KEGG   Mycobacterium tuberculosis variant bovis AF2122/97: BQ2027_MB3077C
Entry
BQ2027_MB3077C    CDS       T00132                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase (alpha chain) nrde (ribonucleotide reductase small subunit) (r1f protein)
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
mbo  Mycobacterium tuberculosis variant bovis AF2122/97
Pathway
mbo00230  Purine metabolism
mbo00240  Pyrimidine metabolism
mbo01100  Metabolic pathways
mbo01232  Nucleotide metabolism
Module
mbo_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
mbo_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mbo00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    BQ2027_MB3077C (nrdE)
   00240 Pyrimidine metabolism
    BQ2027_MB3077C (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mbo03400]
    BQ2027_MB3077C (nrdE)
Enzymes [BR:mbo01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     BQ2027_MB3077C (nrdE)
DNA repair and recombination proteins [BR:mbo03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    BQ2027_MB3077C (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-ProteinID: SIU01702
Pasteur: Mb3077c
UniProt: P0A5W9 A0A679LIH1
LinkDB
Position
complement(3373057..3375138)
AA seq 693 aa
MLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYS
RNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGD
TALAELLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRVEDNMESIGRSINSALQLS
KRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHA
HHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVP
FADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIDGK
ITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRA
LTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTV
LYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIP
TQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVY
YPAPYMTNDNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQI
YAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML
NT seq 2082 nt   +upstreamnt  +downstreamnt
atgctgaacctgtacgacgcggacggcaagatccagttcgacaaggatcgggaagcagcc
caccagtactttttgcagcatgtcaatcagaacacggtcttcttccataatcaggacgag
aagctcgactacctgatccgcgagaattactacgagcgtgaggttctcgaccagtactcg
cgcaacttcgtcaagacgctgctagaccgcgcctacgccaaaaagttccggtttccgacg
tttttgggtgcgttcaagtactacacctcctacacgctgaaaacctttgacgggaagcgc
tatctggagcgcttcgaggaccgcgtggtcatggtggcgctaacgttggccgccggcgat
accgcacttgccgagctgctggtcgacgagatcatcgacggccgcttccagcccgccaca
ccgacgtttttgaattctggcaagaagcagcgcggggagcccgtgagctgttttttgctt
cgcgtcgaagacaacatggagtcgatcggacggtcgatcaactccgcgctgcagctatcc
aagcgtggcgggggagtggcgttgctgctgaccaacattcgcgagcacggcgcgccgatc
aagaacatcgagaaccagtcctcgggcgtcatccccatcatgaagttgctggaggatgcg
ttctcctacgccaaccagctgggcgctcgtcaaggtgccggcgcggtgtacctgcacgcc
catcaccccgacatctaccgattcctggacaccaagcgtgagaacgccgacgagaagatc
cggatcaagacgctgagtctgggggtggtgatccccgacatcaccttcgagttggccaag
cgcaacgatgacatgtacctgttctcgccctacgatgtcgagcgggtctacggtgtgccg
ttcgctgacatctcggtcaccgagaagtactacgaaatggtcgatgacgcgcgcatccgc
aagaccaagatcaaggcacgggagttcttccagacgctggccgagctgcagttcgagtcc
ggctacccctatatcatgttcgaagacaccgtcaatcgcgctaatccaattgatggcaag
atcacgcacagcaacctgtgctcggagatcctgcaagtgtctacgccgtcattgttcaac
gaggacttgtcgtatgccaaagtgggcaaagacatttcgtgcaacctggggtcgctgaac
atcgccaagacgatggactcgccggacttcgcgcagacgatcgaggtggcgatccgcgcg
ttgaccgcggtgagcgaccaaacccatatcaagtcggtgccctcaatcgagcagggcaac
aacgactcccacgcgatcgggctaggacagatgaacctgcacggctacctggcccgggaa
cgcatcttctacggatccgacgaaggcatcgacttcaccaacatctacttctatacggtg
ctgtatcacgcgttgcgggcatccaaccgcatcgcgatcgaacgcggcacgcacttcaag
ggtttcgagcggtccaagtacgcgtccggggaattcttcgacaagtacaccgaccagatt
tgggagccgaagacccagaaggtacgccagctgttcgccgacgccggcatccgcatccca
acgcaggacgactggcgtcggctcaaggagtcggtgcaagcgcacggcatctacaaccag
aacctgcaggcggtgccgccgaccgggtcgatttcctacatcaaccattcgacgtcgtcg
attcacccgatcgtgtcgaaggtcgagatccgcaaggaaggcaagatcgggcgggtctac
tacccggcgccgtatatgaccaacgacaacctggagtactacgaagacgcctacgagatc
ggttacgagaagatcatcgacacctacgcggcggccacccagcatgtggatcaagggctt
tcgctgacgttgttcttcaaagacaccgccaccacccgcgacgtgaacaaggcgcagatt
tacgcctggcgcaaggggatcaagacgctgtactacatccggctgcggcagatggcgttg
gagggcaccgaggtcgagggttgcgtgtcctgcatgctgtag

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