| Entry |
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| Symbol |
NSD2
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| Name |
(RefSeq) histone-lysine N-methyltransferase NSD2 isoform X1
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| KO |
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| Organism |
mcc Macaca mulatta (rhesus monkey)
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| Pathway |
| mcc05202 | Transcriptional misregulation in cancer |
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| Brite |
KEGG Orthology (KO) [BR:mcc00001]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100429321 (NSD2)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100429321 (NSD2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:mcc03036]
100429321 (NSD2)
Enzymes [BR:mcc01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase
100429321 (NSD2)
Chromosome and associated proteins [BR:mcc03036]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100429321 (NSD2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
5:1929979..2043867
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| AA seq |
1365 aa
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
KEAGIAAESFGEMAESSGVGEEAAENPKSAREEGVPMKRRRRAKLCSSAETLESDPDVVK
STPQKTAEADPRRGVASPPGRKKTTASTPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRTQDPTEDVE
VEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
NRASTAASSALGFSKSSSPSASLTENEVSDSLGDEPSESPYESADETQTEVSVSSKKSER
GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHFCPNSFCKEHQDGTAFSCTPDGR
SYCCEHDLGAASVRSAKTEKPPPEPGKPKGKRRRRRGWRRVTEGK |
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| NT seq |
4098 nt +upstreamnt +downstreamnt
atggaatttagcatcaagcagagtcccctttctgttcagagtgttgtaaagtgcataaag
atgaagcaggcaccagaaatcctcggcagtgccaatgggaagactccgagctgtgaggtg
aatcgcgagtgttctgtgttcctcagcaaagcccagctctccagcagcctgcaggagggg
gtcatgcagaagtttaacggccacgacgccctgccctttattccagccgacaagctgaaa
gatcttacttcccgggtgtttaatggagaacctggtgcacacgatgccaaactgcgtttt
gagtcccaggaaatgaaagggattgggacaccacctaacactacccctatcaaaaatggc
tctccagaaattaagctgaagatcaccaaaacgtacatgaatgggaagcctctctttgaa
tcttccatttgtggtgacagtgctgctgatgtgtctcagtcagaagaaaatggacaaaaa
ccagaaaacaaggcaagaaggaacaggaagaggagcataaaatatgactccttgctggag
cagggccttgtggaagcagctcttgtgtctaagatctcgagtccttcagataaaaagatt
ccagctaagaaagagtcctgtccaaacactggaagagacaaagaccacctgttgaaatac
aatgtcggtgatttggtgtggtccaaagtgtcgggttacccttggtggccttgcatggtt
tctgcagatccactccttcacagctataccaaacttaaaggtcagaaaaagagtgcacgc
cagtatcacgtacagttctttggtgacgccccagaaagagcttggatatttgagaagagc
ctcgtagcttttgaaggagaaggacagtttgaaaaattatgccaggaaagtgccaagcag
gcacccacgaaagctgagaaaattaagctattgaaacctatttcagggaaattgagggcc
cagtgggaaatgggcattgttcaagcagaagaagctgcaagcatgtcagtggaggagcgg
aaagccaagttcacctttctatacgtgggggaccagcttcacctcaaccctcaagtagcc
aaggaggctggcattgctgcagagtctttcggagaaatggcagagtcctcaggagtcggt
gaagaagctgctgaaaaccccaagtctgcgagagaagagggcgttcccatgaagagaagg
cggagggccaaactgtgtagctctgcagagaccctggagagtgaccccgatgtagtgaag
