KEGG   Moschus berezovskii (Chinese forest musk deer): 129555843
Entry
129555843         CDS       T09065                                 
Symbol
RYR2
Name
(RefSeq) ryanodine receptor 2
  KO
K04962  ryanodine receptor 2
Organism
mbez  Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez04020  Calcium signaling pathway
mbez04024  cAMP signaling pathway
mbez04260  Cardiac muscle contraction
mbez04261  Adrenergic signaling in cardiomyocytes
mbez04371  Apelin signaling pathway
mbez04713  Circadian entrainment
mbez04911  Insulin secretion
mbez04921  Oxytocin signaling pathway
mbez04972  Pancreatic secretion
mbez05020  Prion disease
mbez05022  Pathways of neurodegeneration - multiple diseases
mbez05410  Hypertrophic cardiomyopathy
mbez05412  Arrhythmogenic right ventricular cardiomyopathy
mbez05414  Dilated cardiomyopathy
mbez05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mbez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    129555843 (RYR2)
   04020 Calcium signaling pathway
    129555843 (RYR2)
   04024 cAMP signaling pathway
    129555843 (RYR2)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    129555843 (RYR2)
   04921 Oxytocin signaling pathway
    129555843 (RYR2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    129555843 (RYR2)
   04261 Adrenergic signaling in cardiomyocytes
    129555843 (RYR2)
  09154 Digestive system
   04972 Pancreatic secretion
    129555843 (RYR2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    129555843 (RYR2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    129555843 (RYR2)
   05022 Pathways of neurodegeneration - multiple diseases
    129555843 (RYR2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    129555843 (RYR2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    129555843 (RYR2)
   05414 Dilated cardiomyopathy
    129555843 (RYR2)
   05415 Diabetic cardiomyopathy
    129555843 (RYR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:mbez04040]
    129555843 (RYR2)
   04990 Domain-containing proteins not elsewhere classified [BR:mbez04990]
    129555843 (RYR2)
Ion channels [BR:mbez04040]
 Voltage-gated cation channels
  Ryanodine receptor
   129555843 (RYR2)
Domain-containing proteins not elsewhere classified [BR:mbez04990]
 EF-hand domain-containing proteins
  Other EF-hand domain-containing proteins
   129555843 (RYR2)
SSDB
Motif
Pfam: RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8
Other DBs
NCBI-GeneID: 129555843
NCBI-ProteinID: XP_055281718
LinkDB
Position
Unknown
AA seq 4970 aa
MADGGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPP
DLSICTFVLEQSLSVRALQEMLANTVEKSEGKVDVEKWKFMMKTAQGGGHRTLLYGHAIL
LRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDD
LILVSVSSERYLHLSYGNGSLHVDAAFQQTLWSVAPISSGSEAAQGYLIGGDVLRLLHGH
MDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHV
TTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSSKEKLDVGVRKEVDGMGTSEIKYGDSV
