Monosiga brevicollis: MONBRDRAFT_33840 Help Entry MONBRDRAFT_33840  CDS       T01042                                  Name (RefSeq) hypothetical protein   KO K22754   E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27] Organism mbr  Monosiga brevicollis Brite KEGG Orthology (KO) [BR:mbr00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:mbr04121]     MONBRDRAFT_33840 Enzymes [BR:mbr01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      MONBRDRAFT_33840 Ubiquitin system [BR:mbr04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    Other single Ring-finger type E3     MONBRDRAFT_33840 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ZnF_RZ-type NHL AAA_22 AAA AAA_5 nSTAND_NTPase5 mTOR_dom TsaE AAA_7 AAA_16 nSTAND3 Motif Other DBs NCBI-GeneID:  5894029 NCBI-ProteinID:  XP_001748831 JGI:  33840 UniProt:  A9V7V3 LinkDB All DBs AA seq 5844 aa AA seqDB search MVSSAIFRWSDVNIRDREQSYAPPIRVVRDGAQIAQTFSLKQHAEAEKSPSTVLFLELAV TEHGRLFCDIITLHTPRNLSLSLSLFLSLSLSLSFSLSLSLPQALSLSLIYFFFFFVLRH LAISLGAPFPPLLEVVISFYVLCPRELERKGVITCSQLSITADAAPTDWALDQAVGRLTS APAQVTLPQRTGSNPPPLGVQRQLSVLPGPGSDELPATSRLEFRHRDPSQALSLRRHGSH LSVASLVIPAGWHQDATAWQSTTPHTDLDFVTPWPAHLTVHLHTAAGDASFSALIDPGQP TSTHVWLSLDVARPNGVLPASSYPTLVDALTAVLKQAQATEPRQAVEARMLAILHALGPM LDTMRHQNIDNEDGFQHYVAACREALPDLTPAQHVIWVLCLLAQWAAVFKLQPSTTILAL WANCTLSASDTHELGAWAAQRNNSAWWSSGYEAVYGAACQGLMLLVDLDAASLAWSFRSL RAHALLQALARPLENALRRLSPRSLRCDLAPDLNRLASDMGGLRDAVTYKPGQSKLPQFF RDARNPDNLPRTLLVAHQIEALSQRLRPAAVQEIQRLLAISDDATRRTEAYRTLKWIVSV PKQIQTTPNALAKVEAQVQKADEQLNQLATVRQMTARVRGNYLNDVGVQRLSQRFNFQAD DEVLLKVPLEDKSKTRLRQLCKATVRKLQEGALADADAANEPTRLEDRFDPIDYRLTTIA GTGFSGFVDSHLENQRRDLIEAQNRRTRQQIDRLVARGRPVPDNLRVFELRARRVQLANP YGVALYKDDSILLTERNNNSIRLVNLLTGETECLNHGGHDVPLAAHRDGRLSDACFHRPS GICQLEDGSFLVADSANHCIRSISRSLSTVKTFAGQPGQAGGAEGAVSKAQFNQPSDLLV LDEKRILISDEANNSIRLLQLQKDKNWTVTTVAGSRTAGFADGRRGSTQLNQPRGMCFLN QRRTVVAIADAGNHCIRALNTSDWSLKLVAGVPGRAGRRYGKILESLFRTPSSVALDTDG DLLVADLENDRISAILMEERVVVPVVRSAREAGDAATQTGGNQDQFIDGSGLVARMSEPR TLHALPDGGVLLQFQKMLTDYVAALAQLRAANETAFRAMEGITTQLRSCATATDAAAHDL REQLFRSEVKHLGQDRAQRRQADVLEHWRCLLNTVPSLQLWASLLAEPLLQASDGRALAQ NNLLNFLGTYAWPKSSITSDFEGLAALQKAGFLTEAHLTRIFVSKNLRARQGATLLPGML PFLRLVLANVQPAASPQLAAAMVALVEAAQTARRQQDKADGEAERAAAAGGLATHVRRRL LQVLHWWSETHVQLKEDRDVTDGLLQLQLHQLCSEDHLPATLAAMPTILQDFEIAPHVLG RTMKAVVQNVHRCPDDELWEAIAALNALVEADRRLAHRVFLYGLIEAATAPLAHELQPLL DACRGQALDLAGQAWLASHVTFVARFLSWFHQEEADRFSLPEEHRLEPRMKAAWAQMTSC SGGLQDVVERAYLALQARTICPDALQALLRKRRDFSMALPGHSPTAYALLVQAQGDMEAY RRLLAQLGRVFEDLLPTDPSATTFEDIQATWRSMPLCVTAHRLRQPVAEAAGVPTEELAL QSFQATDDEGASQLLPTLLLKALPWLLSLREDALFLAVWHTFGQSVADLPDFVAHWQSLA QEVSVRAIHASRLYAWRQLWTEGSVRLLLRTGLRKRDAELEPSIEAAISPAPMLTKEDLD LDLDLDLVNDERIQTAPQLHADMQAALHLIELVKKRVTVQDLLKEMSPLLSEIGQREART WATLLHNASIDVAETLDEASLAALTVPAQRLLAVHPSVLKVEQRPIQLLQAHATLFAWLR LTFFSDSDFKASIEMALGKNESECPFELWVDGHVDDKMLARLETVRRQFYPFIYRRQDIL GHVDELLAILEDMETTDWNQTAVSLETVQGVLQPLSELVDPIGDAASSQLLKLLSPASEA CWRFAAAWPDVDPSLCVTYIVNVKGKKIAKQRSLAELEDFNASVLLRDGPGGTRQEHVDQ FIGQFHWAKLLHTTLLELQDMGHVNFMAYQVNLSLSLTADEVRLQYRRYRDMRDAWRTQL MQLRQARHAMATFRVSQLWTFLRELVEHRFSLQAAREVVGSWNVDLAHESEVVEEVALRV