Macaca mulatta (rhesus monkey): 574360 Help Entry 574360            CDS       T01028                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 precursor   KO K10160   toll-like receptor 4 Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc04064   NF-kappa B signaling pathway mcc04066   HIF-1 signaling pathway mcc04145   Phagosome mcc04151   PI3K-Akt signaling pathway mcc04217   Necroptosis mcc04613   Neutrophil extracellular trap formation mcc04620   Toll-like receptor signaling pathway mcc04621   NOD-like receptor signaling pathway mcc04936   Alcoholic liver disease mcc05132   Salmonella infection mcc05133   Pertussis mcc05134   Legionellosis mcc05135   Yersinia infection mcc05140   Leishmaniasis mcc05142   Chagas disease mcc05144   Malaria mcc05145   Toxoplasmosis mcc05146   Amoebiasis mcc05152   Tuberculosis mcc05161   Hepatitis B mcc05162   Measles mcc05164   Influenza A mcc05170   Human immunodeficiency virus 1 infection mcc05171   Coronavirus disease - COVID-19 mcc05205   Proteoglycans in cancer mcc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mcc05321   Inflammatory bowel disease mcc05323   Rheumatoid arthritis mcc05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mcc00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     574360 (TLR4)    04066 HIF-1 signaling pathway     574360 (TLR4)    04151 PI3K-Akt signaling pathway     574360 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     574360 (TLR4)   09143 Cell growth and death    04217 Necroptosis     574360 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     574360 (TLR4)    04620 Toll-like receptor signaling pathway     574360 (TLR4)    04621 NOD-like receptor signaling pathway     574360 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     574360 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     574360 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     574360 (TLR4)    05161 Hepatitis B     574360 (TLR4)    05171 Coronavirus disease - COVID-19     574360 (TLR4)    05164 Influenza A     574360 (TLR4)    05162 Measles     574360 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     574360 (TLR4)    05135 Yersinia infection     574360 (TLR4)    05133 Pertussis     574360 (TLR4)    05134 Legionellosis     574360 (TLR4)    05152 Tuberculosis     574360 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     574360 (TLR4)    05144 Malaria     574360 (TLR4)    05145 Toxoplasmosis     574360 (TLR4)    05140 Leishmaniasis     574360 (TLR4)    05142 Chagas disease     574360 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     574360 (TLR4)    05321 Inflammatory bowel disease     574360 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     574360 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     574360 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcc04131]     574360 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:mcc04054]     574360 (TLR4)    04090 CD molecules [BR:mcc04090]     574360 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:mcc00536]     574360 (TLR4) Membrane trafficking [BR:mcc04131]  Endocytosis   Phagocytosis    Toll-like receptors     574360 (TLR4) Pattern recognition receptors [BR:mcc04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    574360 (TLR4) CD molecules [BR:mcc04090]  Proteins   574360 (TLR4) Glycosaminoglycan binding proteins [BR:mcc00536]  Hyaluronan   Cell surface receptors    574360 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_1 LRR_14 TIR_2 LRR_9 LRR_5 LRR_6 LRR_Zer-1 LRR_EndoS ThsB_TIR LRR_R13L1-DRL21 Curto_V2 Motif Other DBs NCBI-GeneID:  574360 NCBI-ProteinID:  NP_001032169 