Macaca mulatta (rhesus monkey): 678693
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Entry
678693 CDS
T01028
Symbol
CYP17A1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase precursor
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00140
Steroid hormone biosynthesis
mcc01100
Metabolic pathways
mcc04913
Ovarian steroidogenesis
mcc04917
Prolactin signaling pathway
mcc04927
Cortisol synthesis and secretion
mcc04934
Cushing syndrome
Module
mcc_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
mcc_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
mcc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
mcc_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
678693 (CYP17A1)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
678693 (CYP17A1)
04917 Prolactin signaling pathway
678693 (CYP17A1)
04927 Cortisol synthesis and secretion
678693 (CYP17A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
678693 (CYP17A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
mcc00199
]
678693 (CYP17A1)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
678693 (CYP17A1)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
678693 (CYP17A1)
Cytochrome P450 [BR:
mcc00199
]
Cytochrome P450, animal type
CYP17 family
678693 (CYP17A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
p450
BBP1_C
Motif
Other DBs
NCBI-GeneID:
678693
NCBI-ProteinID:
NP_001035322
Ensembl:
ENSMMUG00000017601
UniProt:
Q8HYM9
Q5IFH9
LinkDB
All DBs
Position
9:complement(<103372364..103379292)
Genome browser
AA seq
508 aa
AA seq
DB search
MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKY
GPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQVTTLDILSNNRKGIAFADYGAH
WQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQTIDISFPVFVAITNVIS
LICFNISYKNGDPELKIVHNYNEGIIDSLGKESLVDLFPWLKVFPNKTLEKLKRHVKTRN
DLLTKIFENYKEKFHSDSITNMLDVLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIF
GAGVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREV
LRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQPDQFMPERFLNP
AGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGNP
KVVFLIDSFKVKIKVRQAWREAQAEGST
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtgggagcttgtggctctcttgctgctcaccctagcctatttattttggcccaagaga
aggtgccctggtgccaagtatcctaagagcctcctgtccctgcccctggtgggcagcctg
ccattcctccccagacatggccatatgcataacaactttttcaagctgcagaaaaaatat
ggccccatctattccgttcgtatgggcaccaagactacagtgattgttggccaccaccag
ctggccaaggaggtgcttattaagaagggcaaggacttctctgggcggcctcaagtgaca
actctagacatcctgtccaacaatcgtaagggtattgccttcgctgactacggcgcacat
tggcagctgcatcgaaggctggcgatggccacctttgccctgttcaaggatggcgatcag
aagctggagaagatcatttgtcaggaaatcagtacattgtgtgatatgctggccacccac
aacggacagaccatagacatctcctttcctgtcttcgtggcgataaccaatgtcatctcc
ttgatctgcttcaacatctcctacaagaatggggaccctgagttgaagatcgtacataat
tacaatgaaggcatcatagacagcctgggcaaggagagcctggtggacctattcccctgg
ttgaaggttttccccaacaaaactctggaaaaattaaagaggcatgttaaaacacgaaat
gatctgctgactaaaatatttgaaaattacaaggagaaattccacagcgactctatcacc
aacatgctggacgtactgatgcaagccaagatgaattcagataatggcaacgctggccca
gatcaagactcagagctgctttcagataaccacattctcaccaccataggggacatcttt
ggggctggcgtggagaccaccacctctgtggtgaaatggatcgtggccttcctgctgcac
aatcctcaggtgaagaagaagctctacgaggagattgaccagaatgtgggtttcagccgc
acaccaaccatcagtgaccgtaaccgtctcctcctgctggaggccaccatccgagaggtg
cttcgcatcaggcccgtggcccctatgctcatcccccacaaggccaacgttgactccagc
atcggtgagtttgctgtggacaagggcacacacgttatcatcaatctgtgggcgctgcat
cacaatgagaaggagtggcaccagccggaccagttcatgcctgagcgtttcttgaatcca
gcggggacccagcttatctcaccatcattaagctacttgcccttcggagcaggacctcgc
tcctgtataggtgagatcctggcccgccaggagctcttcctcatcatggcctggctgctg
cagaggttcgacctggaggtaccagatgatgggcagctgccctccctggaaggcaaccca
aaggtggtctttctgatcgactctttcaaagtgaagatcaaggtgcgccaggcctggagg
gaagcccaggctgagggtagcacctaa
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