQIKLRGQRIELGEIENTLLACPQVTQAAVTVQDSAAGSQLVAYVTLDHGPSDADV
RHDTDDADDVAQWRHLYDDLYGADLAATFGEDFRGWNSSYTGEPIPLQEMAEWRSATVDR
IMSLRPRRVLEIGAGSGLLLSQIAPRCDRYVATDFSAVAIDNLARSMEQLQLPWRDRVEL
LTQPAHVTDGLPPGHFDTIVINSVVQYFPNAGYLADVIDNALELLAPGGSLFIGDVRNHA
LQGAFQTGIALARGGGADAAEIRQRVRHAMLGETELLLAPEFFTNWADSRPAAAGLDIQL
KRGLSDNELNRYRYDVVIHKAPAPVRSVAAAPTWSWTDCTDCAGLRDQLAARRPAVVRVT
DIPQAGVIDDVRVEAALAAGLPVADALAAAGSDTAAAVAEELHRVGEATGYRVAVTWGAQ
PGTLSAVFVQDGDQAAEPLTDLYLPPAGARQRTRHANDPRANTKIAQVRERLNAWLPEYM
VPTHIVALDEFPMTTSGKLDRKALPAPDYQDADRYRAPSTAVEEILVGIYGQVLGLERVG
VDDSFFDLGGDSLSAMRLIAAVNASLNTDLGVRTVFEAPTAAELALRVGSEADRPEPLVA
GERPAVIPLSFAQTRLWFIDQFQGPSPMYNITVALRLSGRLDADALRAALADVVARHESL
RTVFATADGTPQQVVIPADRIGFACDVVDARGWPEDRLREAMSAAARYTFDLSAESPLHT
ELFARGDDEHVLVVAVHHIAADGWSITPFARDLGVAYASRCAGRDPDWAPLPVQYADYTL
WQRAHLGDVDDPGSRIAAQLDFWTDALAGLPERLQLPTDRPYPAVADHRGARLAVDWPAE
LQQQLRRVAREHDATSFMVVQAAFAALLAKVSASSDVAVGFPIAGRPEPVLDELIGFFVN
TLVLRVDLNELGGDPTFAELLAQVRRRSLAAFEHQDVPFELLVERLNPTRSMSHHPLVQV
LLGWENFPGEVTAPAAGLALGDLQVTPMPLHTNTARMDLTFSLAERFTESGQRAGIAVTA
EYRTDVFDGRTVEGLIERLQRLLTAVTADPQRRLSAVDLLDANEHARLEKWGNTAVLARP
ATPVSVPARFAAQAARTPDAVALTCDGRSMTYRELDEAANRLAHFMIHHGAGPGERVALL
FPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIVAVTTAALAERLHGFDL
TVIDVADPAVATQPATAPPVPDPDDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDLRIGI
ELSPRQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPETVSRSPNEFHDLLVREHVTVLT
QTPSAVGLLRTDGLDGTALVIGAEPCPPELVDRWAPGRTMVNVYGPTETTMWACKSAPLT
AGSGFPPIGAPVTRAAFFVLDDWLRPVPPGVVGELYLAGDGVGVGYWRRPGLTAARFLAC
PFGEPGTRMYRTGDLVCWGPDGQLRYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAV
VVAREDNPGDKRLVGYVTGSVAPAKARAALAERLPAYMVPAAVVVLDSLPMTVNGKLDTR
ALPAPDYWHTGGYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRLITAI
NSALDTDLPVRTVFEAPTIAQLAPRIAQSAGGLAPLVAAGRPDVVPLSFAQNRLWFIDQS
QGPSPLYNMAAALRLRGRLDAGALGAALGDVVARHESLRTVFPSHQGTPRQLVVPAERAE
FGWDVIDATDWPADRLDDAVQDVTRHTFDLAAEIPIRAKLFAVSEDEHVLVIVVHHIAAD
GMSLTPLGVDLSQAYASRCAGHAPGWADLPVQYCDYTLWQRAQFGDLNDPDSRIGTQLAY
WEDALAGMPERLALPTDRPYPAAADQRGDSVAVDWPAELQQQVRRIAREHNATSFMVVQA
ALAVLLSKIGASSDVAVGFPIAGRRDPALDQLVGFFVNTLVLRIDLTGDPSFAELLALVQ
ARSLAAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGHDDPAAALALGDLDVT
SVPVHDQSARMDLVFSLAERWNPDGEFAGIGGRVEFRTDVFDAATIETLIERLRRVLEAM
TGDPGRPLSAVDLLDDAERAYLEEVGNTAILTRPASGRVSVPELFATQVARVPETVALVC
DDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAAILAVLKTGAAYLPID
PSAPQTRVEFMLGDAEPIAAVTTAELAQRLAGRPVTVVDVDDPGIDTLPNTALPLPDPDG
IAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPSPGVWSQCHSLAFDVSVWEIFGAL
LRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSAVAMLSPQGLESVSLVLAGEACP
PEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVDGAALFVLDESLRPV
PPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPGARMYRTGDLVRWRADGQLDYL
GRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYITGTADPAEAR
ARLGERLPAYMVPAAVLGLDAIPLTPNGKLDARALPAPDYAAGEYRAPESPTEEILAGIY
AEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPVRTVFEAPTVAALAPRIGE
GGSGLEPLTAGERPTVVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDGPLDTEALGAAL
GDVVARHESLRTLFAAPEGRPQQVVLPAERADFGWEVVDASGWSADQLDEAIGATARYTF
DLAAQIPLRAELFRLRDDRHVLVAVVHHIAADGMSITPLVRDLGAAYARRCDGRGPDWTP
LPVQYVDYTLWQRAQFGELADSGSRIAAQLAYWQDALAGMPERLALPTDRPYPLVADQRG
ATVEIDWPAELQQRIGDVAHRHNATSFMVIQTALTVLLAKLGANPDVAVGFPIAGRRDPA
LDDLVGFFVNTLVLRVDAAGDPSFTELLARVRTRSLEAFEHQDVPFEVLVERLNPTRSLT
HHPLVQVMLAWQNFAGQDTGPAAGLSLGDVEITPIPVDTHTARMDLTFSVGERWCESGEP
GGIGGTVEFRTDVFDPDSIQTLIGRLRRVLEAMTDDPTQSVWSVDLLDAGEHARLDTLGN
RAALTGPPPRFDSLPTLFAEQAARTPDAVALVCGGRRMTYRELDEAANRVAHLLRVRGAG
PGHTVALLFSRSAEAIVAILGVLKSGAAYLPIDPALPGERIGFMLADAAPMVAISTAELA
PRLHGQHDVPVIDVHDPAIEAAPSSALPPPGADDIAYLIYTSGTTGVPKGVAVSHRNVTQ
LLTADSGLPREGVWSQWHSLAFDVSVWEIFGALLHGGRLVVIPDSVVRSPDDFHALLLDE
QVSVLSQTPSAAGTLSPEGLEDLTLVVAGEACPAELVDRWAPGRTMINAYGPTEATVYTA
ISAPLQPGSPAGVPIGFPVPGAGLFVLDESLRPVPPGVVGELYVGGAGVACGYWRRGGLT
ASWFVACPFGAPGARMYRTGDLVCWRSDGQLDYRGRADEQVKVRGYRIELGEVQAALAGL
DDVEQAVVIAREDRPGGKRLVGYITGTADPAEVRTALAQRLPVYMVPAAVVALDAIPLTP
NGKLDTRALPTPEYTGSRYRAPSNAVEETVAGIYAHVLGVERVGVDDSFFDLGGDSISAM
RVITAINASLGVELAVRTLFEAPTVASLSWRAQTDTARGGQAEEIVPVQTLKEGTGAPLF
CIHAAGGLSWSYQVLGNHLDCPIIGIQQAEPQHAAPRSIREMAQSYADRIQETYPDGPYH
LVGWSFGGVVAHELAIELQRRGCAIARLVLLDAQPGLDGSVTAPDAALAEQHMMEEALRS
HLAAADHDQPHAHRQFNQLVREAGAEGMSRHKRLFDVLFGNARNNIERSKIHEPGVFLGD
VTIFSAVRDHEDRSAFLAENWRPYVAGDIVIHEIDCTHDEILNADVVDSYGQRLGQLLGA
QRRRELTPPQRFGADPGDDEPPVR
NT seq
19155 nt
NT seq
+upstream
nt +downstream
nt
gtgaaacgcggtgaccgggcatatccggtgacgcgaggccagctggacatctggctggcg
gagcagaccggccacttggatgtggcatggcagctgggcgtgctggtgcgcatcgacggc
gccatcgaccccgcgctgctgcaccagaccatgcgacacgtggtcggcgaggccgagagc
ctgcgcgccagcttcttcgaggccgacggccaggtcttccagaaggcggtcgaatactcc
gacgtcgacctgaccttctacgacctgagcggctcgtccgatccggagcgggaagtccgc
gagatgacggcgtcgatccagcgcaccccgatgccgctgaccggtccgatgatcaaattc
gctttgttccgaaccggttccgccgagtactactggttcaccacctgccatcacatcgcc
atcgacgggatgggcatcgcgctggtgggtcggcggatcgcggcggtctacacggcgctg
gcgtccggcaaaccgattccgcccgccttcttcggttcgctgcaggacctggtcggcggc
gagctggaatacgaggcatccgcgaaattccttgaggacaaggattattggcttgcgcac
cgtcccggcgacggcacggccggccatccgccgcggccggccgacgacgggcgagacccg
tattcgccctccccgccggtgcagttggacgagtcggtgatcggcagcgtcaaggagttg
tccaaggcgttgggcatccgtcggtcatcggtgctcaccgccgcctgtgcgttgttggtg
cgcggatggtgcgccgacggctccgacgaggtggtgctcgacttcccggtcagccggcgg
gtcgatcccaagtcgaagacgcatcccggcatgctggccggggtggtgccgctggtgctg
cacgccccggcggccgccacgttcgccgacttctgtcggcatgtcgatcagcgctcgcga
gaagcgttgcggcatcagcaattccccacccgcacgctggacggggaaggcgacttcagc
gggccgaggcaggcgccgaaccgggtcgtcgtcaacttcgtcccggcgcgtctcaccctc
agcctggccgacgtgccggccaccgcgacgtacaccagcttcggcccggtggggcacttc
gggctgttcttcctgggattcggtgaccagcaattcctgagcacggtcggcaccgggcag
ccgttggcgaacttcgacgcgacggacctggcggagcgattgcaacgcatcctggcggcc
atggccgccgacccggcccggctgctgtcgtcgttggatgtgctgcgcgaccccgagcac
gcgcagctggaagcgctcggcaacacggcggtcctgacccggacgccgggcccggcggtg
tcggtgccggagctcttcgcgacacaagtggcccgggcgccgcaggacgtggcgctggtg
tgcgaaggccgttcgctgacgtaccggcagctggatgaggcgtcgaacaggttggcgcat
ttgctggccggcctgggcgcgggcccgggacagtctgtggcgctgctgttttcgcggtcc
