Mycobacterium tuberculosis variant bovis BCG Tokyo 172: JTY_2885
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Entry
JTY_2885 CDS
T00864
Symbol
gcpE
Name
(GenBank) 4-hydroxy-3-methylbut-2-enyl diphosphate synthase
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
mbt
Mycobacterium tuberculosis variant bovis BCG Tokyo 172
Pathway
mbt00900
Terpenoid backbone biosynthesis
mbt01100
Metabolic pathways
mbt01110
Biosynthesis of secondary metabolites
Module
mbt_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
mbt00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
JTY_2885 (gcpE)
Enzymes [BR:
mbt01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
JTY_2885 (gcpE)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
JTY_2885 (gcpE)
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Gene cluster
GFIT
Motif
Pfam:
GcpE
MR_MLE_C
Zn_ribbon_9
Motif
Other DBs
NCBI-ProteinID:
BAH27163
UniProt:
C1AFY4
LinkDB
All DBs
Position
complement(3126127..3127290)
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AA seq
387 aa
AA seq
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MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL
TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN
IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE
HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR
GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG
LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE
EAMRLAAEMGEQDPGATPSGSPIVTVS
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
gtgactgtaggcttgggcatgccgcagcccccggcacccacgctcgctccccggcgcgcc
acccgtcagctgatggtcggcaacgtcggcgtgggcagtgaccatccggtctcggtgcaa
tcgatgtgcaccaccaaaacccacgacgtcaactcgacattgcaacaaatcgccgagctg
accgcggccggatgcgacatcgtgcgggtggcctgcccgcgccaggaggacgccgacgcg
ctggccgagatcgcccggcacagccagatcccggtagtcgcggacatacatttccagccg
cgctacatattcgccgccatcgacgctggatgtgccgcggtgcgggtcaacccgggcaac
atcaaggagtttgacggccgggtgggtgaggtcgccaaggcggcgggtgcggccgggatc
ccgatccgaatcggtgtcaacgccggttcgctggacaaacggttcatggagaagtatggc
aaagccacgcccgaggcgctggttgagtcggcgctgtgggaggcttcgcttttcgaggag
catggcttcggtgacatcaagatcagcgtcaagcacaacgacccggtggtgatggtcgcc
gcctacgagctgcttgctgcacggtgcgactacccactgcacctcggtgtcaccgaggcc
ggccctgctttccagggcaccatcaagtccgcggttgccttcggcgcgttgctgtcgcgg
ggcataggcgacaccatccgggtgtcgttgtcggccccgccggtcgaggaagtcaaggtg
ggcaatcaggttctcgagtcgttgaacctgcggccgcgttcgctcgagatcgtgtcttgc
ccgtcgtgcggtcgcgcgcaagtcgacgtctacaccctggccaacgaggtaaccgccggc
ctggatggtctcgatgtgccgttgcgggtggccgtgatggggtgtgtcgtcaatggtccg
ggtgaagcacgtgaggccgacctgggcgtggcgtccggcaacggcaaaggtcagatcttt
gtacggggcgaagtgatcaagaccgtgcccgaagcacagatcgtcgagacgctgatcgag
gaggcgatgcggctggccgccgaaatgggcgagcaagatccgggcgcgacaccgagcggt
tcgcctattgtgaccgtaagctga
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