LGAWRTGNAAWAEPATSITLATNACVPVLAAPAAGAEKRSQASRKGPSAQQILVLLADAL HAGVADLPLPIRAFPREHYHMSDAHLDKERTEDVELPRLRVVCAASAEDAWLLSMGEFVA HGHMPEAQTLLLCGDDTPLDSVSTFLFRWCNRDATQGPGVHVLMAYECAQAKQAVIAQLI NERRFEASNPLLVVTGSVATHQLAALLSSAQSPKRVVDPLAIQHLLRLHADQETAGFKLL MGPQGAGSGKSHRIRQLARRSRRRYHYVAVHHHEALVETLVANLLAATSQTATPEPCVVH LDVDLHPSDAGYFQRALLTLASTRVLAAHQASFYWDYRNVEFIVELGNGAATRTMFIPRA LPGETLLFDPSTLQTSADELRDAMLPHEFLGPEDAPDEDAAFKLRYLVGILLILQDNSGQ EFPLRAAYAPPPADELHGRMASEVLLNAVPETRDGLSFHTLWAFVKIAYNSLKRLFEEGG LLERLKQDREGSKHAALIMLFVLNTAKEMSLRQDVLVSTSSSASIRFMPSHEAMAGLEQP ASLMSLRNTYTRGKDVDFEPHFTAVNSHSGFDFRFNRRLRLWTGGQSRRKGFDGIACFSL DPSTRPWTVIMAQPTKWTHVSSVEPGAEMQADDAGRAPQPLDDWRTQRSSTANNQVGGAR NGLTITSQDSNDEPALGQYLPLEPEPVDWLGALQHPSGRFRAVRHQQQWLIFEAIDGAFR PYAASTERGWFRAQYSLTDKDEDKFACNIDELRHLLPTATREETTQLTTEGDASSSQPST DAQAPFASLALRDETQPIIDILGWEKSSHDFLVFQNSSLVFSAQADVAAADGNQSTQGDR EGQVAGMEARSSSAMLLSLMPYMLRSLKLGLETVRLLESLDVLVPHSVSDLNTRLADALA FVTGVRNEEALADGTYVLTLDNVMKMVSVFTRMQAGLPVLLQGECGAGKTALLRFLARWL GAELVILDVHGGTTVDDIETTFAKAEHAAQEGARVLVFLDEFNACEHTGFIKTVFCERRL RDRFLHPGVRVLGALNPYRRRQRAAAVTPGLIFSLNREQTDTMSELVYRVNAVPDTLYEY VFDFGQLTSHQEASYIERMIEAMHLAKEPSCIHLLRVLISASQAYIRNVEGDSSAASLRD VRRCLHLTQWFLDHVTSGTDQASQQKISPLGVAFTLALAFTYWYRLNSEADREGYWQKLR DSGDFNTHALMEQRLDVLRKRGMFGRILRHIRNKFCANIQTDDDIAMNDALSENVFVTII ATLNTLPTFIVGKPGSSKTLALQLREFFPSTKWSDRALFVSLSLSLSLSLSLSLSLSLSL SLSLSLSLSLSLSLSLSLSLSLSLSLSLSLFFPFFRFRLHACLPAHFACLDGAFFQACRY QEHAKDALSVLVLDEVGLAEFSPDMPLKVLHGMLAEPRVPIVAVSNWALDAAKMNRALCL ARPHPSLESLEETGEHILQHGVHAPGQAALLKKLLRPLALAYHALLQRAENGKDRVFFGM RDFYSLLKLIKRKTGESVVRFKGNITSEFLNMCVCRNFGGNSKLLDVANKLFHQHCVGYA PASGPLHVGRLVLDNLSDPLARHLLLFTSYGSALDILTGSGLVDLTHSEILIGSQFSSDA DELKLVQQINRVRRAMKTGKLLPVSVCVCVYVRVCVCVCVCVCVCVCVCVCVCVCVCVCV CVCVCVCVCVCVCVCVCVCVCVCVCVCVCVYDALNQKYVVKQGKNGQVKRMLRLAIGSRS QLVEVQAGFKIIVIVEDSARNSLDLPFLNRFERQLLRPSDWTSRRYAVALDDIKSFLHAI QEECGLRLTGIFPSFQRDSVASALIQGAEYSQQPTHDECLQASQVAKAMLARCASPVAVQ FSPTLQQQFPRGVDSYFKAQASLQVLLKRHLQRRDAFEAARRRTCAAHRVQRQAAERAAA DNMACTVETSDAAPSEIASTEAARLVPTTTGMNETDTPATGAEPTPAPQSLLLVLTPSPA GDIPRLGDLQQLLPGTLLEHEQLSHFHSEDQLTSRLDRFFEGATRARQAAHKPQNEPRRV FLISCDALETRKEAINHTIFLCQARQRAADAAWRSALEAEDTAPDQAAVEDEAARRAEWS TESGRPLIVVVIHLPSSVKQRGRDFPLVFRGGWDTLYCDNLQHSSQQLGQLRALLELDAA TLIKTQQIDAVAILREHYHRVVVQTVVPAQVYATVYDRLREFNDLLKQPTFTDQLLKLVV GFLRRANQADARGIHLHVQWACSFQVSCLFESLQAALRDLVVDATSFAYALLEQDFGLHL LHQAFVHQNTAVVELWSELLERQIGLKMDVVAFGYKPQRQRTIAVENSGLNCFAREVLPR QQSLLALFFAPAQAMLQDSVAGEGGVETSEEPAAVQASDDAVGDPLAAYEARLALLLPSS LMQQLELAHLNVPPDAYMDSLLLQTFGRHEHHPDLEKWVTTEYRPDRLLAQGDCAIVETC VRDAMQSLRAQPRLIDAYRHSLQLVVDASAMESLLLENQTPQATALTVCMHLRKGQSTQD EVAAIEAQSLRLVRDLTLLDDTDFVGSNGWALLTPLLAAHCVELVYSCLPALVNHVPDAV QLLTDLARLEWPSECLVQQTLQDQLRVALGAIYTLYGWLKTTDDTPYYRLLACLEGCTQE AGLIALQLFVLDCARTEQLDTEKPLQAADVGVVLAEPALPDTNGQLPIQAATFEQAKCAL RRAMEHMMRRIPASPEFPDPVQLILTRPEGADFFVKVMVSAHGPSALLDALSLGEAVTPF LAPIRSLAHVYGASARGSRSSQNHIDVFRCLESQAYSEILIAVHRAHHTGSTDLLDNIFT AKVFRDPAKHLPTWVGALLHVVHSCEDNIKSTVVKTWLERTYKPLLGSTQQEILDWALNG FQLAGKTQHCRTPNTLPFLRNMNTQLCALVAILAVEQPDSWIGQLVWHPESTQKHFLPGM PGNDFSMVLNESPWVGWYKCPNGHLYCVDNCTMPMERSTCPDCRAVIGGESHVSVRGVVR LTDEEVQGMRIAPNRGYSDSFCHSTDGKLGRPISNFSQQFIHLIVHAALRLAMTLRPTPG