CYIQHINTGLWLTYQSVDVKSVRMGSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIR
STVFLFNRFIRGLDALSKKVKASTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLR
ALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADAAGREAGESWKSILNSLYELLAAL
IRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISL
LDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIF
LGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGD
DLFSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFE
NFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREY
KQERTYTRDLLGPTVSLTQAAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIEL
GWQYGPVRDDNKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAEEK
VKKMKLPKNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGI
QQDVKNRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYGYNLEAPDQDHAARAEVCSG
TGERFRIFRAEKTYAVKAGQWYFEFEAVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGF
KAQRWHQGNEHYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELAFKDFDVGDG
FIPVCSLGVAQVGRLNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQ
VPSNHEHIEVTRIDGTIDSSPCLKVTQKSFGSQNSSTDIMFYRLSMPIECAEVFSKTAAG
GIPGTGLFGPKNDLEDYDVDSDFEVLMKTAHGHLVPDRGDKDKEATKPEFNNHKDYAQEK
PSRLKQRFLLRRTKPDYSTSHSARLTEDVLADERDDYDYLMQTSTYYYSVRIFPGQEPAN
VWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESLSPGQGR
NNNGLEIGCVVDAASGLLTFTANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRI
KNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQ
CVEPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNHRVAHALCSHV
DEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETKSITLFP
DENKKHGLPGIGLSTSLRPRMQFSSPSFVSINTEGYQYSPEFPLDILKAKTIQMLTEAVK
EGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGVFHNEDLKHVLQLIEPSVFKEAASPEEE
SEVAEKEPCVEDSKLEGAAEEENKAGSRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRH
RIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFK
DDKSECPCPEEIRDQLLDFHEDLMTHCGIELDEDRSLDGNNDLTIRGRLLSLVEKVTYLK
KKQAEKPVESDSKKSSTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVR
ALPKTYTINGVSVEDTISLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPN
LMRALGMHETVMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSY
LLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQML
VSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGG
NGLLAAMEEAIKIAEDPSRDGPSPTMGSSKTPDTEEEEDDTIHMGNAIMTFYAALIDLLG
RCAPEMHLIHAAKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGNVVEPDMSAGF
CPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYL
CTAVLPLLTRCAPLFAGTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQL
RPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHL
SRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEKQSSMDSEGN
FNPQPVDTSNITIPEKLEYFINKYAEHAHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPY
KLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQVSVDAAHG
YSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKLELEAKGGGNHPLLVPYDTLTAK
