Macaca mulatta (rhesus monkey): 574130
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Entry
574130 CDS
T01028
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04217
Necroptosis
mcc04380
Osteoclast differentiation
mcc04620
Toll-like receptor signaling pathway
mcc04621
NOD-like receptor signaling pathway
mcc04630
JAK-STAT signaling pathway
mcc04658
Th1 and Th2 cell differentiation
mcc04659
Th17 cell differentiation
mcc05145
Toxoplasmosis
mcc05160
Hepatitis C
mcc05161
Hepatitis B
mcc05162
Measles
mcc05164
Influenza A
mcc05165
Human papillomavirus infection
mcc05167
Kaposi sarcoma-associated herpesvirus infection
mcc05168
Herpes simplex virus 1 infection
mcc05169
Epstein-Barr virus infection
mcc05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
574130 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
574130 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
574130 (TYK2)
04621 NOD-like receptor signaling pathway
574130 (TYK2)
04658 Th1 and Th2 cell differentiation
574130 (TYK2)
04659 Th17 cell differentiation
574130 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
574130 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
574130 (TYK2)
05160 Hepatitis C
574130 (TYK2)
05171 Coronavirus disease - COVID-19
574130 (TYK2)
05164 Influenza A
574130 (TYK2)
05162 Measles
574130 (TYK2)
05168 Herpes simplex virus 1 infection
574130 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
574130 (TYK2)
05169 Epstein-Barr virus infection
574130 (TYK2)
05165 Human papillomavirus infection
574130 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
574130 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
574130 (TYK2)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
574130 (TYK2)
Protein kinases [BR:
mcc01001
]
Non-receptor tyrosine kinases
JAK family [OT]
574130 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
574130
NCBI-ProteinID:
XP_028695770
Ensembl:
ENSMMUG00000003110
UniProt:
F7DRD4
LinkDB
All DBs
Position
19:complement(10110204..10144759)
Genome browser
AA seq
1190 aa
AA seq
DB search
MPLRHRGTTRGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI
AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRMRFYFRNWHGMNPQEL
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFK
NESLGMAFLHLCHLALCRGVPLEEVAKKTSFKDCIPLSFRRQIRQHSALTRLRLRNVFRR
FLQDFQPDRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGEAP
TDPGPESAARPPTHEVLVTGTGGIQWWPVQEEVNKEEGSSGGSGRNPQASLSGKKAKAHK
AIGQPADRLREPLWAYFCDFRDITHVVLKECCVSIHRQDNKCLELSLPSRAAALSFVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRPEDGLYLIQWSTSHP
YRLILTVAQRSQAPDGTQSLRLRKFPIEQQAGAFVLEGWGRSFPSVRELGAALQGCLLRA
GDDCFSLRRRCLPQPGETSNLIIMRGARASTRTLNLSQLSFHRVDQKEITQLSHLGQGTR
TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS
LMSQVSHVHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS
ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWMA
PECLPGGPNSLSIAMDKWGFGATLLEICFDGEAPLQSRSSSEKEHFYQRQHRLPEPSCPE
LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHTLPDLADVLIVNPDSSASDPTVFHKRYL
KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIEILRTLYHE
HIVKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQ
HYIHRDLAARNVLLDNDKLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK
FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGITQGQMTVLRLTELLERGERLPRP
DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
NT seq
3573 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgcgccatcgggggacgaccaggggcagcaagcccgttggggatggagcccag
cccatggctgccatgggaggcctgaaggtgcttctgcactgggctggtccaggcggcgga
