Mycobacterium tuberculosis variant bovis BCG Tokyo 172: JTY_1329
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Entry
JTY_1329 CDS
T00864
Symbol
thrA
Name
(GenBank) homoserine dehydrogenase
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
mbt
Mycobacterium tuberculosis variant bovis BCG Tokyo 172
Pathway
mbt00260
Glycine, serine and threonine metabolism
mbt00270
Cysteine and methionine metabolism
mbt00300
Lysine biosynthesis
mbt01100
Metabolic pathways
mbt01110
Biosynthesis of secondary metabolites
mbt01120
Microbial metabolism in diverse environments
mbt01230
Biosynthesis of amino acids
Module
mbt_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
mbt_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
mbt00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
JTY_1329 (thrA)
00270 Cysteine and methionine metabolism
JTY_1329 (thrA)
00300 Lysine biosynthesis
JTY_1329 (thrA)
Enzymes [BR:
mbt01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
JTY_1329 (thrA)
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Motif
Pfam:
Homoserine_dh
NAD_binding_3
ACT
ACT_AHAS_ss
GFO_IDH_MocA
Motif
Other DBs
NCBI-ProteinID:
BAH25617
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Position
1448787..1450112
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AA seq
441 aa
AA seq
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MPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE
LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA
AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS
ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS
AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR
LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN
VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA
LDDLDVVQGVSSVIRLEGTGL
NT seq
1326 nt
NT seq
+upstream
nt +downstream
nt
gtgcccggtgacgaaaagccggtcggcgtagcggtactcggtttgggcaacgtcggcagc
gaggttgtccgcatcatcgagaacagcgccgaggatctcgcggctcgtgtcggtgcccca
ttggtcctgcggggcatcggcgtgcgccgcgtgacgaccgatcgcggcgtgccgatcgaa
ttgttgaccgacgacattgaagagctcgtggcccgcgaggatgtcgatatcgtggtggaa
gtgatggggccggtggaaccgtcgcgcaaggcgatcctgggcgcccttgagcgcggcaag
tccgtcgttacggcgaacaaggctttactcgccacctccaccggcgaattggcacaggcc
gccgaaagcgcccatgttgatctgtatttcgaggcggccgtggcgggcgccattccggtc
atccgtccgctcacccagtcgctggccggcgacacggtgctgcgagtggccgggatcgtc
aacggcaccaccaactacatcctctcggcgatggacagcaccggcgctgactatgccagc
gccctggccgacgcaagtgcgctgggctatgcggaggctgatcccaccgcagacgtcgaa
ggctacgacgccgcggccaaggcagcgatcctggcatccattgccttccacacccgggtg
accgcagacgacgtgtatcgcgaaggcatcaccaaggtcactccggccgacttcggatcc
gcgcacgcgctgggttgcaccatcaaactgctgtcgatctgtgagcgcataaccaccgac
gaaggttcgcagcgggtatcggcccgcgtctatccggccctggtacctctgtcgcatccg
cttgccgcggtcaacggcgcgttcaatgccgtggtggtcgaggccgaggccgcgggccgg
ctgatgttctacggccagggcgcgggcggcgcgccgaccgcctctgcggtgaccggtgac
ctagtgatggccgcccgcaaccgggtactcggcagccgcggcccccgtgagtctaaatac
gctcaacttccggtggcaccaatgggtttcattgaaacgcgctattacgtcagcatgaac
gtcgccgacaagccgggcgtcttgtccgcggtggcggcggaattcgccaaacgcgaggtg
agcatcgccgaggtgcgccaggagggcgttgtggacgaaggtggtcgacgggtgggagcc
cgaatcgtggtggtcacgcacctcgccactgacgccgcactctcggaaaccgttgatgca
ctggacgacttggatgtcgtgcagggtgtgtccagcgtgatacgactggaaggaaccggc
ttatga
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