Moschus berezovskii (Chinese forest musk deer): 129559595
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Entry
129559595 CDS
T09065
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mbez
Moschus berezovskii (Chinese forest musk deer)
Pathway
mbez00310
Lysine degradation
mbez01100
Metabolic pathways
mbez05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mbez00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
129559595 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
129559595 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mbez03036
]
129559595 (DOT1L)
Enzymes [BR:
mbez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
129559595 (DOT1L)
Chromosome and associated proteins [BR:
mbez03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
129559595 (DOT1L)
HMT complexes
Dot1-containing complex
129559595 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
129559595
NCBI-ProteinID:
XP_055287485
LinkDB
All DBs
Position
Unknown
AA seq
1714 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVVFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTPVDSGAEEEKAGTATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAT
NPERKPKKTQSALDLLHAQTVSRAASPLPQDAHRPPHSPFYQLPPSVQRPTPEQLLLAPT
PPALHRLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGNRELRSQSLRLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDEALALQLRGKPEAEPGRLHLELDCARFSLPPFSSLSPELSMNGHAAGYELCGTL
GRPSPKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSSLALPDYTRLSPAKLVLRRHLS
QDHAASGKAAASELHPRAEHAKENGLPCQSPGVTNGIKLSPQDPQPSSPMALQIGEKGPE
KGVKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKARSTPSPGPPA
RESSSTLEKQVAANAHGAGGNTAGSKSLTLAPTGFAYTGSVAISGALAGSPAPLGPGAEP
PALDESSSSGSLFATVGSRSSTPQHPPLLTQPRTCGSASPAPQLCTSPRLGALGPLPDSG
KGDLPCEASFSDPESEAKRRIVFTISAGASSAKQSPSSKHSPLPSGTRGDSGQGHGPDSR
KRGRRKRASAGTPSLSSSVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAIS
SPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKI
ATISLESKSPPKTLENAGGSLAGRKAPLASEPVNSSKWKSTFSPISDLGLAKAADSPLQA
ASALSHNSLFTFRPGLEEPSVADAKLATHSRKSFPGTLPGAGGLSPSSLPASGFALGGGL
ATDLSLHSFSDGASLSHKAPEAAGLGAPLSFPGPRGKEAGAAESGPFTNKRQLDGLGSKG
EGGLPTCGPPDKASTAHSKAGKGREREPDVKNGHNLFMAAAAAPPAGLLSGPGLAPAASL
AGGAAPSVQTHRPFLGTFAPGPQFALGPMSLQANLGPSVLQSLFSSVPAAGLVHVSTAAT
RLTNSHAMSSFSSGVAGGAVGGVFNHAVPPASAHPFGASFGSGAACRSTTLNLTPLQPVA
STPASSFQAPSSAEPRPPPLPPHLGRPPPGQPTLHAPAHPNATLPPPPALLPANSEPVLL
QNLASLPANQAFLPTSSAASLPPANASLSIKLASLPHKVSRPSLTVHHQPLPGLALAQAA
PVNPQASSTGPPAVWVSLGMPPPYAARLAGVKPR
NT seq
5145 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccatggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atcagatgggtctgtgaagaaatcccggatctcaagcttgctatggagaactacgtttta
attgactacgatactaaaagctttgagagtatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggcaccacacagcccatgaagctgaacacg
cggccgtccacggggctcctgcggcacatcctgcagcaggtctacaaccactcagtgacc
gaccctgagaagctcaacaactatgagcccttctccccagaggtgtatggggagacctcc
ttcgacctggttgcccagatgatcgatgagatcaagatgaccgaagatgacctgttcgtg
gacctgggcagtggggtgggccaggtcgtgctgcaggttgccgcggccaccaactgcaaa
catcactatggtgtagagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggagagg
ggggacttcctctcggaggagtggagagaacggattgctaacacaagtgttgtatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaagccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacattggcaccataatgcgcgttgtggagctgtcgccgctgaaa
ggctccgtgtcgtggacggggaaaccagtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctaaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgggagaacaagagcaacacaaccacgcccaccaaggtgccc
gagagcaaggcagctgtgccagcggacacgcccgtggactccggtgccgaggaggagaaa
gccgggacggccactgtcaagaagccatctccctccaaggcccgaaagaagaagctgaac
aagaagggccggaagatggcaggtcggaagcgcgggcgccccaagaagatgagtgccacc
aaccccgagcgcaagcccaagaagacccagagcgcactggacctgctgcacgcccagacc
gtgtcgcgagcggcctcccccttgccgcaggacgcgcacaggccacctcacagcccattc
taccagctacctcccagcgtgcagcggcctacccctgagcagctgctgctggcacctacc