EKAKDREKAQDILKFLQINGYAVSRGFKDLELDTPSIEKRFAYSFLQQLIRYVDEAHQYI
LEFDGGSRSKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCSGGHASNKE
KEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLESVKSALRAF
LDNAAEDLEKTMENLKQGQFTHTRNQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGED
LILEDVQVSCYRILTSLYALGTSKSIYVERQRSALGECLAAFAGAFPVAFLETHLDKHNI
YSIYNTKSSRERAALNLPTNVEDVCPNIPSLEKLMEEIVDLAESGIRYTQMPHVMEVILP
MLCSYMSRWWEHGPENNPGRAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLA
VFSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVVSEEDHLKSEARGDMSEAELLILDEFT
TLARDLYAFYPLLIRFVDYNRAKWLKEPNQEAEDLFRMVAEVFIYWSKSHNFKREEQNFV
VQNEINNMSFLIMDTKSKMSKAAVSDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNI
CAPGDQELIALAKNRFSLKDTEDEVRDIIRSNIHLQGKLEDPAIRWQMALYKDLPNRTED
TSDPEKTVERVLDIANVLFHLEQKSTCMRRRYYNLGSTVEHPQRSKKAVWHKLLSKQRKR
AVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPGAEPPEDDEG
TKRVDPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCHDEEDDDGEEEVKSFEEK
EMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKM
LDYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVLQDDEFTC
DLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDV
IDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMK
LSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFF
DMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENET
LDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIE
IMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTI
FEMQLAAQISESDLNERSANKEESEKEKPEEQGPRMGFFSIVTVKSALFALRYNILTLMR
MLSLKSLKKQMKKVKKMTVKDMITAFFTSYWGVLMSLLHFVASVFRGFSRIIGSLLLGGS
LVEGAKKIKVAELLANMPDPTQDEVRGDGEEGERKTLEGALPSEDLTDLKELTEESDLLS
DIFGLDLKREGGQYKLIPHNPNAGLSDLMSNPVPIPEVQEKFQEQKAKEEEKEEKEESKS
EPEKAEGEDGEKEEKAKEDKGKQKLRQLHTHRYGEPEVPESAFWKKIIAYQQKLLNYFAR
NFYNMRMLALFVAFAINFILLFYKVSTSSVVEGKELPTRSSSENAKVSSLDSSSPRIIAV
HYVLEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYI
TEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAAL
DFSDAREKKKPKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSILGHYNNF
FFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSE
DGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVI
LLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLAN
YLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN
NT seq 14913 nt   +upstreamnt  +downstreamnt
atggccgatgggggcgagggcgaggatgagatccagttcctgcgaactgatgatgaagtg
gtcctacagtgtaccgcaaccatccacaaagaacaacagaaactatgtttggcagcagaa
ggatttggcaacagactttgcttcttggagtccacttcgaattccaagaatgtccctcca
gacctctccatctgcaccttcgtgctggagcagtccctgtctgtccgggccctgcaggag
atgctggctaacactgtggaaaagtctgaagggaaggttgatgtggaaaaatggaaattc
atgatgaagactgctcagggtggtggccaccggacgctcctctacggtcatgcaatactg
ctgcggcattcctacagtggcatgtacctgtgctgcctgtccacctctcggtcttcaact
gataagctggcttttgatgttggcttgcaagaggatacaacaggtgaagcttgttggtgg
accatccatcctgcctctaagcagcgttcagaaggagaaaaagtgcgggttggagatgac
ctcatcttagtgagcgtgtcctctgaaaggtacctgcacttgtcttacggtaacggcagc
ttgcacgtggatgctgctttccagcagaccctctggagcgtggccccaatcagctcagga