gccgaggcggttgcgtcgattctggcggtgctcaagaccggggcggcctatctgccgatc
gacccggccgcgccggagactcggatcgggttcatgctcgccgacgccaaacccgttgcg
gcgctgagcaccgcggagctggccggccggctcgagggccacggcatgacggtgatcgac
gtcaacgatccccgtatccaggaccggcccgccaccgcgttgccggtgcccgcggccgac
ggtgtcgcctatgtcatctacacgtcgggtaccacgggtgtgcccaaaggtgttgcggtc
acgcaccgcaacgtgacgcagttgttggggtcgctggacgcgggcttgccgccggccggg
gtctggtcgcagtgccactcgtatgcgttcgatgtgtcggtgtgggagatcttcggcgcg
ctgctgcggggcgggcgcctggtggtggtgcccgaagacgtcacccgcgcgcccgaagag
ctgcacgacgtgctggtcaatgagcaggtctcggtgttgacgcagacgccgtcggcggtg
gcgatgctctcgccgcaggggttggagtcggtgtcgttggtggtggtgggggaggcctgc
ccggctgaggtggtggatcgttggtcgccggggcgggtgatggtcaacgcctacggcccc
accgagacgacgatgtgcgtggccattagcgcgccgctggccccgggtatggggtcaccg
ccgatcggtgtgccggtggatggtgcggggttgtttgtgctggacgcgtggttgcggccg
gtgccgccgggggtggtcggcgagttgtatgtcggcggcgccggggtggcctgcggctac
tggcggcgcggcgggctgaccgcctcgtggtttgtggcgtgtccgttcggggcgcccggt
gcgcggatgtatcgcaccggggatctggtgtgttggcgttccgatgggcagttggactat
cggggtcgcgccgacgagcaggtcaaggttcgcgggtatcggatcgagctcggtgaggtg
caggcggcgctggcggcattggacgatgtggaccaggcggtggtgatcgcccgtgaggac
cggcctggcggcaagcggctggtcggctacatcaccggtaccgccgacccggccgaggtg
cgcaccgcgttggcccaacggctgccggtgtacatggtgccggccgcggtggtggcgctg
gacgcaatcccgttgacgcccaacggaaaactcgacacccgcgccctacccacacccgaa
tacacgggcagccgctaccgggcgccgtccaacgccgtcgaggagaccgtggccggcatc
tacgcccatgtgctcggtgtcgaacgggtcggcgtcgacgactccttcttcgacctcggc
ggcgacagcatctcggcgctgcaggtggtggcccgcgcccgtgccgccgggctgacttgc
cggccgcgagacgttttcgtcgagcagaccgtcgcccggctggcccgggtggtcggctcc
ggcgaccgggcggccgaggtggccgacgagggcgtcggccccgtgccgcccaccccgatc
atgcggtggctgcaggccgccgaacgggccggcggggccactgaccagttcaaccagacc
gtcctggtgcaagcgcccgcgggtgtgaccgagaccgaggtcgcaatcgtgttgcaggcg
ttggtagatcggcacgccatgctgcggttgcgggtcaccgacgacggcgccgacggctgg
tcgttcgaggtgcccgaggccgggtcggtgcaagcccgcgactgcctgcggtcggtggac
gcgctgtccgacgaggcgctgctggcggcccgggcgcggctgaacccggccgccgggacg
atgctcgccgcgttgtgggtggaggccaccggccagctggcggtgatcatccaccacctg
gccgtggacgcggtgtcgtggtggatcctgttggaggacctcaacattgcctgggccctg
caccgcgccggccagccggtggagctggcgccggcgggcacgtcgttcgcccggtgggcc
cgactgctcgacgagcacgcacgcgaccccgaggtagtcggccagctcgaccgctggaag
acggtcacctccacaccggccgcgctgccggcaccgcgacccgacgtggacacctacgcc
agcgccggtcgcctgtcggtggagctggacgccgagacgaccgcgatgctgctcggtgag
gtgccggcggcgttccacgccggcatccacgacatcctgctgatcgcgttcggcctggct
tggacggaattcctgggcgagcccggcgctccgatcggcatcgacgtggagggccacggc
cgccacgaggaactcggcgcggatatcgacctgtcccgcaccgtcggctggttcaccgcc
aaatacccggtgtcgctggacgtcgccgggttgcgctggccgcaggtggccgccggcgac
ccggcgctgggccccgtcctcaaacgggccaaggagcagctgcgcaccctgccggaaccg
ctgacctacgggctgctgcgttacctcaacaccgacgtcgacctggccggggccgacccg
ccgatcgcgttcaactacctgggacgccaaggcgccgcgtctgattcggcggccgacggg
tggcggatcagccaggacatgtcgctgctcggcgccgccgcggcggtgcccatgccgctg
atgcacgccgtcgagctcaacgccggcaccatcgacaccggcgccggcccgcacctgcac
gccgaatggacttgggcgccttcggttctcggcgcggagcagatcacccgggtgagccgg
ctgtggttcgaggcgctggccggtgtctgcgcgcacgtgcgctccggcggcggcggcggt
ctcaccccgtcggacatcgccccggcccggctgacccagcagcagatcgacgagctgcaa