agtactcctcaaaagacggcagaggctgaccccagaagaggagtcgcgtctcctcctggg
aggaagaagaccacagcctctacgccacgaagcaggaagggagatgcagcatcccagttt
ttggtcttctgtcaaaaacacagggatgaggtggtggctgagcacccagatgcttcaggt
gaggagattgaagagctgctcaggtcacagtggagtctgctgagtgagaagcagagagcg
cgctataacaccaagtttgccctggtggcccctgtccaggctgaagaagactctggtaac
gtaaatgggaaaaaaagaaaccacacaaagaggacacaggaccctacagaagatgttgaa
gttgaggacacacccaggaaaagactcaggacagacaagcacagtcttcggaagagagac
acaatcactgacaaaacggccagaacaagctcttacaaggccatggaggcagcctcctcg
ctcaagagccaggcagcaacgaaaaatctgtctgatgcatgcaaaccactgaagaagcga
aatcgggcttccacggcagcatcttcagctcttgggtttagcaaaagttcatctccttct
gcatccttaactgagaatgaggtctcggacagcctgggagacgagccctcggagtcccca
tatgaaagtgcagatgaaacacaaactgaagtgtctgtctcatccaaaaagtctgagcga
ggagttactgccaaaaaggagtacgtgtgccagctgtgtgagaagccaggcagcctcctg
ctctgtgaaggaccctgctgcggagctttccacctcgcctgccttgggctttcccggagg
ccagaagggaggttcacctgcagcgagtgtgcctcagggattcactcgtgtttcgtgtgt
aaagagagcaagacagatgttaagcgctgtgtggtaactcagtgtggaaaattttaccat
gaggcttgtgtgaaaaaataccctctgactgtatttgagagccgaggtttccgctgcccc
cttcacagctgtgtgagctgccacgcttccaacccttcaaacccaaggccgtcaaaaggt
aaaatgatgcggtgtgtccgctgccccgttgcctatcacagcggggatgcttgtctggca
gcaggatgctcagtgatcgcctccaacagcatcatctgcactgcccacttcactgctcgg
aaggggaagcgacaccacgcccacgtcaacgtgagctggtgctttgtgtgctccaaaggg
gggagccttctgtgctgcgagtcctgcccagcagccttccaccctgactgcctgaacatc
gagatgcctgacggcagctggttctgcaatgactgcagggctgggaagaagctgcacttc
caggatatcatttgggtgaaacttgggaactacagatggtggccggcagaagtttgccat
cccaaaaatgttcccccaaatattcagaaaatgaagcacgagattggagaattccctgtg
tttttctttgggtctaaagattattactggacgcatcaggcgcgagtgttcccgtacatg
gagggggaccggggcagccgctaccagggggtcagagggatcggaagagtcttcaaaaac
gcactgcaagaagccgaagctcgttttcgtgaaattaagcttcagagggaagcccgagaa
acacaggagagcgagcgcaagcccccaccatacaagcacatcaaggtgaataagccttac
gggaaagtccagatctacacagcggatatttcagaaatccctaagtgcaactgcaagccc
acagatgagaatccttgtggctttgattcggagtgtctgaacaggatgctgatgtttgag
tgccacccgcaggtgtgtcccgcaggcgagttctgccagaaccagtgcttcaccaagcgc
cagtacccagagaccaagatcatcaagacagatggcaaagggtggggcctggtcgccaag
agggacatcagaaagggagaatttgttaatgagtacgtcggggagctgatcgatgaggag
gagtgcatggcgagaatcaagcacgcacacgagaacgacatcacccacttctacatgctc
actatagacaaggaccgtataattgacgctggccccaaaggaaactactctcgatttatg
aatcacagctgccagcccaactgtgagaccctcaagtggacagtgaacggggacactcgt
gtgggcctgtttgccgtctgcgacattcctgcagggacggagctgacttttaactacaac
ctcgattgtttgggcaatgaaaaaacggtctgtcggtgtggagcctccaattgcagtgga
ttcctcggggatagaccaaagacctcaacgaccctttcttcagaggaaaagggcaaaaag
accaagaagaagaccaggcggcgcagagcaaaaggggaagggaagcggcagtcagaggac
gagtgcttccgctgcggcgacggcgggcagctggtgctgtgtgaccgcaagttctgcacc
aaggcctaccacctgtcctgcctgggcctgggcaagcggcccttcgggaagtgggaatgt
ccttggcatcattgtgacgtgtgtggcaaaccttcaacttcattttgccacttctgcccc
aattcattctgtaaggagcaccaggacgggacagccttcagctgcaccccggacgggcgg
tcctactgctgtgagcatgacttaggggcggcatcggtcagaagcgccaagactgagaag
cctccgccagagccagggaagccaaaggggaagaggcggcggcggaggggctggcggaga
gtcacggagggcaaatag |
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