agtgaagcagcccaagggtatctgattggtggtgacgtcctcaggttgcttcatggacac
atggatgaatgcctcactgtcccttcaggagaacacggtgaagagcagcggagaactgtt
cattacgaaggtggtgctgtatcggttcacgcacgttccctgtggcgactagagacacta
agagttgcgtggagtggaagccacataaggtggggacaaccttttcgactacgccatgtc
acaacaggaaaatacttgagtctcatggaagacaaaagccttctactcatggacaaagaa
aaagctgatgtcaaatcaactgcgtttaccttccggtcttccaaggaaaaattggatgtg
ggagtgagaaaagaagttgatggcatgggaacctctgaaataaaatatggagattcagta
tgttacatacagcatatcaatacaggcttgtggctaacttaccagtctgtggatgtgaaa
tcagtgagaatgggatccatacaacgtaaggctattatgcatcatgaaggacacatggat
gatggcctaaatttatccagatctcagcatgaagaatcacggacagcacgtgtcatccgg
agcacagtcttcctttttaatagatttattaggggccttgatgctctcagcaaaaaggtg
aaggcttccacagtagacttacctatagagtctgtaagtctgagtctgcaggaccttatt
ggctacttccacccaccagatgagcatttagagcatgaagataaacagaacagattacgg
gctctgaagaacaggcagaatctcttccaggaagagggaatgatcaaccttgtgctcgag
tgtatagacaggctgcatgtgtacagcagtgctgcccacttcgctgatgctgctgggaga
gaagcaggggaatcttggaaatcgattctgaattctctgtatgagttgctggcggcacta
attagaggaaatcgtaaaaactgtgctcaattttctggctcccttgattggttaatcagt
cgactggaaagactggaagcttcttctggtattcttgaagttttacactgtgtgttagta
gaaagtccagaagctctaaatattattaaagaaggccatataaaatccattatctcactt
ttagacaagcatggaagaaatcacaaggttctggatgtcttatgctctctctgtgtttgc
catggagtagcagtccgttctaaccagcatctcatttgtgacaatcttctgccaggaaga
gatctgttattgcagacacgccttgtgaaccatgtaagcagcatgagacccaatattttt
ctgggtgtcagcgaaggatctgcacagtataagaagtggtattatgagttgatggtggac
catactgagccgttcgtgactgctgaagccactcacctgcgagtgggctgggcttccaca
gaggggtactcaccctaccctggagggggtgaagagtggggtggaaatggtgttggagat
gacctcttctcctacggatttgatggccttcacctctggtcaggttgtattgcccggact
gtcagctcaccaaaccagcatctcttgagaactgatgatgtcatcagttgctgtttagat
ctaagtgccccaagcatctccttccgaattaatggacaacctgttcaaggcatgtttgag
aatttcaacattgatggcctcttctttccagttgtcagtttctctgcaggaatcaaagta
cgctttctgcttggggggcgacatggagaatttaaattcctccctccgcctgggtatgct
ccttgttatgaagctgttctgccaaaagagaagttgaaagtggagcacagccgagagtac
aagcaagagaggacttacacgcgggacctcctgggccccacggtttccctgacacaagct
gccttcacaccaatcccagtggacaccagccagattgtgttgcctccccacctggagagg
atacgagaaaaattagcagagaatatccatgagctctgggtgatgaataaaattgaactt
ggctggcagtatggtccggttagagatgacaataagagacagcacccgtgtctggtggag
ttctccaagctgcctgaacaggaacgcaattataatttacagatgtcgctggagaccctg
aagacattgttggctttaggatgtcatgtgggcatatcagatgaacacgctgaagaaaag
gtgaagaaaatgaagctgccaaagaattaccaactgacaagtggatacaagcctgcccca
atggacctgagctttatcaaactcaccccatctcaggaggctatggtggacaagttggcg
gaaaatgctcataatgtgtgggctcgggatcgaattcgacagggctggacctacggcatc
caacaggatgtaaagaacagaagaaaccctcggcttgttccctatgcccttctagatgac
cgaactaagaaatccaataaggatagcctccgcgaggctgtgcgcacactgctggggtat
ggctacaacctggaggcacccgatcaagatcacgctgccagagccgaagtgtgcagcggc
acaggagagcggttccgcatcttccgtgctgagaagacgtatgctgtgaaggctggacag
tggtattttgaattcgaggcggtcactgctggagacatgcgagttggctggagcaggcca
gggtgtcaacctgatcaggagcttggctcggatgaacgtgcctttgcttttgatggcttc
aaggcccagcggtggcaccagggcaatgagcactatgggcgctcttggcaagctggcgat
