KEGG   Moschus berezovskii (Chinese forest musk deer): 129548814
Entry
129548814         CDS       T09065                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mbez  Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez00562  Inositol phosphate metabolism
mbez01100  Metabolic pathways
mbez04015  Rap1 signaling pathway
mbez04020  Calcium signaling pathway
mbez04022  cGMP-PKG signaling pathway
mbez04062  Chemokine signaling pathway
mbez04070  Phosphatidylinositol signaling system
mbez04071  Sphingolipid signaling pathway
mbez04072  Phospholipase D signaling pathway
mbez04081  Hormone signaling
mbez04082  Neuroactive ligand signaling
mbez04261  Adrenergic signaling in cardiomyocytes
mbez04270  Vascular smooth muscle contraction
mbez04310  Wnt signaling pathway
mbez04371  Apelin signaling pathway
mbez04540  Gap junction
mbez04611  Platelet activation
mbez04613  Neutrophil extracellular trap formation
mbez04621  NOD-like receptor signaling pathway
mbez04713  Circadian entrainment
mbez04720  Long-term potentiation
mbez04723  Retrograde endocannabinoid signaling
mbez04724  Glutamatergic synapse
mbez04725  Cholinergic synapse
mbez04726  Serotonergic synapse
mbez04728  Dopaminergic synapse
mbez04730  Long-term depression
mbez04742  Taste transduction
mbez04750  Inflammatory mediator regulation of TRP channels
mbez04911  Insulin secretion
mbez04912  GnRH signaling pathway
mbez04915  Estrogen signaling pathway
mbez04916  Melanogenesis
mbez04918  Thyroid hormone synthesis
mbez04919  Thyroid hormone signaling pathway
mbez04921  Oxytocin signaling pathway
mbez04922  Glucagon signaling pathway
mbez04924  Renin secretion
mbez04925  Aldosterone synthesis and secretion
mbez04926  Relaxin signaling pathway
mbez04927  Cortisol synthesis and secretion
mbez04928  Parathyroid hormone synthesis, secretion and action
mbez04929  GnRH secretion
mbez04933  AGE-RAGE signaling pathway in diabetic complications
mbez04934  Cushing syndrome
mbez04935  Growth hormone synthesis, secretion and action
mbez04961  Endocrine and other factor-regulated calcium reabsorption
mbez04970  Salivary secretion
mbez04971  Gastric acid secretion
mbez04972  Pancreatic secretion
mbez04973  Carbohydrate digestion and absorption
mbez05010  Alzheimer disease
mbez05016  Huntington disease
mbez05017  Spinocerebellar ataxia
mbez05022  Pathways of neurodegeneration - multiple diseases
mbez05142  Chagas disease
mbez05143  African trypanosomiasis
mbez05146  Amoebiasis
mbez05163  Human cytomegalovirus infection
mbez05200  Pathways in cancer
mbez05415  Diabetic cardiomyopathy
mbez05417  Lipid and atherosclerosis
Module
mbez_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mbez00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    129548814 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    129548814 (PLCB3)
   04310 Wnt signaling pathway
    129548814 (PLCB3)
   04371 Apelin signaling pathway
    129548814 (PLCB3)
   04020 Calcium signaling pathway
    129548814 (PLCB3)
   04070 Phosphatidylinositol signaling system
    129548814 (PLCB3)
   04072 Phospholipase D signaling pathway
    129548814 (PLCB3)
   04071 Sphingolipid signaling pathway
    129548814 (PLCB3)
   04022 cGMP-PKG signaling pathway
    129548814 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    129548814 (PLCB3)
   04081 Hormone signaling
    129548814 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    129548814 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129548814 (PLCB3)
   04613 Neutrophil extracellular trap formation
    129548814 (PLCB3)
   04621 NOD-like receptor signaling pathway
    129548814 (PLCB3)
   04062 Chemokine signaling pathway
    129548814 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    129548814 (PLCB3)
   04922 Glucagon signaling pathway
    129548814 (PLCB3)
   04929 GnRH secretion
