KEGG   Moschus berezovskii (Chinese forest musk deer): 129552423
Entry
129552423         CDS       T09065                                 
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor isoform X1
  KO
K05099  proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Organism
mbez  Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez01521  EGFR tyrosine kinase inhibitor resistance
mbez04010  MAPK signaling pathway
mbez04014  Ras signaling pathway
mbez04015  Rap1 signaling pathway
mbez04020  Calcium signaling pathway
mbez04151  PI3K-Akt signaling pathway
mbez04360  Axon guidance
mbez04510  Focal adhesion
mbez04520  Adherens junction
mbez05100  Bacterial invasion of epithelial cells
mbez05144  Malaria
mbez05200  Pathways in cancer
mbez05202  Transcriptional misregulation in cancer
mbez05205  Proteoglycans in cancer
mbez05206  MicroRNAs in cancer
mbez05208  Chemical carcinogenesis - reactive oxygen species
mbez05211  Renal cell carcinoma
mbez05218  Melanoma
mbez05223  Non-small cell lung cancer
mbez05225  Hepatocellular carcinoma
mbez05226  Gastric cancer
mbez05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mbez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129552423 (MET)
   04014 Ras signaling pathway
    129552423 (MET)
   04015 Rap1 signaling pathway
    129552423 (MET)
   04020 Calcium signaling pathway
    129552423 (MET)
   04151 PI3K-Akt signaling pathway
    129552423 (MET)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129552423 (MET)
   04520 Adherens junction
    129552423 (MET)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    129552423 (MET)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129552423 (MET)
   05202 Transcriptional misregulation in cancer
    129552423 (MET)
   05206 MicroRNAs in cancer
    129552423 (MET)
   05205 Proteoglycans in cancer
    129552423 (MET)
   05208 Chemical carcinogenesis - reactive oxygen species
    129552423 (MET)
   05230 Central carbon metabolism in cancer
    129552423 (MET)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    129552423 (MET)
   05226 Gastric cancer
    129552423 (MET)
   05218 Melanoma
    129552423 (MET)
   05211 Renal cell carcinoma
    129552423 (MET)
   05223 Non-small cell lung cancer
    129552423 (MET)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    129552423 (MET)
  09174 Infectious disease: parasitic
   05144 Malaria
    129552423 (MET)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    129552423 (MET)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mbez01001]
    129552423 (MET)
Enzymes [BR:mbez01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     129552423 (MET)
Protein kinases [BR:mbez01001]
 Receptor tyrosine kinases (RTK)
  MET family
   129552423 (MET)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr TIG Pkinase Sema PSI Kinase-like Pkinase_fungal Linker_histone
Other DBs
NCBI-GeneID: 129552423
NCBI-ProteinID: XP_055276793
LinkDB
Position
Unknown
AA seq 1384 aa
MKAPAVLAPGILVLLFTFVQKSDGECKDALVKSRMNVNMQYQLPNFTAETSIQNVVLHKH
HIYLGAINYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMAL
LVDTYYDDQLISCGSVHRGTCQRHVLPPNNTADIESEVHCMYSPQADEETSQCPDCVVSA
LGTKVLLSEKDRFINFFVGNTINSSYIPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
ELRDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSADSGLHSYMEMPLECI
LTEKRRKRSTKQEVFNILQAAYVSKPGAQLARQIGANLNDDILYGVFAQSKPDSSEPMNR
SAVCAFPVKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRNDEYRTE
FTTALPRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSLTPHVNF
RLDSHPVSPEVIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPSFVQCG
WCHDKCVRLEECPSGTWTQETCLPTIYKVFPTSAPLEGGTTLTVCGWDFGFKRNNKFDLK
KTRVLLGNESCTLTLSESTTNMLKCTVGPVMNEHFNMSIVISNSRGSVQYSTFSYVDPII
TSISPNYGPKTGGTLLTLTGKHLNSGNSRHISIGGKTCTLKSVSHSILECYTPAQSAPTE
FSVKLKIDLANREMNSFIYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSILRMVINV
HEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVVISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSHSEAVLCTVPND
LLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWLKKRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVSGED
DDDT
NT seq 4155 nt   +upstreamnt  +downstreamnt
atgaaggcccctgctgtgcttgcacctggcattcttgtgcttctgtttaccttcgtgcag