agccggcaccgcatcgccgacatcctgccgctgaccccgctgcagcagggactgctcttc
cactccagcaccgcgcagggcaacgacggcatggacgacatgtacgcggtgcaattggat
ttcaccctcaccggccccctcgacgccgaccggctgcgcgaggcggtgcgcaccgtcgtc
caccggcatccccacctggcggccctgttctgcgaccagtacgacgaaccggtgcagatc
atccccgccgaccccgccgtcgagtggcgctacgtcgagctcgacggtacgggcgcggcc
gatgccgacgacctgatcgagcagctgtgcgccgccgaacgcgccgcggtggccgatctg
gccggccagccggtattccgcaccgcgctggtgcgcaccggaggcgaccggcaccggttc
gtgctgaccagccaccacatcctgctcgacggctggtcgctgccgatcctgctgcgcgag
atcttcgccggctactacgggcagcggctgcccgccgccggctcctaccgggccttcctc
acctggctggccgagcgcgacctcgacgccgcccgccgggcctggggcgaggtgctgtcc
ggtttcgacacgcccaccctggtcgccccggagggccggttggggcagggccgccgcggc
ttcgaaaagtcttgtgtccctgagcaaaccacccgggcgctgggcgagctggcacgctcc
tgccacaccacgctgagcaccgtgctgcaggcggcctgggcggtggtgctgacctcgctg
accggccggcacgacgtcgtcttcggtaccccgcgctcgcgggtcggccagctcgaggtc
gacgacgccgaacagatggtgggcctgctgatcaacacggtgccggtgcgcgccgagatc
accgcgaccaccaccaccgcgcagctgctggcgcagctgcagaacagccacaacgacacg
ctcgagcaccagcacctggcgctcaacgagattcaccgcgtcaccgggcacgaccaactc
ttcgacacgctgttcgtctacgagaactacccgatcgacagcggcatgacgttgggcgcg
gacgggctggccatcgccgagttcaccaaccgcgagtacaaccactacccgctgacggtg
gaagccctgcccggccccgaactcggcctgcacatcgagttcgacaccgacgtgttcgac
acggcgagcatcgaatccctggtgcagcgactgcagcgggtgctggtcgcgatgagcacc
gatccggaccgacggctgtcgtcgctcgacctgctggatcgcggcgagcgggagctggtg
ctgtcgacgatgtccggcgccggggtgagcgcaccgatcggggtggccccgcagctgctg
gccgcggcggtggccgccgacccggacgcgccggcgatcgtcgacggggcacgggagctg
tcctaccgcgaactcgacgactggtcaacacgcctggcgcgcaagctgatccagcacggt
gtgggccccgagcacgcggccggggtggcgatcgagcggtgcgccgagctggtggtcgcc
tggtgggcggtgaccaaggtcggcggcgtgtacgcgccggtgaatctggaccatccggtc
gagcggatcgcctcggtgctggacacggtgaacgcggtgtgcgtattgacctgcggcacc
gacgaagtcgccggcgcggggccgcggccgatcctgcggatcgacggtctcgacctgtcc
ggccactccaccgagccgatcaccgacgccgaccggcgctccccgctgcgcgccgacgac
accgcgtatctgatcttcacgtcgggttccaccggtgtccccaagggcgtcgcggtcagc
cacaccggcctgctgggctgggccgcggcccagcgcgagctgttcggcctgggcgcggac
gcgcgggtgctgatggtcgcctccccgaccttcgacgcatccgtcggggaattgttgctg
gccgcgggatccggggcggcgctgatcgtggcgccgccgcaggtgtacgccggtgaggcg
ctgaccgcgttgctgcacaaccagcgggtcggcacggccatcctgacccccaccgtgatc
tcgacgctggaccgtggccggctcgacgggctgcacaccctggtcgccgtcggggaggcc
tgcctgcctgagctggtcgacggctgggcgccgggccggcagatgttcaacggctacggc
cccagcgagaccaccatctgggtcacctgcgcgcggctgacggcgggccacccggtgcgc
atcggcgccccgatccccggcgtgtgcgcccgggtgctggacggctggctgaagcccgtc
ccggtcggcgtggtgggcgagctgtatctgagcgggccggcgctgggccacggctatctc
ggccgggtggacctgaccgcggaacggttcgtggccaacccctttggcggcccgggtgag
cgcatgtaccgcaccggcgacctggtgcgctggacgcccgaggggacgctggactacctc
ggccgcgccgacaaccagatcaaactgcgcgggcaacgcatcgagttgggcgaaatcgag
aacaccctgctggcctgcccgcaggtcacccaggcggccgtcaccgtgcaggacagcgcc
gccggctcccaactggtcgcctacgtgacactcgatcacgggccgagcgacgcggacgtc
cgccacgacaccgacgacgccgacgacgtcgcgcagtggcggcacctctacgacgacctg
tacggcgccgacctcgccgcgacgttcggcgaggacttccgcggctggaacagcagctac
accggcgagccgatcccgctgcaggaaatggccgaatggcgttccgccacagtcgatcgc
atcatgtcgctgcggccgcggcgggtgctggagatcggcgcgggctcggggctgctgttg