WRFLTMAASQRGTLSRDEMATRFHKIAIQATAGSSFKLEHILVLTVTILTDMLKTKIAPA FVTHESRDLYELHLQRTFIDPRLADRSKIHGMTAHLKDRAKTELLEKIWSEFCKEADSRA SEEGRVKLSALLWSPRPKADFDTFVATFGAIGSNQQNFPVLAACLRVQNRLQLVRHLTPI LGWHAILFEVFANSSLSREDAAAIRNCDVAFNATLPMLSPNIYECTPNPFLTADGRVNLK GTGDEENPMTPEVAVIFSLPVLLVGQETDARGLCTVQLCRMLVQAHNDVMTALRVAQLKR TAGGDHDTDMGNVHTALEAKTEGPEVPGAAQVVVSHKTSAAQLDALLLNFSIESTAQRMV SIAAQRTIECVNLETPITFDFGLVERWIEQSLLSGKRGVQLDLREYRYAGDVEAVGHLAA LRQRIPQVQLSASVKQELLRELDVQSRLRILRRLLEDAIALLATLGGQGSELLGLDPTVQ LRDYMLTSMNVSATEWNKVANECLDSQVQLQHLQSLLLLLETESVDGPLEQVHEAYRESL DEELAQAVRALLFKVDLSVISSVLHDLLTNQLKDDQWPANGSLKEYLGYCTEEDLDELPW FRELPDTLELRHAVALYELMSAST NT seq 17535 nt NT seq  +upstreamnt  +downstreamnt atggtttcttctgctatttttagatggagcgatgtcaacatcagagatagagagcagagt tatgctcctcctatcagggttgtcagagatggcgcccagatcgcccagacttttagcttg aaacagcatgcagaagcagagaagtctcccagcaccgtgcttttcttagagctggccgtc acagagcacggacgcctgttttgtgacatcataactctacacacacccagaaacctctct ctctctctctctctctttctctctctctctctctctctctctttctctctctctctctct ctccctcaagctctctctctctctctcatttattttttttttttcttcgtccttcgacac ttggcaatctcactgggtgcgcccttcccgccccttttagaagtcgtcatctcgttctac gtgctgtgcccccgtgagctcgaacgcaagggtgtcatcacctgtagccagctgtcgata acggcagatgctgctccgactgactgggcccttgatcaagctgtcggccgcctcacctcg gccccagcccaggtgacgttgccccagcgcacagggtcaaatccacccccactgggagta cagcgccagctgtccgtcctgcctggccccggctcagatgagcttccggccacaagtcgg cttgagttccgccatcgagatccctctcaggctctctcactgcgccgacatggctcgcat ctcagtgtcgcaagcctcgtaattccagctggctggcaccaagatgccacggcatggcaa tccaccacgccccacacagatctggactttgtcacgccctggcctgcccacctgacggtg catcttcacactgctgctggtgatgccagcttctcggccctcattgatccaggacaaccc acctcgactcatgtttggttgagcctggatgttgctcgccccaacggcgtgctgcccgcc tcaagctatccgaccctggtcgatgctctcaccgccgttttgaagcaggcccaggccact gaaccgcgtcaagccgtagaagcgcgcatgttggccatcttacatgccctaggccccatg cttgacaccatgcggcatcaaaacattgacaacgaggatggttttcagcactacgtggct gcctgtcgggaggccctgccggaccttaccccggcccagcacgtgatctgggtcctctgc ttacttgcccaatgggctgcagtgttcaagctccagccctcaaccacgattctggcactc tgggccaactgcacactcagtgccagcgacacccacgagctcggtgcttgggctgcccag cgcaacaacagcgcgtggtggtccagtggctatgaagccgtttatggagctgcatgtcaa ggcctcatgctactggtggaccttgacgcagccagcctggcttggagctttcgctctttg cgggcccatgccctattgcaagcacttgcccgccctctagaaaacgcactgcgccgcttg agcccccgtagcttgcgctgtgaccttgccccggacctgaaccgcttggccagcgacatg ggaggcttgcgagatgcggtcacatacaaacccggccaatccaagttgcctcagttcttt cgcgatgcccgcaatcccgacaatctaccacgtactctcttggtcgcgcaccagatcgag gcactcagtcagcgcctgcgccccgcggctgtgcaagagattcagcgcctgctggccatt tctgatgatgccactcggcgaactgaagcctacagaacactcaagtggattgtcagcgtt cccaagcagatccagaccaccccaaatgccctggccaaggttgaagcgcaggtccaaaag gccgatgaacaactgaatcaactcgcgacggtgcgccaaatgacggcacgcgtccgtggc aactatctcaacgacgttggtgtgcagcgattgagccagcgcttcaattttcaggccgac gacgaagttctgctcaaggtccctttagaggacaaaagcaagacgcgtttgcgccagttg tgcaaagccaccgtccgcaagctgcaagaaggcgcgctggccgatgcagacgcggccaac gaacccactcgcctcgaggatcgttttgatcccatcgactatcgtctcacaaccattgcg ggcactggcttttcgggctttgtggactcgcacttggagaaccagcgccgggacctaata gaagcccaaaacaggcgcacgcgacaacagattgaccggcttgtggcgcgcggtcggccc gtgcccgacaatttgcgtgtttttgaacttcgtgctcgccgcgttcagctggccaacccc tatggcgtggctttgtacaaagatgacagcattcttctgacggagcgaaacaacaacagc