    129548814 (PLCB3)
   04912 GnRH signaling pathway
    129548814 (PLCB3)
   04915 Estrogen signaling pathway
    129548814 (PLCB3)
   04921 Oxytocin signaling pathway
    129548814 (PLCB3)
   04926 Relaxin signaling pathway
    129548814 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    129548814 (PLCB3)
   04918 Thyroid hormone synthesis
    129548814 (PLCB3)
   04919 Thyroid hormone signaling pathway
    129548814 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    129548814 (PLCB3)
   04916 Melanogenesis
    129548814 (PLCB3)
   04924 Renin secretion
    129548814 (PLCB3)
   04925 Aldosterone synthesis and secretion
    129548814 (PLCB3)
   04927 Cortisol synthesis and secretion
    129548814 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    129548814 (PLCB3)
   04270 Vascular smooth muscle contraction
    129548814 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    129548814 (PLCB3)
   04971 Gastric acid secretion
    129548814 (PLCB3)
   04972 Pancreatic secretion
    129548814 (PLCB3)
   04973 Carbohydrate digestion and absorption
    129548814 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    129548814 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    129548814 (PLCB3)
   04725 Cholinergic synapse
    129548814 (PLCB3)
   04728 Dopaminergic synapse
    129548814 (PLCB3)
   04726 Serotonergic synapse
    129548814 (PLCB3)
   04720 Long-term potentiation
    129548814 (PLCB3)
   04730 Long-term depression
    129548814 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    129548814 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    129548814 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    129548814 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    129548814 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129548814 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    129548814 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    129548814 (PLCB3)
   05142 Chagas disease
    129548814 (PLCB3)
   05143 African trypanosomiasis
    129548814 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129548814 (PLCB3)
   05016 Huntington disease
    129548814 (PLCB3)
   05017 Spinocerebellar ataxia
    129548814 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    129548814 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129548814 (PLCB3)
   05415 Diabetic cardiomyopathy
    129548814 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    129548814 (PLCB3)
   04934 Cushing syndrome
    129548814 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mbez04131]
    129548814 (PLCB3)
Enzymes [BR:mbez01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     129548814 (PLCB3)
Membrane trafficking [BR:mbez04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    129548814 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    129548814 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 129548814
NCBI-ProteinID: XP_055271611
LinkDB
Position
Unknown
AA seq 1234 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEETSSRNLVTLRVDSNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNKQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVSLPSPQDLMGRILVKNKKRHRLGSGVPDS
SVRKRPLEQSNSALSESSATTDPSSPQLGSPSSDSCPGLSNGEEAGLEKPSLEPQKSLGE
EGLQRGPDALGPGYREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANAVRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP
FDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQAGPETSQETQSQQL
GYQLNPHPTPSPLDASPRRPPGPATSPTSSSISSSISSPGQRDDLIASILSEVAPAPLDE
LRGHKALVKLRSRQERDFRELYKKHQRKAVALTRRLLDNLAQARAGSRCQQRPGVLSGED
ERAEEEEVSRFQEFQKKQVQCLLELRAAQADTEAARRLEHLQQAQLKLREVVLDAHMTQL
KKLKEINEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLE
EAQKQRQERLVAGQQQILQQLTEEEPKLLAQLVQECQQQRERLPQEIRWSLLGETSEGLG
DGHLVACASNGHAPGSSGHLPGADSESQEETTKL