tcgcagatcgccccgcggtgcgaccgctatgtcgccaccgacttctccgcggtggcgatc
gacaacctggcccgatcgatggaacagctgcagctgccctggcgtgaccgggtcgagctg
ctgacccagcccgcccacgtcaccgacgggctgccgccgggccacttcgacaccatcgtc
atcaactcggtcgtccagtacttccccaacgccgggtatctggccgacgtcatcgacaac
gccctggagctgctggcccccggcgggtcgctgttcatcggcgacgtccgcaaccacgcc
ctgcagggcgccttccaaaccggcatcgccttggcccgcggcggcggcgccgatgcggcc
gagatccgccagcgtgtccgccacgccatgctcggtgaaaccgaattgcttttggcgcct
gagtttttcaccaactgggccgactctcgccccgcggcggccggactcgacatccagctc
aagcgcggactgtccgacaacgagctgaaccgctaccgctacgacgtcgtcatccacaag
gcgcccgcgccggtgcggtcggtggccgccgcgcccacctggtcgtggaccgactgcacc
gactgcgccggactgcgcgaccaactggcggcgcggcgccccgccgtcgtccgcgtcacc
gacattccgcaggccggggtgatcgacgacgtccgggtcgaagccgcgctggccgccggg
ttacccgtcgccgacgcgctcgccgcggccggatccgacaccgccgccgccgtcgccgag
gaactgcatcgcgtcggtgaggccaccggttaccgcgtcgccgtcacctggggcgcccaa
cccggcactcttagcgcggttttcgtgcaggacggcgaccaggccgccgagccgctgacc
gatctctacctgccgcccgccggggcccgacagcgcacccggcacgccaacgacccgcgc
gccaacaccaagatcgcccaggtgcgggagcggctgaacgcctggctgcccgaatacatg
gtgccgacgcacatcgtggcgctcgacgaattcccgatgaccacctcgggcaagctcgac
cgcaaggccctgccggcgccggactaccaggacgccgaccgctaccgcgccccgtccacc
gccgtcgaggagatcttggtcggcatctacggccaggtgctcgggctggagcgggtcggc
gtcgacgactcgttcttcgatctcggcggggattccctgtcggcgatgcggctgatcgcc
gccgtcaacgccagcctgaacaccgacctcggggtgcggaccgttttcgaggcgcccacc
gccgccgagttggcgctgcgcgtcggcagcgaggccgaccggcccgagccgctggtggcg
ggggagcgcccggcggtgatcccgctgtcgttcgcccaaacccggctgtggttcatcgac
cagttccagggcccgtcaccgatgtacaacatcactgtggcgttgcggctgtccgggcgg
ctggacgccgacgcgctgcgcgcggcgctggccgacgtggtggcccggcacgaaagcctg
cgcacggtcttcgcgaccgccgacggaaccccgcagcaggtggtcattcctgccgatcgg
atcggcttcgcctgcgacgtcgtcgacgcccgcggctggccggaagaccggctgcgcgag
gcgatgtcggccgcggcccgctacaccttcgacctgtcggccgaaagtccgctgcacacc
gagcttttcgcccgcggcgacgacgagcacgtgctggtcgtcgcggtgcaccacatcgcc
gcggacggctggtcgatcaccccgttcgcccgggacctcggggtcgcctatgcgagccgg
tgcgccggccgagaccccgactgggcgccgttgccggtgcagtacgccgactacacgctg
tggcagcgcgcgcatctgggcgacgtcgacgatccgggcagccggatcgccgcccagctg
gacttctggaccgacgcgctggccgggctgccggaacggctgcagctgcccaccgatcgg
ccctacccggcggtggccgaccaccgcggcgcgcggctggcggtggactggccggccgaa
ctgcagcaacagcttcgccgggtggcccgcgagcacgacgcgaccagcttcatggtggtc
caggccgcgttcgccgccctgctcgccaaggtcagcgccagttccgatgtggccgtgggc
tttccgatcgcgggccgccccgaacccgtgctcgacgagctgatcggtttcttcgtcaac
acgctggtgctgcgggtcgacctcaacgaactgggcggcgacccgaccttcgccgagctg
ctggcccaggtgcgccggcgcagcctggccgcgttcgagcaccaggacgtgccgttcgag
ttgctggtggagcggctcaacccgacccggagcatgtcccaccacccgctggtgcaggtg
ctgctcggctgggagaacttccccggcgaggtcaccgccccggccgccgggctggccctg
ggcgacctgcaggtcaccccgatgccgttgcacaccaacaccgcccgcatggacctgacc
ttctcgctggccgaacgcttcaccgagtcgggccagcgcgccggcatcgcggtgaccgcc
gaatatcgcaccgacgtgttcgacggcagaaccgtcgagggcctgatcgagcggttgcag
cggttgctgacggcggtcacggccgatccgcagcgccgcctgtcggcggtcgacctgctc
gacgccaacgagcacgcccggctcgaaaagtggggcaacaccgcggtgctggcccggccg
gccaccccggtgtcggtgcctgcccggttcgccgcgcaggcggcgcgcacccccgacgcg
gtcgcgctgacctgcgacggccggtccatgacctaccgcgaactcgacgaagcggctaac