gagccctgggtcactttcagcgagtcatcgctgacagctgaggaagtctgcatccacatt
gcacataaagtcggtatcactcctccttgtttcaatctcttcgccctcttcgatgctcag
gcccaagtctggttgcccccaaaccacatcctagagatccccagagatgcaagcctgatg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagctg
gctgtgtaccgttgtgggcccccaggaaccgaggcatcctcagatcagacagcacagggg
atgcaactcctggacccagcctcatttgagtacctctttgagcagggcaagcatgagttt
gtgaatgacgtggcatcactgtgggagctatcgagcgaggaggagatccaccactttaag
aatgagagcctgggcatggcctttctgcacctctgtcacctcgctctctgccgtggtgtc
cccctggaggaggtggccaagaaaaccagcttcaaggactgtatcccgctctccttccgt
cggcagatccggcagcacagcgccctgacccggctgcgccttcggaacgtcttccgcagg
ttcctgcaggacttccagccggacagactctcccagcagatggtcatggtcaaatacctg
gccacactcgaacggctggcaccccgctttggcacagagcgtgtgcccgtgtgccacctg
aggctgctggcccaggcagagggagagccctgctacatccgggacagtggggaggcccct
acagaccctggccctgagtctgctgctagacccccaacccatgaggtgctggtgacaggc
actggtggcatccagtggtggccagtacaggaggaggtgaacaaggaggagggttctagt
ggcggcagcggcaggaacccccaagccagcctgtctgggaagaaggccaaggctcacaag
gcaatcggccagccggcggacaggctgcgggagccactgtgggcctacttctgtgacttc
cgggacatcacccacgtggtgctgaaagagtgctgtgtcagcatccaccggcaggacaac
aagtgcctggagctgagcctgccttcccgggctgcagcgctgtccttcgtgtcgctggtg
gacggctatttccgcctgacggccgactccagccactacctgtgccacgaggtggctccc
ccacggctggtgatgagcatccaggatgggatccatggacccctgctggagccgtttgtg
caggccaagctgcggcccgaggacggcctgtacctcattcagtggagcaccagccacccc
taccgcctgatcctcacagtggcccagcgtagccaggcaccagacggcacacagagcttg
cggctccggaagttccccattgagcagcaggccggggcctttgtgctggagggctggggc
cggtccttccccagcgttcgggaacttggggccgccttgcagggctgcttgctgagggcc
ggggacgactgcttctctctgcgtcgccgttgcctgccccaaccaggagaaacctccaac
ctcatcatcatgcggggggctcgggccagcaccaggacactcaacctcagccagctcagc
ttccaccgggttgaccagaaggagatcacccagctgtcccacttgggccagggcacaagg
accaacgtgtacgagggccgcctgcgagtggagggcagtggggaccctgaggagggcaag
atggacgatgaggaccccctcgtgcctggaagggaccgtgggcaggagctacgagtggtg
ctcaaagtgctggacccgagtcaccatgacatcgccctggccttctatgagacagccagc
ctcatgagccaggtctcccacgtgcacctggccttcgtgcacggcgtctgtgtgcgaggc
cctgaaaatatcatggtgacagagtacgtggagcacggacccctggacgtgtggctgcgg
agggagcggggccatgtgcccatggcttggaagatggtggtggcccagcagctagccagc
gccctcagctacctggagaacaagaacctggtacatggtaatgtgtgtggccggaacatc
ctgctggctcggctggggctggcagagggcacgagccccttcatcaagctgagtgatccc
ggcgtgggcctcggcgccctctccagggaggagcgggtggagcggatcccctggatggcc
cccgaatgcctcccaggtgggcccaacagcctaagcattgccatggacaagtgggggttt
ggtgccaccctcctggagatctgctttgatggagaggccccgctgcagagccgcagctcc
tccgagaaggagcatttctaccagaggcagcaccggctgcccgagccctcctgcccagag
ctggccacactcaccagccagtgtctgacctatgagccaacccagaggccttcattccgc
accatcctgcgtgacctcacccggctgcagccccacactcttccagatcttgctgatgtc
ttgattgtgaacccggactcatcggcgtcagaccctacggttttccacaagcgctatttg
aaaaagatccgagatctgggcgagggtcacttcggcaaggtcagtttgtactgctacgat
ccgaccaacgacggcactggcgagatggtggcggtgaaagcccttaaggcagactgcggc
ccccagcaccgctcgggctggaagcaggagattgagattctgcgcacgctctatcacgag
cacatcgtcaagtacaagggctgctgcgaggatcaaggcgagaagtcgctgcagctggtc
atggagtacgtgcccctgggcagcctccgagactacctgccccggcacagcgtcgggctg
gcccagctgctgctcttcgcccagcagatctgcgagggcatggcctatctgcacgcgcag
cactacatccaccgagacctagccgcgcgcaacgtgctgctggacaacgacaagctggtc
aagatcggggactttggcctagccaaggccgtgcccgaaggccacgagtactaccgcgtg
cgcgaggatggggacagccccgtgttctggtatgccccagagtgcctgaaagagtataag
ttctactatgcgtccgatgtctggtccttcggggtgaccctgtatgagctgctgacgcac
tgtgactccagccagagcccccccacgaaattccttgagctcataggcatcacccagggt
cagatgacagttctgagactcaccgagttgctggaacgaggggagaggctgccacgacct
gacaaatgtccctgtgaggtctatcatctcatgaagaactgctgggagacagaggcgtcc
ttccgcccaaccttcgagaacctcatacccatcctgaagacagtccatgagaagtaccaa
ggccaggccccttccgtgttcagtgtgtgctga
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