attcggctcgtcaacctgctaactggcgaaacagagtgtctcaaccatgggggccatgat gtacccttggccgcccatcgggacggccgtcttagtgacgcttgctttcatcgcccatcg gggatttgccagctggaggatggcagctttttggtcgccgactcggcaaaccactgcatt cgcagtatttcccgcagtctgagcaccgtcaagacctttgccggccagcccggtcaagct ggtggcgctgagggagcagtttccaaggcgcaattcaatcagcccagtgacctgttggtt ttggacgagaagcgcatcttaatctccgatgaggccaacaacagcattcgactgttgcag ttgcagaaggacaagaactggaccgtgaccacggtggcgggcagtcgcaccgctggcttt gccgacggccgacgcggatccacccagctgaatcagccccgaggcatgtgttttctgaac cagcgtcgcacagtcgtggccattgccgatgccggcaaccactgcattcgggccctcaac acctcagattggagcttgaagcttgttgctggtgtgccagggcgggcgggccgccgatat ggcaagattcttgagtcacttttccgcaccccatcgagcgtggctctcgacacggacgga gatttgctggttgcagatctcgagaatgatcgcatctccgccatcctcatggaggagcgc gtggttgtgccggtcgtgcgaagcgcccgtgaggctggggacgctgcaactcagaccgga ggcaatcaagatcagttcattgatggctcgggcctggtggcacgcatgagcgagccccgc accctgcatgcgctccccgacggtggcgtactgctacaatttcagaagatgctgactgac tacgtggcggccctcgcgcagcttcgtgctgcaaacgaaacagcctttcgagcaatggaa ggcatcaccacgcagttgcgcagctgcgccactgccaccgatgccgctgcgcatgatctg cgtgagcagctctttcgctctgaggtcaagcacctaggacaagaccgtgctcaacgtcgg caggccgatgttctggagcattggcgctgtctcctcaacaccgtgccttcgctgcagctc tgggcttcgcttctggccgagcctcttttgcaggccagtgacggccgtgcccttgctcag aacaatcttctcaactttcttggcacctacgcttggccaaaaagctccatcacctctgac tttgagggcctggccgctttgcaaaaggcaggcttcctgactgaggcacacctgacgcgg atttttgtttccaagaatctgcgggctcgccagggcgccactttattgcccggcatgctg ccatttctgcgccttgtgctggctaatgttcaacctgcagctagtccccagcttgcggca gccatggtggcgcttgtcgaagcagctcaaactgcacgccgacagcaggataaggccgat ggcgaggctgaacgtgctgctgctgcaggcggtcttgcgacgcatgtgcgccgccgattg ctacaagtgttgcattggtggtcggaaacccacgttcaactcaaggaggaccgcgacgtc accgatggcctcctacagctacaactgcaccagctgtgcagcgaggatcatctgcccgct acccttgctgccatgcccacaattttgcaagactttgaaattgcaccacacgtgctcggc cgcaccatgaaggctgtcgttcaaaatgtccaccggtgtcccgacgacgagctgtgggaa gctattgcagctctcaatgcgttggtggaagcggatcgccggcttgctcaccgcgtgttc ctgtacggcctgatcgaggccgccaccgcgcctttggcccatgagctacaaccccttttg gatgcctgtcgcggccaagctctcgacttagccggacaagcctggctagcaagccacgtt accttcgtggcccgctttcttagttggttccatcaggaagaggccgatcgcttttcattg cctgaagagcaccgactcgaacctcgcatgaaggcggcgtgggcacaaatgacatcctgc agcgggggcttgcaagacgtcgtcgaacgggcctatcttgcccttcaggcgcgcacgatt tgtccggatgccttgcaagctttgctgcgcaagcgccgtgacttctcaatggctctgcca ggccactctccgaccgcatatgcccttctcgttcaagcccaaggagatatggaggcatac cgtcggttgcttgctcagttgggccgcgtgtttgaagatctgttacccacagacccctcc gccacgacctttgaggacatccaggccacctggcgctcgatgccgctgtgcgtcaccgcg caccgcttacgccagcccgttgctgaagctgccggtgtacccaccgaggagctggcgctt cagagctttcaggcgacggacgatgagggcgcctctcagctgctcccaacgcttcttctg aaggcccttccgtggctgctttccctgcgcgaggatgcgctgttcctggcagtatggcac acgtttggccaatcagtcgctgatttgccggattttgtggcgcactggcagagtttggcg caggaggtttcggttcgagctattcatgcatctcgtctttatgcttggcgccagttgtgg accgagggcagtgtgcgcctgctgctgcgtactggcttgcggaaacgtgacgctgaactt gagccaagcattgaggcggcgatctcgccagcaccgatgctgaccaaagaagatttggac ttggacttggacttggacttggtgaatgatgaacgcatacaaacagccccgcagctgcac gcagacatgcaggcagctcttcatctcattgagcttgtgaagaagcgagtgactgtgcaa gacctgctcaaggaaatgtcgcctcttttgagtgagattggccagcgcgaagcccgcact