Mycobacterium tuberculosis variant bovis BCG ATCC 35743: BCGT_2335
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Entry
BCGT_2335 CDS
T03796
Name
(GenBank) Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mbx
Mycobacterium tuberculosis variant bovis BCG ATCC 35743
Pathway
mbx00280
Valine, leucine and isoleucine degradation
mbx00640
Propanoate metabolism
mbx00785
Lipoic acid metabolism
mbx01100
Metabolic pathways
mbx01110
Biosynthesis of secondary metabolites
mbx01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mbx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
BCGT_2335
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
BCGT_2335
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BCGT_2335
Enzymes [BR:
mbx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
BCGT_2335
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
MCD
Motif
Other DBs
NCBI-ProteinID:
AHM08255
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Position
complement(2485455..2486528)
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AA seq
357 aa
AA seq
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MLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGEL
ALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQF
TTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFT
TPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARA
RAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRL
EEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgttgatgtctgtcgatcttgagccggtgcaactcgtcggcccggacggtacgccgacg
gccgaacgccgctaccaccgtgaccttcctgaggaaacgctgcgttggctctacgagatg
atggtggtcacccgcgagctggataccgaattcgtcaatctgcagcgccagggggagctg
gcgttgtacacgccctgtcgcgggcaggaagccgcgcaggtgggtgcggcggcttgccta
cgcaaaaccgactggttgttcccccaataccgagaattgggcgtctacctagtgcgtggc
atcccgcctggacatgttggggtcgcgtggcgtggaacctggcacggcgggctgcaattc
accacgaagtgctgtgcaccgatgtcggttcccatcggcacccagaccttgcacgcggtg
ggcgcggcgatggccgcgcaacgcctggacgaggactccgtgacggtggcctttctgggc
gacggcgccaccagcgagggcgacgtacatgaggcgctcaatttcgcggcggtgttcacc
acaccgtgcgtgttctacgtgcagaacaaccagtgggcaatctcgatgccggtatccagg
cagaccgccgcaccatctatcgcgcacaaggcgattggctacgggatgccaggcatccgg
gtggacggcaacgacgtgctggcatgctatgcggtgatggccgaagctgccgctcgggct
cgggccggcgacggtccaacgctgatcgaggcggtcacttaccgtcttggtccgcacacc
accgccgatgatccaacccggtaccgcagccaggaggaggtggaccgctgggcgacgctg
gacccgattccgcgctatcgcacttacttacaagatcagggcctgtggtcgcaacgcctc
gaggaacaggtgacggctcgggcaaaacacgtgcggtccgagctacgcgacgcggtcttt
gatgcgcctgacttcgacgtcgatgaggtgttcaccacggtgtacgccgaaatcacaccc
gggttgcaggcgcagcgcgaacagctgcgtgccgaactggcgcggactgactga
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