KEGG   Moschus berezovskii (Chinese forest musk deer): 129555633
Entry
129555633         CDS       T09065                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mbez  Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez01522  Endocrine resistance
mbez04010  MAPK signaling pathway
mbez04012  ErbB signaling pathway
mbez04014  Ras signaling pathway
mbez04024  cAMP signaling pathway
mbez04068  FoxO signaling pathway
mbez04071  Sphingolipid signaling pathway
mbez04137  Mitophagy - animal
mbez04140  Autophagy - animal
mbez04141  Protein processing in endoplasmic reticulum
mbez04210  Apoptosis
mbez04215  Apoptosis - multiple species
mbez04217  Necroptosis
mbez04310  Wnt signaling pathway
mbez04380  Osteoclast differentiation
mbez04510  Focal adhesion
mbez04530  Tight junction
mbez04620  Toll-like receptor signaling pathway
mbez04621  NOD-like receptor signaling pathway
mbez04622  RIG-I-like receptor signaling pathway
mbez04625  C-type lectin receptor signaling pathway
mbez04657  IL-17 signaling pathway
mbez04658  Th1 and Th2 cell differentiation
mbez04659  Th17 cell differentiation
mbez04660  T cell receptor signaling pathway
mbez04664  Fc epsilon RI signaling pathway
mbez04668  TNF signaling pathway
mbez04722  Neurotrophin signaling pathway
mbez04723  Retrograde endocannabinoid signaling
mbez04728  Dopaminergic synapse
mbez04750  Inflammatory mediator regulation of TRP channels
mbez04910  Insulin signaling pathway
mbez04912  GnRH signaling pathway
mbez04914  Progesterone-mediated oocyte maturation
mbez04917  Prolactin signaling pathway
mbez04920  Adipocytokine signaling pathway
mbez04926  Relaxin signaling pathway
mbez04930  Type II diabetes mellitus
mbez04931  Insulin resistance
mbez04932  Non-alcoholic fatty liver disease
mbez04933  AGE-RAGE signaling pathway in diabetic complications
mbez04935  Growth hormone synthesis, secretion and action
mbez04936  Alcoholic liver disease
mbez05010  Alzheimer disease
mbez05012  Parkinson disease
mbez05016  Huntington disease
mbez05017  Spinocerebellar ataxia
mbez05020  Prion disease
mbez05022  Pathways of neurodegeneration - multiple diseases
mbez05132  Salmonella infection
mbez05133  Pertussis
mbez05135  Yersinia infection
mbez05142  Chagas disease
mbez05145  Toxoplasmosis
mbez05152  Tuberculosis
mbez05161  Hepatitis B
mbez05162  Measles
mbez05166  Human T-cell leukemia virus 1 infection
mbez05167  Kaposi sarcoma-associated herpesvirus infection
mbez05169  Epstein-Barr virus infection
mbez05170  Human immunodeficiency virus 1 infection
mbez05171  Coronavirus disease - COVID-19
mbez05200  Pathways in cancer
mbez05208  Chemical carcinogenesis - reactive oxygen species
mbez05210  Colorectal cancer
mbez05212  Pancreatic cancer
mbez05231  Choline metabolism in cancer
mbez05415  Diabetic cardiomyopathy
mbez05417  Lipid and atherosclerosis
mbez05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mbez00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    129555633 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129555633 (MAPK8)
   04012 ErbB signaling pathway
    129555633 (MAPK8)
   04014 Ras signaling pathway
    129555633 (MAPK8)
   04310 Wnt signaling pathway
    129555633 (MAPK8)
   04668 TNF signaling pathway
    129555633 (MAPK8)
   04068 FoxO signaling pathway
    129555633 (MAPK8)
   04071 Sphingolipid signaling pathway
    129555633 (MAPK8)
   04024 cAMP signaling pathway
    129555633 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    129555633 (MAPK8)
   04137 Mitophagy - animal
    129555633 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    129555633 (MAPK8)
   04215 Apoptosis - multiple species
    129555633 (MAPK8)
   04217 Necroptosis
    129555633 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129555633 (MAPK8)
   04530 Tight junction
    129555633 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    129555633 (MAPK8)
   04621 NOD-like receptor signaling pathway
    129555633 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    129555633 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    129555633 (MAPK8)
   04660 T cell receptor signaling pathway
    129555633 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    129555633 (MAPK8)
   04659 Th17 cell differentiation
    129555633 (MAPK8)
   04657 IL-17 signaling pathway
    129555633 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    129555633 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    129555633 (MAPK8)
   04920 Adipocytokine signaling pathway
    129555633 (MAPK8)
   04912 GnRH signaling pathway
    129555633 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    129555633 (MAPK8)
   04917 Prolactin signaling pathway
    129555633 (MAPK8)
   04926 Relaxin signaling pathway
    129555633 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    129555633 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    129555633 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    129555633 (MAPK8)
   04722 Neurotrophin signaling pathway
    129555633 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    129555633 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129555633 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129555633 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    129555633 (MAPK8)
   05231 Choline metabolism in cancer
    129555633 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    129555633 (MAPK8)
   05212 Pancreatic cancer
    129555633 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129555633 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    129555633 (MAPK8)
   05161 Hepatitis B
    129555633 (MAPK8)
   05171 Coronavirus disease - COVID-19
    129555633 (MAPK8)
   05162 Measles
    129555633 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129555633 (MAPK8)
   05169 Epstein-Barr virus infection
    129555633 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    129555633 (MAPK8)
   05135 Yersinia infection
    129555633 (MAPK8)
   05133 Pertussis
    129555633 (MAPK8)
   05152 Tuberculosis
    129555633 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    129555633 (MAPK8)
   05142 Chagas disease
    129555633 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129555633 (MAPK8)
   05012 Parkinson disease
    129555633 (MAPK8)
   05016 Huntington disease
    129555633 (MAPK8)
   05017 Spinocerebellar ataxia
    129555633 (MAPK8)
   05020 Prion disease
    129555633 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    129555633 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129555633 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    129555633 (MAPK8)
   05415 Diabetic cardiomyopathy
    129555633 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    129555633 (MAPK8)
   04936 Alcoholic liver disease
    129555633 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    129555633 (MAPK8)
   04931 Insulin resistance
    129555633 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    129555633 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129555633 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mbez01001]
    129555633 (MAPK8)
Enzymes [BR:mbez01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     129555633 (MAPK8)
Protein kinases [BR:mbez01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   129555633 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 129555633
NCBI-ProteinID: XP_055281246
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctatcggttcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagtcggcca
tttcagaatcaaactcatgctaaacgtgcttacagagagctagttcttatgaaatgtgta
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatccctagaagaa
tttcaagacgtttatatagtcatggagctcatggatgcaaatctttgtcaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgactcgctactacagagcacctgaggtcatcctaggcatg
ggctacaaagagaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccccgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaattgatgcatctaaaaggatttctgtagatgaagctcttcagcacccgtat
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgagagggaacatacaatagaagagtggaaagaattgatatacaaagaagtt
atggacttggaagaaagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcatcatcatcttctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
gggcctctgggctgctgtagatga

DBGET integrated database retrieval system