Moschus berezovskii (Chinese forest musk deer): 129547229
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Entry
129547229 CDS
T09065
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
mbez
Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez00562
Inositol phosphate metabolism
mbez01100
Metabolic pathways
mbez01521
EGFR tyrosine kinase inhibitor resistance
mbez04012
ErbB signaling pathway
mbez04014
Ras signaling pathway
mbez04020
Calcium signaling pathway
mbez04062
Chemokine signaling pathway
mbez04064
NF-kappa B signaling pathway
mbez04066
HIF-1 signaling pathway
mbez04070
Phosphatidylinositol signaling system
mbez04072
Phospholipase D signaling pathway
mbez04360
Axon guidance
mbez04370
VEGF signaling pathway
mbez04380
Osteoclast differentiation
mbez04611
Platelet activation
mbez04613
Neutrophil extracellular trap formation
mbez04625
C-type lectin receptor signaling pathway
mbez04650
Natural killer cell mediated cytotoxicity
mbez04662
B cell receptor signaling pathway
mbez04664
Fc epsilon RI signaling pathway
mbez04666
Fc gamma R-mediated phagocytosis
mbez04670
Leukocyte transendothelial migration
mbez04722
Neurotrophin signaling pathway
mbez04750
Inflammatory mediator regulation of TRP channels
mbez04919
Thyroid hormone signaling pathway
mbez04933
AGE-RAGE signaling pathway in diabetic complications
mbez04935
Growth hormone synthesis, secretion and action
mbez05167
Kaposi sarcoma-associated herpesvirus infection
mbez05169
Epstein-Barr virus infection
mbez05170
Human immunodeficiency virus 1 infection
mbez05171
Coronavirus disease - COVID-19
mbez05200
Pathways in cancer
mbez05205
Proteoglycans in cancer
mbez05206
MicroRNAs in cancer
mbez05214
Glioma
mbez05223
Non-small cell lung cancer
mbez05225
Hepatocellular carcinoma
Module
mbez_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mbez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129547229 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129547229 (PLCG2)
04014 Ras signaling pathway
129547229 (PLCG2)
04370 VEGF signaling pathway
129547229 (PLCG2)
04064 NF-kappa B signaling pathway
129547229 (PLCG2)
04066 HIF-1 signaling pathway
129547229 (PLCG2)
04020 Calcium signaling pathway
129547229 (PLCG2)
04070 Phosphatidylinositol signaling system
129547229 (PLCG2)
04072 Phospholipase D signaling pathway
129547229 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
129547229 (PLCG2)
04613 Neutrophil extracellular trap formation
129547229 (PLCG2)
04625 C-type lectin receptor signaling pathway
129547229 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
129547229 (PLCG2)
04662 B cell receptor signaling pathway
129547229 (PLCG2)
04664 Fc epsilon RI signaling pathway
129547229 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
129547229 (PLCG2)
04670 Leukocyte transendothelial migration
129547229 (PLCG2)
04062 Chemokine signaling pathway
129547229 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
129547229 (PLCG2)
04919 Thyroid hormone signaling pathway
129547229 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
129547229 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
129547229 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
129547229 (PLCG2)
04380 Osteoclast differentiation
129547229 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129547229 (PLCG2)