gttgtggggtgtatggttgacatgacagaacacaccatgatgttcacactgaatggcgaa
atccttcttgatgattcaggttcagaactggctttcaaggactttgatgttggtgatgga
ttcatacctgtgtgtagcctgggagtggctcaagtgggcaggctgaactttggaaaggat
gtcagcaccttgaaatatttcaccatctgtggcttacaagagggctatgagccatttgcc
gttaacacaaatagggatattaccatgtggctgagcaagaggcttcctcagtttctccaa
gttccatcaaaccatgaacatattgaggtgaccagaatagatggcaccatagacagttcc
ccatgtttaaaggtcactcagaagtcttttggctctcagaacagcagcacggatatcatg
ttttatcgtctgagcatgcccatcgagtgtgcagaggtcttctccaagactgcagctgga
gggatccctggcaccggcctctttggacccaagaatgatctggaggattatgatgtggat
tcggactttgaggttctcatgaagacagctcatggccatctggtgccagatcgaggagac
aaagacaaagaagctacaaaaccagagtttaataaccacaaagattatgctcaggaaaaa
ccctctcgtctgaaacagaggtttttgcttcgaagaacaaagccagattatagcaccagc
cattctgcaagactcactgaagatgtccttgcagatgagagggatgactacgattacttg
atgcagacgtccacgtactattactcagtgagaatctttcctggacaagaacctgccaat
gtctgggtgggctggatcacatctgatttccatcagtatgatacaggctttgacttggac
agagttcgtacagtgaccgtgactctgggagatgaaaaaggaaaggtgcacgaaagcatc
aaacgcagcaattgctatatggtgtgtgcgggtgagagcctgagcccggggcaaggacgc
aacaacaacggcttggagattggctgcgtggtggacgccgccagtgggctgctcaccttc
acggccaacggcaaggagctgagcacctattatcaggtggaaccaagcacaaaattattt
cctgcagtttttgcacaagctacaagtcccaatgtttttcagtttgagttgggaagaata
aagaatgtgatgcctctctcagcgggattattcaagagtgagcacaaaaatcctgtgcca
cagtgtcccccacgtctccatgtgcaatttctctcacacgtcctgtggagcagaatgccc
aaccagttcttgaaggtagatgtctctcgaataagtgaacgccagggctggctggtgcag
tgcgtggagcctctgcagttcatgtcacttcatatcccagaggagaacagatccgtggac
atactggaactgaccgagcaggaggaactgctgaagttccactaccacacgctccggctc
tactcggccgtctgcgcgctcgggaaccaccgggtggcccacgccttgtgcagccacgtg
gacgaaccgcagctgctctacgccatcgagaacaagtacatgcccggcttgctgcgcgcc
ggctactacgacctgctgattgacatccacctcagctcctacgccaccgccagactcatg
atgaacaacgagttcatcgtgcccatgaccgaggagacgaagagcatcaccctcttcccg
gatgagaacaaaaagcacgggctcccgggcatcggcctcagcacctccctcaggccgcgg
atgcagttttcctccccgagtttcgtcagcattaataccgagggttaccagtacagcccg
gagttcccgctggacatcctgaaggccaagaccatacagatgctgacggaagccgtgaaa
gagggcagcctgcacgcccgagaccccgttgggggcaccactgagttcctcttcgtccct
ctcatcaagctcttctacaccctgctcatcatgggtgtcttccacaacgaggacttgaaa
cacgtcttgcagttgattgagcctagtgtgttcaaggaagccgccagccccgaggaggag
agtgaggtggcagagaaggagccctgcgtggaagactccaagctggaaggagccgcagag
gaagaaaacaaagcgggttcgaggcccaaggagggcctgctccaaatgaaactgccggag
ccagtaaaattgcagatgtgcctgctacttcaatacctctgtgactgccaggtccggcac
cggatagaagccattgtggccttttcagatgactttgtagccaagctccaagacaatcaa
cgattccgatataatgaagttatgcaagccttaaacatgtcggctgcactcacagccagg
aaaacaaaggaattcagatccccgcctcaagaacagatcaatatgcttctcaattttaag
gatgacaaaagtgaatgtccatgtcctgaagaaatccgagaccaactcttggattttcat
gaagatttgatgacacattgtggaattgagctggatgaagataggtctctggatggaaac
aatgatttaactattagaggacgcctgctgtccttggtagaaaaggtgacatacctgaag
aagaagcaagctgaaaagccagttgagagtgactccaagaagtcatccactcttcagcag
ttgatttctgagaccatggtccgatgggctcaagagtctgttattgaagaccctgagttg
gtgagggccatgtttgtattgctccatcgacagtatgatggcattgggggtctggtacgg
gctctgccaaagacctacactataaatggtgtctctgtggaggataccatcagtctgctg
