Mycobacterium tuberculosis variant bovis AF2122/97: BQ2027_MB3019C
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Entry
BQ2027_MB3019C CDS
T00132
Symbol
leuB
Name
(GenBank) probable 3-isopropylmalate dehydrogenase leub (beta-ipm dehydrogenase) (imdh) (3-ipm-dh)
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
mbo
Mycobacterium tuberculosis variant bovis AF2122/97
Pathway
mbo00290
Valine, leucine and isoleucine biosynthesis
mbo00660
C5-Branched dibasic acid metabolism
mbo01100
Metabolic pathways
mbo01110
Biosynthesis of secondary metabolites
mbo01210
2-Oxocarboxylic acid metabolism
mbo01230
Biosynthesis of amino acids
Module
mbo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mbo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
BQ2027_MB3019C (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BQ2027_MB3019C (leuB)
Enzymes [BR:
mbo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
BQ2027_MB3019C (leuB)
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Motif
Pfam:
Iso_dh
IFRD
Motif
Other DBs
NCBI-ProteinID:
SIU01643
Pasteur:
Mb3019c
UniProt:
P94929
A0A679LIA3
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Position
complement(3313486..3314496)
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AA seq
336 aa
AA seq
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MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN
VLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
NT seq
1011 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcgcgatcattgccggtgacgggatcgggcccgaggtaaccgccgaggcggtc
aaagtgctcgacgcggttgtgccgggcgtccagaaaaccagctatgacctgggtgcgcgg
cgctttcatgccaccggcgaggtgctgccggactcggtggtggccgagctgcgcaaccac
gacgcgatcctgctcggggcgatcggtgacccgtcggtgccaagcggcgtcttggagcgc
ggtctgttgctgcgactgcgcttcgagctggatcaccacatcaacctgcgtccggcccgg
ctgtatccgggggtggccagcccgctgtccggcaatcccggcatcgacttcgtggtggtg
cgcgagggcaccgagggaccctacaccggcaacggcggggcgattcgcgtcggcacgccc
aacgaggtggccaccgaagtcagcgtgaacaccgcgttcggtgtgcggcgtgtggttgcc
gacgcgttcgagcgggctcgacggcgtcgcaagcatctgacattggtgcacaaaaccaac
gtgttgaccctcgccgggggattgtggttgcggaccgtcgacgaggtcggcgaatgctac
ccggacgtcgaggtggcctaccagcacgtcgacgccgccaccatccacatgatcaccgac
ccgggtcgcttcgacgtgatcgtcaccgacaacctgttcggcgacatcatcaccgatctg
gccgcggcggtatgtggcggtatcggcttggcggccagtgggaatatcgacgcgacccgg
gccaacccgtcgatgttcgagccggtgcatggcagcgcgccggacatcgccggtcagggc
atcgccgacccgacggcggcgatcatgtcggtggcgttattgctgtcccaccttggcgaa
cacgacgcggctgcccgggtggaccgggccgtcgaggcccatttggccacgcgtggcagc
gaacggcttgccaccagcgatgtcggcgaacggattgccgccgcgctctag
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