Macaca mulatta (rhesus monkey): 574227
Help
Entry
574227 CDS
T01028
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00010
Glycolysis / Gluconeogenesis
mcc00020
Citrate cycle (TCA cycle)
mcc00620
Pyruvate metabolism
mcc00785
Lipoic acid metabolism
mcc01100
Metabolic pathways
mcc01200
Carbon metabolism
mcc01210
2-Oxocarboxylic acid metabolism
mcc04066
HIF-1 signaling pathway
mcc04922
Glucagon signaling pathway
mcc05230
Central carbon metabolism in cancer
mcc05415
Diabetic cardiomyopathy
Module
mcc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
574227 (PDHB)
00020 Citrate cycle (TCA cycle)
574227 (PDHB)
00620 Pyruvate metabolism
574227 (PDHB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
574227 (PDHB)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
574227 (PDHB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
574227 (PDHB)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
574227 (PDHB)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
574227 (PDHB)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
574227 (PDHB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
574227
NCBI-ProteinID:
NP_001182323
Ensembl:
ENSMMUG00000015672
UniProt:
F6R4J1
G8F1Q0
LinkDB
All DBs
Position
2:complement(114592202..114598238)
Genome browser
AA seq
359 aa
AA seq
DB search
MAAVSGLVRRPLREVSGLLKRRFHWTAPTALQVTVRDAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVV
SHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtatctggcttggtgcggagaccccttcgagaggtctccgggctgctgaag
aggcgctttcactggaccgccccgactgcgctgcaggtgacagttcgtgatgctataaat
cagggtatggatgaggagctggaaagagatgagaaggtatttctgcttggagaagaagtt
gcccagtacgatggggcatacaaggttagtcgagggctgtggaagaaatatggagacaag
aggattattgacactcccatatcagagatgggctttgctggaattgctgtaggtgcagct
atggctgggttgcggcccatttgtgaatttatgaccttcaatttctccatgcaagccatt
gaccaggttataaactcagctgccaagacctactacatgtctggtggccttcagcctgtg
cctatagtcttcagggggcccaatggtgcctcagcaggtgtagctgcccagcactcacag
tgctttgctgcctggtatgggcactgcccaggcttaaaggtggtcagtccctggaattca
gaggatgctaaaggacttattaaatcagccattcgggataacaatccagtcgtggtgcta
gagaatgaattgatgtatggggttccttttgaatttcctccggaagctcagtcaaaagat
tttctgattcctattggaaaagccaaaatagaaaggcaaggaacacatataactgtggtt
tcccattcgagacctgtgggccactgcttagaagctgcagcagtgctatctaaagaggga
gttgaatgtgaggtgataaatatgcgtaccatcagaccaatggacatggaaaccatagaa
gccagtgtcatgaagacaaatcatctcgtaactgtggaaggaggctggccacagtttgga
gtaggagctgaaatctgtgccaggatcatggaaggtcctgcgttcaatttcctggatgct
cctgctgttcgtgtcactggtgctgacgtccctatgccttatgcaaagattctagaagac
aactctatacctcaggtcaaagacatcatatttgcaataaagaaaacattaaatatttag
DBGET
integrated database retrieval system