gcatctcttggtcagattcgttctctgctaagtgtgagaatgggcaaagaggaagagaaa
cttatgattcgtggattaggggatatcatgaacaataaagtgttttaccagcatcctaat
ctcatgagggcacttgggatgcatgagacagtgatggaggtcatggtgaatgtccttgga
ggtggagagtccaaggaaatcacttttccgaagatggtggccaactgttgccgttttctc
tgttacttctgtcgtataagtaggcagaatcagaaagctatgtttgatcatctcagttat
ttactggaaaacagcagtgttggtcttgcctcaccagctatgagaggttcaacaccactg
gatgtggcagcagcctcggtgatggataataatgaactagctttagctttgcgggagcca
gatctggaaaaggtggttcggtatttggctggttgtggattgcagagttgccagatgcta
gtgtcaaagggttatccagacattgggtggaatccagttgaaggagagagatatcttgac
tttctcagatttgctgtcttctgtaatggggaaagcgtggaggagaatgcaaatgtcgtg
gtgagattgctcatccggaggcctgagtgtttcggtcctgccttgaggggggaaggtggg
aatggcctgctcgcagccatggaagaagccataaaaatagccgaggatccctctcgagat
ggtccctcaccaactatgggatccagcaaaacccctgatacagaagaggaagaggatgat
accatccacatgggaaatgccatcatgaccttttatgcagctttgattgacctgttagga
cgctgtgctcctgaaatgcatttgattcatgctgccaagggagaagccatcagaatcagg
tctattttgagatctctgattccattgggagatttggtgggagtaatcagcatcgctttt
cagatgcccacaatagccaaagatgggaatgtggtggagcctgacatgtctgcagggttt
tgtccagatcacaaggcagccatggttttgttccttgacagggtctatggaattgaggtt
caagatttcctcctccatcttctcgaggttggctttctgccagatctccgggctgctgct
tccttagacacggctgctttgagtgctacagacatggccctggccctcaatcggtacctg
tgcacagccgtgttgcccttgttaacaaggtgcgctcctctgtttgctggcactgagcac
catgcttctctcattgactcattactgcacactgtgtacaggctttctaagggctgctca
ctcaccaaagcgcaacgggattccatagaagtgtgtttactctctatttgtggccaattg
agaccgtctatgatgcaacacttactcagaagattagtatttgatgtcccattattaaat
gaacatgcaaagatgcctcttaagctgctgacaaatcattatgaaagatgctggaaatat
tactgcctgcctggagggtggggcaactttggagctgcctcagaagaagaacttcattta
tcaagaaagctgttctggggcatctttgatgccctgtctcaaaagaaatatgaacaagaa
cttttcaaactggcactgccttgcctgagtgcagttgcgggagctttgcctccagactac
atggagtcaaattatgtcagtatgatggaaaaacagtcatcaatggattctgaagggaac
tttaatccacaacctgttgatacctcaaatattacaattcctgagaagttggaatacttc
attaacaaatatgcagaacatgcccatgacaagtggtcaatggataagttggcaaatgga
tggatttatggagaaatatattcagactcatctaaagttcaaccattaatgaagccatat
aaactgctatctgaaaaggaaaaagaaatttatcgctggccaatcaaagaatctttaaaa
accatgctggcttggggatggagaattgaaaggacacgagagggagacagcatggccctt
tataaccgtactcgtcgtatttctcagacaagtcaggtttctgtagatgccgcccatggg
tacagcccacgagccattgacatgagcaatgttacactatccagagatctgcacgcaatg
gcagaaatgatggctgaaaactaccataatatatgggcaaagaaaaagaaactggaactg
gaggccaaaggaggtggaaaccatcccctactggtaccttatgatacactgacggccaaa
gagaaagccaaagatagggaaaaagcacaggacatcctcaagttcctgcagatcaatggc
tatgctgtatccagagggttcaaagacctagaactggacacaccttctattgagaaacga
tttgcctatagtttccttcagcaactcattcgctatgtggacgaggcccatcagtatatc
ctggagtttgatggtggcagcagaagcaaaggagaacatttcccttatgaacaagaaatc
aagttctttgctaaagtcgttcttcctttaattgatcagtatttcaaaaaccaccgttta
tacttcttatctgcagcaagcagacctctctgttctggaggacatgcatcaaacaaagag
aaagaaatggtgactagcctattctgcaaacttggagttcttgtcaggcataggatttca
ctatttgggaatgatgcaacatcaattgtcaactgtcttcatattttgggtcagactttg
gatgcaaggactgtgatgaagactggcctggagagtgttaaaagtgcactcagagccttt
ctggacaatgccgcagaggatctggagaagacgatggagaatcttaagcagggccagttc
