KEGG   Moschus berezovskii (Chinese forest musk deer): 129552779
Entry
129552779         CDS       T09065                                 
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial
  KO
K13242  nitric-oxide synthase, endothelial [EC:1.14.13.39]
Organism
mbez  Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez00220  Arginine biosynthesis
mbez00330  Arginine and proline metabolism
mbez01100  Metabolic pathways
mbez04020  Calcium signaling pathway
mbez04022  cGMP-PKG signaling pathway
mbez04066  HIF-1 signaling pathway
mbez04071  Sphingolipid signaling pathway
mbez04151  PI3K-Akt signaling pathway
mbez04370  VEGF signaling pathway
mbez04371  Apelin signaling pathway
mbez04611  Platelet activation
mbez04915  Estrogen signaling pathway
mbez04921  Oxytocin signaling pathway
mbez04926  Relaxin signaling pathway
mbez04931  Insulin resistance
mbez04933  AGE-RAGE signaling pathway in diabetic complications
mbez05415  Diabetic cardiomyopathy
mbez05417  Lipid and atherosclerosis
mbez05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mbez00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    129552779 (NOS3)
   00330 Arginine and proline metabolism
    129552779 (NOS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    129552779 (NOS3)
   04371 Apelin signaling pathway
    129552779 (NOS3)
   04066 HIF-1 signaling pathway
    129552779 (NOS3)
   04020 Calcium signaling pathway
    129552779 (NOS3)
   04071 Sphingolipid signaling pathway
    129552779 (NOS3)
   04022 cGMP-PKG signaling pathway
    129552779 (NOS3)
   04151 PI3K-Akt signaling pathway
    129552779 (NOS3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129552779 (NOS3)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    129552779 (NOS3)
   04921 Oxytocin signaling pathway
    129552779 (NOS3)
   04926 Relaxin signaling pathway
    129552779 (NOS3)
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129552779 (NOS3)
   05418 Fluid shear stress and atherosclerosis
    129552779 (NOS3)
   05415 Diabetic cardiomyopathy
    129552779 (NOS3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    129552779 (NOS3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    129552779 (NOS3)
Enzymes [BR:mbez01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     129552779 (NOS3)
SSDB
Motif
Pfam: NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1
Other DBs
NCBI-GeneID: 129552779
NCBI-ProteinID: XP_055277515
LinkDB
Position
Unknown
AA seq 1205 aa
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSRAPTPATPHAPDHSPAPSSPT
LTRPPEGPRFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKLQTRPSQGPP
PAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDE
APELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYM
STEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIV
DHHAATVSFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPD
PWKGSAAKGTGITRKKTFKEVANAVKISASLMGTLMAKRVKATILYASETGRAQSYAQQL
GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAKAAFQASCETFCVGEEAKA
AAQDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQAAVLSVENLQSSKSTRAT
ILVRLDTAGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPTESVAVEQLEKGSPG
GPPPSWVRDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEEPSEQQELETLSQDPR
RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEVHLTVA
VLAYRTQDGLGPLHYGVCSTWLSQLKIGDPVPCFIRGAPSFRLPPDPYVPCILVGPGTGI
APFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFS
REPDSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDME
LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGP
DTPGP
NT seq 3618 nt   +upstreamnt  +downstreamnt
atgggcaacttgaagagcgtgggccaggagcccggacccccctgcggcctggggctaggg
