Methylacidiphilum caldifontis: IT6_10320
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Entry
IT6_10320 CDS
T09436
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mcao
Methylacidiphilum caldifontis
Pathway
mcao00300
Lysine biosynthesis
mcao00550
Peptidoglycan biosynthesis
mcao01100
Metabolic pathways
mcao01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mcao00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
IT6_10320
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
IT6_10320
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
IT6_10320
Enzymes [BR:
mcao01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
IT6_10320
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QSR88724
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Position
2232722..2234101
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AA seq
459 aa
AA seq
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MELLSIEEIAKWVDGEIVGAKTPVLVSDISTDSRTLKTGDCFIALRGRNFDGMDFVADAV
QKGAVAVVVDREPRSSASLSIPVIRVRDSLEALQRLARFYRKELKAKIVAITGSSGKTST
KEMVSSVLSQKYKTVCTSGNFNNQIGLPLSLLRMDKTTEYGVFELGTNHPGEIGVLAQLA
APDIVIITNIGSAHVGNFGSVDTLAKEKTDLLSFVSAKGVAILSDDDYWSKRLHTRSVGQ
VIWVGNQQNSVCWLDRLEMTERGIRYGICRHKEKFEVFLPTVSREMAKNSLFAAAVGFLS
CLSSEEIAAGLRKTYFPAGRLTVHPIKNGFLIDDSYNANPESMLSALRALIEFPFPSKKI
AIMGSMGELGSKSSAFHSMIGSFAGGLPLWSVILIGPNWKDMLEGFQSSSFPTDCIFGAE
DIEEAYYCLRKLLNGRVTLLVKGSRFLKLDRIVEKVLCL
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggagttgctctcgattgaggaaattgcgaagtgggttgatggagaaattgttggggct
aaaactccggtattggtttcagatatctctactgactctagaacgctaaaaacgggtgat
tgttttatagccttaaggggaagaaatttcgatggcatggattttgtcgctgatgcggta
caaaagggggcagttgccgtggtggttgatcgagaaccccgttcttcggcctctctatct
attccggtcattagggttagggatagcttagaggccttacaacggcttgcccgattttat
agaaaagaacttaaggctaagatcgtagccattacaggcagtagcggcaaaacaagcact
aaggaaatggtcagtagcgttttaagtcaaaaatacaaaacggtttgtacgtctgggaat
ttcaacaatcagataggtttgcctctttctcttttacggatggataaaacaaccgaatat
ggggtttttgaattaggaacaaatcatccgggagaaattggagttttagctcaattggct
gcacctgatatcgttataataacgaatattggcagtgcccatgtaggcaattttggttcg
gttgacaccctagccaaagaaaagaccgatctgcttagttttgtgtcagcaaagggcgtg
gcgattctaagtgatgatgattattggtcaaagcgactacatactcgcagtgttggacag
gttatatgggtaggaaaccagcaaaattcagtttgttggcttgaccgcttagagatgacg
gaaaggggaattcgatacggtatttgccggcataaagaaaaatttgaagtttttctgccc
accgtttctagagaaatggcaaaaaattctctttttgctgcagcggttgggtttttatct
tgcctttcttctgaagaaatagcagccggtcttcgaaaaacatactttcctgcgggtcgg
ctgactgttcatcctattaaaaatggatttttaatcgacgacagctataatgcaaatccc
gaatcgatgttaagtgccttaagggcgctgattgaatttccttttccttcaaaaaagatc
gctataatgggatccatgggtgagttaggatcaaaatcgagcgcatttcattccatgatc
ggatcgtttgctggaggactgcctctttggtcagtgattttgattggtcctaattggaaa
gatatgttggaggggtttcaaagctcttctttcccgacagattgtatttttggagcagaa
gatatagaagaagcttattattgtttgcgtaaacttttaaacggaagggttacccttctt
gtgaaaggttcaagatttttaaaacttgacaggattgtcgaaaaggttctttgtctttag
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