acccacacccgaaaccaacccaaaggtgttactcagattatcaattataccacggtggca
ctgttgccaatgctgtcatcattatttgagcatattggccagcatcaattcggagaagat
ctaatattggaagatgtacaggtgtcatgttatagaattctgactagcttgtatgctttg
ggaaccagcaagagtatttatgtggaaaggcaacgttctgcattgggagaatgtctggct
gcttttgctggtgcctttcctgtagcatttttggaaactcacctggacaagcacaatatt
tactccatctacaatacaaagtcttcgagagagagagcagctcttaatttgcctactaac
gtggaagatgtttgtccaaatataccgtctttggagaagctcatggaagaaattgtggac
ttggctgagtccggtattcgctacacacagatgccacatgtgatggaagttatcctgccc
atgctttgtagctacatgtctcgctggtgggaacatggacctgagaataatccaggaagg
gctgagatgtgctgtacggctctgaactcagagcacatgaacacactgctgggcaatatc
ctgaaaatcatatataataacttgggtattgatgagggagcctggatgaagaggttagca
gtgttttcccagcctattatcaataaagtgaaacctcagctattgaaaactcatttcttg
ccattaatggagaagctcaagaaaaaggcagcgatggtggtatcagaagaggaccatctg
aaatctgaggccaggggagatatgtctgaagccgaacttctcattctagatgagttcacc
acactggccagagatctctatgccttctatccactcctgattagatttgtggactataac
agggcaaagtggctgaaagagcctaaccaagaagcagaagatcttttccgcatggttgct
gaggtgtttatctactggtcaaaatcccataatttcaaaagggaggagcaaaactttgtg
gtgcagaatgaaatcaacaatatgtctttccttattatggacaccaagtcaaagatgtcc
aaggcagctgtttctgatcaggaaaggaagaaaatgaagcgcaaaggggaccgatattcc
atgcagacctctcttattgtggctgctctgaagcggttactgcctattgggttgaacatc
tgtgcccctggggaccaggagctcattgctctggccaaaaatcgctttagtctgaaagac
actgaggatgaagttcgagatataatccgcagtaatattcacttacaaggcaagttggag
gatcctgctattagatggcaaatggctctttacaaagacttacccaacaggacagaagac
acttcagatcctgagaagacagtggaaagggtcttggatatagcaaatgtgctttttcat
cttgaacagaaatctacatgtatgcgccggagatattacaatctgggaagtacagttgag
catcctcagagatcaaaaaaggccgtatggcacaaactgctctctaagcagaggaaacgt
gccgtggttgcttgcttccggatggctcctttatataatctgccgaggcatcgggctgtc
aatctctttcttcagggatatgaaaagtcttggattgagacagaagaacattactttgaa
gataaattgatagaagacttagcgaaacctggagcagaacctccagaagatgatgaagga
actaagagggttgatcctcttcatcagctgatccttctgtttagtcgaacagctttaacg
gagaaatgcaaactggaggaagattttttatatatggcttatgcagatattatggcaaag
agttgtcatgatgaggaagatgatgatggggaagaggaagtgaagagttttgaagaaaaa
gaaatggaaaagcaaaagcttctttaccaacaagccaggctccacgaccgcggtgctgct
gagatggtgctgcaaaccatcagtgccagcaaaggtgaaactggacccatggtggctgct
actttgaaacttggaattgctatcttaaatggaggcaactctacggtacagcagaaaatg
cttgactacctcaaggagaaaaaggatgtgggcttctttcagagcctggctggcctgatg
cagtcatgcagtgtcctcgacctaaatgcatttgagcgacaaaacaaagctgaaggactt
gggatggtgactgaggaaggatcaggagaaaaggttctgcaagatgacgaattcacctgt
gacctcttccgcttcttgcaactgctttgtgagggacacaactcagattttcaaaattat
ctgagaactcagactggcaataatacaactgtcaacataatcatctctactgtagactac
cttctgagagttcaggaatcaattagtgatttctattggtattattctgggaaagatgtc
attgatgaacaaggacaaaggaatttctccaaagctattcaagtggcaaaacaagtcttt
aacactcttacagagtatattcagggtccctgcactggcaaccagcagagtctggctcac
agcaggctctgggatgctgtggtgggttttctgcacgtatttgcccacatgcagatgaag
ctgtcgcaggactccagtcaaattgagctactaaaagaattgatggatcttcagaaggac
atggtggtcatgttgctgtccatgttggaaggcaatgttgttaatggcaccattggcaaa
cagatggttgatatgctcgtggaatcttccaacaacgtggagatgattctcaagtttttt
gacatgttcttaaaactcaaggacttgacatcgtctgatactttcaaagagtatgacccc
