Mycolicibacterium brumae: L2Z93_001095
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Entry
L2Z93_001095 CDS
T08531
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mbrm
Mycolicibacterium brumae
Pathway
mbrm00290
Valine, leucine and isoleucine biosynthesis
mbrm00660
C5-Branched dibasic acid metabolism
mbrm01100
Metabolic pathways
mbrm01110
Biosynthesis of secondary metabolites
mbrm01210
2-Oxocarboxylic acid metabolism
mbrm01230
Biosynthesis of amino acids
Module
mbrm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mbrm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
L2Z93_001095 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
L2Z93_001095 (leuC)
Enzymes [BR:
mbrm01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
L2Z93_001095 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
L2Z93_001095 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
UWW08052
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Position
1097127..1098548
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AA seq
473 aa
AA seq
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MSEQPQNKPRTLSEKVWADHVVASEPGEPDLIYIDLHLVHEVTSPQAFDGLRMAGRPVHR
PDLTIATEDHNVPTVDIDKPIADPVSRTQVETLRRNCEEFGVRLHAMGDRDQGIVHIIGP
QLGLTQPGMTIVCGDSHTSTHGAFGSLGMGIGTSEVEHVMATQTLPLRPFKTMAVNVDGV
LPAGVSAKDIILAVIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMV
APDEITYEYLKGRPHAPTGADWDNAVAAWDRLRTDPGAEFDTEVYLDAAELSPFVTWGTN
PGQGVALSAAVPDPEMMTDDAEKQAAEKALAYMDLTPGTPMRDIAVDTVFVGSCTNGRIE
DLRTVAEVLRGRRVADGVRMLIVPGSVGVRLQAESEGLGEVFEAAGAEWRQAGCSMCLGM
NPDQLAPGERSASTSNRNFEGRQGKGSRTHLVSPAVAAATAVRGTLSSPADLA
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgtccgaacagccgcagaacaagccgagaaccctgtctgaaaaggtgtgggccgaccac
gtcgtcgcctccgaacccggcgaacccgacctgatctacatcgacctgcacctcgtgcac
gaggtcaccagcccgcaggcgttcgacggcctgcgaatggccggccgaccggtgcaccgc
ccggatctgaccatcgccaccgaagaccacaacgtgccgacggtggacatcgacaagccg
atcgccgacccggtgtcgcgcacccaggtcgagacgctgcgccgcaactgcgaggagttc
ggcgtccggctgcacgcgatgggcgaccgggaccagggcatcgtgcacatcatcggcccg
cagctgggcctgacccagcccggtatgacgatcgtctgcggcgacagccacacctccacc
cacggcgccttcggctcgctgggcatgggcatcggcacctccgaggtggagcatgtgatg
gccacccagaccctgccgctgcgcccgttcaagaccatggcggtcaacgtcgacggcgtg
ctgccggccggcgtcagcgccaaggacatcatcctggcggtgatcgccaagatcggcacc
ggcggcgggcagggccacgtcatcgaataccggggcagcgccatcgaatcgctgtccatg
gagggccggatgacgatctgcaatatgagcatcgaggccggcgcgcgagccggcatggtc
gcccccgacgagatcacctacgaatacctgaagggccgcccgcacgcgccgaccggcgcc
gactgggacaacgcggtggccgcgtgggaccggctgcgcaccgacccgggggccgaattc
gacaccgaggtgtacctggacgccgcggaactgagcccattcgtcacctggggcaccaat
ccggggcagggcgtggcgctgtcggcggcggtgcccgatccggagatgatgaccgacgac
gccgagaagcaggccgccgagaaggcgttggcctacatggatttgacgcccggcaccccg
atgcgcgacatcgccgtcgacaccgtgttcgtcggctcttgcaccaacggacgcatcgag
gacctgcggacggtggccgaggtgctgcgcggccgccgggtcgccgacggcgtgcggatg
ctgatcgtgcccggctcggtcggggtgcggttgcaggccgaatccgaaggactcggtgag
gtgttcgaagcggccggtgccgagtggcggcaggccggctgctcgatgtgcctgggcatg
aaccccgatcagctggccccgggcgagcgcagcgcctccacctcgaaccgcaatttcgag
ggccgccaaggcaaaggctcgcggacgcacctggtttccccggcggtggccgccgcgacc
gcggtgcgcggaacgctgtcctcgccggcggacctggcctag
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