KEGG   Moschus berezovskii (Chinese forest musk deer): 129540556
Entry
129540556         CDS       T09065                                 
Symbol
NOS2
Name
(RefSeq) nitric oxide synthase, inducible isoform X1
  KO
K13241  nitric-oxide synthase, inducible [EC:1.14.13.39]
Organism
mbez  Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez00220  Arginine biosynthesis
mbez00330  Arginine and proline metabolism
mbez01100  Metabolic pathways
mbez04020  Calcium signaling pathway
mbez04066  HIF-1 signaling pathway
mbez04146  Peroxisome
mbez04371  Apelin signaling pathway
mbez04926  Relaxin signaling pathway
mbez05010  Alzheimer disease
mbez05014  Amyotrophic lateral sclerosis
mbez05022  Pathways of neurodegeneration - multiple diseases
mbez05133  Pertussis
mbez05140  Leishmaniasis
mbez05142  Chagas disease
mbez05145  Toxoplasmosis
mbez05146  Amoebiasis
mbez05152  Tuberculosis
mbez05200  Pathways in cancer
mbez05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:mbez00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    129540556 (NOS2)
   00330 Arginine and proline metabolism
    129540556 (NOS2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    129540556 (NOS2)
   04066 HIF-1 signaling pathway
    129540556 (NOS2)
   04020 Calcium signaling pathway
    129540556 (NOS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    129540556 (NOS2)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    129540556 (NOS2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129540556 (NOS2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    129540556 (NOS2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    129540556 (NOS2)
   05152 Tuberculosis
    129540556 (NOS2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    129540556 (NOS2)
   05145 Toxoplasmosis
    129540556 (NOS2)
   05140 Leishmaniasis
    129540556 (NOS2)
   05142 Chagas disease
    129540556 (NOS2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129540556 (NOS2)
   05014 Amyotrophic lateral sclerosis
    129540556 (NOS2)
   05022 Pathways of neurodegeneration - multiple diseases
    129540556 (NOS2)
Enzymes [BR:mbez01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     129540556 (NOS2)
SSDB
Motif
Pfam: NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 DUF2478
Other DBs
NCBI-GeneID: 129540556
NCBI-ProteinID: XP_055257629
LinkDB
Position
Unknown
AA seq 1157 aa
MACPWQFLFKIKSQKMDLNTELDINNNVEKGYQPPSSPVTQDDPKRHSPGKHGNESPQPL
TGTVKTSPESLGKLDTPPSACPRHVRVKNWGSGVTFQDTLHQKAKGDLSCKSKSCLASIM
NPKSLTIGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ
LTGDELIFAAKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHVCRHVRYATNNGNI
RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPASVEFTQLCIDLGWKPKYS
RFDVLPLVLQADGRDPELFEIPPDLVLEVPMEHPRYEWFRELELKWYALPAVANMLLEVG
GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVVEINI
AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM
LNYVLSPFYYYQVEAWKTHVWQDKRRRPQKREIRFKVLVKAVFFASVLMHKAMASRVRAT
ILFATETGRSETLAQDLGALFSCAFNPKVLCMDQYRLSQLEEEQLLLVVSSTFGNGDSPG
NGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLAPTGEGD
ELSGQEEAFRSWAVQTFKAACETFDVSGKHHIEIPKLYTSNVTWDPHHYRLVQDSEPLDL
NKALSGMHAKHVFTMRLKSQQNLQSPKSSRTTLLVELSCEGSQAPSYLPGEHLGVFPCNQ
PALVQGILERIVDGPAPHQPMCLETLCENGSYWVKDKRLPPCSLSQALTYFLDITTPPTQ
LLLRKLAQLATEEAERQRLETLCQPSDYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQL
PILKPRYYSISSSRDLTPTEIHLTVAVLTYRTQDGQGPLHHGVCSTWLSSLKPQDPVPCF
VRSASGFQLPEDRSRPCILIGPGTGIAPFRSFWQQRLHEAEHKGLQGGRMTLVFGCRRPE
EDHLYWEEMLEMARKGVLHEVHTAYSRLPDQPKVYVQDILRQRLAGEVLRVLHEEQGHLY
VCGDVRMARDVAHTLKQLVATALSLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEMKKDG
AAGLPSDPNAPGAHRRS
