Mycobacterium tuberculosis variant bovis BCG Mexico: BCGMEX_2509c
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Entry
BCGMEX_2509c CDS
T01727
Symbol
pdhA
Name
(GenBank) Pyruvate dehydrogenase E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mbm
Mycobacterium tuberculosis variant bovis BCG Mexico
Pathway
mbm00280
Valine, leucine and isoleucine degradation
mbm00640
Propanoate metabolism
mbm00785
Lipoic acid metabolism
mbm01100
Metabolic pathways
mbm01110
Biosynthesis of secondary metabolites
mbm01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mbm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
BCGMEX_2509c (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
BCGMEX_2509c (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BCGMEX_2509c (pdhA)
Enzymes [BR:
mbm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
BCGMEX_2509c (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
MCD
Motif
Other DBs
NCBI-ProteinID:
AET19783
LinkDB
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Position
complement(2754154..2755257)
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AA seq
367 aa
AA seq
DB search
MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE
FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW
RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH
EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY
AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL
QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR
AELARTD
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgggggagggttctcggaggccatctgggatgttgatgtctgtcgatcttgagccggtg
caactcgtcggcccggacggtacgccgacggccgaacgccgctaccaccgtgaccttcct
gaggaaacgctgcgttggctctacgagatgatggtggtcacccgcgagctggataccgaa
ttcgtcaatctgcagcgccagggggagctggcgttgtacacgccctgtcgcgggcaggaa
gccgcgcaggtgggtgcggcggcttgcctacgcaaaaccgactggttgttcccccaatac
cgagaattgggcgtctacctagtgcgtggcatcccgcctggacatgttggggtcgcgtgg
cgtggaacctggcacggcgggctgcaattcaccacgaagtgctgtgcaccgatgtcggtt
cccatcggcacccagaccttgcacgcggtgggcgcggcgatggccgcgcaacgcctggac
gaggactccgtgacggtggcctttctgggcgacggcgccaccagcgagggcgacgtacat
gaggcgctcaatttcgcggcggtgttcaccacaccgtgcgtgttctacgtgcagaacaac
cagtgggcaatctcgatgccggtatccaggcagaccgccgcaccatctatcgcgcacaag
gcgattggctacgggatgccaggcatccgggtggacggcaacgacgtgctggcatgctat
gcggtgatggccgaagctgccgctcgggctcgggccggcgacggtccaacgctgatcgag
gcggtcacttaccgtcttggtccgcacaccaccgccgatgatccaacccggtaccgcagc
caggaggaggtggaccgctgggcgacgctggacccgattccgcgctatcgcacttactta
caagatcagggcctgtggtcgcaacgcctcgaggaacaggtgacggctcgggcaaaacac
gtgcggtccgagctacgcgacgcggtctttgatgcgcctgacttcgacgtcgatgaggtg
ttcaccacggtgtacgccgaaatcacacccgggttgcaggcgcagcgcgaacagctgcgt
gccgaactggcgcggactgactga
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