ctgggcctcgggctgtgtggcaagcagggcccggcctccccagcacctgagcccagccgg
gcccccacacccgccaccccgcacgcaccggaccacagcccagctcccagcagccccacg
ctgacccggcctccggaggggcccaggttccctcgtgtgaagaactgggagctggggagc
atcacctacgacaccctgtgcgcgcagtcccagcaggacgggccctgcacccccagacgc
tgcttgggctccctggtgttgccccggaaactgcagacccggccctcccagggacctcca
cccgctgagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatc
aagaggagcggctcccaggctcacgaggagcggcttcaggaggtggaggccgaggtggca
tccacaggcacctaccacctccgggagagcgagctggtgttcggggccaagcaggcctgg
cgcaacgcaccccgctgtgtgggccgcatccagtgggggaagctgcaggtgttcgatgcc
cgggactgcagctcagcacaggagatgttcacctacatctgcaaccacatcaagtatgcc
accaaccgtggcaaccttcgctcggccatcacagtgttcccgcagcgcgccccaggccgc
ggagacttccggatctggaacagccagctggtgcgctatgcgggctatagacagcaggac
ggctccgtgcgcggggacccggccaacgtggagatcacggagctctgcatccagcacggc
tggacccccggaaacggccgcttcgacgtgctgcccctgctgctccaggccccagatgag
gctccggagctctttgttctgccccccgagctggtcctcgaagtgcccctggagcacccc
acactggagtggttcgcggccctgggcctgcgctggtatgccctcccggccgtgtccaac
atgctgctggaaatcgggggtctggagttccccgcggcccccttcagcggctggtacatg
agcacagagatcggcacgcggaacctgtgtgaccctcaccgctacaacatcctggaggat
gtggctgtctgcatggacctcgacacccggaccacctcgtccctgtggaaggacaaggcg
gccgtggagatcaacctggctgtgctgcacagctatcagctcgccaaggtgaccatcgtg
gaccaccacgccgccacggtgtccttcatgaagcacctggagaacgagcagaaggccagg
gggggctgccccgccgactgggcctggattgtgccccccatctcgggcagcctgacgccc
gtcttccaccaggagatggtcaactacgtcctgtcccctgccttccgctaccagccagac
ccctggaaggggagcgcggccaagggcaccggcatcaccaggaagaagacctttaaggaa
gtggccaacgcggtgaagatctctgcctcgctcatgggcaccctgatggccaagcgagtg
aaggcgaccatcctgtatgcctccgagaccggccgggcccagagctacgctcagcagctg
gggaggctcttccggaaggccttcgacccccgggtcctctgcatggatgagtatgacgtg
gtgtccctggagcacgagacgctggtgctggtggtgaccagcacctttgggaatggcgat
cccccggagaatggagagagttttgcagctgccctgatggagatgtcggggccctacaac
agctccccgaggccagaacagcacaagagctacaagatccgcttcaacagcgtctcctgc
tcagacccgctggtgtcctcctggcggcggaagagaaaggagtccagcaacacggacagc
gcaggggcactggggaccctgaggttctgtgtgttcggactgggctcccgggcgtacccc
cacttctgcgccttcgcgcgagcggtggacacccggctggaagagctgggaggggagcgg
ctgctgcagctgggccagggcgacgagctctgcggccaggaggaggccttccgtggttgg
gcaaaggcggccttccaggcctcctgcgagacattctgcgtcggggaggaggccaaggcc
gccgcccaggacatcttcagccccaaacggagctggaaacgccagaggtaccggctgagc
acccaggctgagggcctccagctgctgccaggcctgatccacgtgcacagacggaagatg
tttcaggccgcagtcctctcagtggaaaacctgcagagcagcaagtccacgcgggccacc
atcctggtgcgcctggacactgcaggccaggaggggctgcagtaccagccgggggaccac
ataggcatctgcccgcccaaccggccgggccttgtggaggcgctgctgagccgcgtggag
gacccgccgccacccaccgagtctgtggctgtggagcagctggagaagggcagcccaggc
ggccctcctcccagctgggtgcgggacccgcggctgcccccgtgcacgctgcgccaggct
ctcaccttcttcctggacatcacctccccgcccagcccccggcttctccgactgctcagc
accctggctgaagaacccagcgagcagcaggagctcgagaccctcagtcaggacccccgg
cgctacgaggagtggaagtggttccgctgccctacgctgctggaggtgctggagcagttc
ccatccgtggcactgcccgccccactgctcctcacccagctgcccctgctgcagccccgg
tactactccgtcagctcggcccccagcgcccaccccggagaggtccacctcactgtggcc
gtgctggcatacaggacccaagatgggctgggtcccctacactacggggtctgctccacg
tggctgagccagctcaagattggagaccctgtgccctgcttcatcaggggagctccctcc
ttccggctgccgcctgacccctacgtgccctgcatcctcgtgggccccggcaccggcatc
gcccctttccggggattctggcaggagcggctgcatgacattgagagcaaagggctgcag
cccgcccccatgaccctggtgttcggctgccggtgctcccaactcgaccatctctaccgc
gacgaggtgcaggacgcccagcagcgcggggtgtttggccgcgtcctcaccgccttctcc
agggaacctgacagccccaagacctacgtacaggacatcctgaggaccgagctggctgcc
gaggtgcaccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgacgtcact
atggcaaccagcgtcctgcagacggtgcagcgcatcttggcgacagagggcgacatggaa
ctagacgaggccggcgacgtcattggcgtgctgcgggatcagcaacgctatcacgaggat
attttcggcctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttc
tccctgcaggagcggcatctgcggggcgcggtgccctgggccttcgaccctcccggccca
gacacccccggcccctga

DBGET integrated database retrieval system