Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2: BCG_3770
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Entry
BCG_3770 CDS
T00463
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase leuA
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mbb
Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2
Pathway
mbb00290
Valine, leucine and isoleucine biosynthesis
mbb00620
Pyruvate metabolism
mbb01100
Metabolic pathways
mbb01110
Biosynthesis of secondary metabolites
mbb01210
2-Oxocarboxylic acid metabolism
mbb01230
Biosynthesis of amino acids
Module
mbb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mbb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BCG_3770 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BCG_3770 (leuA)
Enzymes [BR:
mbb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BCG_3770 (leuA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CAL73760
UniProt:
A0A0H3MFG4
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All DBs
Position
4126856..4129360
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AA seq
834 aa
AA seq
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MTTSESPDAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRN
RTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQT
DFDFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAHRAIVHFYNSTSILQRRVV
FRANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIA
PTPERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG
FAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPV
HERHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGR
TYEAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEM
WDAFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVH
ALADVGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPA
QPGEAGRHASDPVTIASPAQPGEAGRHASDPVTIASPAQPGEAGRHASDPVTIASPAQPG
EAGRHASDPVTIASPAQPGEAGRHASDPVTIASPAQPGEAGRHASDPVTIASPAQPGEAG
RHASDPVTIASPAQPGEAGRHASDPVTIASPAQPGEAGRHASDPVTIASPAQPGEAGRHA
SDPVTIASPAQPGEAGRHASDPVTSKTVWGVGIAPSITTASLRAVVSAVNRAAR
NT seq
2505 nt
NT seq
+upstream
nt +downstream
nt
gtgacaacttctgaatcgcccgacgcctataccgagtcgtttggggcccacaccatcgtg
aaacccgccggcccacctcgcgtcggtcagccctcgtggaatccgcagcgagcctcgtcg
atgccggtcaaccgctaccggccgttcgccgaggaggtcgagcccatccggctgagaaac
cgcacgtggcctgatcgcgtcatcgatcgtgcgccgctgtggtgcgcggtcgacttacgc
gatggcaaccaggcgctgatcgacccgatgagcccggcccgcaagcgccgcatgttcgac
ctgctggtccggatgggctacaaggagattgaggtggggttcccctcggccagccagacc
gacttcgacttcgtcagagagatcatcgagcagggcgccattcccgacgacgtcaccatc
caggtgctcacccaatgccgtcccgagctgatcgagcgcaccttccaggcgtgttcgggc
gcacaccgggccatcgtgcacttctacaactcgacgtcaatcctgcagcgccgcgtggtc
tttcgcgccaaccgggctgaggtgcaggccatcgcgacagatggggcgcgcaagtgcgtc
gagcaggccgccaaatacccgggcacgcagtggcgattcgagtactccccggagtcctac
accggcaccgaactggaatacgccaaacaggtgtgcgacgccgtcggcgaggtcattgcg
ccgacgccggagcgcccgatcatcttcaacctgcccgccacggtggagatgacgacgccc
aatgtctacgccgactcgatcgagtggatgagccgcaacctagccaaccgggagtcggtc
atcctgagcctgcacccgcacaatgaccgcggaaccgccgtcgccgcagcggaattgggt
ttcgcggccggggctgatcggatcgagggctgcctgttcggcaacggcgagcgcaccggc
aacgtgtgcctggtcacgctgggactcaacctgttctcccgaggtgtggacccgcagatc
gacttctccaatattgacgagatccggcgcacggtggagtactgcaaccagctgccggtg
cacgaacgtcacccctatggcggcgacctggtgtacaccgcgttctccggtagccaccag
gacgccatcaacaagggcctagacgcgatgaagctggatgcggatgccgccgactgtgac
gtcgacgacatgctgtggcaggtgccgtatctgcccatcgacccgcgcgatgtcgggcgc
acctacgaggcggtgatccgggtcaactcgcagtccggcaagggcggcgtggcctacatc
atgaagaccgaccacggcctttccctgccgcggcggctgcagatcgagttttcccaggta
atccagaagatcgcagagggtacagcaggcgagggtggcgaggtctcgcccaaggagatg
tgggatgcgttcgccgaggagtatctggccccggtgcggcctttggagcggataaggcaa
catgtggacgctgccgacgacgacggcggcacgaccagcatcacggcgaccgtcaagatc
aacggcgtggagaccgagatcagcgggtccggtaacggtccgttggccgcgttcgtccat
gcgctggccgatgtcgggtttgacgtggccgtgctggactactacgagcacgcgatgagc
gccggcgacgacgctcaggccgccgcgtatgtggaggcctccgtgacgatcgcgagcccg
gcgcagccgggcgaagcgggtcggcacgcatcggaccccgtgacgatcgcgagcccggcg
cagccgggcgaagcgggtcggcacgcatcggaccccgtgacgatcgcgagcccggcgcag
ccgggcgaagcgggtcggcacgcatcggaccccgtgacgatcgcgagcccggcgcagccg
ggcgaagcgggtcggcacgcatcggaccccgtgacgatcgcgagcccggcgcagccgggc
gaagcgggtcggcacgcatcggaccccgtgacgatcgcgagcccggcgcagccgggcgaa
gcgggtcggcacgcatcggaccccgtgacgatcgcgagcccggcgcagccgggcgaagcg
ggtcggcacgcatcggaccccgtgacgatcgcgagcccggcgcagccgggcgaagcgggt
cggcacgcatcggaccccgtgacgatcgcgagcccggcgcagccgggcgaagcgggtcgg
cacgcatcggaccccgtgacgatcgcgagcccggcgcagccgggcgaagcgggtcggcac
gcatcggaccccgtgacgatcgcgagcccggcgcagccgggcgaagcgggtcggcacgca
tcggaccccgtgacgatcgcgagcccggcgcagccgggcgaagcgggtcggcacgcatcg
gaccccgtgacgagtaagacggtgtggggtgtcggtatcgcaccgtcaatcaccaccgcg
tcgctgcgcgccgtggtgtcggcggtcaaccgggcggcacgctag
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