Mycobacterium tuberculosis variant bovis AF2122/97: BQ2027_MB1136C
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Entry
BQ2027_MB1136C CDS
T00132
Name
(GenBank) 3-beta-hydroxysteroid dehydrogenase
KO
K16045
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mbo
Mycobacterium tuberculosis variant bovis AF2122/97
Pathway
mbo00984
Steroid degradation
mbo01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mbo00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
BQ2027_MB1136C
Enzymes [BR:
mbo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
BQ2027_MB1136C
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
BQ2027_MB1136C
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Gene cluster
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_10
NAD_binding_4
RmlD_sub_bind
NmrA
Polysacc_synt_2
KR
adh_short
Motif
Other DBs
NCBI-ProteinID:
SIT99736
Pasteur:
Mb1136c
UniProt:
A0A1R3XXD8
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All DBs
Position
complement(1234243..1235355)
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AA seq
370 aa
AA seq
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MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL
QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR
AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT
CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV
PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG
FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR
AEKTAATVKP
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atgcttcgccgcatgggtgatgcatcgctgacaaccgagctcggccgcgttctggtcacc
ggcggcgcgggcttcgtgggcgccaacctggtgaccaccttgctggaccgcgggcactgg
gtgcgttccttcgaccgcgcgccgtcgctgttgcctgcgcatccgcaactggaggtgctg
caaggggacatcaccgacgcggacgtctgcgccgcggccgtggacggcatcgacacgatc
ttccacaccgcagcgatcatcgagctgatgggcggcgcgtcggtcaccgacgagtaccgc
caacgtagctttgcggtcaacgtcggcggcaccgagaacctgctgcacgccggccagcgg
gccggggtgcagcggttcgtctacacgtcatccaacagtgtggtgatgggcggccagaac
atcgccggcggtgacgagacgctgccctataccgaccggttcaacgacctctacaccgag
accaaggtggttgccgagcgattcgtgttggcccagaacggtgtcgacggcatgctgacg
tgcgcgatccggcccagcggcatctggggaaacggcgatcagacgatgttccgcaagctg
ttcgaaagtgtgctcaagggccacgtcaaggtgctggtcgggcgcaagtcggcccggctg
gataactcttacgtgcacaacctgattcacggtttcatcttggccgctgcccatctggtg
ccggacggcacagcgcccgggcaggcttacttcatcaacgacgcagagccgatcaatatg
ttcgagttcgctcggccggtgctcgaggcgtgcgggcagcgctggccgaagatgcggatt
tccggccccgcggtccgctgggtaatgacggggtggcagcggctgcacttccggttcgga
ttccccgcgccgctgctcgagccgctggccgtcgaacgactgtacctggacaactacttt
tcgatcgctaaggcacgccgcgacctgggctatgagccgctgttcaccacccagcaggcg
ctgaccgaatgcctgccgtactacgtgagtctgtttgagcagatgaagaacgaggcccgg
gcggaaaaaacggccgccacagtcaagccgtag
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