Moschus berezovskii (Chinese forest musk deer): 129552531
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Entry
129552531 CDS
T09065
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mbez
Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez00230
Purine metabolism
mbez00670
One carbon pool by folate
mbez01100
Metabolic pathways
mbez01523
Antifolate resistance
Module
mbez_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mbez00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
129552531 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
129552531 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
129552531 (GART)
Enzymes [BR:
mbez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
129552531 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
129552531 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
129552531 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
RimK
Motif
Other DBs
NCBI-GeneID:
129552531
NCBI-ProteinID:
XP_055276995
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSTHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFIVVGPEAPLAAGIVGNLNSVGVRCFGPTAEAAQLESSKRFAKEFMDRHGIA
TARWRAFNKPEEACDFIMSADFPALVVKASGLAAGKGVIVAKSKEEACEAVREIMQGKAF
GEAGETVVVEELLEGEEVSCLCFTDGWTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQEEGMPYTGVLYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNCAAVTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQGGTALKDGKVVTDGGRVLTVTAIRENLISALEEARKGLAAIKFEGAVYRKD
IGFRAIAFLQQPRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFTDPLLACGTDGVGTKLKVAQQCSRHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLRTTEAVIAGIAQACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAVAHITGGGLLENIPRVLPQKLGVNLDAQTWRVPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSEDLVKQTLQDIEQHQEEAWVIGRVVACPEGSPRVKVEH
LIETMQINGSVLESGTLRNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSLAHIVIV
ISNKAAVAGLDKAEKAGIPTRIINHKLYKNRAAFDTAVDEVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGAVRLGENGRICWVTED
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtcattggcaatggaggacgggaacacacactggcctggaaa
cttgcacagtctactcatgtcaaacaagtgttggttaccccaggaaatgcaggcactgcc
tgctctgagaagatttcaaataccgacatctcaatcagtgatcacactgcccttgcacag
ttctgcaaagatgagaaaattgaattcatagttgttggaccagaggcacctctagccgct
ggaattgttgggaacctgaactctgtgggagttcggtgctttggccccacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatcgca
actgcaagatggagagctttcaataaacctgaagaagcctgtgacttcattatgagtgca
gacttcccagctttggttgtgaaggccagtggtcttgcagctgggaaaggagtaattgtt
gccaagagcaaagaggaggcctgtgaagctgtcagggagattatgcagggtaaagctttc
ggagaagcgggagaaacagttgtcgttgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggatggactgtggcccccatgcccccagcccaggaccataagcga
ttgctggagggcgatcagggccccaacacagggggaatgggagcgtactgtccagcccct
caggtttctaaggatttattgctaaaaattaaaaataccattcttcagaggacagtggat
ggcatgcaggaggagggtatgccgtacacaggtgtcctctatgctggtataatgctgacc
aagaacggccccaaagttctggaatttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctacgttagatggcttg
ctctgtacatctctgcctgtttggctggacaactgtgctgccgtaactgtggtcatggca
agtaaaggttatccaggagactacaccaagggtgtagagataacagggtttcctgaggct
caggctttaggactggaggtgttccaaggtggcactgccctaaaagatggcaaggtggtg
actgacgggggtagggtccttactgtcacggccatcagggaaaatctcatctcagccctt
gaagaagccaggaaaggacttgccgctataaagtttgagggagctgtttataggaaagac
atcggctttcgagccatagctttcctccagcagcccaggggcctaacttacaaggaatct
ggggtagacattgcagctggtaatatgctggtccagaaaattaaacctttagcaaaggcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcactgatcctcttctggcctgtggaacagatggcgttgggacgaaactg
aaggttgcccagcagtgcagtagacatgacaccattggtcaggatttggttgcaatgtgt
gtaaatgacattctggcacaaggagcagagcccctctttttcctcgattacttttcctgt
ggaaaacttgacctccgtacgactgaagcggttatcgctgggatcgcccaagcttgtaga
aaggctggatgtgctctcctcggaggtgaaacagcagagatgcctgacatgtaccctcct
ggagagtatgatctagctggttttgccgttggcgccatggagcgggatcagaaacttccc
cacctggaaagaatcacggaaggggacgctgttattggaatcgcttcatctggtcttcac
agcaacggatttagcctcgtgaggaaaattgtagcaaaatcttccctccagtactcttct
ccagcacctgatggctgtggtgaccagaccttaggtgacttacttctaaccccaaccaga
atctacagccactcactgttacctgtcctgcgttcaggacatgttaaggccgttgcgcat
attactggtggaggattactggaaaacatccccagagtcctccctcagaaattgggggtg
aatttagatgcccaaacctggagggtccccaggatcttctcatggttacagcaggaaggc
cacctctctgaagaggagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcggaggacctggtgaagcagactctgcaggatattgagcagcaccaggaagaagcc
tgggtgatcggcagggtggtcgcatgtcccgaaggttctcctcgtgtgaaagtcgagcat
ctgattgaaaccatgcaaataaatggatcagtattggagagtggaaccctgagaaatcat
ttctctgttcaaccgaaaaaggcaagagtagctgtcttaatttctgggacaggatcgaac
ctccaagctctcatagacagcactagggagccaagtagcttggcacacattgtcattgtg
atctccaacaaagctgcagtggctggcttagataaagcagaaaaagccggaattcccacc
agaataattaatcataaattatataaaaatcgtgcagcatttgacactgcagttgacgaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttgtct
ggccccttcgtcagaaaatggaatgggaaaatgctcaatatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggatgctggggtcacagtcaccggg
tgcaccgtgcactttgtagctgaagatgtagatgccggtcaaattatcttacaggaagct
gttccagtgaagaggggtgacactgttgaaactctatctgagagagtaaaattggcagaa
cataaaatatttccctcagccctccagctggtggccagtggagctgtacggcttggagaa
aatggcagaatctgttgggtcacagaggactga
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