Ensembl:  ENSMMUG00000009112 UniProt:  B3Y632 A0A8J8XMT1 LinkDB All DBs Position 15:complement(25088083..25105816) Genome browser AA seq 826 aa AA seqDB search MTSALRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELKFYKIPDNIPFSTKNLD LSFNPLRHLGSYSFLRFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALG AFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHL DLSSNKIQNIYCKDLQVLHQMPLSNLSLDLSLNPINFIQPGAFKEIRLHKLTLRSNFDDL NVMKTCIQGLAGLEVHRLVLGEFRNERNLEEFDKSSLEGLCNLTIEEFRLTYLDYYLDNI IDLFNCLANVSSFSLVSVSIKRVEDFSYNFRWQHLELVNCKFEQFPTLELESLKRLTFTA NKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNDVITMSSNFLG LEKLEHLDFQHSNLKQMSQFSVFLSLRNLIYLDISHTHTRVAFNGIFDGLLSLKVLKMAG NSFQENFLPDIFTDLKNLTFLDLSQCQLEQLSPTAFDTLNKLQVLNMSHNNFFSLDTFPY KCLPSLQVLDYSLNHIMTSNNQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQL LVEAERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVFSVLVVSVVAVLVYKFYFHLML LAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLR QQVELYRLLSRNTYLEWEDSVLGQHIFWRRLRKALLDGRSWNPEEQ NT seq 2481 nt NT seq  +upstreamnt  +downstreamnt atgacgtctgccttgcgcctggctgggactctgatcccagccatggccttcctctcctgc gtgagaccagaaagctgggagccctgcgtggaggtggttcctaacattacttatcaatgc atggagctgaagttctacaaaatccccgacaacatccccttctcaaccaagaacctggac ctgagctttaatcccctgaggcatttaggcagctatagcttcctccgttttccagaactg caggtgctggatttatccaggtgtgaaatccagacaattgaagatggggcatatcagagc ctaagccacctctccactttaatattgacaggaaaccccatccagagtttagccctggga gccttttctggactatcaagtttacagaagctggtggctgtggagacaaatctagcatct ctagagaacttccccattggacatctcaaaactttgaaagaacttaatgtggctcacaat cttatccagtctttcaaattacctgagtatttttctaatctgaccaatctagagcacttg gacctttccagtaacaagattcaaaatatttattgcaaagacttgcaggttctacatcaa atgcccctatccaatctctctttagacctgtccctgaaccctataaactttatccaacca ggtgcatttaaagaaattaggcttcataagctgactttgagaagtaattttgatgattta aatgtaatgaaaacttgtattcaaggtctggctggtttagaagtccatcgtttggttctg ggagaatttagaaatgaaagaaacttggaagagtttgacaaatcttctctggagggattg tgcaatttgaccattgaagaattccgattaacatacttagactactacctcgataatatt attgacttatttaattgtttggcaaatgtttcttcattttccctggtgagtgtgagtatt aaaagggtagaagacttttcttataatttcagatggcaacatttagaattagttaactgt aaatttgaacagtttcccacattggaactcgaatctctcaaaaggcttactttcactgcc aacaaaggtgggaatgctttttcagaagttgatctaccaagccttgagtttctagatctc agtagaaatggcttgagtttcaaaggttgctgttctcaaagtgattttgggacaaccagc ctaaagtatttagatctgagcttcaatgatgttattaccatgagttcaaacttcttgggc ttagaaaaactagaacatctggatttccagcattccaatttgaaacagatgagtcaattt tcagtattcctatcactcagaaacctcatttaccttgacatttctcatactcacaccaga gttgctttcaatggcatcttcgatggcttgctcagtctcaaagtcttaaaaatggctggc aattctttccaggaaaacttccttccagatatcttcacagatctgaaaaacttgaccttc ctggacctctctcagtgtcaattggagcagttgtctccaacagcatttgacacactcaac aagcttcaggtactaaatatgagccacaacaacttcttttcattggatacgtttccttat aagtgtctgccctccctccaggttctcgattacagtctcaatcacataatgacttccaac aaccaggaactacagcattttccaagtagtctagctttcttaaatcttactcagaatgac tttgcttgtacttgtgaacaccagagtttcctgcagtggatcaaggaccagaggcagctc ttggtggaagctgaacgaatggaatgtgcaacaccttcagataaacagggcatgccggtg ctgagtttgaatattacctgtcagatgaataagaccatcattggtgtgtctgtgttcagt gtgcttgtggtatctgttgtagcagttctggtctataagttctattttcacctgatgctt cttgctggctgcataaagtatggtagaggtgaaaacatctatgatgcctttgttatctac tcaagccaggatgaggactgggtaaggaatgaactagtaaagaatttagaagaaggggtg cctccctttcagctctgccttcactacagagactttattcccggtgtggccattgctgca aacatcatccatgaaggtttccataaaagccgaaaggtgattgttgtggtgtcccagcac ttcatccagagccgctggtgtatctttgaatatgagattgctcagacctggcagtttctg agcagtcgtgcaggcataatcttcattgtcctgcagaaggtggagaagaccctgctcagg cagcaggtggagctgtaccgccttctcagcaggaacacttacctggagtgggaggacagt gtcctggggcagcacatcttctggagacgactcagaaaagccctgttggatggcagatcg tggaatccagaagaacagtag

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