NT seq 3705 nt   +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgttgcagctggagccgcccaccgtcgtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggagacctccagtcggaacctg
gtaaccctgcgtgtggactccaatggcttcttcttgtactggacgggacccaacatggag
gtggacacacttgacatcagttccatcagggacaccaggacaggccgttatgcccgcctg
cccaaggaccctaagatccgggaggtgttgggctttgggggccctgatgcccggttggag
gagaagctgatgacagtggtggctgggccagacccggtgaatacaacgttcttgaacttc
atggcagtgcaggatgatacagccaaggtctggtccgaggagctcttcaagttggctatg
aacatcctggctcagaatgcctcccggaacaccttcttgcgcaaagcatacacgaagttg
aagctgcaggtaaaccaggatggaaggattccagtcaagaacatcctgaagatgttctca
gcagacaagaagcgggtagaaactgcactggaatcctgtggcctcaatttcaaccgaagc
gagtccatccggcctgacgagttttccttggaaatctttgagcggttcctgaacaagctg
tgtctgcggccggacattgacaagatcctgctggagataggtgccaagggcaaaccttac
ctgacgctggagcagctcatggatttcatcaaccagaagcagcgggacccgcggctcaac
gaagtgctgtacccgcctctgcggccctcccaggctcggctgctcatcgagaagtacgag
cccaacaagcagttcctggagcgagaccagatgtccatggagggcttcagccgctacctg
ggaggtgaggagaacggcattctgccgcttgaggccttggatctgagcgcagacatgacc
cagccgctcagcgcctacttcatcaattcctcgcataacacctatctcacggcggggcag
ctggccggaacctcgtccgtggagatgtatcggcaggcgctgttgtggggctgccgctgc
gtggagctggacgtgtggaaggggcggccacccgaggaggagccgttcatcacacacggc
ttcaccatgaccacggaggtgccactgagagacgtgctcgaggccatcgcggagaccgcc
ttcaagacctcgccctaccccgtcatcctctcctttgagaaccatgtggactcggcgaaa
cagcaggccaagatggccgagtactgccgctccatctttggggacgctctgctcatcgac
cccctggacaagtacccgctggccccaggcgtctccctgcccagcccccaggacctgatg
ggccgcatcctggtgaagaacaagaagcggcaccgactcggcagcggcgtccctgacagc
tccgtgcgcaagcggccactggaacagagcaactcggccctgagcgagagctctgccacc
accgacccctcctcgccccagctcgggtcccccagctctgacagctgcccaggcctgagc
aatggggaggaggcaggcctcgagaagcccagcctggagcctcagaagtctctgggggaa
gagggtttgcagcggggccctgatgctcttggacctggctaccgggaggatgaggaagag
gacgaggaggaggaggaacagacggaccccaaaaagccgaccacggacgagggcaccgcc
agcagtgaggtcaacgccactgaggaaatgtccacactcgtcaactacatcgagcctgtc
aagttcaagtccttcgaggctgctcgaaagaggaacaagtgcttcgagatgtcatccttc
gtggagaccaaggccatggagcagctgaccaagagccccatggagtttgtggaatacaac
aagcagcagctcagccgcatctaccccaagggcacccgcgtggactcgtccaactacatg
ccccagctcttctggaacgtgggctgccagctcgttgcactcaacttccagaccctagat
gtgccaatgcagctcaatgccggcgtgttcgagtacaacgggcgcagcggctacctactc
aaacctgagttcatgcggcggccggacaagtcctttgaccccttcaccgaagtcatcgtg
gacggcatcgtggccaatgctgtgcgggtcaaggtgatctcggggcagttcctgtccgac
aggaaggtgggcatctacgtggaggtggacatgttcgggctccccgttgacacgcggcgc
aagtaccgcacgcgaacctcacaggggaattcattcaaccccgtgtgggatgaggagccg
ttcgacttccccaaggtggtgctgcccacgctggcttcgctgcgcatcgcggcctttgag
gaggggggcaagttcgtggggcaccggatcctgcccgtctccgccatccgctcagggtac
cactacatctgcctgcgaaacgaggccaaccagccgctgtgcctgccagccctgctcatc
tacaccgaggcctccgactacatccccgatgaccaccaggactatgcagaggccctgatc
aaccccatcaagcatgtcagcctgatggaccagagggccaagcagctggccgccctcatt
ggggaaagtgaggctcaggctggcccagagacgagccaggagacccagtctcagcagctg
gggtaccaactgaacccacaccccacgcccagcccactggacgcctccccgcgccggccc
ccaggccccgccacctcccccaccagctcctccatcagctcctccatcagcagcccaggt
cagcgtgatgatctcatcgccagcatcctctcagaggtggccccggccccgctggacgag
ctccgaggccacaaggccctggtgaagctccgcagccggcaagagcgagacttccgggag
ctgtacaagaaacatcagcggaaggccgttgccctcacacgccggttgctcgacaacctg
gcccaggcccgcgcggggagcaggtgccaacagcgacctggtgtcttaagcggggaggac
gagagggcagaagaggaagaggttagcaggtttcaagagttccagaagaaacaggtgcag
tgtctgctggagctgagggcggcccaggcggacacagaggcggcgcggaggctggagcac
ctgcagcaggctcagctgaagctcagggaggttgtcctggatgctcacatgactcagctg
aagaaactgaaggagataaacgagagggagaagaaggaactgcagaagatcctggacagg
aaacgccacaacagtatctcagaggccaagaccagggagaaacataagaaggaggcggaa
ctgacagagattaaccgtcggcacatcactgagtcggtcaactccatccgtcggctggag
gaggcccagaagcagcggcaggaacgccttgtggccgggcagcagcagatcctccaacag
ctgacggaagaggagcccaagctgctggctcagctggtccaggagtgtcagcagcagcgg
gagaggctgccccaggagatccgctggagcctgctgggcgagacatcagagggacttggg
gacgggcatctggtcgcctgtgccagcaacggtcacgcgcctgggagcagcgggcacctg
cctggcgctgactcagagagccaggaggagactacaaagctctga

DBGET integrated database retrieval system