KEGG   Moschus berezovskii (Chinese forest musk deer): 129549745
Entry
129549745         CDS       T09065                                 
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
mbez  Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez04022  cGMP-PKG signaling pathway
mbez04024  cAMP signaling pathway
mbez04062  Chemokine signaling pathway
mbez04071  Sphingolipid signaling pathway
mbez04270  Vascular smooth muscle contraction
mbez04350  TGF-beta signaling pathway
mbez04360  Axon guidance
mbez04510  Focal adhesion
mbez04520  Adherens junction
mbez04530  Tight junction
mbez04611  Platelet activation
mbez04670  Leukocyte transendothelial migration
mbez04810  Regulation of actin cytoskeleton
mbez04921  Oxytocin signaling pathway
mbez05135  Yersinia infection
mbez05163  Human cytomegalovirus infection
mbez05200  Pathways in cancer
mbez05205  Proteoglycans in cancer
mbez05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:mbez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    129549745 (ROCK1)
   04071 Sphingolipid signaling pathway
    129549745 (ROCK1)
   04024 cAMP signaling pathway
    129549745 (ROCK1)
   04022 cGMP-PKG signaling pathway
    129549745 (ROCK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129549745 (ROCK1)
   04520 Adherens junction
    129549745 (ROCK1)
   04530 Tight junction
    129549745 (ROCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    129549745 (ROCK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129549745 (ROCK1)
   04670 Leukocyte transendothelial migration
    129549745 (ROCK1)
   04062 Chemokine signaling pathway
    129549745 (ROCK1)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    129549745 (ROCK1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    129549745 (ROCK1)
  09158 Development and regeneration
   04360 Axon guidance
    129549745 (ROCK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129549745 (ROCK1)
   05206 MicroRNAs in cancer
    129549745 (ROCK1)
   05205 Proteoglycans in cancer
    129549745 (ROCK1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    129549745 (ROCK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    129549745 (ROCK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mbez01001]
    129549745 (ROCK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mbez03036]
    129549745 (ROCK1)
Enzymes [BR:mbez01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     129549745 (ROCK1)
Protein kinases [BR:mbez01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   129549745 (ROCK1)
Chromosome and associated proteins [BR:mbez03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    129549745 (ROCK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Cortex-I_coil Pkinase_C APH
Other DBs
NCBI-GeneID: 129549745
NCBI-ProteinID: XP_055273096
LinkDB
Position
Unknown
AA seq 1355 aa
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRSLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSITQLESLNRELQERNRILENSKSQMD
KDYYQLQAVLEAERRDRGHDSEKIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLIENKDRMEDEVKNLTLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTLSRLEETNSMLTKDIELLRKENE
ELTDKMRKAEEEYKLKKEEEINILKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNEMQAQLVEECAHKNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDLEVEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHIDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKASS
NT seq 4068 nt   +upstreamnt  +downstreamnt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcagattgtctgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataagtccaccaggaag
gtatacgctatgaagctcctcagcaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaacagtccttgggttgttcagctgttt
tatgcattccaagatgatcgttatctctatatggtaatggaatacatgcctggtggagat
cttgtaaatttaatgagcaactatgatgtgcctgaaaaatgggcccgattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggttttatccatagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttggcagattttggtacttgt
atgaagatgaataaggaaggaatggtacgatgtgatacagcagttggaacacctgattat
atttcccctgaagtattaaaatctcaaggtggcgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacaccattttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattctcttaccttccct
gatgataatgacatatcaaaagaagcaaaaaatctgatttgtgccttccttactgacaga
gaggtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcagtgggcttgggaaacacttcgagacactgtagcaccagtcgtacctgatttaagt
agtgacatagacacaagtaactttgatgacttggaagaagataaaggagatgaagaaaca
ttccctatacctaaagcttttgttggcaatcaactaccttttgtaggatttacatattat
agcaatcgtagatacttatcttcagcaaatcctaacgataacagaactagctctaatgtg
gataaaagcttgcaggaaaatttgcagaaaacaatttataagctggaagaacagttacat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacgtcaaacataaaacta
gacaagataatgaaagagttggacgaagagggcaatcaaagaagaagtctagaatctaca
gtatctcagattgagaaggagaaaatgttgctacagcacagaattaatgaataccaaaga
aaagcagaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtcagccagaattcacagcttgctaatgagaagcta
gcacaattacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gcggttagattaaggaagagtcacacagagatgagcaaatccatcactcagctagagtcc
ctaaacagagaactgcaggagagaaatagaattttagagaattccaagtcacaaatggac
aaagattattaccaactgcaggctgtattagaagctgaacgaagagacagaggtcatgat
tctgagaagattggagacttacaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaggctcaagacatgcttaat
cattcagaaaaggaaaagaataacttagaaatagatttaaactacaagcttaaatcgtta
cagcaacggttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgagatggaaaaaaagctg
aaggaggagagagaagctcgagagaaggctgaaaatagggttgttcagattgagaagcag
tgttctatgctagatgttgatctgaaacaatctcagcagaagctggagcatttgattgaa
aataaagacaggatggaggatgaagttaagaatctaaccctgcagctggagcaggaatca
aataagcgactgttgttacaaaatgaattgaagactcaagcatttgaggcagacaattta
aaaggtttagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgaattagctcagcttacaaaacagtacagagggaatgaagggcagatgcgg
gagctgcaggatcagctggaagcggagcagtatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaaaacttaaagaaaatacaggaa
ctacaaagtgaaaaagaaactcttgctactcagttggatctagcagaaacaaaggctgaa
tctgagcagctggctcgagggcttctggaagagcagtattttgaactgacccaagaaagc
aagaaagctgcttcaagaaatagacaagagattacagacaaagatcacactcttagtcgg
cttgaagaaacaaacagcatgctaaccaaagatattgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggaaggcagaggaagaatataaattgaagaaggaggaggag
atcaatatccttaaggctgcctttgaaaagaatatcaatacagaacgaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcgaaaggactttaaaatcgatagaaag
aaagccaatacgcaggatttgagaaagaaagaaaaagaaaatcgaaagctccaacttgaa
ctcaaccaggaaagagagaaattcaaccaaatggtagtgaaacatcagaaggagctgaat
gaaatgcaagcgcaattggtagaagaatgtgcacataagaatgagcttcagatgcagttg
gccagcaaagagagtgacattgagcagctgcgtgccaaacttctggacctttcagattct
acaagtgttgctagttttcccagtgctgatgaaactgatggaaaccttccagaatcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaaagatacggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccgtctatggtattggacattgataaattgtttcatgttcgtcctgtaaca
caaggagatgtgtacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggcgaatgtagaaaagacttagaggtggaaccagtacaacaggctgaaaaa
acaaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcccgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctggag
tgtcgacgatgccatgttaagtgccacagagaccacatagataagaaagaggacttgatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctactagcgtgt
tctcaggatgaacaaaaaaaatgggtaactcatttagtaaagaagatccctaagaatcca
ccatctggttttgtgcgtgcatcccctcgaacactttctacaaggtccactgcaaatcag
tctttccggaaagttgtcaaaaatacatctggaaaagctagcagttaa

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