aagagcgatggggagtgtaaagatgcactagtaaagtccaggatgaatgtgaacatgcag
tatcagcttcctaacttcactgcagaaacatccattcagaatgttgttttgcacaaacat
cacatttacctcggtgctattaactacatttacgttttaaatgacaaagaccttcagaag
gttgctgagtacaagactgggcctgtgctggaacacccagattgtttcccatgtcaggac
tgcagccacaaagccaatttatcaggtggtgtttggaaagataacatcaacatggctctg
cttgttgacacgtactatgatgatcaactcattagctgtggcagtgtccacagagggacc
tgccagcgacatgtccttccacccaacaatactgcggacatagagtcagaggttcactgc
atgtactctcctcaggcagacgaagagaccagccagtgtcctgactgtgtggtgagtgcc
ctgggaaccaaagtcctactgtctgaaaaggatcgattcatcaacttcttcgtgggcaat
accataaattcttcttacattccagatcattcattgcactcgatatcggtgagaaggcta
aaggaaacgcaagatggttttaagtttttgacagaccaatcctatattgatgttctacct
gagctccgagattcctaccccattaagtatgtccacgcctttgaaagcaaccattttatt
tactttttgacagtccaacgggaaactctagatgctcagacttttcacacaagaataatc
aggttctgttccgcagactctggattgcattcgtacatggaaatgcctctggagtgtatt
ctgacggaaaagagaagaaagagatccacaaagcaggaagtgtttaatattctccaagct
gcatatgtcagtaagcctggggctcagctcgctaggcaaataggtgccaacctgaatgat
gacattctgtacggggtgtttgcacaaagcaagccagattcctcagaaccaatgaatcgc
tctgctgtctgtgcattccctgtcaaatatgtcaatgagttcttcaacaagatcgtcaac
aaaaacaatgtgagatgtctccagcacttttatggccccaaccatgaacactgcttcaac
aggacacttttgagaaattcatcaggatgtgaagttcgcaatgatgaatatcgaacagag
tttaccacagctttgccgcgtgttgacttattcatgggccagttcaaccaagtcctctta
acatctatatccacctttatcaaaggagatctcaccatcgccaatctcgggacgtcagag
ggtcgattcatgcaggttgtagtttctcgatcaggatcattaactcctcacgtgaatttt
cgcctggattcccaccctgtgtctccagaagtgattgtggagcaccctctaaaccagaat
ggctatacactggttgtcactgggaagaagatcaccaagatcccgctgaatggcctgggc
tgtgaacatttccagtcctgcagtcagtgcctctccgccccttcctttgtgcaatgtggc
tggtgccatgataaatgtgtgcgattggaggaatgccccagtggaacgtggactcaagag
acctgtctgccaacaatctacaaggtttttccaactagtgccccccttgaaggagggaca
acactgactgtttgtggctgggactttggattcaagaggaataataaatttgacttgaag
aaaaccagagttctccttggaaatgagagttgcaccttaaccttaagtgagagcacaact
aacatgttgaaatgcacagttggtcctgtaatgaatgaacatttcaatatgtccatagtt
atttcaaacagtcgtgggtcagtacagtatagtacattttcctatgtggatcctataata
acaagtatttctccaaattatggtccaaaaactggtggcactttacttacattaactgga
aagcacctaaacagtggaaattcaagacacatttcaattggtggaaaaacatgtacttta
aaaagtgtttcacatagtattctcgaatgttataccccagcccaaagcgcaccaactgag
ttttctgttaaattgaaaattgacttagccaaccgagagatgaacagcttcatttaccgg
gaagaccccattgtctatgaaatacatcccaccaaatcttttattagtggtgggagtaca
ataacaggtgttggaaaaaacctgaattcagttagtatcctaaggatggtgataaatgtg
catgaagccggaaggaactttacagtggcatgtcaacatcgctctaattcagagataatc
tgctgtacaactccttcactacaacagctgaacctacaactccccctgaaaaccaaagcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtggtgatctcaataggcaatgaaaatgtactggaa
attaagggaaatgatattgaccctgaagcagttaaaggggaagtgttaaaagttggaaat
aagagctgtgaaaatatacactcacattctgaagctgttttatgtacggtccccaatgac
ctactgaaattgaacagcgaactaaatatagagtggaagcaagcaatttcttcaactgtt
cttggaaaagtgatagttcaaccagatcagaatttcacaggattgattgttggtgttgtc
tcaatatcaataatactcttactgttacttgggcttttcctgtggctgaaaaaaaggaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactccacat
ttggataggcttgtcagtgcccgaagtgtaagcccaactacagaaatggtttccaatgaa
tctgtagactaccgagctacttttccagaagaccagtttcctaattcatctcagaatggg
tcatgcagacaagtgcagtatcctctgacagatctatcccccatcttaactagtggggac
tctgatatatccagtccattactgcaaaataccgtccacatcgacctcagtgctctaaat
ccagagctggtccaggcagttcagcacgtagtcattgggccaagcagtctgattgtacat
ttcaatgaagtcataggaagaggacattttgggtgtgtatatcatggaactttgttggac
aacgatgataagaaaattcactgtgctgtgaaatccttgaatagaatcactgacatagga
gaagtttcccaatttctgactgagggaatcatcatgaaagattttagtcatcccaatgtt
ctctcgcttttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccatac
atgaaacacggggatcttcgaaatttcattagaaatgagactcataacccgactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggcatggaatatcttgcaagcaaaaag
tttgtccacagagacttggctgcaagaaactgtatgctggatgaaaaattcaccgtcaag
gttgctgattttggtcttgccagagacgtgtatgataaggaatactatagtgtacacaac
aaaacaggtgcaaaactgccagtgaaatggatggccttagaaagcctgcagactcagaaa
tttaccaccaagtcagatgtgtggtcctttggcgtgctcctctgggaactgatgacaaga
ggagcaccaccttatcctgacgtcaacacttttgacataacagtttatttgttgcaagga
agaaggctcctacaacctgaatactgcccagatcccttgtatgaagtgatgctgaaatgc
tggcaccctaaagctgagctgcgcccttccttttctgaactggtctccaggatatccgcg
atattctctactttcattggggagcactatgtccatgtgaatgctacttacgtgaacgtc
aaatgtgtcgctccgtatccttctctgttgtcatcacaagataatgtcagtggcgaggat
gatgatgacacatga

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