Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2: BCG_3016c
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Entry
BCG_3016c CDS
T00463
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase leuB
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
mbb
Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2
Pathway
mbb00290
Valine, leucine and isoleucine biosynthesis
mbb00660
C5-Branched dibasic acid metabolism
mbb01100
Metabolic pathways
mbb01110
Biosynthesis of secondary metabolites
mbb01210
2-Oxocarboxylic acid metabolism
mbb01230
Biosynthesis of amino acids
Module
mbb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mbb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
BCG_3016c (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BCG_3016c (leuB)
Enzymes [BR:
mbb01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
BCG_3016c (leuB)
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GFIT
Motif
Pfam:
Iso_dh
IFRD
Motif
Other DBs
NCBI-ProteinID:
CAL73005
UniProt:
A1KMY9
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All DBs
Position
complement(3306945..3307955)
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AA seq
336 aa
AA seq
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MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN
VLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
NT seq
1011 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcgcgatcattgccggtgacgggatcgggcccgaggtaaccgccgaggcggtc
aaagtgctcgacgcggttgtgccgggcgtccagaaaaccagctatgacctgggtgcgcgg
cgctttcatgccaccggcgaggtgctgccggactcggtggtggccgagctgcgcaaccac
gacgcgatcctgctcggggcgatcggtgacccgtcggtgccaagcggcgtcttggagcgc
ggtctgttgctgcgactgcgcttcgagctggatcaccacatcaacctgcgtccggcccgg
ctgtatccgggggtggccagcccgctgtccggcaatcccggcatcgacttcgtggtggtg
cgcgagggcaccgagggaccctacaccggcaacggcggggcgattcgcgtcggcacgccc
aacgaggtggccaccgaagtcagcgtgaacaccgcgttcggtgtgcggcgtgtggttgcc
gacgcgttcgagcgggctcgacggcgtcgcaagcatctgacattggtgcacaaaaccaac
gtgttgaccctcgccgggggattgtggttgcggaccgtcgacgaggtcggcgaatgctac
ccggacgtcgaggtggcctaccagcacgtcgacgccgccaccatccacatgatcaccgac
ccgggtcgcttcgacgtgatcgtcaccgacaacctgttcggcgacatcatcaccgatctg
gccgcggcggtatgtggcggtatcggcttggcggccagtgggaatatcgacgcgacccgg
gccaacccgtcgatgttcgagccggtgcatggcagcgcgccggacatcgccggtcagggc
atcgccgacccgacggcggcgatcatgtcggtggcgttattgctgtcccaccttggcgaa
cacgacgcggctgcccgggtggaccgggccgtcgaggcccatttggccacgcgtggcagc
gaacggcttgccaccagcgatgtcggcgaacggattgccgccgcgctctag
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