05206 MicroRNAs in cancer
129547229 (PLCG2)
05205 Proteoglycans in cancer
129547229 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
129547229 (PLCG2)
05214 Glioma
129547229 (PLCG2)
05223 Non-small cell lung cancer
129547229 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
129547229 (PLCG2)
05171 Coronavirus disease - COVID-19
129547229 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
129547229 (PLCG2)
05169 Epstein-Barr virus infection
129547229 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
129547229 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129547229 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mbez04131
]
129547229 (PLCG2)
Enzymes [BR:
mbez01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129547229 (PLCG2)
Membrane trafficking [BR:
mbez04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129547229 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
129547229 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
C2
SH3_1
PH
SH3_9
PH_12
SH3_2
PH_14
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
129547229
NCBI-ProteinID:
XP_055269034
LinkDB
All DBs
Position
Unknown
AA seq
1262 aa
AA seq
DB search
MANVDTLPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEG
FLDIMEIKEIRPGKNSKDFERAKAVRQKEECCFTILYGTQFVLSTLSLAADSKEDAAKWL
SGLKILHQEVMRASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSAKFL
KDKFLEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFLLGNTDRPDASAVHL
HDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWD
EKHDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDG
PDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFATSSFPVVLSIEEHCCVEQQRHMARVFKE
VFGDLLLTKPKEASADQLPSPSQLRGKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGELYM
WDPIDQKWTRHYCAIADAKLSFSDDIEQTVEEELPLDIPPTELHFGEKWFHKKVEKRTSA
EKLLQEYCAETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGAMKYYLTD
NLMFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDMLMRV
PRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKH
ALYRKMKLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYRAK
QSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISPMEGEEADKQIIEDN
PLGSLCRGILNLNIYNVVKAPHGKNQKPFVFILEPKKQGDPPVEFATDSVEELFEWFQSI
REITWKMDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVETKA
DSIVRQKPSDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQM
NHALFSLNGRTGYVLQPESMRAEKYDPMPPESQRKILMTLTVKVLGARHLPKPGRSIACP
FVEVEICGAEYDNNKFKTTVVNDNGLSPVWTPTQEKVTFEIYDPNLAFLRFVVYEEDMFS
DPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQL
RRRQEELNNQLFLYDTHQNLRSANRDALVREFNVNENQLQLYQEKCNRRLREKRVSNSKF
YS
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
atggccaacgtggacaccctcccagagtacgagaagagtcagatcaagcgggccctggag
ctgggcaccgtcatgaccgtgttcagcttccgcaagtccaccccggagcggaggaccgtc
caggtgatcatggagacgcggcaggtggcctggagcaagacggccgacaagatcgagggc
ttcctggacatcatggagataaaggagatccggccagggaagaactccaaggatttcgag
cgcgcgaaagcggtccgccagaaggaagagtgctgcttcaccatcctgtatggcacccag
tttgtcctcagcacgctcagcctggcagccgactcaaaggaagatgcagctaagtggctg
tctggcttgaagatcttacaccaggaagtgatgcgcgcgtccacccccaccatcatcgag
agctggctgagaaagcagatttattctgtggatcaaaccaggagaaacagcatcagcctc
cgggagttgaagaccatcttgcctctggtcaacttcaaagtgagcagtgctaagttcctc
aaagataagttcctggaaataggcgcacataaagatgaactcagctttgaacagttccat
ctcttctataaaaaacttatgtttgaacagcaaaaatcgatccttgacgaattcaaaaag