tgggccacgcttctgcacaacgcgagcatcgatgtggccgaaacgttagatgaggcctct ttggctgccctgacagtgccagctcagcgcctgctggccgtgcaccccagtgtgctaaaa gtggagcagcgcccgattcagttgttgcaggcccatgccaccctctttgcgtggttgcgc ctgacctttttctcggacagcgacttcaaggccagcattgaaatggccctcggtaagaac gaaagcgagtgcccctttgagctctgggttgatggccacgtggacgacaagatgttggcc cgcctggagacagtgcgtcgccaattctatccctttatatatcggcgacaagatattctt ggccacgtcgatgagttactggcgattcttgaggacatggagaccacagactggaaccag actgcggtcagcctggagaccgttcagggtgtattgcagcctctgagtgagctggtcgac cccattggtgatgcggcctctagccaattactcaaactgctgtccccagccagtgaggca tgctggcgttttgccgcagcttggcccgacgttgaccctagcctgtgtgtaacctacatt gtcaacgtcaagggaaagaagattgccaaacagcgttcattggcagagcttgaagatttc aatgccagcgtcttgctgcgtgatggacccggcggtacacgacaggaacacgtggaccag tttattggccagtttcactgggccaagcttctgcataccaccctactggagcttcaagac atgggtcacgtcaattttatggcataccaggtgaacctgtctctgagtttgactgcagac gaagtgcggctgcagtatcggcgctaccgcgacatgcgcgacgcctggcgcacgcagctt atgcagctccgccaggcgcgccacgcaatggccacctttcgcgtgagccagctttggact tttttgcgagagcttgtagaacaccgcttcagcctgcaagcggctcgtgaagtggttggc tcgtggaacgtggatctggcacatgagtctgaagttgttgaggaagtggccttgcgggta cttggagcctggcgcactggtaatgccgcctgggccgaaccagccacctcgatcaccctg gccacgaatgcttgtgtaccagtccttgctgcccctgctgccggcgcggagaagcgctcg caagcttcgcgcaagggaccgtcggcgcagcaaatccttgttctccttgccgacgctttg catgcaggcgtggctgatttaccgctgccgatccgtgcgtttcctcgagagcactatcac atgtccgatgcccatctggataaggagcggaccgaagacgtggagcttcctcggttgcgc gtcgtctgcgctgctagtgctgaggatgcctggcttctcagcatgggagaatttgtggcc cacggccacatgcccgaagcgcaaactttgcttctctgcggtgatgatacaccgctggac agcgtttccaccttccttttccgctggtgcaatagagacgcgacccagggacccggtgtc catgtacttatggcctacgaatgtgcgcaagccaaacaggcagtcattgcacaactcatc aatgagcggcgctttgaggccagtaatcctcttctggtcgtaacaggtagcgttgctaca catcaactcgctgccctgcttagctccgcacagtcacccaaacgggtggttgacccattg gccattcaacatctgctccgtttacatgcggaccaagaaacagctggcttcaagttgctg atggggcctcagggagctggtagcggcaagtcgcaccgcattcgacaattagcgcgacgt tcgcgtcgacgctatcactacgtggctgttcaccaccacgaggcactggtcgagaccttg gtggcaaacctgctggccgccactagccagaccgccacaccagaaccgtgtgtggtacat ttggacgtggaccttcatcccagcgatgcgggctactttcaacgcgcactgctgacgctg gcgagcactcgcgtgttggccgcccaccaggccagcttctattgggactaccgcaacgtg gagtttatcgtagagttgggaaatggggcagccacccgcaccatgttcataccccgagcg ctacctggcgagacattgctctttgatccgtcgacgctccaaacatcagctgacgagctg cgcgatgccatgttgccccatgaattcttgggtcccgaagatgcgcctgatgaggatgct gccttcaagcttcgatacctagtgggcattttgctcattttgcaggacaacagcgggcag gagtttcccctccgtgcggcttatgcgccacccccagccgatgaattacatggccgcatg gcctcggaagtcctgctgaatgcggtgcccgaaacgcgggatggtctcagctttcacacg ctctgggcctttgtgaaaatcgcctacaattccctgaaacgcctcttcgaggagggtggc ttgctagagcgactgaagcaagaccgtgaaggctcgaagcatgccgcacttatcatgctc tttgttctcaataccgccaaggaaatgtccttgcgtcaagatgttctcgttagcacctcc tcttctgcgagcattcggtttatgccaagccacgaggccatggctggtcttgagcagccc gctagcctgatgagtttgcgcaacacctatacacgtggaaaagacgtggatttcgaacct cactttacggcagtcaacagtcattcgggctttgatttccgtttcaatcgtcgtctgcgt ttgtggacaggtggccagtctcggcgcaagggctttgatggtatcgcctgcttctcattg gatcccagcactcggccgtggacggtgattatggcgcaacctacaaaatggacgcacgtg tcctctgttgaacctggtgcagagatgcaggccgacgatgcagggcgcgccccgcagcct ctagacgactggcgtacgcagcgctcttccacagccaacaaccaggttggcggcgcaaga