cgcttggcgcacttcatgattcaccacggcgccggcccgggtgagcgggtggcgctgctg
ttcccccggtcggccgaggcgatcgtggccatcctggccgcgctcaagtcgggggcggcc
tatctgccgatcgaccctgcgctgccggcggcccgcgtcgagttcatgctcaccgacgcc
gccccgatcgtcgcggtcaccaccgccgcgctggctgagcggctgcacggtttcgacctc
accgtcatcgacgtcgccgaccccgccgtcgccacccagcccgcgacggcgccaccggtg
cccgaccccgacgacgtcgcccacatcatctacacctccggcaccaccggtgtgcccaaa
ggcgttgcggtgacgcaatacaacgtcgcccagctcttcgacgacctgcggatcggcatc
gagttgtcgccgcggcaggtgtggacccagttccattcctacgccttcgacttctcggtg
tgggagatctggggcgcgctgctgcacggcggccgcctggtggtggtgcccgaaacggtg
tcgcgctccccgaacgagttccacgacctgctcgttcgcgaacacgtcaccgtcctgacc
caaaccccgtcggccgtcggactgctgcggaccgacgggctggacggcaccgcgctggtg
atcggcgccgaaccctgcccgcccgagctggtggaccgctgggcgccgggccgcaccatg
gtcaacgtctacggccccaccgaaaccaccatgtgggcctgcaagagcgcaccactgacg
gccgggtcgggcttcccgccgatcggcgccccggtgacccgggcggcgttcttcgtgctc
gacgattggctgcgcccggtgccgcccggggtggtcggcgagctgtacctggccggcgac
ggcgtcggcgtcggctattggcgccgaccgggattgaccgccgcgcgcttcctggcctgc
ccgttcggcgaacccggaacccggatgtatcgcaccggcgacctggtgtgctggggcccg
gacgggcaactgcgctacctgggccgggccgacgagcaggtcaaggtccgcggctaccgc
atcgagctgggcgagatccaggcggcgctgtcggcgctggacggggtggagcaggccgtc
gtcgtcgcccgcgaggacaaccccggggacaagcgcctggtcggctacgtcaccggatcg
gtggccccggccaaggcgcgcgccgcgctggccgaacggctgcccgcctacatggtcccg
gccgcggtggtggtgctggattcgctgccgatgaccgtcaacggcaagctcgacacccgc
gcccttcccgcgcccgactactggcacaccggcgggtaccgcgcccccgaatcaccgacc
gaggagatcctggccggcatctacgccgaggtgctcggcgtgcagcgggtcggcgtcgac
gactcgttcttcgaccttggcggcgactcgctgaccacgatgcggctgatcaccgcgatc
aactccgcgctggacaccgacctgccggtgcgcaccgtcttcgaggcgcccaccatcgcc
cagctggcgccgcgcatcgcgcagagcgccggcgggctggcgccgctggtggccgccggg
cggccggacgtggtcccgctgtccttcgcgcagaaccggttgtggttcatcgaccaatcc
cagggcccctcaccgctgtacaacatggccgcggcgctgcggctgcggggcaggctcgac
gccggggcgctgggtgcggcgctgggcgacgtggtggcccggcacgagagcctgcgcacc
gtgttcccgtcgcaccaggggacgccccgccagctggtggtacccgccgagcgcgccgaa
ttcggttgggacgtcatcgatgccaccgattggccggccgaccggctggatgacgccgtc
caggacgtcacccgccacaccttcgacctggccgccgaaataccaatccgcgcaaagctt
ttcgcggtatccgaggacgagcacgtactggtgatcgtcgtccaccacatcgccgccgac
ggcatgtcgctgacgccgctgggcgtcgacctgagtcaggcgtacgccagccggtgcgcc
gggcatgccccgggatgggccgacttgccggtgcagtactgcgattacacgctgtggcag
cgcgcccagttcggtgatctcaacgaccccgacagccgcatcggcacccagctggcctac
tgggaggacgcgctggccggcatgcccgagcggctggcgctgcccaccgaccggccctac
ccggcggcggccgaccagcgcggcgacagcgtggcggtcgactggcccgccgagctgcag
cagcaggtgcgccggatcgcgcgtgaacacaacgccaccagcttcatggtggtgcaggcc
gccctggcggtgctgctgtccaagatcggcgcgagttccgatgtggcggtgggcttcccg
atcgccgggcggcgcgacccggcgctcgaccagctggtcggcttcttcgtcaacacgctg
gtgctgcggatcgacctgaccggcgaccccagcttcgccgagctgctggccctggttcag
gcccgcagcctggccgccttcgagcatcaggacgttccgttcgaggtgctggtggagcgg
ctcaacccgacccgcagcctgacgcatcacccgctggtgcaggtgatgctggcctggcag
aacttcgccgggcacgacgaccccgcggccgctttggcattgggtgacctcgacgtgacg
tcggtgccggtgcacgaccagtccgcccggatggacctggtgttctcgctggccgaacgc
tggaaccccgacggcgaattcgccggcatcggcgggcgggtggaattccgcaccgacgtg
ttcgacgcggccaccatcgagacgctgatcgaacggctgcggcgggtgctggaggcgatg
