Mycobacterium tuberculosis variant bovis AF2122/97: BQ2027_MB2697C
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Entry
BQ2027_MB2697C CDS
T00132
Symbol
hemE
Name
(GenBank) probable uroporphyrinogen decarboxylase heme (uroporphyrinogen iii decarboxylase) (uro-d) (upd)
KO
K01599
uroporphyrinogen decarboxylase [EC:
4.1.1.37
]
Organism
mbo
Mycobacterium tuberculosis variant bovis AF2122/97
Pathway
mbo00860
Porphyrin metabolism
mbo01100
Metabolic pathways
mbo01110
Biosynthesis of secondary metabolites
mbo01240
Biosynthesis of cofactors
Module
mbo_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mbo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
BQ2027_MB2697C (hemE)
Enzymes [BR:
mbo01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.37 uroporphyrinogen decarboxylase
BQ2027_MB2697C (hemE)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
URO-D
DUF6726
Motif
Other DBs
NCBI-ProteinID:
SIU01315
Pasteur:
Mb2697c
UniProt:
Q7TY47
A0A679LI84
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Position
complement(2954935..2956008)
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AA seq
357 aa
AA seq
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MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE
ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ
AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA
LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP
MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV
VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgagtacccgtcgcgaccttccgcagtcgccgtatctggccgccgtcaccggccgcaag
cccagccgggtgccggtgtggttcatgcggcaggccgggcgctcgttgcccgaataccgg
gcgctgcgcgagcggtacagcatgctggcggcctgtttcgaaccggacgtggcctgtgag
attaccctgcagccgatacgccgctacgacgtcgacgcggccatcctgttctccgacatc
gtggtgccgctacgggcggccggcgtggatttggacatcgtcgccgacgttgggccggtg
atcgcggacccggtgcgcaccgccgccgatgtcgccgccatgaaaccacttgatccacaa
gcgattcaaccggtattggtggcggcttcgttgttggtcgctgagcttggcgacgtgccg
ctgatcggtttcgccggcgcgccgttcacgctggcctcctacctcgtggagggcggaccg
agccgccatcacgcccacgtcaaggcgatgatgttggccgagccggcgagctggcacgcg
ctgatggccaagctgaccgacctcaccatcgcgtttctggtcggccaaatcgacgcgggg
gtggacgccatccaggtattcgactcctgggccggggcgctctcgccgatcgactaccgc
cagtacgtgttgccgcacagcgcccgggtgttcgctgcgctgggcgagcatggcgtgccg
atgacgcacttcggggttgggaccgccgaattgctgggcgcgatgtcggaggccgtgaca
gccggggagcggccaggccgaggggccgtcgtcggcgtggactggcggaccccgctgacc
gacgccgccgcccgggtggtgcccggcacggcgttgcagggcaacctcgatccggcggtg
gtcctggcgggctggccggcggtggaacgtgccgcacgtgccgttgtcgacgacggacgc
cgcgccgtcgacgccggtgcggccggccatatcttcaacctcggccacggggtgctgcca
gaaagcgatcccgcggtgctggccgacctggtctcgctcgtacactcgctatga
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