aacggactgaccatcacttcccaagactccaacgatgagccagcacttgggcagtacctt ccactcgagcccgaacccgtggattggctgggtgcgcttcagcatccaagcggccgcttt cgagccgtccgtcaccaacaacaatggcttatctttgaggccattgacggtgcgtttcgc ccatatgctgccagcacggaaaggggctggttccgcgctcagtactcgttgaccgacaag gatgaggacaagtttgcctgcaacattgatgaactgcgacatcttctgcccactgcgaca cgtgaagaaactacgcagctaaccacagagggggatgcgtcatcatctcaacccagtacc gacgctcaggcacccttcgcctcccttgcgctgcgtgacgaaacccaacccatcattgat atcctgggctgggagaagtcaagtcatgactttttggtgtttcagaactcaagcctggta ttttcagcccaggccgatgtggcagccgcagatggtaaccagagcactcaaggagaccga gaggggcaggtggctggtatggaggcccggtcatcatcggccatgctattgagcctcatg ccttacatgctgcgctctctcaagcttggtctggaaactgtgcgtctgcttgagagcttg gatgtgctcgttcctcactctgtttcagacttgaacacgcggctggcagatgcccttgca ttcgtgacgggcgtgcgcaacgaggaagctctagcagatggcacctacgtgctaaccttg gacaatgtcatgaagatggtctccgtctttacgcgcatgcaggctgggctacctgtgttg ctgcagggcgagtgcggtgccggcaagacagcactcttgcgcttcttagcccgttggctg ggagccgaacttgtgatcctagacgtgcatggagggaccacagtagacgacattgagacc acttttgccaaagcagaacacgctgcgcaggaaggtgcgcgcgtccttgtctttttggac gaatttaacgcctgcgagcacacgggattcatcaagactgttttctgcgagcgccgcctt cgggaccgctttcttcatccgggcgttcgggttctcggcgccctcaacccttatcggcgc cgtcagcgggcggcagctgttacacccggccttatcttcagtctcaaccgtgagcagacc gataccatgagcgagctcgtgtaccgcgtcaacgctgtcccagacacgctttatgagtat gtgtttgactttgggcagctaacaagccatcaagaggcatcttacattgagcgcatgatt gaagccatgcaccttgcgaaggagccatcgtgcatacatcttttgcgtgtgctgatctct gcgtcgcaagcttacattcgcaatgtggagggcgactcaagcgcggccagtctgcgcgat gtgcgtcgttgcctgcacctgacccaatggttcttggatcacgtgaccagcggcaccgat caagcctcccagcaaaagatcagcccgctgggcgtagcctttacattagcactggctttt acgtattggtatcggctcaattcagaggctgatcgtgaaggatactggcagaagcttcgc gattcgggtgacttcaacacccacgctttgatggagcaacgcctagacgtgctgcgcaag cgaggcatgtttggtcgaattcttcgacacattcgcaacaagttctgtgctaatatccag acggatgatgacattgccatgaacgacgcactctctgagaacgtctttgtcaccatcatc gcaactctgaacacgctgcccacatttattgtgggcaagccaggcagctccaaaacgttg gctttgcagctgcgggaattctttcccagtaccaagtggtcagaccgtgctttgtttgtt tctctctctctctctctctctctctctctctctctctctctctctctctctctctctctc tctctctctctctctctctctctctctctctctctctctctctctctctctctctctctc tctctctctctctctctctctctctctctcttctttccctttttccggttccgtctgcat gcgtgtctgcctgctcactttgcatgcctcgatggcgcattctttcaggcctgccgatac caagaacacgccaaggatgctctcagtgtcttggtacttgatgaggttggcctcgctgag tttagccctgacatgcccctcaaagtgctgcatggcatgctggcagagccccgggtcccc attgttgctgtttccaattgggctttggatgcagccaagatgaaccgcgctttgtgttta gcccgccctcatccttcgcttgaatcgctggaagagaccggcgagcacattctgcaacat ggcgttcacgcgccaggccaggcggccttgctcaagaagctgctgcggccattggctctg gcttaccacgcgctactgcaacgtgcggagaatggcaaagatcgcgtttttttcggcatg cgcgatttctattcattgctcaagctcatcaagcgcaaaacgggcgagtccgttgtcagg ttcaagggcaacattactagcgaatttctcaacatgtgcgtctgccgcaatttcggaggc aacagcaagcttttggatgtagccaataagctcttccatcagcattgcgtcggctacgcc cctgcctcaggcccactgcacgtggggcggctggtgctggacaacttgagcgacccactt gctcgccatctcttgctcttcacttcgtacggcagcgccctcgacattttgacgggctca gggctcgttgatttgacccacagcgaaattctcatcggctcacagtttagcagcgacgct gatgagctcaagctggtgcagcagatcaatcgcgtgcggcgtgccatgaagacgggcaag cttctccctgtgagtgtgtgtgtgtgtgtgtatgtgcgtgtgtgtgtgtgtgtgtgtgtg tgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtg tgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtg tgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgacgcgttgaaccaaaagtatgtcgtc aagcagggcaaaaatggccaggtcaagcgcatgctgcgcctggcgattggctcgcgttcg cagctggtcgaggtgcaagccgggttcaaaattattgtgatcgtggaggacagtgcccgc aattcgctagacttgccatttttgaatcgttttgagcgtcaactactccgccccagtgac tggacctcccgccgctacgccgtggctttggatgacatcaaatctttccttcatgcaatc caagaagaatgtggcctgcgtctcacgggcatctttccttcattccaacgcgatagtgtg gccagtgcgctcatccaaggcgcagaatactcccagcaacccacgcatgatgagtgccta caagcgtcccaggttgccaaggctatgttggctcggtgcgcttcgccagttgccgtccag ttctcacccacccttcagcaacagtttccccgtggcgtggactcttatttcaaagcccaa gcaagcctgcaggtcctgctgaaacgtcatttgcaacggcgagacgcttttgaggccgct cgtcgtcgcacctgcgccgcacatcgagtccagcgtcaggcggccgaacgagccgccgcg gacaatatggcatgcactgtggaaacatcggacgctgcaccgagtgaaatcgcgtcgaca gaggcagcacggctcgtccccacgactacagggatgaacgagactgatacccctgctacc ggcgctgaacccacgccagcaccgcagtcactcctgctcgtgttgacgccgtcaccggcc ggggacataccgcgtcttggcgatctgcaacagctgcttcccggcacattgctagagcac gagcagctctcacactttcatagcgaggatcagctgaccagccgacttgaccgcttcttt gaaggcgctacacgtgctcgacaagcggcgcacaagccccaaaacgagccgcgccgggtt ttcctcatctcgtgcgatgctcttgagacgcgcaaagaagccattaatcacacaattttc ctctgccaggcccgtcagcgtgcagcagatgcagcttggcgctctgcgcttgaggcagag gatactgcacctgaccaagcagctgttgaagacgaagcagcgcgccgtgctgaatggtcc acagagtctggccgaccactcattgtggttgtgatacatttgccttcttctgtgaagcaa cgtggtcgcgatttcccgctcgtctttcgtggtggctgggacaccctgtactgtgacaac ctgcagcactcgtcacagcagctgggccagctgcgcgcactcctggagctggatgccgcc acgctcatcaagacacaacagatcgacgcggtcgccatccttcgcgagcactaccatcga gtcgtggtacagacagtggtcccagcacaggtttacgccaccgtgtatgaccggttgcgt gagttcaatgacttgctcaagcagccgacctttactgatcagcttctaaagttggtcgtg ggattcctgcgtcgggccaatcaggctgacgcgcgaggcattcacttgcacgtgcagtgg gcttgctcgtttcaagtgagttgcctctttgaatcgctccaagcggcgttgcgtgatctc gtggtcgacgcaacatccttcgcttacgctctgctggagcaagattttggcctgcatctc ttgcaccaagcctttgttcaccaaaacaccgccgtggttgagctttggagcgaacttttg gagcgacagattgggttgaagatggatgtggttgcctttggctacaagccccagcgccag cgcaccattgccgtcgaaaattctggcctgaattgctttgctcgagaggttcttccccgc caacaaagtttgctggcgctcttcttcgcgccagcccaggccatgctgcaagactcagtg gctggtgaaggtggagtggaaacgtccgaagagccggcagctgttcaagcaagtgatgat gctgttggtgaccctcttgctgcatatgaagcacggttggctttgctcctccccagctca ctgatgcagcagctcgaactggcccatctgaatgtgccgcctgatgcctacatggactca ctattgctccaaacttttggccgacatgagcaccaccccgaccttgaaaagtgggttacg accgaataccggccagaccgattgctggctcaaggcgattgtgccattgttgagacctgt gtgcgcgatgccatgcagagtctgcgagcacagccccgactaatcgatgcctatcggcat tctcttcagctcgtcgttgatgcaagtgccatggaaagtcttttgttggagaatcaaact ccacaagccacggccttgaccgtctgcatgcacttgcgaaaaggacagagcactcaggat gaggttgctgctattgaagctcaatctctgcgcctcgtacgtgatcttactcttttggat gataccgactttgtcggaagcaatggttgggccttgctgacgcccctgctggctgcgcat tgcgtggagcttgtctactcgtgcttgccggccttggtgaaccatgtgccggatgctgtg caattgctgacagacctggctcgcctagagtggccctcagagtgtctggtccagcagacg ctgcaggatcagttgcgtgtggctttgggcgccatttacacgctgtatgggtggctcaag acaacggatgacacgccttactacaggctgctggcatgccttgaggggtgcacgcaggaa gcaggactcattgccttgcaactttttgtacttgactgcgcacgcaccgagcaactagac acggagaagcccttgcaagcagctgacgttggcgtggttttggccgagccagcgctgcct