acgggcgatccgggccggccgctgtccgcggtggatctgctcgacgatgccgagcgcgct
tacctggaagaggttggcaacacggcgattttgacccggccggcgagcgggcgggtgtcg
gtgcccgaactgttcgccacccaggtggcccgggtgccggagacggtggcgctggtctgc
gacgacctgtcggtgacctaccggcagctcgacgaggcgtcgaaccggctggcgcatcgc
ctggccgcggccggcgccggcccgggacagactgtggcactgctgttttcgcgatccgcc
gaggcggtcgccgccatcctcgcggtgctcaagacgggggcggcctacctgcccatcgac
ccgtcggccccgcagacccgcgtcgagttcatgctcggcgacgccgaaccgatcgccgcc
gtcaccaccgccgagctggcgcagcggctcgccggccgccccgtgaccgtcgtcgacgtc
gacgatccgggcatcgataccctgccgaacaccgcgctgccgctgcccgacccggacggc
atcgcgtacctgatctacacctccggcaccaccggtgcgcccaaaggcgttgcggtcact
caccacaacgtgacccagctgctggggtcgctggacgccggcctgccgtcgccgggggtg
tggtcgcaatgtcactcgctggccttcgacgtgtcggtgtgggagatcttcggcgcgctg
ctgcgcggcggacgcgtggtggtgatgcccgaggcggtggcccgctcaccgcacgacctg
cacgacgccctgatcgcccggcacgtcaccgtgctgacccaaaccccgtccgcggtggcg
atgctctccccgcaggggttggagtcggtgtcgctggtgctggccggcgaggcctgcccg
cccgaggtggtggaccaatgggcgcccggacgggtgatggtcaacggctacggcccgacc
gaaaccagcatgtgcgtgagcatcagcgccccgctgaccgcgggatccggcataccgccg
atcgggtcgccggtcgatggggcggcgctgttcgtgctcgacgaatcgctgcggccggtg
ccgcccggcgtggtgggcgaactctacgtcgccggatccggtgtggccgcagggtatctc
gggcgaccgtccctgaccgcggcccgcttcgtggcgtgcccgttcggggcgccgggtgcg
cggatgtatcgcaccggggacctggtgcgctggcgcgccgacgggcagctggactacctg
ggccgggccgacgagcaggtcaaggtccgcggctaccgcatcgagctgggcgagatccag
gcggcgctgtcggcgctggacggggtggagcaggccgtcgtcgtcgcccgcgaggacaat
cccggggacaagcggctggtcggctacatcaccggcaccgccgacccggccgaggcccgc
gcgcgcctgggcgagcggctgcccgcctacatggtccccgccgccgtgctggggctcgac
gcaatcccgttgacccccaacggcaaactcgacgcccgcgccctgcccgcacccgactac
gccgccggcgagtaccgcgcccccgaatcaccgaccgaggagatcctggccggcatctac
gccgaggtgctgggcgtgcagcgggtcggggtcgacgactccttcttcgacctgggcggc
gacagcatctcggcgatgcgcctgatcgcggccgtcaacgccgccctgaacgccgacctg
ccggtgcgcaccgtgttcgaggcgcccacggtcgccgcgctagcgccccggatcggggag
ggcggcagcggactcgagccgttgacggccggtgagcggcccacggtggtgccgttgtcg
ttcgcgcagaaccggctgtggttcctggatcaattgcagggcccctcaccggtttacaac
atggcggccgcgctgcggctggacggcccgctggacaccgaggcgctgggcgcggcgctg
ggcgacgtggtggcccggcacgagagcctgcgcaccctgttcgccgcccccgaggggcga
ccccagcaggtggtgctgcccgccgagcgggccgacttcgggtgggaggtcgtcgacgcc
agcggctggtcggcagaccaactggacgaggcgatcggcgccaccgcccgctacaccttc
gaccttgccgcccaaatcccgctgcgcgcagagcttttccgtctccgcgacgaccggcac
gtgctggtggccgtggtgcaccacatcgccgccgacggcatgtccatcaccccgctggtg
cgtgatctcggtgcggcctatgcccgccggtgcgacgggcgcggccccgactggacgccg
ctgccggtgcagtacgtcgactacacgctgtggcagcgcgcccagttcggcgagctggcc
gacagtggcagccgcatcgccgcccagctggcctactggcaggacgcgctggccggcatg
cccgagcggctggcgctgcccaccgaccggccctatccgctggtggccgatcagcgcggc
gccactgtggaaatcgactggccggccgagctgcagcagcgaatcggcgacgtggcccac
cggcacaacgccaccagcttcatggtgatccagaccgccctgaccgtgctgctggccaag
ctcggcgccaatcccgacgtggcggtgggcttcccgatcgcggggcggcgcgacccggcg
ctggacgacctggtcgggttcttcgtgaacaccctggtgctgcgggtggacgcggccggc
gatcccagcttcaccgagctgctggctcgggtccgcacccgcagcctggaggccttcgag
caccaggatgtgccgttcgaggtgctggtggagcggctcaacccgacccgcagcctcacc
catcacccgctggtgcaggtgatgctggcctggcagaacttcgccgggcaggacaccggc
