Mycolicibacterium brumae: L2Z93_001054
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Entry
L2Z93_001054 CDS
T08531
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
mbrm
Mycolicibacterium brumae
Pathway
mbrm00280
Valine, leucine and isoleucine degradation
mbrm00640
Propanoate metabolism
mbrm00785
Lipoic acid metabolism
mbrm01100
Metabolic pathways
mbrm01110
Biosynthesis of secondary metabolites
mbrm01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mbrm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
L2Z93_001054
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
L2Z93_001054
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
L2Z93_001054
Enzymes [BR:
mbrm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
L2Z93_001054
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Motif
Pfam:
E1_dh
Transketolase_C
Transket_pyr
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
UWW08013
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Position
complement(1045837..1047969)
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AA seq
710 aa
AA seq
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MAEPIDDYFVAALRAHPGSAAGEPGLSVKEALAVFDAQIGSRHLDLAARALRARGRGYYT
IGSAGHESNAVVAAALRADDPALLHYRSGGFFLARAAQRDSERDALRDVLLGMVAATDEP
IAGGRHKVWGRHDLAVIPQTSTIASHLPRAFGMAFTLAAAQRSADCPWPADAVVACSFGD
ASANHSTAVGAINAARNAAFRGLPVPLLLVCEDNGIGISTRTPAGWIASSYANLPGLAYF
EADGADVAGAAAAATAAADWVRGRRSPAFLHLRTVRLMGHAGSDVETGYRTTAEISADYP
RDPVLATARWLIEHGGLAPEEVLGLYEDKREVVAALADEVCELPQLDSAEAVLTPLTTTA
QRARDVSSATRSTGDSGLTLAQSINAALVDVLETHSGATLFGEDVARKGGVYGVTRGLQK
RFGRSRVFDTILDEQTILGLALGAGLNGMLPIPEIQYLAYLHNAADQLRGEGATLDFFSN
GQYRNPAVVRVAGYGYQKGFGGHFHNDNSVAALLDIPGLTVASPSHPDDAAAMLRACAAA
AAAAGTLSVFLEPIALYHTRDLHTGGDGGWLSTGEAVDPTIGVGRTHGDGEDLTLISFAN
GVPMSLRIAARLAQRGVNARVLDLRWLAPLPVDDILREAEATGRVLIVDETRRSGGVGQS
VLAALVENGFAGAISRVSSADSFIPLGDAALRVLLDEETVEQHALKLTSA
NT seq
2133 nt
NT seq
+upstream
nt +downstream
nt
atggccgaacccattgacgactacttcgtcgccgcgctgcgggcccatccgggttccgca
gccggcgaaccgggcctttcggtcaaggaggcgctggcggtcttcgacgcgcagatcggc
agcaggcacctggacctggcggcccgggcgttgcgcgctcgcgggcgcggctactacacc
atcggctccgccggccacgagtccaacgcggtggtggccgcggcgctgcgcgcagacgat
ccggccttgctgcactaccgatccggcgggttcttcctggcccgcgccgcgcagcgggac
tccgagcgcgacgcattgcgcgatgtgctgctgggcatggtggcagcgaccgacgagccc
atcgccggcggccggcacaaggtgtgggggcgccacgacctggcggtgatcccgcagacc
tcgaccatcgcctcgcacctgccgcgggcgttcgggatggccttcacgctggccgccgcg
caacgcagcgcggactgcccgtggccggcggatgcggtggtggcgtgcagctttggtgac
gcgtcggcgaatcattccaccgcggtcggcgcgatcaacgccgcccgcaacgcggcgttc
cgcgggctgcccgtgccgctgctgctggtgtgcgaggacaacggcatcgggatcagcacc
cgcaccccggccggttggatcgcgtccagctacgcgaatctgcccggactggcctacttc
gaggccgacggcgccgacgtggcgggggccgcggccgccgccacggctgccgccgactgg
gtgcgcggcaggcgcagcccggcgttcctgcacctgcgcaccgtccggttgatggggcac
gccggctccgacgtcgaaaccggttaccgcacaacggcggagatcagcgccgactacccg
cgggacccggtgctggccaccgcccgctggctgatcgagcacggcggcctggcgcccgag
gaggtgctcggactatatgaggacaagcgggaggtggtcgcggcactggccgacgaggtc
tgcgagctgccgcaactcgacagcgccgaggccgttctcacgccgctgaccaccaccgcc
caacgcgccagggacgtgtcctcggccacccgttccaccggcgattccgggttgacgttg
gcccagtccatcaacgccgcgctggtcgatgttctggaaacccattccggagcaaccctt
ttcggcgaggacgtggcacgcaagggtggcgtgtacggggtcacccgcggactgcagaag
cgcttcgggcggtcccgggtgttcgacaccatcctcgatgagcagaccattctcggcctg
gcgctcggagcgggcctcaacgggatgttgcccatcccggaaattcagtacctggcctat
ctgcacaatgccgccgatcagctccgcggcgagggcgccaccctggacttcttctccaat
ggccagtaccgcaacccggcggtggtccgggtcgccggctacggctaccagaagggcttc
ggcgggcacttccacaacgacaactcggtggccgcgctgctggacatccccggtctgacg
gtggcgtccccgtcgcatcccgacgacgccgcggcgatgctgcgcgcctgcgcggccgct
gccgcggcggccggaacgctgagcgtgttcctggaacccattgcgctgtaccacacccga
gacctgcacaccggcggtgacggcggctggctgtccaccggcgaagccgtcgatcccacg
atcggggtggggcgcacccacggcgacggcgaggatttgacgctgatcagcttcgccaac
ggcgtgccgatgagcctgcggatcgcggcgcggttggcgcagcgcggcgtcaacgcccgg
gtgctggatctgcggtggctggcgccgctgccggtcgacgacattctgcgcgaggcggag
gcgaccggacgggtgctcatcgtcgacgagacccgccgcagcggcggcgtcggccagagc
gtgctcgccgccctcgtggagaacggcttcgccggggcgatctcgcgggtcagcagcgcc
gacagtttcatcccgctcggcgacgcggcactgcgcgtgctgctcgacgaagagaccgtc
gagcagcacgcgctcaagctcacgtcggcgtga
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