gacacaaacggccaactgccaattcaagctgccacctttgaacaggccaaatgtgccctt cgccgcgccatggagcacatgatgcgccgaattccagccagtccagagttcccagaccct gtgcagttgattctgacaaggcctgaaggggctgacttctttgtaaaagttatggtttcc gcgcatggccccagtgctctacttgacgccctgtcgttgggtgaggccgtgaccccattt ttggctcccattcgaagcctggcacacgtttacggagcaagcgcgcgtgggtcgcgctcc tcgcagaaccacattgacgtcttccgctgcctagagagccaagcatacagcgaaatactg atagcggtgcaccgggctcaccacactggcagcactgatttgctggacaatattttcacc gccaaggtttttcgcgaccccgccaagcacctcccgacttgggtcggggcgcttctgcac gttgtgcattcttgtgaggacaacatcaagtcaacagttgtcaagacatggcttgagcgc acctataaacccttgctcggctcgacacaacaagaaatcctagattgggccttgaatggc tttcaattggcagggaaaacccagcattgccgtacacccaacacgttgccgttcttgcgc aatatgaatacccagttgtgtgccttggtggctatattggctgtggagcaacccgacagc tggattgggcagttggtctggcatccagagagcacccagaaacactttttgccaggcatg ccgggcaacgacttctcgatggtgttgaacgaatcgccctgggtgggctggtataagtgt ccaaacggccacttgtactgcgtcgacaactgcactatgcccatggagcgctcaacatgc ccagattgtcgtgctgtgattggcggcgaatcgcacgtatccgtgaggggtgtcgtgcgc ctcaccgatgaggaggttcaaggcatgcgcatcgcgcccaaccggggctattccgacagc ttttgtcactctacggatgggaaacttggacgccccattagcaacttttcgcagcagttc atccacttgattgtgcatgccgcacttcgacttgcaatgacactgcgccccacaccaggg tggcgctttttgaccatggcagcaagtcaaaggggcacgctaagtcgtgatgaaatggcc actcgcttccataaaattgccattcaagccacggctgggtcgtctttcaagctagagcat attttggtccttacggtcaccatcttgaccgatatgctgaagacaaagattgcacccgcc tttgtcacacacgagtcgcgcgacctgtacgaattgcacctgcaacgcaccttcatcgac ccacgactcgcggatcgttccaagatacatggcatgacggcacacctcaaggatcgggct aaaactgaactgctggagaaaatttggtctgagttttgcaaggaagcggacagtcgagcc agtgaggagggccgcgtcaagctctcggcgctcctgtggtcgccgcgacccaaggccgat tttgacacgttcgtggccacctttggggccattggctccaatcagcaaaattttcccgtg ttggcggcttgcttacgcgtccagaatcgtttgcagcttgtgcgccacttgacgcctatc ctaggatggcatgccatcttgtttgaggtgtttgccaatagcagcctcagccgcgaagac gcagcggccatccgcaactgcgacgtggcatttaatgcgacgttgcccatgctttcgccc aatatctatgaatgcacgcccaacccctttctcaccgcagacggtcgcgtgaatctcaag ggcacgggcgatgaggaaaaccccatgactcccgaggtggcagtcattttctccctgcca gttttgttggtgggccaggaaactgacgcccgaggcctctgtaccgtgcaactctgtcgc atgctggtccaagcccataacgatgtcatgacagccctgcgcgtggcgcagctcaagcgc acagctggcggggatcacgatacggacatgggcaacgtccacacggccttggaggcgaag acggaagggcctgaagtgcctggcgccgcgcaagtggttgtgtcacacaaaacgtctgcc gcgcaactggatgccctgctgcttaactttagcattgaatcgactgctcagcgtatggtc tcgattgctgctcagcgcactattgagtgcgtgaaccttgaaacgccaatcacctttgat tttggccttgtcgagcgctggattgagcaatccctgctatcggggaagcgcggtgtgcag ctggatctgcgagagtatcgctatgcgggagatgtcgaggctgtgggccatttggcggca ctgcgccagcgcatacctcaggtgcagctttctgcctcagtgaagcaagaattgttgcgt gagctagacgtgcaaagtcgccttcgcatcctccgacgccttttggaggatgccatagct cttttggcaaccctgggaggacaaggaagcgagctgctgggccttgatcccaccgtccag ctgcgtgactacatgctgaccagcatgaatgtgagcgcgactgaatggaataaggtggca aatgagtgcctggatagtcaggtgcagttgcaacacttgcagtctctcttgctgcttttg gaaacagaaagcgtcgatgggcccttggagcaagtgcacgaggcctatcgagagagcctg gatgaggagttggcacaggccgtgcgtgcgctcttgttcaaggtcgatctgagcgttatt tcgtcggttttgcacgatttgttaacaaatcagctcaaggacgatcagtggccggccaat ggatcgctgaaggagtacctcggctactgcactgaagaagatctggacgagctaccctgg tttcgagagctgcccgacactctggagctacgccacgcggttgcgctgtacgagctcatg agcgcctcgacgtga

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