gattcttccgtgttcctcttgggcaacaccgaccggccggacgcctctgctgtccacctg
catgacttccagcggtttctcttgcatgaacagcaggagctttgggctcaggatctgaac
aaagtccgtgagcggatgacgaagtttattgacgacaccatgagggaaactgctgaaccc
ttcttgtttgtggatgagttcctcacgtacctgttttcccgggagaacagcatctgggac
gagaagcatgacgtggtggacatgcaggacatgaacaaccccttgtctcattactggatc
tcctcgtctcacaacacgtacctcacgggggaccagctgcggagcgagtcgtccccggag
gcctacatccgctgcctgcggatgggctgccgctgcattgagctggactgctgggacggg
cccgacggtaagcccatcatctaccatggctggacgcggaccaccaagatcaagttcgac
gacgtggtgcaggccatcaaggaccacgcctttgccacctccagcttccccgtggtcctg
tccatcgaggagcattgctgtgtggaacagcagcgccacatggccagggtgttcaaggag
gtgttcggggacctgctgctgaccaaacccaaggaggccagcgccgaccagctgccgtcg
cccagccagctgcgcgggaagatcatcatcaagcataagaagctgggcccccgaggtgac
gtggacgtcaacatggaggacaagaaggatgagcacaagcagcagggtgaactgtacatg
tgggaccccatcgaccagaaatggactcgacactactgtgccattgctgatgccaagctg
tccttcagcgatgacattgaacagactgtggaagaggagctgcccctggatatacccccc
acggagctgcattttggggagaagtggttccacaagaaggtggaaaagaggacaagtgct
gagaagctgctgcaggaatactgtgctgagacagggggcaaagatgggaccttcttggtg
cgggagagcgagaccttccccaacgactacaccctgtccttctggcggtcgggccgtgtg
cagcactgccggatccgctccaccatggagggcggggccatgaagtactacctgactgac
aacctcatgttcagcagcatctacgccctcatccagcactaccgcgagacacacctgcgc
tgcgccgagttcgagctccggctgaccgaccccgtgcccaaccccaacccgcacgagtcc
aagccgtggtactacgacgggctgagccgcggagaagcggaggatatgctgatgagggtc
ccccgggacggggccttcctcatccgaaagcgggaaggcaccgactcctacgccatcacc
ttcagggccaggggcaaggtgaagcactgtcgcatcaaccgagacggccggcacttcgtg
ctgggcacctccgcctacttcgagagcctcgtggagctggtcagctactacgagaagcac
gcgctctaccggaagatgaagctgcgctaccccgtgacccccgagctcctggagcgctac
aacatggaaagagatataaactccctctatgatgtcagcaggatgtatgtggatcccagt
gaaatcaatccttcaatgcctcagagaaccgtgaaagctctgtatgactacagagccaag
cagagcgacgagctgagcttttgccgcggtgccctcatccacaacgtctccaaggagcct
gggggctggtggaaaggagactatggaaccagaatccagcagtacttcccgtccaattac
gttgaggacatttcaccaatggaaggggaggaggcggataagcagattattgaagacaat
cccttagggtccctttgcagaggaatcctgaatctcaacatctataatgttgtaaaagcc
ccacacgggaagaaccagaagcctttcgtctttatcttggagcccaagaagcagggcgac
cctccggtagagtttgccacggacagcgtggaggagctgtttgagtggttccagagcatc
cgggagatcacctggaagatggacaccaaggagaacaacatgaagtactgggagaagaac
cagtccatcgccatcgagctctcggacctggtcgtctactgcaagcccaccagcaagacc
aaggacaacctcgaaaaccccgacttccgagaaatccgctcctttgtggagacgaaggct
gacagtatcgtcagacagaagcccagcgatctcctgaaatacaatcaaaagggcctgacc
cgtgtgtaccccaaaggacagcgggtagactcgtccaactatgaccccttccgcctctgg
ctgtgcggctcccagatggtggcgctcaatttccagactccagataagtacatgcagatg
aaccacgccctgttctccctcaatgggcggacgggctacgtcctgcagcctgagagcatg
agggcggagaagtacgaccccatgccgcccgagtcccagaggaagatcctgatgaccctg
acggtcaaggttctgggggcccgtcatctccccaaaccaggacgaagcatcgcgtgtccc
tttgtggaggtggagatatgcggagcggagtatgacaacaacaagttcaagacgacagtt
gtgaatgacaatggcctcagccctgtttggaccccaacacaggagaaggtgacgtttgag
atttatgaccccaaccttgcgtttctgcgctttgtggtttatgaggaagatatgttcagc
gatcccaacttcctggcccacgccacgtaccccattaaaggaatcaagtcaggatttaga
tctgttcctctgaagaacggctacagtgaagacattgagctggcatccctcctggttttc
tgtgagatgcggccagtcctggagagcgaagaggagctgtattcctcctgccgccagctg
cggaggcggcaagaagaactgaacaaccagctctttctgtacgacacccaccagaacctg
cgcagcgccaaccgcgatgccctggtcagagaattcaatgtcaacgagaaccagctgcag
ctgtaccaggagaagtgcaaccgcaggttaagagagaagagagtcagcaacagcaagttt
tactcatag
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integrated database retrieval system