gatggtaagggagttatttccaagagggactttcacaaagccatggagagccataaacac
tacacccagtccgagactgagtttctcctatcctgtgcagagacagatgaaaatgaaacc
ctggactatgaagaatttgtcaaacggttccatgagcctgccaaggacattggcttcaac
gtggcagtgcttctgacaaacctctccgaacacatgcccaatgacacccggctgcagact
tttctggaattggccgagagcgtgctcaattacttccagcccttcctgggccgcatcgag
atcatgggcagtgccaagcgcatcgagagggtgtattttgaaatcagtgagtccagccga
acccagtgggagaaaccccaggtcaaggagtccaaaagacaatttatatttgacgtggtc
aatgaaggcggggagaaagagaagatggagctcttcgtgaacttctgcgaggacaccatc
tttgagatgcagctggcagctcagatatcagagtcagatctgaacgagaggtcagcgaat
aaagaggagagtgagaaggagaagcctgaggagcagggtccgaggatgggtttcttttcc
atcgtgacggtcaagtctgccctgtttgccctcaggtataatatcttgacccttatgcgg
atgctcagcctgaaaagcttgaagaagcagatgaagaaggtgaagaagatgacagtgaag
gacatgatcacagccttctttacatcctactggggtgttctgatgagcctcctgcacttt
gtagccagcgttttcagaggcttctctcgcatcattggcagcctcctgctgggaggaagc
ctggtcgaaggtgcgaagaagatcaaagtggcggagctcttggccaacatgccagacccc
acacaggatgaggttcgaggagacggggaggagggagagaggaaaaccctggaaggggcc
ctgccctctgaagatctgacggacttgaaggaactgacagaagagagtgacctgctgtct
gatatctttggcttggacctgaagcgagaaggagggcagtacaaactgattcctcacaat
cccaatgctggcctgagtgacctcatgagcaaccccgtccccattccagaggtgcaagaa
aagttccaggaacagaaggcaaaagaagaagaaaaggaagaaaaagaagaaagcaaatcc
gaacccgagaaagctgaaggagaagatggagaaaaagaagaaaaagccaaagaagacaag
ggtaaacaaaaactgaggcagctccacacacacagatatggagaaccagaagttcctgag
tcagcattctggaagaaaatcatagcctatcaacagaaacttctaaactattttgctcgc
aacttctacaacatgagaatgttagccttatttgtcgcatttgcaatcaatttcatcttg
ctcttttataaggtctccacttcttctgtggttgaaggaaaggaactacccactcgcagt
tcaagtgaaaatgccaaagttagcagcttggacagcagctcgcctagaatcatcgcagtg
cactatgtgttggaggagagcagtggctacatggagcccacactgcggatattagccatt
ctgcacacggtcatctctttcttctgcatcattggatactactgcttgaaagtcccactg
gttatttttaagcgagaaaaggaagtagctcgaaaattggaatttgatgggctttatatt
acagaacagccttcagaagatgatattaaaggccagtgggatagactcgtaatcaacaca
cagtcatttcccaacaactactgggacaaatttgttaaaagaaaggttatggataaatat
ggagagttctatggccgagacagaatcagtgagttacttggcatggacaaagctgccttg
gacttcagtgatgcccgggaaaagaagaagccaaagaaagacagctccctgtcagctgta
ctgaactctattgatgtgaagtatcagatgtggaaactaggagtcgttttcactgacaac
tccttcctctaccttgcctggtatatgaccatgtcaattcttggacactacaacaacttt
ttttttgctgctcatcttctggacattgctatgggattcaagacattaagaaccatcttg
tcatcagtaactcacaatggcaaacagcttgtattaactgttggcttattggctgttgtt
gtatacctatatactgtcgtggcattcaattttttccgaaaattctacaataaaagtgaa
gatggcgatacaccagacatgaaatgtgatgacatgctaacatgctatatgttccacatg
tatgttggagtacgtgccggagggggtatcggtgatgaaatcgaagatccagctggtgat
gaatatgagatatatcgaatcatctttgacatcaccttcttcttttttgtaattgtcatt
ctcttggccataatacaaggtttaatcatcgatgcttttggggaactaagagaccaacag
gaacaggtcaaagaagacatggagaccaagtgcttcatctgtgggataggcaatgattac
tttgacactgtgccacatggctttgaaacccacactttacaggaacacaacttggccaat
tatctgttttttctgatgtatctcataaacaaagatgaaacggagcacacaggacaggaa
tcttatgtttggaagatgtatcaagaaaggtgctgggaatttttcccagctggagactgt
ttccggaaacagtatgaagaccagctaaattaa

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