ccggccgcggggctgtccctcggcgatgtggagatcacgccgataccggtggacacccac
accgcgcggatggacctgaccttctccgtcggcgaacgctggtgcgagagcggcgaaccg
ggcgggatcggcggcacggtggaattccgcaccgacgtgttcgacccggacagcatccag
acgctgatcgggcggttgcgccgggtgctggaggcgatgaccgacgacccgacacaatcc
gtgtggtcggtggacctgctcgacgccggcgagcacgcccgcctcgacaccctgggcaac
cgggcggcgctgaccggacctccgccccggttcgattccctcccaacgcttttcgccgaa
caggccgcccgcaccccggacgccgtcgcgctggtctgcggcggccgccggatgacctac
cgggagctggacgaggccgccaaccgggtggcccacctgctgcgcgtgcggggggccggc
ccgggacacaccgtggcactgctgttttcccggtcggccgaggcgatcgtcgcgatcctg
ggggtgctcaagtcgggggcggcctacctgccgatcgacccggcgctgccgggcgagcgg
atcgggttcatgctggccgacgccgcgccgatggtcgcgatcagcaccgccgagctggcg
ccgcggctgcacggccagcacgacgtgccggtcatcgacgtgcacgaccccgcgatcgag
gccgcgccgtcgagcgcgctgccgccgccgggtgcggacgacatcgcctacctgatctac
acctcgggcaccaccggcgtgcccaaaggcgttgcggtgagccaccgcaacgtgacgcag
ctgctcaccgccgattccgggctgccgcgcgagggcgtgtggtcgcagtggcattcgctg
gccttcgacgtgtcggtgtgggagatcttcggcgccctgctgcacggcggccggctggtg
gtgatccccgactcggtggtgcgctcgccggacgacttccacgccctgctgctcgacgag
caggtcagcgtgctcagccagaccccgtcggcggccggcaccctctcacccgagggcctc
gaggacctcaccctggtggtcgccggcgaggcctgcccggccgagctggtcgaccgctgg
gccccgggccggacgatgatcaacgcctacggccccaccgaggccaccgtctacaccgcg
atcagcgcgccgctgcagcccgggtcaccggccggggtgccgatcggcttcccggtgccg
ggcgccggcctgttcgtgctcgacgaatcgctgcggccggtgccgccgggtgtggtgggt
gagctctatgtcggcggcgccggggtggcctgcggctactggcggcgcggcgggctgacc
gcctcgtggtttgtggcgtgtccgttcggggcgcccggtgcgcggatgtatcgcaccggg
gatctggtgtgttggcgttccgatgggcagttggactatcggggtcgcgccgacgagcag
gtcaaggttcgcgggtatcggatcgagctcggtgaggtgcaggcggcgctggccgggctg
gacgatgtcgagcaggcggtggtgatcgcccgtgaggaccggcctggcggcaagcggctg
gtcggctacatcaccggtaccgccgacccggccgaggtgcgcaccgcgttggcccaacgg
ctgccggtgtacatggtgccggccgcggtggtggcgctggacgcaatcccgttgacgccc
aacggaaaactcgacacccgcgccctacccacacccgaatacacgggcagccgctaccgg
gcgccgtccaacgccgtcgaggagaccgtggccggcatctacgcccatgtgctcggtgtc
gaacgggtcggcgtcgacgactccttcttcgacctcggcggcgacagcatctcggcgatg
cgggtgatcacggcgatcaacgccagcctgggcgtcgagctcgcggtccgcaccttgttc
gaggcgcccaccgtcgcaagcctgagctggcgggcgcagacggataccgctcgcggcgga
caagccgaagagatcgtgcccgtccagaccctgaaagaggggaccggcgcaccgctgttc
tgcatccatgccgccggcgggctcagttggtcatatcaggtgctcggcaatcatctggat
tgcccgatcatcgggattcaacaagccgaaccgcagcacgccgcgccgcggtcgattcgc
gagatggcgcaaagctacgccgacagaatccaggaaacctatcccgatggcccctaccat
ctcgtcggctggtcgttcggcggcgtcgtcgcccacgaactcgcgatcgagctgcagcgg
cgcgggtgcgcaatcgcacgccttgtcctcctcgacgctcaacccggtctcgacggcagc
gtcaccgcacccgacgctgccctggccgagcagcacatgatggaagaagccctgcggtcg
cacctggccgccgccgatcacgaccaaccgcatgcgcatcggcagttcaatcaactcgtc
cgtgaagccggagccgaaggcatgtctcgacacaaacgccttttcgatgtgcttttcggg
aatgcccgaaacaatatcgagcgcagcaagattcacgagcccggtgttttcctcggcgat
gtgaccatcttctccgcggtgcgtgatcacgaggatcgcagtgcgttcctcgccgagaat
tggcgtccatacgttgccggcgacatcgtcatccacgagatcgactgcacgcatgacgag
atcctcaatgccgatgtggtggattcgtacgggcagcgcctcgggcaactgctgggcgcg
caacgtcgccgggaactgaccccaccgcaacgattcggggcggaccccggcgacgacgag
ccgcccgtccggtga
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