ccacctgcactgcacaggctgctagagtccttcaagattcagtacctacagttcctggca
tacacaaagacccctcagtacaaggccaacctgcagcagctgctagaccaggagaaggag
aagaatgcccggttgcttggcgcagcacagcagctgttcggccactgccaagctcagaag
gaggagatcaagaggctcttccagcagaaactggacgagctgggagtgaaggcgctgacc
tacaacgacctgatccaagcgcagaaggagatctcagctcacaaccagcagttgagggag
caaacggagcagctggagaagggcaaccgggagctgaggagccagagcctgcggctgctc
aaggcacggtgtgaggagctgaagctggactggtccacactgtccctggagaatctgtta
aaggagaagcaggccctgaagagccagatctcagagaagcagaggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagttgctgcagctcaag
tcctgtgtgccgcctgatgaggcactggccctgcagcttcgtgggaagccagaggccgag
cctggccggctgcacttggagctggactgcgcccggttctccctgccacccttcagcagc
ttgagccccgagctctccatgaatggccacgcggccggctatgagctctgcggtacactg
ggtcggccctcgcccaagcagaacaccccccagtacctggcctccccactagaccaggag
gtcgtgccctgcacccctagccacagtggccggccacggctggagaagctgtccagcctg
gccctgcccgactacaccaggctatcccctgccaagctggtgctgcggcgccacctgagc
caggaccacgcggccagcggcaaggcagctgccagtgagctgcacccacgagccgagcat
gccaaggagaacgggctcccttgccagagccctggcgtcaccaatggcatcaagctgagc
ccacaagacccccagccttcatcccccatggctttacagatcggagagaagggccctgag
aagggtgtgaaggagcgtgcctacgccagcagtggggaggccatcaccagcctgcccgtc
agcatcccgctgagcaccgtgcagcccagcaagctgcccgtcagcatccccctggccagc
gtggtgctgcccagccgcgccgagaaggcgagaagcacacccagccctgggccacctgcc
cgagagtcctcgtccacgctggagaagcaggtggctgctaacgcccatggtgccgggggc
aacactgccgggagcaagagcctcaccctggctcccacaggctttgcatacaccggctcg
gtggccatcagtggggccctggcgggcagcccggcacccctcggccctggagctgagccc
ccggccctcgacgagtcctccagctctggaagcctctttgccactgtggggtcccgcagc
tccactccgcagcacccacccctgctaacgcagccacgcacctgcggctcagcctcacca
gccccccagctctgcaccagcccccggctaggcgccctgggcccgctccccgactctggc
aaaggggacctgccctgcgaggccagcttctcagaccctgagagcgaagccaaaaggagg
atcgtcttcactatctcagcgggtgccagcagcgccaagcagtcaccttccagcaaacac
agccctctgccctcgggtacccgcggggacagtggccagggccacgggccagacagccgc
aagcggggccggaggaagcgagcatcggcggggacccccagcctgagctcgagtgtgtcc
cccaagcgccgggccttgccatctgttgctgggcttttcacacagtcttcagggtccccc
ctgaacctcaactccatggtcagcaacatcaaccagcccctggagatcacggccatctca
tcccctgagagctccctaaagagctcacccgtcccttaccaggacaacgaccaaccaccc
gtgctcaagaaggagaagcccctgagccagaccaatggtgcccactactccccgctgacc
tcggatgaggagccaggttctgaggatgaacccagcagcgccagaattgagagaaaaatt
gcaacgatctccttagaaagcaagtctccaccaaaaaccttggaaaatgcaggtggcagc
ctagcaggaaggaaggcaccgctggccagcgagccagtcaacagcagcaagtggaagtcc
accttctcgcctatctccgacttgggcctggccaaggcggccgacagcccgctgcaggct
gcctctgctctgagccacaactccctgttcactttccggcccggcctggaggagcccagt
gtggccgatgccaagctggccacccactccaggaagagcttcccgggcacgctgccaggg
gcgggcgggctgagccccagtagccttcctgccagtggcttcgccctgggcgggggccta
gcaactgacctcagtttacacagcttcagtgatggtgcttctctctcccacaaggccccc
gaggcagctggcctgggtgcccccctgagcttccccggcccacggggcaaggaggctggc
gccgcagagtctggccccttcacaaacaagcggcagctggacggactgggctcaaaaggc
gaggggggccttcccacatgtggacccccggacaaggcctcgacagcgcatagcaaggca
ggcaagggccgtgagcgtgagcctgacgtcaagaacggccacaacctgttcatggctgcc
gctgccgcaccccctgcaggcctcctcagcggcccaggtcttgccccagcggcatccttg
gcaggtggcgcagccccgtccgtgcagacccaccgccccttcctgggcaccttcgcccct
gggccacagttcgcactgggccccatgtcgctacaggccaacctgggcccgtctgtgctg
cagtccctgttcagctccgtgcccgccgccggcctggttcatgtctcgaccgccgccacc
agactgaccaactcgcacgccatgagcagcttctcctccggggtggccggcggcgcagtt
ggaggtgtctttaaccacgcggtgcctcccgcctccgcccatccgtttggagccagtttc
ggcagtggggctgcatgtcgcagcaccacgctgaacttaaccccgctgcagccggtggcc
agcaccccggcctcttcctttcaggccccgtcctctgcggagccgaggccgcccccactc
cctcctcacctgggccggccccctccggggcagcccaccctccatgcacccgcccaccct
aacgccaccttgcctcctccccctgcgctgctcccagctaactctgagcccgtgcttctg
cagaacctcgcatccctccctgctaaccaagctttcttacccacctcctctgctgcctct
ctgccgcctgctaacgcctctctgtccatcaagctcgcctccctcccgcacaaggtgtcc
cgcccctccttgacggtgcaccaccagcccctgcctgggctggccctggcccaggccgcg
cccgtgaacccacaggccagctccacagggccgcccgccgtgtgggtttcccttggcatg
ccgcctccgtatgccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