NT seq 3474 nt   +upstreamnt  +downstreamnt
atggcctgtccctggcagtttctgttcaaaatcaaatcccagaagatggacttgaatacg
gaactggatatcaacaacaacgtggaaaaaggctaccagcctccgtccagtccagtgaca
caggatgaccccaaacgtcacagcccgggcaagcacgggaatgagtctccccagcccctc
acggggacggtaaagacatctccagagtccctgggcaagctggacacacccccgtcagcc
tgtccacggcatgtgagggtcaaaaactggggcagcggagtgactttccaagacacgctt
caccagaaggccaaaggggatctctcttgcaagtccaagtcttgcctggcatccatcatg
aaccccaaaagtttgaccataggaccccgggacaagccaacccccccagacgagcttcta
cctcaagctatcgaatttgtcaaccagtattacggctccttcaaagaggcaaaaatagag
gaacatctggccagggtggaagcagtaacaaaggagatagaaacaacaggaacgtaccag
ctgacgggagatgagctcatctttgccgccaagcaggcctggcgcaacgccccccgctgc
atcgggaggatccagtggtcgaacctgcaggtctttgatgcccggagctgttccacggcc
caggaaatgttcgaacatgtctgcagacacgtgcgttatgccaccaacaacggcaacatc
aggtcggccatcaccgtgttcccccagcggagcgatgggaaacacgacttccgggtctgg
aacgcccagctcatccgctatgccggctaccagatgccggatggcagcatcagaggggac
cccgccagcgtggagttcacacagctgtgcatcgacctgggatggaagcccaagtacagc
cgcttcgacgtgttgcctctagtcctgcaggctgacggccgcgacccagagctcttcgaa
atcccccctgaccttgtgctcgaggtgcccatggaacatcccaggtacgaatggttccgg
gagctggagctcaagtggtatgccctgccagctgtggccaatatgctgctcgaagtgggc
ggcctcgagttcccaggatgccccttcaatgggtggtacatgggcacggagattggagtc
cgggacttctgcgatgtccagcgatataacatcctggaggaagtgggcagaaggatgggc
ctggaaacacacaagctggcctcactctggaaggaccgggctgtcgttgagatcaacatt
gctgtgctccacagtttccagaagcagaatgtgaccatcatggaccaccactccgctgca
gagtccttcatgaagtacatgcagaatgagtaccgctcccgagggggctgcccggctgac
tggatttggctggtccccccgatttctggaagcatcacccccgtgttccaccaggagatg
ttaaattacgtcctgtcccctttctactactaccaggtggaagcctggaaaacccatgtc
tggcaggacaagaggcggaggccccagaaaagagagattcgattcaaagtcttggtcaaa
gctgtgttcttcgcctcggtgctgatgcataaggccatggcatcccgggtcagagccacg
atcctctttgcaacagagacggggagatcggaaacgctggcccaggacctcggggctttg
ttcagctgtgccttcaaccccaaggttctctgcatggatcagtaccggctgagtcaactg
gaagaggaacagctgctgctggtggtgagcagcacttttggcaacggagactcccccggc
aacggagagaaactgaagaagtccctctttatgctgaaagaactcaccaacaagttccgg
tacgccgtgtttggccttggctccagcatgtaccctcagttctgcgcctttgctcatgac
atcgaccagaagttgtcccagctgggggcttctcagcttgccccaaccggggaaggggat
gaactcagtgggcaggaggaggccttccgcagctgggccgtgcaaaccttcaaggccgcc
tgtgagacgtttgatgtcagtggcaagcaccacattgagatccccaagctctatacttcc
aatgtgacctgggacccacaccactacaggctcgtgcaggactcagagcctctggacctc
aacaaagccctgagcggtatgcacgccaagcatgtgttcaccatgaggctcaaatcgcag
cagaatctgcagagtccaaaatccagccgcaccaccctcctggtagaactctcctgtgag
ggcagccaagctccaagttacctgccgggagagcacctcggagttttcccatgcaaccag
ccggccctggtccaaggcatccttgagcgaatagtggatggccctgccccgcaccagccc
atgtgcctggagaccctctgtgagaatggcagctactgggtcaaggacaagcgactgcca
ccttgctcactcagccaggctctcacctatttcctggacatcaccaccccaccaacccag
ctgctgctccgaaagctggcccagctggccacagaagaggctgagaggcagaggctggag
accctatgccagccctcagattacaacaagtggaagttcaccaacagccccacattcctg
gaggtgctggaggagttcccgtccctgcgggtgtctgccagcttcctgctctcccagctc
cctattctgaagccccggtactactccatcagctcctccagggacctcacacccacggag
atccacctcactgtggctgtgctcacgtaccgcacccaagatggccaaggtcccctgcac
catggcgtctgcagcacgtggctcagcagcttgaagccccaagacccggtgccctgcttt
gtgcgaagtgccagcggcttccagcttccggaggaccgctcccgtccttgcatcctcatc
ggacccggcacgggcatcgcccccttccgcagtttctggcagcagcggctccatgaggct
gagcacaaagggctccagggcggccgcatgaccctggtgtttgggtgccgccgcccggaa
gaggaccacctctactgggaggagatgctggagatggcccgcaagggggtgctgcacgag
gtgcacacagcctattcccgcttgcctgaccaacccaaggtctatgttcaagacatcctg
cggcagcggctggcgggtgaggtgcttcgcgtgctccatgaggagcaaggccacctctat
gtctgcggggacgtgcgcatggcccgggacgtggcccacaccctgaagcagctggtggct
accgcactgagcctgaatgaggagcaggtggaggactatttcttccagctcaagagccag
aagcgctatcatgaagacatctttggtgctgtatttccctacgagatgaaaaaggatggg
gcagcagggctgcccagcgatcccaatgctccaggcgcccacaggagaagttaa

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